Gene Gene information from NCBI Gene database.
Entrez ID 201266
Gene name Solute carrier family 39 member 11
Gene symbol SLC39A11
Synonyms (NCBI Gene)
C17orf26ZIP-11ZIP11
Chromosome 17
Chromosome location 17q24.3-q25.1
miRNA miRNA information provided by mirtarbase database.
218
miRTarBase ID miRNA Experiments Reference
MIRT019384 hsa-miR-148b-3p Microarray 17612493
MIRT019808 hsa-miR-375 Microarray 20215506
MIRT021987 hsa-miR-128-3p Microarray 17612493
MIRT022609 hsa-miR-124-3p Microarray 18668037
MIRT025772 hsa-miR-7-5p Microarray 17612493
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0005375 Function Copper ion transmembrane transporter activity IEA
GO:0005375 Function Copper ion transmembrane transporter activity ISS
GO:0005385 Function Zinc ion transmembrane transporter activity IBA
GO:0005385 Function Zinc ion transmembrane transporter activity IEA
GO:0005385 Function Zinc ion transmembrane transporter activity ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616508 14463 ENSG00000133195
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N1S5
Protein name Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11)
Protein function Zinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus. May transport copper ions as well. The transport mechanism rema
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02535 Zip 7 338 ZIP Zinc transporter Family
Sequence
Sequence length 342
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Alzheimer disease
Parkinson disease
 
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
8
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Cervical cancer Benign rs78761885 RCV005903743
Clear cell carcinoma of kidney Benign rs78761885 RCV005903744
Colon adenocarcinoma Benign rs78761885 RCV005903741
Ependymoma Uncertain significance rs745762301 RCV000577870
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 32744318, 35739271, 38259456
Carcinoma Ovarian Epithelial Associate 26091520
Carcinoma Renal Cell Associate 25900876
Glioma Associate 25921144
Inflammatory Bowel Diseases Associate 36155972
Neoplasms Associate 25900876
Neoplasms Inhibit 25921144
Urinary Bladder Neoplasms Associate 25900876