Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1974
Gene name	Eukaryotic translation initiation factor 4A2
Gene symbol	EIF4A2
Synonyms (NCBI Gene)	BM-010DDX2BEIF4AEIF4FNEDHSSeIF-4A-IIeIF4A-II
Chromosome	3
Chromosome location	3q27.3

541

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005772	hsa-miR-21-5p	ImmunoblotImmunohistochemistryLuciferase reporter assayMicroarrayqRT-PCRWestern blot	21219636
MIRT005772	hsa-miR-21-5p	ImmunoblotImmunohistochemistryLuciferase reporter assayMicroarrayqRT-PCRWestern blot	21219636
MIRT032347	hsa-let-7b-5p	Proteomics	18668040
MIRT043428	hsa-miR-331-3p	CLASH	23622248
MIRT037614	hsa-miR-744-5p	CLASH	23622248
MIRT507446	hsa-miR-183-5p	HITS-CLIP	21572407
MIRT209478	hsa-miR-19b-3p	HITS-CLIP	21572407
MIRT209477	hsa-miR-19a-3p	HITS-CLIP	21572407
MIRT507445	hsa-miR-499a-5p	HITS-CLIP	21572407
MIRT507444	hsa-miR-208a-3p	HITS-CLIP	21572407
MIRT507443	hsa-miR-208b-3p	HITS-CLIP	21572407
MIRT708146	hsa-miR-6771-3p	HITS-CLIP	21572407
MIRT209481	hsa-miR-3617-5p	HITS-CLIP	21572407
MIRT209480	hsa-miR-641	HITS-CLIP	21572407
MIRT209482	hsa-miR-5583-3p	HITS-CLIP	21572407
MIRT209479	hsa-miR-590-3p	HITS-CLIP	21572407
MIRT567697	hsa-miR-4667-5p	HITS-CLIP	21572407
MIRT567696	hsa-miR-4700-5p	HITS-CLIP	21572407
MIRT567695	hsa-miR-8089	HITS-CLIP	21572407
MIRT567694	hsa-miR-4450	HITS-CLIP	21572407
MIRT567693	hsa-miR-6857-5p	HITS-CLIP	21572407
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT209479	hsa-miR-590-3p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	20371350
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	20371350
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT209479	hsa-miR-590-3p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	20371350
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	20371350
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT567697	hsa-miR-4667-5p	PAR-CLIP	20371350
MIRT567696	hsa-miR-4700-5p	PAR-CLIP	20371350
MIRT567695	hsa-miR-8089	PAR-CLIP	20371350
MIRT567694	hsa-miR-4450	PAR-CLIP	20371350
MIRT567693	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT091386	hsa-miR-543	PAR-CLIP	20371350
MIRT091389	hsa-miR-3609	PAR-CLIP	20371350
MIRT091390	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT567692	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT567691	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT567690	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT567689	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT567688	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT567687	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT567686	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT567685	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT567684	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT091394	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT091385	hsa-miR-300	PAR-CLIP	20371350
MIRT091383	hsa-miR-381-3p	PAR-CLIP	20371350
MIRT091391	hsa-miR-4666a-3p	PAR-CLIP	20371350
MIRT091387	hsa-miR-3143	PAR-CLIP	20371350
MIRT091374	hsa-let-7a-3p	PAR-CLIP	20371350
MIRT091375	hsa-let-7b-3p	PAR-CLIP	20371350
MIRT091376	hsa-let-7f-1-3p	PAR-CLIP	20371350
MIRT091378	hsa-miR-98-3p	PAR-CLIP	20371350
MIRT091382	hsa-miR-302c-5p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT209480	hsa-miR-641	PAR-CLIP	21572407
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT209479	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT507446	hsa-miR-183-5p	PAR-CLIP	22012620
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	22012620
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	22012620
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	22012620
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	22012620
