Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1876
Gene name Gene Name - the full gene name approved by the HGNC.	E2F transcription factor 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	E2F6
Synonyms (NCBI Gene) Gene synonyms aliases	E2F-6
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p25.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family me

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004726	hsa-miR-124-3p	Luciferase reporter assay, qRT-PCR, Western blot	19843643
MIRT004726	hsa-miR-124-3p	Luciferase reporter assay, qRT-PCR, Western blot	19843643
MIRT004726	hsa-miR-124-3p	Luciferase reporter assay, qRT-PCR, Western blot	19843643
MIRT004726	hsa-miR-124-3p	Luciferase reporter assay, qRT-PCR, Western blot	19843643
MIRT005044	hsa-let-7b-5p	Microarray	17699775
MIRT002489	hsa-miR-137	Luciferase reporter assay, qRT-PCR, Western blot	18381414
MIRT002487	hsa-miR-193a-3p	Luciferase reporter assay, qRT-PCR, Western blot	18381414
MIRT006419	hsa-miR-28-5p	Luciferase reporter assay	20445018
MIRT006420	hsa-miR-151a-5p	Luciferase reporter assay	20445018
MIRT006420	hsa-miR-151a-5p	Luciferase reporter assay	20445018
MIRT006420	hsa-miR-151a-5p	Luciferase reporter assay	20445018
MIRT016420	hsa-miR-193b-3p	Microarray	20304954
MIRT027682	hsa-miR-98-5p	Microarray	19088304
MIRT567719	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT005044	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT567718	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT567717	hsa-miR-4458	PAR-CLIP	20371350
MIRT567716	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT567715	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT567714	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT567713	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT567712	hsa-miR-4500	PAR-CLIP	20371350
MIRT027682	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT567711	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT567710	hsa-miR-3927-3p	PAR-CLIP	20371350
MIRT567709	hsa-miR-6831-5p	PAR-CLIP	20371350
MIRT502601	hsa-miR-4678	PAR-CLIP	20371350
MIRT502600	hsa-miR-4501	PAR-CLIP	20371350
MIRT502599	hsa-miR-299-3p	PAR-CLIP	20371350
MIRT502597	hsa-miR-4468	PAR-CLIP	20371350
MIRT567708	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT502598	hsa-miR-6081	PAR-CLIP	20371350
MIRT502596	hsa-miR-6827-5p	PAR-CLIP	20371350
MIRT502595	hsa-miR-6090	PAR-CLIP	20371350
MIRT502594	hsa-miR-4300	PAR-CLIP	20371350
