SLC44A5 (solute carrier family 44 member 5)

Gene

• Entrez ID: 204962
• Gene name: Solute carrier family 44 member 5
• Gene symbol: SLC44A5
• Synonyms (NCBI Gene): CTL5
• Chromosome: 1
• Chromosome location: 1p31.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019121	hsa-miR-335-5p	Microarray	18185580
MIRT1364462	hsa-miR-1264	CLIP-seq
MIRT1364463	hsa-miR-224	CLIP-seq
MIRT1364464	hsa-miR-23a	CLIP-seq
MIRT1364465	hsa-miR-23b	CLIP-seq
MIRT1364466	hsa-miR-23c	CLIP-seq
MIRT1364467	hsa-miR-298	CLIP-seq
MIRT1364468	hsa-miR-3121-5p	CLIP-seq
MIRT1364469	hsa-miR-3158-5p	CLIP-seq
MIRT1364470	hsa-miR-3185	CLIP-seq
MIRT1364471	hsa-miR-3682-3p	CLIP-seq
MIRT1364472	hsa-miR-384	CLIP-seq
MIRT1364473	hsa-miR-4446-5p	CLIP-seq
MIRT1364474	hsa-miR-4502	CLIP-seq
MIRT1364475	hsa-miR-4509	CLIP-seq
MIRT1364476	hsa-miR-450b-5p	CLIP-seq
MIRT1364477	hsa-miR-4744	CLIP-seq
MIRT1364478	hsa-miR-4753-3p	CLIP-seq
MIRT1364479	hsa-miR-4755-5p	CLIP-seq
MIRT1364480	hsa-miR-4768-5p	CLIP-seq
MIRT1364481	hsa-miR-670	CLIP-seq
MIRT1364482	hsa-miR-802	CLIP-seq
MIRT1922383	hsa-miR-4775	CLIP-seq
MIRT2331971	hsa-miR-1305	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005886	Component	Plasma membrane	TAS
GO:0006656	Process	Phosphatidylcholine biosynthetic process	TAS
GO:0016020	Component	Membrane	IBA	21873635
GO:0016021	Component	Integral component of membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IBA	21873635
GO:0055085	Process	Transmembrane transport	IBA	21873635
GO:0055085	Process	Transmembrane transport	TAS

Other IDs

• MIM: 620329
• HGNC: 28524
• e!Ensembl: ENSG00000137968

Protein

• UniProt ID: Q8NCS7
• Protein name: Choline transporter-like protein 5 (Solute carrier family 44 member 5)
• Protein function: Choline/H+ antiporter.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04515	Choline_transpo	330 → 687	Plasma-membrane choline transporter	Family

• Sequence:

  MNDTEKPADTPSEEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAW
  VHGDPRRAAYPTDSQGHFCGQKGTPNENKTILFYFNLLRCTSPSVLLNLQCPTTQICVSK
  CPEKFLTYVEMQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSKPFLQ
  RCFPDFSTKNGTLTIGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYAR
  TWYWILIGLTIAMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERP
  SSVLTIYDIGIQTNISMYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEG
  SKAIGYVPSTLVYPALTFILLSICICYWVVTAVFLATSGVPVYKVIAPGGHCIHENQTCD
  PEIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALA
  GAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRL
  KRTQNTLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVL
  KVAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGS
  YLIAHGFFSVYAMCVETIFICFCEDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE

• Sequence length: 719

Pathways

KEGG:

Choline metabolism in cancer

Reactome:

Synthesis of PC
Transport of bile salts and organic acids, metal ions and amine compounds

Associated diseases

Unknown
Disease term	Disease name	Evidence	References	Source
Mental depression	Major Depressive Disorder		29942085	ClinVar
Neuroticism	Neuroticism			GWAS