Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	201475
Gene name Gene Name - the full gene name approved by the HGNC.	RAB12, member RAS oncogene family
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RAB12
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18p11.22

Show/Hide all(181)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020325	hsa-miR-130b-3p	Sequencing	20371350
MIRT021142	hsa-miR-186-5p	Sequencing	20371350
MIRT025992	hsa-miR-148a-3p	Sequencing	20371350
MIRT031886	hsa-miR-16-5p	Proteomics	18668040
MIRT053406	hsa-miR-629-5p	Microarray	23807165
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT080851	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT080848	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT080851	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT080847	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT080854	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT080849	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT080858	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT080848	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT025992	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT080878	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT080877	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT080876	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT1281609	hsa-miR-106a	CLIP-seq
MIRT1281610	hsa-miR-106b	CLIP-seq
MIRT1281611	hsa-miR-1197	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT1281613	hsa-miR-148a	CLIP-seq
MIRT1281614	hsa-miR-148b	CLIP-seq
MIRT1281615	hsa-miR-152	CLIP-seq
MIRT1281616	hsa-miR-153	CLIP-seq
MIRT1281617	hsa-miR-17	CLIP-seq
MIRT1281618	hsa-miR-186	CLIP-seq
MIRT1281619	hsa-miR-1912	CLIP-seq
MIRT1281620	hsa-miR-20a	CLIP-seq
MIRT1281621	hsa-miR-20b	CLIP-seq
MIRT1281622	hsa-miR-219-5p	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281624	hsa-miR-3130-5p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281627	hsa-miR-3200-3p	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281629	hsa-miR-345	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281632	hsa-miR-3659	CLIP-seq
MIRT1281633	hsa-miR-3662	CLIP-seq
MIRT1281634	hsa-miR-3671	CLIP-seq
MIRT1281635	hsa-miR-3676	CLIP-seq
MIRT1281636	hsa-miR-412	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281640	hsa-miR-4423-3p	CLIP-seq
MIRT1281641	hsa-miR-4445	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281643	hsa-miR-4482	CLIP-seq
MIRT1281644	hsa-miR-4668-3p	CLIP-seq
MIRT1281645	hsa-miR-4698	CLIP-seq
MIRT1281646	hsa-miR-4699-3p	CLIP-seq
MIRT1281647	hsa-miR-4724-3p	CLIP-seq
MIRT1281648	hsa-miR-4782-3p	CLIP-seq
MIRT1281649	hsa-miR-4797-5p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1281651	hsa-miR-503	CLIP-seq
MIRT1281652	hsa-miR-507	CLIP-seq
MIRT1281653	hsa-miR-508-3p	CLIP-seq
MIRT1281654	hsa-miR-519d	CLIP-seq
MIRT1281655	hsa-miR-520d-5p	CLIP-seq
MIRT1281656	hsa-miR-520g	CLIP-seq
MIRT1281657	hsa-miR-520h	CLIP-seq
MIRT1281658	hsa-miR-524-5p	CLIP-seq
MIRT1281659	hsa-miR-548m	CLIP-seq
MIRT1281660	hsa-miR-557	CLIP-seq
MIRT1281661	hsa-miR-586	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT1281663	hsa-miR-651	CLIP-seq
MIRT1281664	hsa-miR-759	CLIP-seq
MIRT1281665	hsa-miR-890	CLIP-seq
MIRT1281666	hsa-miR-93	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT1281611	hsa-miR-1197	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281634	hsa-miR-3671	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT2083254	hsa-miR-4282	CLIP-seq
MIRT2083255	hsa-miR-4662a-3p	CLIP-seq
MIRT1920843	hsa-miR-4719	CLIP-seq
MIRT1920844	hsa-miR-4760-3p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1920845	hsa-miR-513b	CLIP-seq
MIRT2083256	hsa-miR-567	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT1281663	hsa-miR-651	CLIP-seq
MIRT2308599	hsa-miR-1279	CLIP-seq
MIRT2308600	hsa-miR-130a	CLIP-seq
MIRT2308601	hsa-miR-130b	CLIP-seq
MIRT2308602	hsa-miR-1323	CLIP-seq
MIRT1281612	hsa-miR-140-3p	CLIP-seq
MIRT2308603	hsa-miR-142-3p	CLIP-seq
MIRT1281616	hsa-miR-153	CLIP-seq
MIRT1281619	hsa-miR-1912	CLIP-seq
MIRT2308604	hsa-miR-199a-5p	CLIP-seq
MIRT2308605	hsa-miR-199b-5p	CLIP-seq
MIRT1281622	hsa-miR-219-5p	CLIP-seq
MIRT2308606	hsa-miR-297	CLIP-seq
MIRT2308607	hsa-miR-298	CLIP-seq
MIRT2308608	hsa-miR-301a	CLIP-seq
MIRT2308609	hsa-miR-301b	CLIP-seq
MIRT1281623	hsa-miR-3117-3p	CLIP-seq
MIRT1281624	hsa-miR-3130-5p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281628	hsa-miR-329	CLIP-seq
MIRT1281630	hsa-miR-3591-5p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281631	hsa-miR-362-3p	CLIP-seq
MIRT1281633	hsa-miR-3662	CLIP-seq
MIRT2308610	hsa-miR-3666	CLIP-seq
MIRT2308611	hsa-miR-3691-3p	CLIP-seq
MIRT2308612	hsa-miR-3923	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281638	hsa-miR-4280	CLIP-seq
MIRT2308613	hsa-miR-4295	CLIP-seq
MIRT2308614	hsa-miR-4305	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281641	hsa-miR-4445	CLIP-seq
MIRT2308615	hsa-miR-4464	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281643	hsa-miR-4482	CLIP-seq
MIRT2308616	hsa-miR-454	CLIP-seq
MIRT2308617	hsa-miR-4671-3p	CLIP-seq
MIRT1281645	hsa-miR-4698	CLIP-seq
MIRT2308618	hsa-miR-4704-5p	CLIP-seq
MIRT2308619	hsa-miR-4748	CLIP-seq
MIRT2308620	hsa-miR-4762-5p	CLIP-seq
MIRT2308621	hsa-miR-4778-5p	CLIP-seq
MIRT1281648	hsa-miR-4782-3p	CLIP-seq
MIRT1281650	hsa-miR-485-3p	CLIP-seq
MIRT1281653	hsa-miR-508-3p	CLIP-seq
MIRT2308622	hsa-miR-548o	CLIP-seq
MIRT2083256	hsa-miR-567	CLIP-seq
MIRT1281662	hsa-miR-607	CLIP-seq
MIRT2308623	hsa-miR-628-3p	CLIP-seq
MIRT2308624	hsa-miR-663b	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281642	hsa-miR-448	CLIP-seq
MIRT1281646	hsa-miR-4699-3p	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT1281626	hsa-miR-3140-3p	CLIP-seq
MIRT1281637	hsa-miR-4272	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq
MIRT2083254	hsa-miR-4282	CLIP-seq
MIRT1281639	hsa-miR-4325	CLIP-seq
MIRT1281652	hsa-miR-507	CLIP-seq
MIRT1281660	hsa-miR-557	CLIP-seq
MIRT2457585	hsa-miR-590-3p	CLIP-seq
MIRT1281625	hsa-miR-3133	CLIP-seq
MIRT739006	hsa-miR-3613-3p	CLIP-seq