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	22012620
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT209480	hsa-miR-641	PAR-CLIP	22012620
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	22012620
MIRT209479	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	23446348
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	23446348
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	23446348
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	23446348
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT440737	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440737	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT507446	hsa-miR-183-5p	HITS-CLIP	21572407
MIRT209478	hsa-miR-19b-3p	HITS-CLIP	21572407
MIRT209477	hsa-miR-19a-3p	HITS-CLIP	21572407
MIRT507445	hsa-miR-499a-5p	HITS-CLIP	21572407
MIRT507444	hsa-miR-208a-3p	HITS-CLIP	21572407
MIRT507443	hsa-miR-208b-3p	HITS-CLIP	21572407
MIRT708146	hsa-miR-6771-3p	HITS-CLIP	21572407
MIRT209481	hsa-miR-3617-5p	HITS-CLIP	21572407
MIRT209480	hsa-miR-641	HITS-CLIP	21572407
MIRT209482	hsa-miR-5583-3p	HITS-CLIP	21572407
MIRT209479	hsa-miR-590-3p	HITS-CLIP	21572407
MIRT567697	hsa-miR-4667-5p	HITS-CLIP	21572407
MIRT567696	hsa-miR-4700-5p	HITS-CLIP	21572407
MIRT567695	hsa-miR-8089	HITS-CLIP	21572407
MIRT567694	hsa-miR-4450	HITS-CLIP	21572407
MIRT567693	hsa-miR-6857-5p	HITS-CLIP	21572407
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT209479	hsa-miR-590-3p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	20371350
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	20371350
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT209479	hsa-miR-590-3p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	20371350
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	20371350
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	20371350
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	20371350
MIRT209480	hsa-miR-641	PAR-CLIP	20371350
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT567697	hsa-miR-4667-5p	PAR-CLIP	20371350
MIRT567696	hsa-miR-4700-5p	PAR-CLIP	20371350
MIRT567695	hsa-miR-8089	PAR-CLIP	20371350
MIRT567694	hsa-miR-4450	PAR-CLIP	20371350
MIRT567693	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT091386	hsa-miR-543	PAR-CLIP	20371350
MIRT091389	hsa-miR-3609	PAR-CLIP	20371350
MIRT091390	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT567692	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT567691	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT567690	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT567689	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT567688	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT567687	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT567686	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT567685	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT567684	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT091394	hsa-miR-7849-3p	PAR-CLIP	20371350
MIRT091385	hsa-miR-300	PAR-CLIP	20371350
MIRT091383	hsa-miR-381-3p	PAR-CLIP	20371350
MIRT091391	hsa-miR-4666a-3p	PAR-CLIP	20371350
MIRT091387	hsa-miR-3143	PAR-CLIP	20371350
MIRT091374	hsa-let-7a-3p	PAR-CLIP	20371350
MIRT091375	hsa-let-7b-3p	PAR-CLIP	20371350
MIRT091376	hsa-let-7f-1-3p	PAR-CLIP	20371350
MIRT091378	hsa-miR-98-3p	PAR-CLIP	20371350
MIRT091382	hsa-miR-302c-5p	PAR-CLIP	20371350
MIRT507446	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	21572407
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	21572407
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	21572407
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	21572407
MIRT209480	hsa-miR-641	PAR-CLIP	21572407