MIRT502593	hsa-miR-5591-5p	PAR-CLIP	20371350
MIRT502592	hsa-miR-6726-5p	PAR-CLIP	20371350
MIRT502591	hsa-miR-920	PAR-CLIP	20371350
MIRT567707	hsa-miR-4650-3p	PAR-CLIP	20371350
MIRT502590	hsa-miR-4648	PAR-CLIP	20371350
MIRT502589	hsa-miR-1233-5p	PAR-CLIP	20371350
MIRT502588	hsa-miR-6778-5p	PAR-CLIP	20371350
MIRT502587	hsa-miR-4654	PAR-CLIP	20371350
MIRT502586	hsa-miR-4769-5p	PAR-CLIP	20371350
MIRT567706	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT502585	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT502583	hsa-miR-6766-5p	PAR-CLIP	20371350
MIRT502601	hsa-miR-4678	PAR-CLIP	24398324
MIRT502600	hsa-miR-4501	PAR-CLIP	24398324
MIRT502599	hsa-miR-299-3p	PAR-CLIP	24398324
MIRT502597	hsa-miR-4468	PAR-CLIP	24398324
MIRT502598	hsa-miR-6081	PAR-CLIP	24398324
MIRT502596	hsa-miR-6827-5p	PAR-CLIP	24398324
MIRT502595	hsa-miR-6090	PAR-CLIP	24398324
MIRT502594	hsa-miR-4300	PAR-CLIP	24398324
MIRT502593	hsa-miR-5591-5p	PAR-CLIP	24398324
MIRT502592	hsa-miR-6726-5p	PAR-CLIP	24398324
MIRT502591	hsa-miR-920	PAR-CLIP	24398324
MIRT502590	hsa-miR-4648	PAR-CLIP	24398324
MIRT502589	hsa-miR-1233-5p	PAR-CLIP	24398324
MIRT502588	hsa-miR-6778-5p	PAR-CLIP	24398324
MIRT502587	hsa-miR-4654	PAR-CLIP	24398324
MIRT502586	hsa-miR-4769-5p	PAR-CLIP	24398324
MIRT502585	hsa-miR-331-5p	PAR-CLIP	24398324
MIRT502583	hsa-miR-6766-5p	PAR-CLIP	24398324
MIRT502584	hsa-miR-548av-3p	PAR-CLIP	24398324
MIRT502582	hsa-miR-548g-3p	PAR-CLIP	24398324
MIRT502580	hsa-miR-3646	PAR-CLIP	24398324
MIRT502581	hsa-miR-1252-3p	PAR-CLIP	24398324
MIRT502579	hsa-miR-4797-5p	PAR-CLIP	24398324
MIRT502578	hsa-miR-5582-5p	PAR-CLIP	24398324
MIRT502577	hsa-miR-759	PAR-CLIP	24398324
MIRT502576	hsa-miR-4649-3p	PAR-CLIP	24398324
MIRT502575	hsa-miR-1827	PAR-CLIP	24398324
MIRT002487	hsa-miR-193a-3p	qRT-PCR, Western blot	26125439
MIRT502589	hsa-miR-1233-5p	PAR-CLIP	26701625
MIRT502599	hsa-miR-299-3p	PAR-CLIP	26701625
MIRT502594	hsa-miR-4300	PAR-CLIP	26701625
MIRT502597	hsa-miR-4468	PAR-CLIP	26701625
MIRT502590	hsa-miR-4648	PAR-CLIP	26701625
MIRT502587	hsa-miR-4654	PAR-CLIP	26701625
MIRT502586	hsa-miR-4769-5p	PAR-CLIP	26701625
MIRT502593	hsa-miR-5591-5p	PAR-CLIP	26701625
MIRT502598	hsa-miR-6081	PAR-CLIP	26701625
MIRT502595	hsa-miR-6090	PAR-CLIP	26701625
MIRT502592	hsa-miR-6726-5p	PAR-CLIP	26701625
MIRT502583	hsa-miR-6766-5p	PAR-CLIP	26701625
MIRT502588	hsa-miR-6778-5p	PAR-CLIP	26701625
MIRT502596	hsa-miR-6827-5p	PAR-CLIP	26701625
