Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2054
Gene name Gene Name - the full gene name approved by the HGNC.
Syntaxin 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STX2
Synonyms (NCBI Gene) Gene synonyms aliases
EPIM, EPM, STX2A, STX2B, STX2C
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q24.33
Summary Summary of gene provided in NCBI Entrez Gene.
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002690 hsa-miR-124-3p Microarray 15685193
MIRT052827 hsa-miR-3200-3p CLASH 23622248
MIRT680922 hsa-miR-1247-3p HITS-CLIP 23706177
MIRT680921 hsa-miR-3160-3p HITS-CLIP 23706177
MIRT680920 hsa-miR-558 HITS-CLIP 23706177
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA 21873635
GO:0005198 Function Structural molecule activity IDA 22226963
GO:0005484 Function SNAP receptor activity IBA 21873635
GO:0005515 Function Protein binding IPI 12773094
GO:0005615 Component Extracellular space IDA 22226963
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
132350 3403 ENSG00000111450
Protein
UniProt ID P32856
Protein name Syntaxin-2 (Epimorphin)
Protein function Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00804 Syntaxin 29 226 Syntaxin Domain
PF05739 SNARE 227 279 SNARE domain Family
Sequence
Sequence length 288
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  SNARE interactions in vesicular transport
Synaptic vesicle cycle
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
29064472
Unknown
Disease term Disease name Evidence References Source
Spermatogenic Failure spermatogenic failure GenCC
Glioblastoma Glioblastoma CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 28800327
Blood Coagulation Disorders Associate 12540565
Carcinoma Renal Cell Associate 33247676
Carotid Artery Thrombosis Associate 21156930
Chemical and Drug Induced Liver Injury Associate 27362846
Colitis Stimulate 10024592
Colitis Associate 12149388
Diarrhea Associate 12380901, 20219084, 25428148, 29765909
Diarrhea Stimulate 32946720
Drug Related Side Effects and Adverse Reactions Associate 10024592