CTTN (cortactin)

Gene

• Entrez ID: 2017
• Gene name: Cortactin
• Gene symbol: CTTN
• Synonyms (NCBI Gene): EMS1
• Chromosome: 11
• Chromosome location: 11q13.3
• Summary: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019566	hsa-miR-340-5p	Sequencing	20371350
MIRT023872	hsa-miR-1-3p	Proteomics	18668040
MIRT023872	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT025473	hsa-miR-34a-5p	Proteomics	21566225
MIRT025473	hsa-miR-34a-5p	Proteomics	21566225
MIRT049499	hsa-miR-92a-3p	CLASH	23622248
MIRT045376	hsa-miR-185-5p	CLASH	23622248
MIRT569538	hsa-miR-6890-3p	PAR-CLIP	20371350
MIRT569537	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT569536	hsa-miR-2467-5p	PAR-CLIP	20371350
MIRT569534	hsa-miR-4706	PAR-CLIP	20371350
MIRT569535	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT569533	hsa-miR-1908-5p	PAR-CLIP	20371350
MIRT569532	hsa-miR-663a	PAR-CLIP	20371350
MIRT569531	hsa-miR-6787-5p	PAR-CLIP	20371350
MIRT060616	hsa-miR-448	PAR-CLIP	21572407
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	21572407
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	21572407
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	21572407
MIRT060617	hsa-miR-495-5p	PAR-CLIP	21572407
MIRT478514	hsa-miR-382-5p	PAR-CLIP	21572407
MIRT478513	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT478512	hsa-miR-3163	PAR-CLIP	21572407
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	21572407
MIRT060619	hsa-miR-4317	PAR-CLIP	21572407
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	21572407
MIRT060615	hsa-miR-153-3p	PAR-CLIP	21572407
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	21572407
MIRT060616	hsa-miR-448	PAR-CLIP	23446348
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	23446348
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	23446348
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	23446348
MIRT060617	hsa-miR-495-5p	PAR-CLIP	23446348
MIRT478514	hsa-miR-382-5p	PAR-CLIP	23446348
MIRT478513	hsa-miR-338-5p	PAR-CLIP	23446348
MIRT478512	hsa-miR-3163	PAR-CLIP	23446348
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	23446348
MIRT060619	hsa-miR-4317	PAR-CLIP	23446348
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	23446348
MIRT060615	hsa-miR-153-3p	PAR-CLIP	23446348
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	23446348
MIRT060616	hsa-miR-448	PAR-CLIP	23592263
MIRT478519	hsa-miR-548aa	PAR-CLIP	23592263
MIRT478518	hsa-miR-548ap-3p	PAR-CLIP	23592263
MIRT478517	hsa-miR-548t-3p	PAR-CLIP	23592263
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	23592263
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	23592263
MIRT060617	hsa-miR-495-5p	PAR-CLIP	23592263
MIRT478514	hsa-miR-382-5p	PAR-CLIP	23592263
MIRT478513	hsa-miR-338-5p	PAR-CLIP	23592263
MIRT478512	hsa-miR-3163	PAR-CLIP	23592263
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT060619	hsa-miR-4317	PAR-CLIP	23592263