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT209479	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT507446	hsa-miR-183-5p	PAR-CLIP	22012620
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	22012620
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	22012620
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	22012620
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	22012620
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	22012620
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	22012620
MIRT209480	hsa-miR-641	PAR-CLIP	22012620
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	22012620
MIRT209479	hsa-miR-590-3p	PAR-CLIP	22012620
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	23446348
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	23446348
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT507446	hsa-miR-183-5p	PAR-CLIP	23446348
MIRT209478	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT209477	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT507445	hsa-miR-499a-5p	PAR-CLIP	23446348
MIRT507444	hsa-miR-208a-3p	PAR-CLIP	23446348
MIRT507443	hsa-miR-208b-3p	PAR-CLIP	23446348
MIRT209481	hsa-miR-3617-5p	PAR-CLIP	23446348
MIRT209480	hsa-miR-641	PAR-CLIP	23446348
MIRT209482	hsa-miR-5583-3p	PAR-CLIP	23446348
MIRT209479	hsa-miR-590-3p	PAR-CLIP	23446348
MIRT957805	hsa-miR-1273e	CLIP-seq
MIRT957806	hsa-miR-139-5p	CLIP-seq
MIRT957807	hsa-miR-145	CLIP-seq
MIRT957808	hsa-miR-181a	CLIP-seq
MIRT957809	hsa-miR-181b	CLIP-seq
MIRT957810	hsa-miR-181c	CLIP-seq
MIRT957811	hsa-miR-181d	CLIP-seq
MIRT957812	hsa-miR-183	CLIP-seq
MIRT957813	hsa-miR-19a	CLIP-seq
MIRT957814	hsa-miR-19b	CLIP-seq
MIRT957815	hsa-miR-208a	CLIP-seq
MIRT957816	hsa-miR-208b	CLIP-seq
MIRT957817	hsa-miR-3120-3p	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT957819	hsa-miR-3155	CLIP-seq
MIRT957820	hsa-miR-3155b	CLIP-seq
MIRT957821	hsa-miR-3159	CLIP-seq
MIRT957822	hsa-miR-3617	CLIP-seq
MIRT957823	hsa-miR-3646	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957825	hsa-miR-377	CLIP-seq
MIRT957826	hsa-miR-381	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT957828	hsa-miR-3976	CLIP-seq
MIRT957829	hsa-miR-4262	CLIP-seq
MIRT957830	hsa-miR-4283	CLIP-seq
MIRT957831	hsa-miR-4327	CLIP-seq
MIRT957832	hsa-miR-4477a	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT957833	hsa-miR-4489	CLIP-seq
MIRT957834	hsa-miR-4540	CLIP-seq
MIRT957835	hsa-miR-4666-3p	CLIP-seq
MIRT957836	hsa-miR-4731-5p	CLIP-seq
MIRT957837	hsa-miR-4766-3p	CLIP-seq
MIRT957838	hsa-miR-4789-5p	CLIP-seq
MIRT957839	hsa-miR-4795-3p	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT957840	hsa-miR-484	CLIP-seq
MIRT957841	hsa-miR-499-5p	CLIP-seq
MIRT957842	hsa-miR-510	CLIP-seq
MIRT957843	hsa-miR-512-5p	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT957845	hsa-miR-656	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT957806	hsa-miR-139-5p	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT1556271	hsa-miR-3671	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT1556272	hsa-miR-4496	CLIP-seq
MIRT1556273	hsa-miR-607	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT1983721	hsa-miR-1323	CLIP-seq
MIRT957807	hsa-miR-145	CLIP-seq
MIRT957812	hsa-miR-183	CLIP-seq
MIRT957813	hsa-miR-19a	CLIP-seq
MIRT957814	hsa-miR-19b	CLIP-seq
MIRT957815	hsa-miR-208a	CLIP-seq
MIRT957816	hsa-miR-208b	CLIP-seq
MIRT1983722	hsa-miR-217	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT1983723	hsa-miR-324-5p	CLIP-seq
MIRT957822	hsa-miR-3617	CLIP-seq
MIRT957823	hsa-miR-3646	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957825	hsa-miR-377	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT957828	hsa-miR-3976	CLIP-seq
MIRT1983724	hsa-miR-4291	CLIP-seq
MIRT957832	hsa-miR-4477a	CLIP-seq
MIRT957834	hsa-miR-4540	CLIP-seq
