Gene Gene information from NCBI Gene database.
Entrez ID 200933
Gene name F-box protein 45
Gene symbol FBXO45
Synonyms (NCBI Gene)
Fbx45
Chromosome 3
Chromosome location 3q29
Summary Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box pr
miRNA miRNA information provided by mirtarbase database.
883
miRTarBase ID miRNA Experiments Reference
MIRT023967 hsa-miR-1-3p Microarray 18668037
MIRT049278 hsa-miR-92a-3p CLASH 23622248
MIRT039138 hsa-miR-769-5p CLASH 23622248
MIRT703623 hsa-miR-3974 HITS-CLIP 23313552
MIRT703622 hsa-miR-624-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
46
GO ID Ontology Definition Evidence Reference
GO:0001764 Process Neuron migration IEA
GO:0005515 Function Protein binding IPI 19581926
GO:0005576 Component Extracellular region IEA
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609112 29148 ENSG00000174013
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P0C2W1
Protein name F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)
Protein function Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1 (PubMed:29997255). Functions in substrate recognition but also plays an important role in assembly of the complex (PubMed:29997255). Required for normal neuromuscular
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like 37 85 F-box-like Domain
PF00622 SPRY 154 281 SPRY domain Family
Sequence
Sequence length 286
Interactions View interactions