NUDT17 (nudix hydrolase 17)

Gene
Gene Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
200035
Gene name Gene Name - the full gene name approved by the HGNC.
Nudix hydrolase 17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NUDT17
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q21.1
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein
Show/Hide all(10)
GO ID Ontology Definition Evidence Reference
GO:0005777 Component Peroxisome IBA
GO:0006742 Process NADP+ catabolic process IBA
GO:0016787 Function Hydrolase activity IEA
GO:0019674 Process NAD+ metabolic process IBA
GO:0019677 Process NAD+ catabolic process IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene Gene ontology Other IDs Protein
UniProt ID P0C025
Protein name m7GpppN-mRNA hydrolase NUDT17 (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 17) (Nudix motif 17)
Protein function Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA. {ECO:00002
PDB 5LF8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00293 NUDIX 90 → 234 NUDIX domain Domain
Sequence 
MAEVRVQLLLSRRPESVSFARSVCGLLGAGPGLGTWPIHCSLKRGRLVLSSRPFPGASAR
LPLQRPPFCPFAALEERPRVPGAELPTDRGVDLGVAVILQSSDKTVLLTRRARTLSVSPN
LWVPPGGHVELEEELLDGGLRELWEESGLHLPQGQFSWVPLGLWESAYPPRLSWGLPKYH
HIVLYLLVISQESQQQLQARIQPNPNEVSALMWLTPDVAAAVAAAEDGTETPGLLPQDLP
PSVLAVELEEDGRARPLVLHMSTLLRMIPTMAEDKERVSTGTKFALKLWLQHLGRTPPPC
KSAAYLDPGPAKEEWNMDPLPPNQGSGK
Sequence length 328
Interactions View interactions
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