MIRT957839	hsa-miR-4795-3p	CLIP-seq
MIRT957841	hsa-miR-499-5p	CLIP-seq
MIRT1983725	hsa-miR-545	CLIP-seq
MIRT1983726	hsa-miR-548o	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT957845	hsa-miR-656	CLIP-seq
MIRT2219024	hsa-miR-1185	CLIP-seq
MIRT957805	hsa-miR-1273e	CLIP-seq
MIRT2219025	hsa-miR-1276	CLIP-seq
MIRT2219026	hsa-miR-132	CLIP-seq
MIRT1983721	hsa-miR-1323	CLIP-seq
MIRT957807	hsa-miR-145	CLIP-seq
MIRT957808	hsa-miR-181a	CLIP-seq
MIRT957809	hsa-miR-181b	CLIP-seq
MIRT957810	hsa-miR-181c	CLIP-seq
MIRT957811	hsa-miR-181d	CLIP-seq
MIRT957812	hsa-miR-183	CLIP-seq
MIRT957813	hsa-miR-19a	CLIP-seq
MIRT957814	hsa-miR-19b	CLIP-seq
MIRT957815	hsa-miR-208a	CLIP-seq
MIRT957816	hsa-miR-208b	CLIP-seq
MIRT2219027	hsa-miR-212	CLIP-seq
MIRT1983722	hsa-miR-217	CLIP-seq
MIRT957817	hsa-miR-3120-3p	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT957819	hsa-miR-3155	CLIP-seq
MIRT957820	hsa-miR-3155b	CLIP-seq
MIRT957821	hsa-miR-3159	CLIP-seq
MIRT2219028	hsa-miR-3160-5p	CLIP-seq
MIRT2219029	hsa-miR-3162-3p	CLIP-seq
MIRT1983723	hsa-miR-324-5p	CLIP-seq
MIRT2219030	hsa-miR-338-5p	CLIP-seq
MIRT957822	hsa-miR-3617	CLIP-seq
MIRT1556271	hsa-miR-3671	CLIP-seq
MIRT2219031	hsa-miR-3672	CLIP-seq
MIRT2219032	hsa-miR-3679-5p	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957825	hsa-miR-377	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT2219033	hsa-miR-3938	CLIP-seq
MIRT957828	hsa-miR-3976	CLIP-seq
MIRT957829	hsa-miR-4262	CLIP-seq
MIRT957830	hsa-miR-4283	CLIP-seq
MIRT1983724	hsa-miR-4291	CLIP-seq
MIRT2219034	hsa-miR-4311	CLIP-seq
MIRT2219035	hsa-miR-4315	CLIP-seq
MIRT957831	hsa-miR-4327	CLIP-seq
MIRT2219036	hsa-miR-4454	CLIP-seq
MIRT2219037	hsa-miR-4461	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT957833	hsa-miR-4489	CLIP-seq
MIRT2219038	hsa-miR-4509	CLIP-seq
MIRT957834	hsa-miR-4540	CLIP-seq
MIRT957835	hsa-miR-4666-3p	CLIP-seq
MIRT2219039	hsa-miR-4698	CLIP-seq
MIRT2219040	hsa-miR-4709-5p	CLIP-seq
MIRT957836	hsa-miR-4731-5p	CLIP-seq
MIRT2219041	hsa-miR-4742-3p	CLIP-seq
MIRT2219042	hsa-miR-4744	CLIP-seq
MIRT2219043	hsa-miR-4762-3p	CLIP-seq
MIRT957837	hsa-miR-4766-3p	CLIP-seq
MIRT957838	hsa-miR-4789-5p	CLIP-seq
MIRT2219044	hsa-miR-4790-5p	CLIP-seq
MIRT957839	hsa-miR-4795-3p	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT957840	hsa-miR-484	CLIP-seq
MIRT957841	hsa-miR-499-5p	CLIP-seq
MIRT957842	hsa-miR-510	CLIP-seq
MIRT957843	hsa-miR-512-5p	CLIP-seq
MIRT1983725	hsa-miR-545	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT1983726	hsa-miR-548o	CLIP-seq
MIRT2219045	hsa-miR-556-5p	CLIP-seq
MIRT2219046	hsa-miR-583	CLIP-seq
MIRT1556273	hsa-miR-607	CLIP-seq
MIRT2219047	hsa-miR-618	CLIP-seq
MIRT2219048	hsa-miR-647	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT957845	hsa-miR-656	CLIP-seq
MIRT957807	hsa-miR-145	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957825	hsa-miR-377	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957825	hsa-miR-377	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT957838	hsa-miR-4789-5p	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT2219048	hsa-miR-647	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT2219024	hsa-miR-1185	CLIP-seq
MIRT2522309	hsa-miR-1238	CLIP-seq
MIRT2219025	hsa-miR-1276	CLIP-seq
MIRT2219026	hsa-miR-132	CLIP-seq
MIRT1983721	hsa-miR-1323	CLIP-seq
MIRT957806	hsa-miR-139-5p	CLIP-seq
MIRT957812	hsa-miR-183	CLIP-seq
MIRT2522310	hsa-miR-1915	CLIP-seq
MIRT957813	hsa-miR-19a	CLIP-seq
MIRT957814	hsa-miR-19b	CLIP-seq
MIRT2219027	hsa-miR-212	CLIP-seq
MIRT1983722	hsa-miR-217	CLIP-seq
MIRT957817	hsa-miR-3120-3p	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT2522311	hsa-miR-3124-3p	CLIP-seq
MIRT2522312	hsa-miR-3144-3p	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT2219029	hsa-miR-3162-3p	CLIP-seq
