AK4 (adenylate kinase 4)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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205 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Adenylate kinase 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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AK4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AK 4, AK3, AK3L1, AK3L2 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p31.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible trans |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | P27144 | |||||||||||||||
Protein name | Adenylate kinase 4, mitochondrial (EC 2.7.4.4) (EC 2.7.4.6) (Adenylate kinase 3-like) (GTP:AMP phosphotransferase AK4) | |||||||||||||||
Protein function | Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions (PubMed:19073142, PubMed:19766732, PubMed:23416111, PubMed:24767988). Similar to other ad | |||||||||||||||
PDB | 2AR7 , 2BBW , 3NDP | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain. {ECO:0000269|PubMed:11485571}. | |||||||||||||||
Sequence |
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Sequence length | 223 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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