APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A)

Gene

• Entrez ID: 200315
• Gene name: Apolipoprotein B mRNA editing enzyme catalytic subunit 3A
• Gene symbol: APOBEC3A
• Synonyms (NCBI Gene): A3A, ARP3, PHRBN, bK150C2.1
• Chromosome: 22
• Chromosome location: 22q13.1
• Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and fu

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT679809	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT679808	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT679807	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679806	hsa-miR-1976	HITS-CLIP	23824327
MIRT679805	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679804	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679803	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT679802	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT679801	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679800	hsa-miR-640	HITS-CLIP	23824327
MIRT679799	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT679798	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679797	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT731448	hsa-let-7a-3p	Luciferase reporter assay	26991540
MIRT731448	hsa-let-7a-3p	Luciferase reporter assay	26991540
MIRT679809	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT679808	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT679807	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679806	hsa-miR-1976	HITS-CLIP	23824327
MIRT679805	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679804	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679803	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT679802	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT679801	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679800	hsa-miR-640	HITS-CLIP	23824327
MIRT679799	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT679798	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679797	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT789809	hsa-miR-129-5p	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT789811	hsa-miR-3149	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT789813	hsa-miR-3199	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789817	hsa-miR-4474-5p	CLIP-seq
MIRT789818	hsa-miR-4532	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789822	hsa-miR-4722-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789825	hsa-miR-4777-5p	CLIP-seq
MIRT789826	hsa-miR-4786-3p	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789830	hsa-miR-520a-5p	CLIP-seq
MIRT789831	hsa-miR-525-5p	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT789834	hsa-miR-599	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT1932949	hsa-miR-106a	CLIP-seq
MIRT1932950	hsa-miR-106b	CLIP-seq
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT1932951	hsa-miR-122	CLIP-seq
MIRT1932952	hsa-miR-1307	CLIP-seq
MIRT1932953	hsa-miR-17	CLIP-seq
MIRT1932954	hsa-miR-20a	CLIP-seq
MIRT1932955	hsa-miR-20b	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT1932956	hsa-miR-302a	CLIP-seq
MIRT1932957	hsa-miR-302b	CLIP-seq
MIRT1932958	hsa-miR-302c	CLIP-seq
MIRT1932959	hsa-miR-302d	CLIP-seq
MIRT1932960	hsa-miR-302e	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT1932961	hsa-miR-3194-3p	CLIP-seq
MIRT789813	hsa-miR-3199	CLIP-seq
MIRT1932962	hsa-miR-372	CLIP-seq
MIRT1932963	hsa-miR-373	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT1932964	hsa-miR-4284	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789822	hsa-miR-4722-3p	CLIP-seq
MIRT1932965	hsa-miR-4731-5p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT1932966	hsa-miR-512-3p	CLIP-seq
MIRT1932967	hsa-miR-519d	CLIP-seq
MIRT1932968	hsa-miR-520a-3p	CLIP-seq
MIRT789830	hsa-miR-520a-5p	CLIP-seq
MIRT1932969	hsa-miR-520b	CLIP-seq
MIRT1932970	hsa-miR-520c-3p	CLIP-seq
MIRT1932971	hsa-miR-520d-3p	CLIP-seq
MIRT1932972	hsa-miR-520e	CLIP-seq
MIRT1932973	hsa-miR-520g	CLIP-seq
MIRT1932974	hsa-miR-520h	CLIP-seq
MIRT789831	hsa-miR-525-5p	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT1932975	hsa-miR-93	CLIP-seq
MIRT1932949	hsa-miR-106a	CLIP-seq
MIRT1932950	hsa-miR-106b	CLIP-seq
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT1932951	hsa-miR-122	CLIP-seq