MIRT1983723	hsa-miR-324-5p	CLIP-seq
MIRT2522313	hsa-miR-335	CLIP-seq
MIRT957823	hsa-miR-3646	CLIP-seq
MIRT2522314	hsa-miR-3670	CLIP-seq
MIRT1556271	hsa-miR-3671	CLIP-seq
MIRT2219031	hsa-miR-3672	CLIP-seq
MIRT2219032	hsa-miR-3679-5p	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT2219033	hsa-miR-3938	CLIP-seq
MIRT957828	hsa-miR-3976	CLIP-seq
MIRT2522315	hsa-miR-4263	CLIP-seq
MIRT1983724	hsa-miR-4291	CLIP-seq
MIRT2219034	hsa-miR-4311	CLIP-seq
MIRT2219035	hsa-miR-4315	CLIP-seq
MIRT2219036	hsa-miR-4454	CLIP-seq
MIRT2522316	hsa-miR-4457	CLIP-seq
MIRT2219037	hsa-miR-4461	CLIP-seq
MIRT957832	hsa-miR-4477a	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT1556272	hsa-miR-4496	CLIP-seq
MIRT2219038	hsa-miR-4509	CLIP-seq
MIRT957834	hsa-miR-4540	CLIP-seq
MIRT2219039	hsa-miR-4698	CLIP-seq
MIRT2219040	hsa-miR-4709-5p	CLIP-seq
MIRT2522317	hsa-miR-4726-3p	CLIP-seq
MIRT2219041	hsa-miR-4742-3p	CLIP-seq
MIRT2219042	hsa-miR-4744	CLIP-seq
MIRT2219043	hsa-miR-4762-3p	CLIP-seq
MIRT957838	hsa-miR-4789-5p	CLIP-seq
MIRT2219044	hsa-miR-4790-5p	CLIP-seq
MIRT957839	hsa-miR-4795-3p	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT2522318	hsa-miR-513a-3p	CLIP-seq
MIRT2522319	hsa-miR-513b	CLIP-seq
MIRT1983725	hsa-miR-545	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT1983726	hsa-miR-548o	CLIP-seq
MIRT2219045	hsa-miR-556-5p	CLIP-seq
MIRT2522320	hsa-miR-576-5p	CLIP-seq
MIRT2219046	hsa-miR-583	CLIP-seq
MIRT1556273	hsa-miR-607	CLIP-seq
MIRT2219047	hsa-miR-618	CLIP-seq
MIRT2219048	hsa-miR-647	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT957845	hsa-miR-656	CLIP-seq
MIRT2219024	hsa-miR-1185	CLIP-seq
MIRT2522309	hsa-miR-1238	CLIP-seq
MIRT2219025	hsa-miR-1276	CLIP-seq
MIRT2219026	hsa-miR-132	CLIP-seq
MIRT1983721	hsa-miR-1323	CLIP-seq
MIRT957806	hsa-miR-139-5p	CLIP-seq
MIRT2522310	hsa-miR-1915	CLIP-seq
MIRT2219027	hsa-miR-212	CLIP-seq
MIRT1983722	hsa-miR-217	CLIP-seq
MIRT957817	hsa-miR-3120-3p	CLIP-seq
MIRT957818	hsa-miR-3123	CLIP-seq
MIRT2522311	hsa-miR-3124-3p	CLIP-seq
MIRT2522312	hsa-miR-3144-3p	CLIP-seq
MIRT739629	hsa-miR-3146	CLIP-seq
MIRT1983723	hsa-miR-324-5p	CLIP-seq
MIRT2522313	hsa-miR-335	CLIP-seq
MIRT957823	hsa-miR-3646	CLIP-seq
MIRT2522314	hsa-miR-3670	CLIP-seq
MIRT1556271	hsa-miR-3671	CLIP-seq
MIRT2219031	hsa-miR-3672	CLIP-seq
MIRT2219032	hsa-miR-3679-5p	CLIP-seq
MIRT739631	hsa-miR-3714	CLIP-seq
MIRT957824	hsa-miR-374c	CLIP-seq
MIRT957827	hsa-miR-3925-5p	CLIP-seq
MIRT2219033	hsa-miR-3938	CLIP-seq
MIRT957828	hsa-miR-3976	CLIP-seq
MIRT2522315	hsa-miR-4263	CLIP-seq
MIRT1983724	hsa-miR-4291	CLIP-seq
MIRT2219034	hsa-miR-4311	CLIP-seq
MIRT2219035	hsa-miR-4315	CLIP-seq
MIRT2219036	hsa-miR-4454	CLIP-seq
MIRT2522316	hsa-miR-4457	CLIP-seq
MIRT2219037	hsa-miR-4461	CLIP-seq
MIRT957832	hsa-miR-4477a	CLIP-seq
MIRT739632	hsa-miR-4484	CLIP-seq
MIRT1556272	hsa-miR-4496	CLIP-seq
MIRT2219038	hsa-miR-4509	CLIP-seq
MIRT957834	hsa-miR-4540	CLIP-seq
MIRT2219039	hsa-miR-4698	CLIP-seq
MIRT2219040	hsa-miR-4709-5p	CLIP-seq
MIRT2522317	hsa-miR-4726-3p	CLIP-seq
MIRT2219041	hsa-miR-4742-3p	CLIP-seq
MIRT2219042	hsa-miR-4744	CLIP-seq
MIRT2219043	hsa-miR-4762-3p	CLIP-seq
MIRT957838	hsa-miR-4789-5p	CLIP-seq
MIRT2219044	hsa-miR-4790-5p	CLIP-seq
MIRT957839	hsa-miR-4795-3p	CLIP-seq
MIRT739628	hsa-miR-4803	CLIP-seq
MIRT2522318	hsa-miR-513a-3p	CLIP-seq
MIRT2522319	hsa-miR-513b	CLIP-seq
MIRT1983725	hsa-miR-545	CLIP-seq
MIRT739630	hsa-miR-548an	CLIP-seq
MIRT1983726	hsa-miR-548o	CLIP-seq
MIRT2219045	hsa-miR-556-5p	CLIP-seq
MIRT2522320	hsa-miR-576-5p	CLIP-seq
MIRT2219046	hsa-miR-583	CLIP-seq
MIRT1556273	hsa-miR-607	CLIP-seq
MIRT2219047	hsa-miR-618	CLIP-seq
MIRT2219048	hsa-miR-647	CLIP-seq
MIRT957844	hsa-miR-655	CLIP-seq
MIRT957845	hsa-miR-656	CLIP-seq

