Gene Gene information from NCBI Gene database.
Entrez ID 200407
Gene name Cellular repressor of E1A stimulated genes 2
Gene symbol CREG2
Synonyms (NCBI Gene)
-
Chromosome 2
Chromosome location 2q11.2
miRNA miRNA information provided by mirtarbase database.
134
miRTarBase ID miRNA Experiments Reference
MIRT615787 hsa-miR-548e-5p HITS-CLIP 23824327
MIRT668899 hsa-miR-3606-3p HITS-CLIP 23824327
MIRT668898 hsa-miR-513a-3p HITS-CLIP 23824327
MIRT668897 hsa-miR-513c-3p HITS-CLIP 23824327
MIRT668896 hsa-miR-205-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005576 Component Extracellular region IEA
GO:0005615 Component Extracellular space IBA
GO:0005737 Component Cytoplasm IEA
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005794 Component Golgi apparatus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618540 14272 ENSG00000175874
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IUH2
Protein name Protein CREG2 (Cellular repressor of E1A-stimulated genes 2)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13883 Pyrid_oxidase_2 118 284 Domain
Tissue specificity TISSUE SPECIFICITY: Brain specific mainly in the limbic system and faintly in the spinal cord but not in cerebellum. {ECO:0000269|PubMed:12408961}.
Sequence
MSVRRGRRPARPGTRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEAMP
ALLEDSGSIWQQSFPASAHKEDAHLRPRAGAARARPPPAPPGMFSYRREGGQTASAPPGP
RLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDP
VVADLMKNPMASLMLPESEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMF
SRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSISREEYFK
AVPRKA
Sequence length 290
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
MENTAL OR BEHAVIOURAL DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PSYCHOSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations