CTTN (cortactin)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
2017 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Cortactin |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
CTTN |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
EMS1 |
|
Chromosome
Chromosome number
|
11 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
11q13.3 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | ||||||||||||||||||||||||||||||||||||||||||||||
| UniProt ID | Q14247 | |||||||||||||||||||||||||||||||||||||||||||||
| Protein name | Src substrate cortactin (Amplaxin) (Oncogene EMS1) | |||||||||||||||||||||||||||||||||||||||||||||
| Protein function | Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of ne | |||||||||||||||||||||||||||||||||||||||||||||
| PDB | 1X69 , 2D1X | |||||||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
|
|||||||||||||||||||||||||||||||||||||||||||||
| Sequence |
|
|||||||||||||||||||||||||||||||||||||||||||||
| Sequence length | 550 | |||||||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
|||||||||