Show/Hide all (27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002183	Process	Cytoplasmic translational initiation	IBA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003724	Function	RNA helicase activity	IEA
GO:0003743	Function	Translation initiation factor activity	IBA
GO:0003743	Function	Translation initiation factor activity	IEA
GO:0003743	Function	Translation initiation factor activity	TAS	8521730
GO:0004386	Function	Helicase activity	IEA
GO:0004386	Function	Helicase activity	TAS	8521730
GO:0005515	Function	Protein binding	IPI	11922617, 17229681, 25277244, 25416956, 31515488, 32296183, 32814053
GO:0005524	Function	ATP binding	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006412	Process	Translation	IEA
GO:0006413	Process	Translational initiation	IEA
GO:0006413	Process	Translational initiation	NAS	19239892
GO:0006446	Process	Regulation of translational initiation	TAS	8521730
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	IEA
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	NAS	19239892
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	TAS	8521730
GO:0016787	Function	Hydrolase activity	IEA
GO:0016887	Function	ATP hydrolysis activity	IDA	11922617
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	11922617
GO:1900260	Process	Negative regulation of RNA-dependent RNA polymerase activity	IDA	11922617
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA

MIM	HGNC	e!Ensembl
601102	3284	ENSG00000156976

Q14240

Protein name

Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)