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	23592263
MIRT060615	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	23592263
MIRT732177	hsa-miR-542-3p	Luciferase reporter assay, qRT-PCR, Western blot	26952924
MIRT732177	hsa-miR-542-3p	Luciferase reporter assay, qRT-PCR, Western blot	26952924
MIRT569538	hsa-miR-6890-3p	PAR-CLIP	20371350
MIRT569537	hsa-miR-4768-3p	PAR-CLIP	20371350
MIRT569536	hsa-miR-2467-5p	PAR-CLIP	20371350
MIRT569534	hsa-miR-4706	PAR-CLIP	20371350
MIRT569535	hsa-miR-4749-5p	PAR-CLIP	20371350
MIRT569533	hsa-miR-1908-5p	PAR-CLIP	20371350
MIRT569532	hsa-miR-663a	PAR-CLIP	20371350
MIRT569531	hsa-miR-6787-5p	PAR-CLIP	20371350
MIRT060616	hsa-miR-448	PAR-CLIP	21572407
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	21572407
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	21572407
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	21572407
MIRT060617	hsa-miR-495-5p	PAR-CLIP	21572407
MIRT478514	hsa-miR-382-5p	PAR-CLIP	21572407
MIRT478513	hsa-miR-338-5p	PAR-CLIP	21572407
MIRT478512	hsa-miR-3163	PAR-CLIP	21572407
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	21572407
MIRT060619	hsa-miR-4317	PAR-CLIP	21572407
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	21572407
MIRT060615	hsa-miR-153-3p	PAR-CLIP	21572407
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	21572407
MIRT060616	hsa-miR-448	PAR-CLIP	23446348
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	23446348
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	23446348
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	23446348
MIRT060617	hsa-miR-495-5p	PAR-CLIP	23446348
MIRT478514	hsa-miR-382-5p	PAR-CLIP	23446348
MIRT478513	hsa-miR-338-5p	PAR-CLIP	23446348
MIRT478512	hsa-miR-3163	PAR-CLIP	23446348
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	23446348
MIRT060619	hsa-miR-4317	PAR-CLIP	23446348
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	23446348
MIRT060615	hsa-miR-153-3p	PAR-CLIP	23446348
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	23446348
MIRT060616	hsa-miR-448	PAR-CLIP	23592263
MIRT478519	hsa-miR-548aa	PAR-CLIP	23592263
MIRT478518	hsa-miR-548ap-3p	PAR-CLIP	23592263
MIRT478517	hsa-miR-548t-3p	PAR-CLIP	23592263
MIRT060621	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT478516	hsa-miR-548at-3p	PAR-CLIP	23592263
MIRT478515	hsa-miR-548ay-3p	PAR-CLIP	23592263
MIRT060617	hsa-miR-495-5p	PAR-CLIP	23592263
MIRT478514	hsa-miR-382-5p	PAR-CLIP	23592263
MIRT478513	hsa-miR-338-5p	PAR-CLIP	23592263
MIRT478512	hsa-miR-3163	PAR-CLIP	23592263
MIRT478511	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT060619	hsa-miR-4317	PAR-CLIP	23592263
MIRT060623	hsa-miR-6847-3p	PAR-CLIP	23592263
MIRT060615	hsa-miR-153-3p	PAR-CLIP	23592263
MIRT060618	hsa-miR-1178-3p	PAR-CLIP	23592263
MIRT916093	hsa-miR-3613-3p	CLIP-seq