MIRT502591	hsa-miR-920	PAR-CLIP	26701625
MIRT567719	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT005044	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT567718	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT567717	hsa-miR-4458	PAR-CLIP	20371350
MIRT567716	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT567715	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT567714	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT567713	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT567712	hsa-miR-4500	PAR-CLIP	20371350
MIRT027682	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT567711	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT567710	hsa-miR-3927-3p	PAR-CLIP	20371350
MIRT567709	hsa-miR-6831-5p	PAR-CLIP	20371350
MIRT502601	hsa-miR-4678	PAR-CLIP	20371350
MIRT502600	hsa-miR-4501	PAR-CLIP	20371350
MIRT502599	hsa-miR-299-3p	PAR-CLIP	20371350
MIRT502597	hsa-miR-4468	PAR-CLIP	20371350
MIRT567708	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT502598	hsa-miR-6081	PAR-CLIP	20371350
MIRT502596	hsa-miR-6827-5p	PAR-CLIP	20371350
MIRT502595	hsa-miR-6090	PAR-CLIP	20371350
MIRT502594	hsa-miR-4300	PAR-CLIP	20371350
MIRT502593	hsa-miR-5591-5p	PAR-CLIP	20371350
MIRT502592	hsa-miR-6726-5p	PAR-CLIP	20371350
MIRT502591	hsa-miR-920	PAR-CLIP	20371350
MIRT567707	hsa-miR-4650-3p	PAR-CLIP	20371350
MIRT502590	hsa-miR-4648	PAR-CLIP	20371350
MIRT502589	hsa-miR-1233-5p	PAR-CLIP	20371350
MIRT502588	hsa-miR-6778-5p	PAR-CLIP	20371350
MIRT502587	hsa-miR-4654	PAR-CLIP	20371350
MIRT502586	hsa-miR-4769-5p	PAR-CLIP	20371350
MIRT567706	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT502585	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT502583	hsa-miR-6766-5p	PAR-CLIP	20371350
MIRT502601	hsa-miR-4678	PAR-CLIP	24398324
MIRT502600	hsa-miR-4501	PAR-CLIP	24398324
MIRT502599	hsa-miR-299-3p	PAR-CLIP	24398324
MIRT502597	hsa-miR-4468	PAR-CLIP	24398324
MIRT502598	hsa-miR-6081	PAR-CLIP	24398324
MIRT502596	hsa-miR-6827-5p	PAR-CLIP	24398324
MIRT502595	hsa-miR-6090	PAR-CLIP	24398324
MIRT502594	hsa-miR-4300	PAR-CLIP	24398324
MIRT502593	hsa-miR-5591-5p	PAR-CLIP	24398324
MIRT502592	hsa-miR-6726-5p	PAR-CLIP	24398324
MIRT502591	hsa-miR-920	PAR-CLIP	24398324
MIRT502590	hsa-miR-4648	PAR-CLIP	24398324
MIRT502589	hsa-miR-1233-5p	PAR-CLIP	24398324
MIRT502588	hsa-miR-6778-5p	PAR-CLIP	24398324
MIRT502587	hsa-miR-4654	PAR-CLIP	24398324
MIRT502586	hsa-miR-4769-5p	PAR-CLIP	24398324