MIRT1932952	hsa-miR-1307	CLIP-seq
MIRT1932953	hsa-miR-17	CLIP-seq
MIRT1932954	hsa-miR-20a	CLIP-seq
MIRT1932955	hsa-miR-20b	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT1932956	hsa-miR-302a	CLIP-seq
MIRT1932957	hsa-miR-302b	CLIP-seq
MIRT1932958	hsa-miR-302c	CLIP-seq
MIRT1932959	hsa-miR-302d	CLIP-seq
MIRT1932960	hsa-miR-302e	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT1932961	hsa-miR-3194-3p	CLIP-seq
MIRT1932962	hsa-miR-372	CLIP-seq
MIRT1932963	hsa-miR-373	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT1932964	hsa-miR-4284	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789818	hsa-miR-4532	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT1932965	hsa-miR-4731-5p	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT1932966	hsa-miR-512-3p	CLIP-seq
MIRT1932967	hsa-miR-519d	CLIP-seq
MIRT1932968	hsa-miR-520a-3p	CLIP-seq
MIRT1932969	hsa-miR-520b	CLIP-seq
MIRT1932970	hsa-miR-520c-3p	CLIP-seq
MIRT1932971	hsa-miR-520d-3p	CLIP-seq
MIRT1932972	hsa-miR-520e	CLIP-seq
MIRT1932973	hsa-miR-520g	CLIP-seq
MIRT1932974	hsa-miR-520h	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT1932975	hsa-miR-93	CLIP-seq
MIRT789809	hsa-miR-129-5p	CLIP-seq
MIRT789811	hsa-miR-3149	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT789809	hsa-miR-129-5p	CLIP-seq
MIRT789811	hsa-miR-3149	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT789808	hsa-miR-1193	CLIP-seq
MIRT1932951	hsa-miR-122	CLIP-seq
MIRT789809	hsa-miR-129-5p	CLIP-seq
MIRT789810	hsa-miR-2392	CLIP-seq
MIRT789811	hsa-miR-3149	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT789813	hsa-miR-3199	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq
MIRT789809	hsa-miR-129-5p	CLIP-seq
MIRT789811	hsa-miR-3149	CLIP-seq
MIRT789812	hsa-miR-3152-3p	CLIP-seq
MIRT789813	hsa-miR-3199	CLIP-seq
MIRT789814	hsa-miR-411	CLIP-seq
MIRT789815	hsa-miR-4258	CLIP-seq
MIRT789816	hsa-miR-4438	CLIP-seq
MIRT789819	hsa-miR-4662a-5p	CLIP-seq
MIRT789820	hsa-miR-4676-5p	CLIP-seq
MIRT789821	hsa-miR-4707-3p	CLIP-seq
MIRT789823	hsa-miR-4735-5p	CLIP-seq
MIRT789824	hsa-miR-4775	CLIP-seq
MIRT789827	hsa-miR-4794	CLIP-seq
MIRT789828	hsa-miR-5095	CLIP-seq
MIRT789829	hsa-miR-5096	CLIP-seq
MIRT789832	hsa-miR-575	CLIP-seq
MIRT789833	hsa-miR-590-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IBA
GO:0002376	Process	Immune system process	IEA
GO:0003723	Function	RNA binding	IBA
GO:0003824	Function	Catalytic activity	IEA
GO:0004126	Function	Cytidine deaminase activity	IBA
GO:0004126	Function	Cytidine deaminase activity	IDA	16527742, 21123384
GO:0004126	Function	Cytidine deaminase activity	IEA
GO:0004126	Function	Cytidine deaminase activity	IMP	20062055, 22457529
GO:0005515	Function	Protein binding	IPI	22915799, 24557838, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	16527742, 21123384, 21835787
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	16527742, 21123384, 21835787
GO:0005737	Component	Cytoplasm	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010526	Process	Transposable element silencing	IDA	16527742, 21123384
GO:0010526	Process	Transposable element silencing	IEA
GO:0016554	Process	Cytidine to uridine editing	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0044029	Process	Positive regulation of gene expression via chromosomal CpG island demethylation	IDA	21496894
GO:0044355	Process	Clearance of foreign intracellular DNA	IDA	20062055
GO:0044355	Process	Clearance of foreign intracellular DNA	IEA
GO:0045071	Process	Negative regulation of viral genome replication	IDA	16527742
GO:0045071	Process	Negative regulation of viral genome replication	IEA
GO:0045087	Process	Innate immune response	IDA	21123384
GO:0045087	Process	Innate immune response	IEA
GO:0045869	Process	Negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0051607	Process	Defense response to virus	IBA
GO:0051607	Process	Defense response to virus	IDA	21123384, 22457529
GO:0051607	Process	Defense response to virus	IEA
GO:0070383	Process	DNA cytosine deamination	IBA

Other IDs

• MIM: 607109
• HGNC: 17343
• e!Ensembl: ENSG00000128383

Interactions View interactions

Pathways

KEGG:

Viral life cycle - HIV-1
Human immunodeficiency virus 1 infection

Reactome:

mRNA Editing: C to U Conversion
Formation of the Editosome