MIRT916094	hsa-miR-4427	CLIP-seq
MIRT916095	hsa-miR-4452	CLIP-seq
MIRT916096	hsa-miR-4680-3p	CLIP-seq
MIRT916097	hsa-miR-4775	CLIP-seq
MIRT916098	hsa-miR-4778-5p	CLIP-seq
MIRT916099	hsa-miR-487a	CLIP-seq
MIRT916100	hsa-miR-548c-3p	CLIP-seq
MIRT916101	hsa-miR-1185	CLIP-seq
MIRT916102	hsa-miR-1224-3p	CLIP-seq
MIRT916103	hsa-miR-1224-5p	CLIP-seq
MIRT916104	hsa-miR-1271	CLIP-seq
MIRT916105	hsa-miR-1294	CLIP-seq
MIRT916106	hsa-miR-142-3p	CLIP-seq
MIRT916107	hsa-miR-143	CLIP-seq
MIRT916108	hsa-miR-182	CLIP-seq
MIRT916109	hsa-miR-1908	CLIP-seq
MIRT916110	hsa-miR-3130-3p	CLIP-seq
MIRT916111	hsa-miR-3132	CLIP-seq
MIRT916112	hsa-miR-3137	CLIP-seq
MIRT916113	hsa-miR-3145-3p	CLIP-seq
MIRT916114	hsa-miR-3605-5p	CLIP-seq
MIRT916093	hsa-miR-3613-3p	CLIP-seq
MIRT916115	hsa-miR-3679-5p	CLIP-seq
MIRT916116	hsa-miR-377	CLIP-seq
MIRT916117	hsa-miR-4286	CLIP-seq
MIRT916118	hsa-miR-4290	CLIP-seq
MIRT916119	hsa-miR-4316	CLIP-seq
MIRT916120	hsa-miR-4325	CLIP-seq
MIRT916121	hsa-miR-4451	CLIP-seq
MIRT916122	hsa-miR-4459	CLIP-seq
MIRT916123	hsa-miR-4470	CLIP-seq
MIRT916124	hsa-miR-4530	CLIP-seq
MIRT916125	hsa-miR-4660	CLIP-seq
MIRT916126	hsa-miR-4661-3p	CLIP-seq
MIRT916127	hsa-miR-4685-5p	CLIP-seq
MIRT916128	hsa-miR-4687-5p	CLIP-seq
MIRT916129	hsa-miR-4751	CLIP-seq
MIRT916130	hsa-miR-4770	CLIP-seq
MIRT916131	hsa-miR-4779	CLIP-seq
MIRT916132	hsa-miR-4783-3p	CLIP-seq
MIRT916133	hsa-miR-4793-3p	CLIP-seq
MIRT916134	hsa-miR-648	CLIP-seq
MIRT916135	hsa-miR-663	CLIP-seq
MIRT916136	hsa-miR-765	CLIP-seq
MIRT916137	hsa-miR-96	CLIP-seq
MIRT916138	hsa-miR-1283	CLIP-seq
MIRT916139	hsa-miR-3614-3p	CLIP-seq
MIRT916116	hsa-miR-377	CLIP-seq
MIRT916140	hsa-miR-3908	CLIP-seq
MIRT916141	hsa-miR-3938	CLIP-seq
MIRT916142	hsa-miR-4422	CLIP-seq
MIRT916143	hsa-miR-4711-5p	CLIP-seq
MIRT916144	hsa-miR-545	CLIP-seq
MIRT916145	hsa-miR-548l	CLIP-seq
MIRT916146	hsa-miR-548n	CLIP-seq
MIRT916147	hsa-miR-548p	CLIP-seq
MIRT1971652	hsa-miR-1182	CLIP-seq
MIRT916103	hsa-miR-1224-5p	CLIP-seq
MIRT916104	hsa-miR-1271	CLIP-seq
MIRT916107	hsa-miR-143	CLIP-seq
MIRT916108	hsa-miR-182	CLIP-seq
MIRT1971653	hsa-miR-210	CLIP-seq
MIRT916111	hsa-miR-3132	CLIP-seq
MIRT916113	hsa-miR-3145-3p	CLIP-seq
MIRT1971654	hsa-miR-3148	CLIP-seq
MIRT916121	hsa-miR-4451	CLIP-seq
MIRT916122	hsa-miR-4459	CLIP-seq
MIRT916123	hsa-miR-4470	CLIP-seq
MIRT1971655	hsa-miR-4481	CLIP-seq
MIRT916143	hsa-miR-4711-5p	CLIP-seq
MIRT1971656	hsa-miR-4745-5p	CLIP-seq
MIRT916129	hsa-miR-4751	CLIP-seq
MIRT916130	hsa-miR-4770	CLIP-seq
MIRT916131	hsa-miR-4779	CLIP-seq
MIRT1971657	hsa-miR-520a-5p	CLIP-seq
MIRT1971658	hsa-miR-525-5p	CLIP-seq
MIRT1971659	hsa-miR-548ac	CLIP-seq
MIRT1971660	hsa-miR-548d-3p	CLIP-seq
MIRT1971661	hsa-miR-548z	CLIP-seq
MIRT1971662	hsa-miR-744	CLIP-seq
MIRT916136	hsa-miR-765	CLIP-seq
MIRT916137	hsa-miR-96	CLIP-seq
MIRT916109	hsa-miR-1908	CLIP-seq
MIRT916143	hsa-miR-4711-5p	CLIP-seq