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	26824392
GO:0005525	Function	GTP binding	IEA
GO:0005764	Component	Lysosome	ISS
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005768	Component	Endosome	IBA	21873635
GO:0005776	Component	Autophagosome	IEA
GO:0005794	Component	Golgi apparatus	IBA	21873635
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006904	Process	Vesicle docking involved in exocytosis	IBA	21873635
GO:0006914	Process	Autophagy	IEA
GO:0008021	Component	Synaptic vesicle	IBA	21873635
GO:0008333	Process	Endosome to lysosome transport	ISS
GO:0009306	Process	Protein secretion	IBA	21873635
GO:0017157	Process	Regulation of exocytosis	IBA	21873635
GO:0019003	Function	GDP binding	IDA	20937701
GO:0032482	Process	Rab protein signal transduction	IEA
GO:0032593	Component	Insulin-responsive compartment	IBA	21873635
GO:0032869	Process	Cellular response to insulin stimulus	IBA	21873635
GO:0044257	Process	Cellular protein catabolic process	ISS
GO:0055037	Component	Recycling endosome	IBA	21873635
GO:0055038	Component	Recycling endosome membrane	ISS
GO:0055038	Component	Recycling endosome membrane	TAS
GO:0072659	Process	Protein localization to plasma membrane	IBA	21873635

MIM	HGNC	e!Ensembl
616448	31332	ENSG00000206418

Protein

UniProt ID

Q6IQ22

Protein name

Ras-related protein Rab-12 (EC 3.6.5.2)

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r

PDB

2IL1 , 8VH4 , 8VH5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	44 → 206	Ras family	Domain

Sequence

MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLME
RFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIIL
VYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGM
RFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPH
VRCC

Sequence length

244

Interactions

View interactions

	Reactome
			RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.	GWAS, CBGDA
Oligodendroglioma	Oligodendroglioma		GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Parkinson Disease	Associate	39705401

RAB12 (RAB12, member RAS oncogene family)