Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
201266
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 39 member 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC39A11
Synonyms (NCBI Gene) Gene synonyms aliases
C17orf26, ZIP-11, ZIP11
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q24.3-q25.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019384 hsa-miR-148b-3p Microarray 17612493
MIRT019808 hsa-miR-375 Microarray 20215506
MIRT021987 hsa-miR-128-3p Microarray 17612493
MIRT022609 hsa-miR-124-3p Microarray 18668037
MIRT025772 hsa-miR-7-5p Microarray 17612493
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005375 Function Copper ion transmembrane transporter activity IEA
GO:0005375 Function Copper ion transmembrane transporter activity ISS
GO:0005385 Function Zinc ion transmembrane transporter activity IBA
GO:0005385 Function Zinc ion transmembrane transporter activity IEA
GO:0005385 Function Zinc ion transmembrane transporter activity ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616508 14463 ENSG00000133195
Protein
UniProt ID Q8N1S5
Protein name Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11)
Protein function Zinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus. May transport copper ions as well. The transport mechanism rema
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02535 Zip 7 338 ZIP Zinc transporter Family
Sequence
Sequence length 342
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Alzheimer disease
Parkinson disease
 
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Alzheimer disease Alzheimer's disease or family history of Alzheimer's disease N/A N/A GWAS
Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosis N/A N/A GWAS
Breast Cancer BRCA1/2-negative high-risk breast cancer N/A N/A GWAS
Crohn Disease Crohn's disease N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 32744318, 35739271, 38259456
Carcinoma Ovarian Epithelial Associate 26091520
Carcinoma Renal Cell Associate 25900876
Glioma Associate 25921144
Inflammatory Bowel Diseases Associate 36155972
Neoplasms Associate 25900876
Neoplasms Inhibit 25921144
Urinary Bladder Neoplasms Associate 25900876