MIRT916135	hsa-miR-663	CLIP-seq
MIRT1971652	hsa-miR-1182	CLIP-seq
MIRT2510611	hsa-miR-1207-5p	CLIP-seq
MIRT916103	hsa-miR-1224-5p	CLIP-seq
MIRT2510612	hsa-miR-1262	CLIP-seq
MIRT916104	hsa-miR-1271	CLIP-seq
MIRT2510613	hsa-miR-1285	CLIP-seq
MIRT2510614	hsa-miR-1343	CLIP-seq
MIRT916107	hsa-miR-143	CLIP-seq
MIRT916108	hsa-miR-182	CLIP-seq
MIRT2510615	hsa-miR-183	CLIP-seq
MIRT916109	hsa-miR-1908	CLIP-seq
MIRT2510616	hsa-miR-1909	CLIP-seq
MIRT2510617	hsa-miR-1915	CLIP-seq
MIRT2510618	hsa-miR-208a	CLIP-seq
MIRT2510619	hsa-miR-208b	CLIP-seq
MIRT1971653	hsa-miR-210	CLIP-seq
MIRT2510620	hsa-miR-224	CLIP-seq
MIRT2510621	hsa-miR-2278	CLIP-seq
MIRT2510622	hsa-miR-3115	CLIP-seq
MIRT2510623	hsa-miR-3117-5p	CLIP-seq
MIRT916110	hsa-miR-3130-3p	CLIP-seq
MIRT916111	hsa-miR-3132	CLIP-seq
MIRT2510624	hsa-miR-3136-3p	CLIP-seq
MIRT916113	hsa-miR-3145-3p	CLIP-seq
MIRT1971654	hsa-miR-3148	CLIP-seq
MIRT2510625	hsa-miR-3167	CLIP-seq
MIRT2510626	hsa-miR-3187-5p	CLIP-seq
MIRT2510627	hsa-miR-329	CLIP-seq
MIRT2510628	hsa-miR-3611	CLIP-seq
MIRT916139	hsa-miR-3614-3p	CLIP-seq
MIRT2510629	hsa-miR-3617	CLIP-seq
MIRT2510630	hsa-miR-3619-3p	CLIP-seq
MIRT2510631	hsa-miR-362-3p	CLIP-seq
MIRT2510632	hsa-miR-3661	CLIP-seq
MIRT2510633	hsa-miR-3667-3p	CLIP-seq
MIRT916116	hsa-miR-377	CLIP-seq
MIRT2510634	hsa-miR-3913-3p	CLIP-seq
MIRT2510635	hsa-miR-3922-5p	CLIP-seq
MIRT2510636	hsa-miR-3945	CLIP-seq
MIRT2510637	hsa-miR-4253	CLIP-seq
MIRT2510638	hsa-miR-4269	CLIP-seq
MIRT2510639	hsa-miR-4276	CLIP-seq
MIRT2510640	hsa-miR-4284	CLIP-seq
MIRT916118	hsa-miR-4290	CLIP-seq
MIRT2510641	hsa-miR-4297	CLIP-seq
MIRT916120	hsa-miR-4325	CLIP-seq
MIRT916121	hsa-miR-4451	CLIP-seq
MIRT916122	hsa-miR-4459	CLIP-seq
MIRT2510642	hsa-miR-4467	CLIP-seq
MIRT916123	hsa-miR-4470	CLIP-seq
MIRT1971655	hsa-miR-4481	CLIP-seq
MIRT2510643	hsa-miR-4504	CLIP-seq
MIRT916124	hsa-miR-4530	CLIP-seq
MIRT2510644	hsa-miR-4645-3p	CLIP-seq
MIRT916128	hsa-miR-4687-5p	CLIP-seq
MIRT2510645	hsa-miR-4690-5p	CLIP-seq
MIRT2510646	hsa-miR-4701-3p	CLIP-seq
MIRT916143	hsa-miR-4711-5p	CLIP-seq
MIRT2510647	hsa-miR-4724-5p	CLIP-seq
MIRT1971656	hsa-miR-4745-5p	CLIP-seq
MIRT916129	hsa-miR-4751	CLIP-seq
MIRT2510648	hsa-miR-4763-3p	CLIP-seq
MIRT916130	hsa-miR-4770	CLIP-seq
MIRT916131	hsa-miR-4779	CLIP-seq
MIRT916132	hsa-miR-4783-3p	CLIP-seq
MIRT916133	hsa-miR-4793-3p	CLIP-seq
MIRT2510649	hsa-miR-486-3p	CLIP-seq
MIRT2510650	hsa-miR-498	CLIP-seq
MIRT2510651	hsa-miR-499-5p	CLIP-seq
MIRT1971657	hsa-miR-520a-5p	CLIP-seq
MIRT1971658	hsa-miR-525-5p	CLIP-seq
MIRT1971659	hsa-miR-548ac	CLIP-seq
MIRT1971660	hsa-miR-548d-3p	CLIP-seq
MIRT1971661	hsa-miR-548z	CLIP-seq
MIRT2510652	hsa-miR-593	CLIP-seq
MIRT2510653	hsa-miR-603	CLIP-seq
MIRT2510654	hsa-miR-606	CLIP-seq
MIRT2510655	hsa-miR-612	CLIP-seq
MIRT2510656	hsa-miR-631	CLIP-seq
MIRT2510657	hsa-miR-641	CLIP-seq
MIRT916135	hsa-miR-663	CLIP-seq
MIRT2510658	hsa-miR-663b	CLIP-seq