MIRT502585	hsa-miR-331-5p	PAR-CLIP	24398324
MIRT502583	hsa-miR-6766-5p	PAR-CLIP	24398324
MIRT502584	hsa-miR-548av-3p	PAR-CLIP	24398324
MIRT502582	hsa-miR-548g-3p	PAR-CLIP	24398324
MIRT502580	hsa-miR-3646	PAR-CLIP	24398324
MIRT502581	hsa-miR-1252-3p	PAR-CLIP	24398324
MIRT502579	hsa-miR-4797-5p	PAR-CLIP	24398324
MIRT502578	hsa-miR-5582-5p	PAR-CLIP	24398324
MIRT502577	hsa-miR-759	PAR-CLIP	24398324
MIRT502576	hsa-miR-4649-3p	PAR-CLIP	24398324
MIRT502575	hsa-miR-1827	PAR-CLIP	24398324
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950712	hsa-miR-105	CLIP-seq
MIRT950713	hsa-miR-1184	CLIP-seq
MIRT950714	hsa-miR-122	CLIP-seq
MIRT950715	hsa-miR-1231	CLIP-seq
MIRT950716	hsa-miR-1261	CLIP-seq
MIRT950717	hsa-miR-127-5p	CLIP-seq
MIRT950718	hsa-miR-128	CLIP-seq
MIRT950719	hsa-miR-1294	CLIP-seq
MIRT950720	hsa-miR-1301	CLIP-seq
MIRT950721	hsa-miR-1303	CLIP-seq
MIRT950722	hsa-miR-1305	CLIP-seq
MIRT950723	hsa-miR-132	CLIP-seq
MIRT950724	hsa-miR-1322	CLIP-seq
MIRT950725	hsa-miR-1324	CLIP-seq
MIRT950726	hsa-miR-146a	CLIP-seq
MIRT950727	hsa-miR-146b-5p	CLIP-seq
MIRT950728	hsa-miR-1825	CLIP-seq
MIRT950729	hsa-miR-185	CLIP-seq
MIRT950730	hsa-miR-193b	CLIP-seq
MIRT950731	hsa-miR-194	CLIP-seq
MIRT950732	hsa-miR-196a	CLIP-seq
MIRT950733	hsa-miR-196b	CLIP-seq
MIRT950734	hsa-miR-199a-5p	CLIP-seq
MIRT950735	hsa-miR-199b-5p	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950737	hsa-miR-2114	CLIP-seq
MIRT950738	hsa-miR-212	CLIP-seq
MIRT950739	hsa-miR-214	CLIP-seq
MIRT950740	hsa-miR-216a	CLIP-seq
MIRT950741	hsa-miR-216b	CLIP-seq
MIRT950742	hsa-miR-23a	CLIP-seq
MIRT950743	hsa-miR-23b	CLIP-seq
MIRT950744	hsa-miR-23c	CLIP-seq
MIRT950745	hsa-miR-2467-3p	CLIP-seq
MIRT950746	hsa-miR-27a	CLIP-seq
MIRT950747	hsa-miR-27b	CLIP-seq
MIRT950748	hsa-miR-300	CLIP-seq
MIRT950749	hsa-miR-31	CLIP-seq
MIRT950750	hsa-miR-3117-5p	CLIP-seq
MIRT950751	hsa-miR-3120-3p	CLIP-seq
MIRT950752	hsa-miR-3123	CLIP-seq
MIRT950753	hsa-miR-3126-5p	CLIP-seq
MIRT950754	hsa-miR-3128	CLIP-seq
MIRT950755	hsa-miR-3139	CLIP-seq
MIRT950756	hsa-miR-3169	CLIP-seq
MIRT950757	hsa-miR-3187-3p	CLIP-seq
MIRT950758	hsa-miR-3190	CLIP-seq
MIRT950759	hsa-miR-3194-3p	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT950761	hsa-miR-3529	CLIP-seq
MIRT950762	hsa-miR-3607-3p	CLIP-seq
MIRT950763	hsa-miR-3612	CLIP-seq
MIRT950764	hsa-miR-3617	CLIP-seq
MIRT950765	hsa-miR-3619-5p	CLIP-seq
MIRT950766	hsa-miR-3622b-5p	CLIP-seq
MIRT950767	hsa-miR-3647-3p	CLIP-seq