Protein function

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of

PDB

3BOR

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00270	DEAD	57 → 224	DEAD/DEAH box helicase	Domain
PF00271	Helicase_C	259 → 368	Helicase conserved C-terminal domain	Family

Sequence

MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ
QRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKV
ILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMF
VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE
ELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTV
SALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHR
IGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI

Sequence length

407

Interactions

View interactions

	Reactome
			ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit

Show/Hide Causal Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Intellectual disability with muscular spams	Likely pathogenic; Pathogenic	rs2108458617	RCV002276523
Neurodevelopmental delay	Likely pathogenic; Pathogenic	rs2108464046	RCV001838852
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs2473968343, rs764605841, rs1171371205, rs2473961744, rs2108458548, rs2473970931, rs2473970934, rs2473975415, rs2473976527	RCV003223435 RCV002300687 RCV002300688 RCV002300689 RCV002300691 RCV002300692 RCV002300693 RCV002300694 RCV002300695
Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures	Likely pathogenic; Pathogenic	rs2108458617, rs2108464046, rs2473961852, rs2473983738, rs2473970934, rs2473976527, rs112754953	RCV003319229 RCV003388614 RCV003319235 RCV003319236 RCV003319233 RCV003319234 RCV003494075

Show/Hide Unknown Diseases (17)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs75837460	RCV005938947
Cervical cancer	Benign	rs75837460	RCV005938951
Clear cell carcinoma of kidney	Benign	rs75837460	RCV005938953
Colon adenocarcinoma	Benign	rs75837460	RCV005938946
Colorectal cancer	Benign	rs75837460	RCV005938955
EIF4A2-related disorder	Uncertain significance; Likely benign; Benign	rs2473955808, rs377170945, rs2473968386, rs201090177, rs1721607584, rs80057919, rs75837460, rs11538612, rs181852973	RCV003402936 RCV003907023 RCV003893598 RCV003981412 RCV003897215 RCV003952015 RCV003917388 RCV003924495 RCV003971400
EIF4A2-related Neurodevelopmental Syndrome	Uncertain significance	rs2473976506	RCV003448598
Hepatocellular carcinoma	Benign	rs75837460	RCV005938948
Lung cancer	Benign	rs75837460	RCV005938960
Lymphoma	Benign	rs75837460	RCV005938957
Malignant lymphoma, large B-cell, diffuse	Benign	rs75837460	RCV005938954
Malignant tumor of esophagus	Benign	rs75837460	RCV005938949
Melanoma	Benign	rs75837460	RCV005938959
Nonpapillary renal cell carcinoma	Benign	rs75837460	RCV005938950
Ovarian cancer	Benign	rs75837460	RCV005938952
Ovarian serous cystadenocarcinoma	Benign	rs75837460	RCV005938958
Sarcoma	Benign	rs75837460	RCV005938956

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acidosis	Stimulate	26274822
Alzheimer Disease	Associate	20927385, 22016602
Carcinogenesis	Associate	20145189
Carcinoma Hepatocellular	Associate	12521301
Colorectal Neoplasms	Associate	24113185
Glioma	Associate	37192718
Hypoxia	Stimulate	26274822
Inflammation	Associate	26986695
Leukemia Lymphocytic Chronic B Cell	Associate	34398253
Leukemia Myeloid Acute	Associate	35781533
Lung Neoplasms	Associate	37384411
Lymphoma	Associate	25320244
Lymphoma B Cell	Associate	25320244, 34398253
Lymphoma Large B Cell Diffuse	Associate	25320244
Melanoma	Associate	31844050
Meningioma	Associate	28610844
Neoplasms	Associate	20145189, 26275051, 33027666, 36761744, 37384411, 37405918
Oncogene Addiction	Associate	25320244
Triple Negative Breast Neoplasms	Associate	31308851
Urinary Bladder Neoplasms	Associate	36761744

EIF4A2 (eukaryotic translation initiation factor 4A2)