MIRT1971662	hsa-miR-744	CLIP-seq
MIRT2510659	hsa-miR-758	CLIP-seq
MIRT916136	hsa-miR-765	CLIP-seq
MIRT2510660	hsa-miR-876-5p	CLIP-seq
MIRT2510661	hsa-miR-922	CLIP-seq
MIRT916137	hsa-miR-96	CLIP-seq
MIRT1971652	hsa-miR-1182	CLIP-seq
MIRT2510611	hsa-miR-1207-5p	CLIP-seq
MIRT916103	hsa-miR-1224-5p	CLIP-seq
MIRT2510612	hsa-miR-1262	CLIP-seq
MIRT916104	hsa-miR-1271	CLIP-seq
MIRT2510613	hsa-miR-1285	CLIP-seq
MIRT2510614	hsa-miR-1343	CLIP-seq
MIRT916107	hsa-miR-143	CLIP-seq
MIRT916108	hsa-miR-182	CLIP-seq
MIRT2510615	hsa-miR-183	CLIP-seq
MIRT916109	hsa-miR-1908	CLIP-seq
MIRT2510616	hsa-miR-1909	CLIP-seq
MIRT2510617	hsa-miR-1915	CLIP-seq
MIRT2510618	hsa-miR-208a	CLIP-seq
MIRT2510619	hsa-miR-208b	CLIP-seq
MIRT1971653	hsa-miR-210	CLIP-seq
MIRT2510620	hsa-miR-224	CLIP-seq
MIRT2510621	hsa-miR-2278	CLIP-seq
MIRT2510622	hsa-miR-3115	CLIP-seq
MIRT2510623	hsa-miR-3117-5p	CLIP-seq
MIRT916110	hsa-miR-3130-3p	CLIP-seq
MIRT916111	hsa-miR-3132	CLIP-seq
MIRT2510624	hsa-miR-3136-3p	CLIP-seq
MIRT916113	hsa-miR-3145-3p	CLIP-seq
MIRT1971654	hsa-miR-3148	CLIP-seq
MIRT2510625	hsa-miR-3167	CLIP-seq
MIRT2510626	hsa-miR-3187-5p	CLIP-seq
MIRT2510627	hsa-miR-329	CLIP-seq
MIRT2510628	hsa-miR-3611	CLIP-seq
MIRT916139	hsa-miR-3614-3p	CLIP-seq
MIRT2510629	hsa-miR-3617	CLIP-seq
MIRT2510630	hsa-miR-3619-3p	CLIP-seq
MIRT2510631	hsa-miR-362-3p	CLIP-seq
MIRT2510632	hsa-miR-3661	CLIP-seq
MIRT2510633	hsa-miR-3667-3p	CLIP-seq
MIRT916116	hsa-miR-377	CLIP-seq
MIRT2510634	hsa-miR-3913-3p	CLIP-seq
MIRT2510635	hsa-miR-3922-5p	CLIP-seq
MIRT2510638	hsa-miR-4269	CLIP-seq
MIRT2510639	hsa-miR-4276	CLIP-seq
MIRT2510640	hsa-miR-4284	CLIP-seq
MIRT916118	hsa-miR-4290	CLIP-seq
MIRT2510641	hsa-miR-4297	CLIP-seq
MIRT916120	hsa-miR-4325	CLIP-seq
MIRT916121	hsa-miR-4451	CLIP-seq
MIRT916122	hsa-miR-4459	CLIP-seq
MIRT2510642	hsa-miR-4467	CLIP-seq
MIRT916123	hsa-miR-4470	CLIP-seq
MIRT1971655	hsa-miR-4481	CLIP-seq
MIRT2510643	hsa-miR-4504	CLIP-seq
MIRT916124	hsa-miR-4530	CLIP-seq
MIRT2510644	hsa-miR-4645-3p	CLIP-seq
MIRT916128	hsa-miR-4687-5p	CLIP-seq
MIRT2510645	hsa-miR-4690-5p	CLIP-seq
MIRT2510646	hsa-miR-4701-3p	CLIP-seq
MIRT916143	hsa-miR-4711-5p	CLIP-seq
MIRT2510647	hsa-miR-4724-5p	CLIP-seq
MIRT1971656	hsa-miR-4745-5p	CLIP-seq
MIRT916129	hsa-miR-4751	CLIP-seq
MIRT2510648	hsa-miR-4763-3p	CLIP-seq
MIRT916130	hsa-miR-4770	CLIP-seq
MIRT916131	hsa-miR-4779	CLIP-seq
MIRT916132	hsa-miR-4783-3p	CLIP-seq
MIRT916133	hsa-miR-4793-3p	CLIP-seq
MIRT2510649	hsa-miR-486-3p	CLIP-seq
MIRT2510650	hsa-miR-498	CLIP-seq
MIRT2510651	hsa-miR-499-5p	CLIP-seq
MIRT1971657	hsa-miR-520a-5p	CLIP-seq
MIRT1971658	hsa-miR-525-5p	CLIP-seq
MIRT1971659	hsa-miR-548ac	CLIP-seq
MIRT1971660	hsa-miR-548d-3p	CLIP-seq
MIRT1971661	hsa-miR-548z	CLIP-seq
MIRT2510652	hsa-miR-593	CLIP-seq
MIRT2510653	hsa-miR-603	CLIP-seq
MIRT2510654	hsa-miR-606	CLIP-seq
MIRT2510655	hsa-miR-612	CLIP-seq
MIRT2510656	hsa-miR-631	CLIP-seq
MIRT2510657	hsa-miR-641	CLIP-seq
MIRT916135	hsa-miR-663	CLIP-seq
MIRT2510658	hsa-miR-663b	CLIP-seq
MIRT1971662	hsa-miR-744	CLIP-seq
MIRT2510659	hsa-miR-758	CLIP-seq
MIRT916136	hsa-miR-765	CLIP-seq
MIRT2510660	hsa-miR-876-5p	CLIP-seq
MIRT2510661	hsa-miR-922	CLIP-seq
MIRT916137	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001726	Component	Ruffle	IEA
GO:0001726	Component	Ruffle	ISS
GO:0002102	Component	Podosome	IEA
GO:0005515	Function	Protein binding	IPI	15169891, 15574754, 16636290, 17065230, 17255943, 18387954, 19146815, 19419567, 21220424, 21847094, 22252131, 22282019, 24574519, 24658140, 31980649, 32296183, 33961781
GO:0005522	Function	Profilin binding	IPI	24700464
GO:0005737	Component	Cytoplasm	IDA	10760273, 24700464
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005856	Component	Cytoskeleton	TAS	9054437
GO:0005884	Component	Actin filament	IDA	12151401
GO:0005884	Component	Actin filament	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005905	Component	Clathrin-coated pit	IEA
GO:0005905	Component	Clathrin-coated pit	ISS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IEA
GO:0005925	Component	Focal adhesion	IEA
GO:0005938	Component	Cell cortex	IDA	14742709, 24700464
GO:0005938	Component	Cell cortex	IEA
GO:0005938	Component	Cell cortex	ISS
GO:0006886	Process	Intracellular protein transport	IEA
GO:0006886	Process	Intracellular protein transport	IMP	17959782
GO:0006897	Process	Endocytosis	IEA
GO:0006898	Process	Receptor-mediated endocytosis	IEA
GO:0006898	Process	Receptor-mediated endocytosis	ISS
GO:0006930	Process	Substrate-dependent cell migration, cell extension	IEA
GO:0007165	Process	Signal transduction	IBA
GO:0008076	Component	Voltage-gated potassium channel complex	IDA	12151401
GO:0008076	Component	Voltage-gated potassium channel complex	IEA
GO:0016020	Component	Membrane	IEA
GO:0030027	Component	Lamellipodium	IDA	10760273, 12151401
GO:0030027	Component	Lamellipodium	IEA
GO:0030027	Component	Lamellipodium	ISS
GO:0030036	Process	Actin cytoskeleton organization	IEA
GO:0030036	Process	Actin cytoskeleton organization	ISS
GO:0030054	Component	Cell junction	IEA
GO:0030139	Component	Endocytic vesicle	IBA
GO:0030425	Component	Dendrite	IEA
GO:0030426	Component	Growth cone	IEA
GO:0030426	Component	Growth cone	ISS
GO:0030516	Process	Regulation of axon extension	IEA
GO:0030516	Process	Regulation of axon extension	ISS
GO:0030838	Process	Positive regulation of actin filament polymerization	IEA
GO:0030838	Process	Positive regulation of actin filament polymerization	IMP	24700464
GO:0030838	Process	Positive regulation of actin filament polymerization	ISS
GO:0030863	Component	Cortical cytoskeleton	IDA	12151401
GO:0042995	Component	Cell projection	IEA
GO:0043197	Component	Dendritic spine	IEA
GO:0045202	Component	Synapse	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045987	Process	Positive regulation of smooth muscle contraction	IMP	24700464
GO:0048041	Process	Focal adhesion assembly	IEA
GO:0048041	Process	Focal adhesion assembly	ISS
GO:0048812	Process	Neuron projection morphogenesis	IEA
GO:0048812	Process	Neuron projection morphogenesis	ISS
GO:0048870	Process	Cell motility	IEA
GO:0048870	Process	Cell motility	ISS
GO:0050921	Process	Positive regulation of chemotaxis	IEA
GO:0060491	Process	Regulation of cell projection assembly	IEA
GO:0070064	Function	Proline-rich region binding	IEA
GO:0070161	Component	Anchoring junction	IEA
GO:0071933	Function	Arp2/3 complex binding	IEA
GO:0097062	Process	Dendritic spine maintenance	IEA
GO:0097191	Process	Extrinsic apoptotic signaling pathway	IEA
GO:0097581	Process	Lamellipodium organization	IEA
GO:0097581	Process	Lamellipodium organization	ISS
GO:0098794	Component	Postsynapse	IEA
GO:0098871	Component	Postsynaptic actin cytoskeleton	IEA
GO:0098885	Process	Modification of postsynaptic actin cytoskeleton	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099010	Process	Modification of postsynaptic structure	IEA
GO:1901524	Process	Regulation of mitophagy	IEA
GO:1990023	Component	Mitotic spindle midzone	IEA
GO:2001237	Process	Negative regulation of extrinsic apoptotic signaling pathway	IEA

Other IDs

• MIM: 164765
• HGNC: 3338
• e!Ensembl: ENSG00000085733

Protein

• UniProt ID: Q14247
• Protein name: Src substrate cortactin (Amplaxin) (Oncogene EMS1)
• Protein function: Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of ne
• PDB: 1X69, 2D1X
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02218	HS1_rep	83 → 118	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	120 → 155	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	157 → 192	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	194 → 229	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	231 → 266	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	268 → 303	Repeat in HS1/Cortactin	Repeat
  PF02218	HS1_rep	305 → 332	Repeat in HS1/Cortactin	Repeat
  PF14604	SH3_9	499 → 547	Variant SH3 domain	Domain

• Sequence:

  MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRE
  NVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRG
  FGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
  KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQT
  DRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQ
  DYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKE
  KEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
  YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYP
  AEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
  FPANYVELRQ

• Sequence length: 550

Pathways

KEGG:

Tight junction
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Shigellosis
Proteoglycans in cancer

Reactome:

Clathrin-mediated endocytosis