MIRT950768	hsa-miR-3650	CLIP-seq
MIRT950769	hsa-miR-3663-3p	CLIP-seq
MIRT950770	hsa-miR-3664-5p	CLIP-seq
MIRT950771	hsa-miR-3670	CLIP-seq
MIRT950772	hsa-miR-3671	CLIP-seq
MIRT950773	hsa-miR-3682-3p	CLIP-seq
MIRT950774	hsa-miR-3682-5p	CLIP-seq
MIRT950775	hsa-miR-3686	CLIP-seq
MIRT950776	hsa-miR-371b-3p	CLIP-seq
MIRT950777	hsa-miR-375	CLIP-seq
MIRT950778	hsa-miR-379	CLIP-seq
MIRT950779	hsa-miR-381	CLIP-seq
MIRT950780	hsa-miR-383	CLIP-seq
MIRT950781	hsa-miR-3913-3p	CLIP-seq
MIRT950782	hsa-miR-3921	CLIP-seq
MIRT950783	hsa-miR-3925-5p	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950785	hsa-miR-3942-5p	CLIP-seq
MIRT950786	hsa-miR-425	CLIP-seq
MIRT950787	hsa-miR-4251	CLIP-seq
MIRT950788	hsa-miR-4261	CLIP-seq
MIRT950789	hsa-miR-4268	CLIP-seq
MIRT950790	hsa-miR-4272	CLIP-seq
MIRT950791	hsa-miR-4275	CLIP-seq
MIRT950792	hsa-miR-4288	CLIP-seq
MIRT950793	hsa-miR-4291	CLIP-seq
MIRT950794	hsa-miR-4311	CLIP-seq
MIRT950795	hsa-miR-4313	CLIP-seq
MIRT950796	hsa-miR-4316	CLIP-seq
MIRT950797	hsa-miR-4320	CLIP-seq
MIRT950798	hsa-miR-4329	CLIP-seq
MIRT950799	hsa-miR-433	CLIP-seq
MIRT950800	hsa-miR-4420	CLIP-seq
MIRT950801	hsa-miR-4433	CLIP-seq
MIRT950802	hsa-miR-4448	CLIP-seq
MIRT950803	hsa-miR-4459	CLIP-seq
MIRT950804	hsa-miR-4461	CLIP-seq
MIRT950805	hsa-miR-4470	CLIP-seq
MIRT950806	hsa-miR-4491	CLIP-seq
MIRT950807	hsa-miR-4519	CLIP-seq
MIRT950808	hsa-miR-4528	CLIP-seq
MIRT950809	hsa-miR-4529-5p	CLIP-seq
MIRT950810	hsa-miR-455-3p	CLIP-seq
MIRT950811	hsa-miR-4640-5p	CLIP-seq
MIRT950812	hsa-miR-4645-5p	CLIP-seq
MIRT950813	hsa-miR-4653-5p	CLIP-seq
MIRT950814	hsa-miR-4657	CLIP-seq
MIRT950815	hsa-miR-4660	CLIP-seq
MIRT950816	hsa-miR-4666-3p	CLIP-seq
MIRT950817	hsa-miR-4673	CLIP-seq
MIRT950818	hsa-miR-4677-3p	CLIP-seq
MIRT950819	hsa-miR-4679	CLIP-seq
MIRT950820	hsa-miR-4680-5p	CLIP-seq
MIRT950821	hsa-miR-4687-3p	CLIP-seq
MIRT950822	hsa-miR-4695-5p	CLIP-seq
MIRT950823	hsa-miR-4700-3p	CLIP-seq
MIRT950824	hsa-miR-4703-5p	CLIP-seq
MIRT950825	hsa-miR-4708-3p	CLIP-seq
MIRT950826	hsa-miR-4718	CLIP-seq
MIRT950827	hsa-miR-4726-5p	CLIP-seq
MIRT950828	hsa-miR-4729	CLIP-seq
MIRT950829	hsa-miR-4731-3p	CLIP-seq
MIRT950830	hsa-miR-4735-5p	CLIP-seq
MIRT950831	hsa-miR-4742-3p	CLIP-seq
MIRT950832	hsa-miR-4755-3p	CLIP-seq
MIRT950833	hsa-miR-4762-3p	CLIP-seq
MIRT950834	hsa-miR-4766-5p	CLIP-seq
MIRT950835	hsa-miR-4768-3p	CLIP-seq
MIRT950836	hsa-miR-4772-5p	CLIP-seq
MIRT950837	hsa-miR-4778-5p	CLIP-seq
MIRT950838	hsa-miR-4789-5p	CLIP-seq
MIRT950839	hsa-miR-4795-3p	CLIP-seq
MIRT950840	hsa-miR-4796-5p	CLIP-seq
MIRT950841	hsa-miR-4797-3p	CLIP-seq
MIRT950842	hsa-miR-4801	CLIP-seq
MIRT950843	hsa-miR-4803	CLIP-seq
MIRT950844	hsa-miR-486-5p	CLIP-seq
MIRT950845	hsa-miR-488	CLIP-seq
MIRT950846	hsa-miR-490-5p	CLIP-seq
MIRT950847	hsa-miR-499-3p	CLIP-seq
MIRT950848	hsa-miR-499a-3p	CLIP-seq
MIRT950849	hsa-miR-5047	CLIP-seq
MIRT950850	hsa-miR-510	CLIP-seq
MIRT950851	hsa-miR-512-5p	CLIP-seq
MIRT950852	hsa-miR-515-5p	CLIP-seq
MIRT950853	hsa-miR-518a-5p	CLIP-seq
MIRT950854	hsa-miR-520a-5p	CLIP-seq
MIRT950855	hsa-miR-520d-5p	CLIP-seq
MIRT950856	hsa-miR-524-5p	CLIP-seq
MIRT950857	hsa-miR-525-5p	CLIP-seq
MIRT950858	hsa-miR-527	CLIP-seq
MIRT950859	hsa-miR-548ac	CLIP-seq
MIRT950860	hsa-miR-548d-3p	CLIP-seq
MIRT950861	hsa-miR-548g	CLIP-seq
MIRT950862	hsa-miR-548t	CLIP-seq
MIRT950863	hsa-miR-548z	CLIP-seq
MIRT950864	hsa-miR-576-5p	CLIP-seq
MIRT950865	hsa-miR-579	CLIP-seq
MIRT950866	hsa-miR-580	CLIP-seq
MIRT950867	hsa-miR-587	CLIP-seq
MIRT950868	hsa-miR-589	CLIP-seq
MIRT950869	hsa-miR-597	CLIP-seq
MIRT950870	hsa-miR-605	CLIP-seq
MIRT950871	hsa-miR-607	CLIP-seq
MIRT950872	hsa-miR-624	CLIP-seq
MIRT950873	hsa-miR-630	CLIP-seq
MIRT950874	hsa-miR-632	CLIP-seq
MIRT950875	hsa-miR-641	CLIP-seq
MIRT950876	hsa-miR-645	CLIP-seq
MIRT950877	hsa-miR-647	CLIP-seq
MIRT950878	hsa-miR-650	CLIP-seq
MIRT950879	hsa-miR-656	CLIP-seq
MIRT950880	hsa-miR-668	CLIP-seq
MIRT950881	hsa-miR-676	CLIP-seq
MIRT950882	hsa-miR-708	CLIP-seq
MIRT950883	hsa-miR-761	CLIP-seq
MIRT950884	hsa-miR-892b	CLIP-seq
MIRT950885	hsa-miR-9	CLIP-seq
MIRT950886	hsa-miR-922	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT1981584	hsa-miR-124	CLIP-seq
MIRT950716	hsa-miR-1261	CLIP-seq
MIRT1981585	hsa-miR-1269	CLIP-seq
MIRT950717	hsa-miR-127-5p	CLIP-seq
MIRT950718	hsa-miR-128	CLIP-seq
MIRT1981586	hsa-miR-1288	CLIP-seq
MIRT950725	hsa-miR-1324	CLIP-seq
MIRT950726	hsa-miR-146a	CLIP-seq
MIRT950727	hsa-miR-146b-5p	CLIP-seq
MIRT950734	hsa-miR-199a-5p	CLIP-seq
MIRT950735	hsa-miR-199b-5p	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT1981587	hsa-miR-2113	CLIP-seq
MIRT950737	hsa-miR-2114	CLIP-seq
MIRT950739	hsa-miR-214	CLIP-seq
MIRT950740	hsa-miR-216a	CLIP-seq
MIRT950741	hsa-miR-216b	CLIP-seq
MIRT950742	hsa-miR-23a	CLIP-seq
MIRT950743	hsa-miR-23b	CLIP-seq
MIRT950744	hsa-miR-23c	CLIP-seq
MIRT950746	hsa-miR-27a	CLIP-seq
MIRT950747	hsa-miR-27b	CLIP-seq
MIRT950748	hsa-miR-300	CLIP-seq
MIRT950749	hsa-miR-31	CLIP-seq
MIRT950750	hsa-miR-3117-5p	CLIP-seq
MIRT950751	hsa-miR-3120-3p	CLIP-seq
MIRT1981588	hsa-miR-3120-5p	CLIP-seq
MIRT950755	hsa-miR-3139	CLIP-seq
MIRT1981589	hsa-miR-3157-5p	CLIP-seq
MIRT950759	hsa-miR-3194-3p	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT1981590	hsa-miR-345	CLIP-seq
MIRT950763	hsa-miR-3612	CLIP-seq
MIRT1981591	hsa-miR-3613-3p	CLIP-seq
MIRT950764	hsa-miR-3617	CLIP-seq
MIRT950765	hsa-miR-3619-5p	CLIP-seq
MIRT1981592	hsa-miR-362-5p	CLIP-seq
MIRT950767	hsa-miR-3647-3p	CLIP-seq
MIRT950769	hsa-miR-3663-3p	CLIP-seq
MIRT950770	hsa-miR-3664-5p	CLIP-seq
MIRT950771	hsa-miR-3670	CLIP-seq
MIRT950772	hsa-miR-3671	CLIP-seq
MIRT1981593	hsa-miR-3680	CLIP-seq
MIRT1981594	hsa-miR-3689a-5p	CLIP-seq
MIRT1981595	hsa-miR-3689b	CLIP-seq
MIRT1981596	hsa-miR-3689e	CLIP-seq
MIRT1981597	hsa-miR-3689f	CLIP-seq
MIRT1981598	hsa-miR-3714	CLIP-seq
MIRT950777	hsa-miR-375	CLIP-seq
MIRT950779	hsa-miR-381	CLIP-seq
MIRT1981599	hsa-miR-3910	CLIP-seq
MIRT950781	hsa-miR-3913-3p	CLIP-seq
MIRT950782	hsa-miR-3921	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT1981600	hsa-miR-3938	CLIP-seq
MIRT950786	hsa-miR-425	CLIP-seq
MIRT950787	hsa-miR-4251	CLIP-seq
MIRT950790	hsa-miR-4272	CLIP-seq
MIRT1981601	hsa-miR-4276	CLIP-seq
MIRT950793	hsa-miR-4291	CLIP-seq
MIRT1981602	hsa-miR-4293	CLIP-seq
MIRT950795	hsa-miR-4313	CLIP-seq
MIRT950798	hsa-miR-4329	CLIP-seq
MIRT950799	hsa-miR-433	CLIP-seq
MIRT950801	hsa-miR-4433	CLIP-seq
MIRT1981603	hsa-miR-4452	CLIP-seq
MIRT950803	hsa-miR-4459	CLIP-seq
MIRT950804	hsa-miR-4461	CLIP-seq
MIRT950806	hsa-miR-4491	CLIP-seq
MIRT950807	hsa-miR-4519	CLIP-seq
MIRT950808	hsa-miR-4528	CLIP-seq
MIRT950813	hsa-miR-4653-5p	CLIP-seq
MIRT950814	hsa-miR-4657	CLIP-seq
MIRT950816	hsa-miR-4666-3p	CLIP-seq
MIRT950818	hsa-miR-4677-3p	CLIP-seq
MIRT950819	hsa-miR-4679	CLIP-seq
MIRT950820	hsa-miR-4680-5p	CLIP-seq
MIRT950821	hsa-miR-4687-3p	CLIP-seq
MIRT950822	hsa-miR-4695-5p	CLIP-seq
MIRT950825	hsa-miR-4708-3p	CLIP-seq
MIRT950826	hsa-miR-4718	CLIP-seq
MIRT950828	hsa-miR-4729	CLIP-seq
MIRT950829	hsa-miR-4731-3p	CLIP-seq
MIRT950835	hsa-miR-4768-3p	CLIP-seq
MIRT950838	hsa-miR-4789-5p	CLIP-seq
MIRT950842	hsa-miR-4801	CLIP-seq
MIRT950846	hsa-miR-490-5p	CLIP-seq
MIRT950847	hsa-miR-499-3p	CLIP-seq
MIRT950848	hsa-miR-499a-3p	CLIP-seq
MIRT1981604	hsa-miR-500b	CLIP-seq
MIRT1981605	hsa-miR-501-5p	CLIP-seq
MIRT1981606	hsa-miR-506	CLIP-seq
MIRT1981607	hsa-miR-513b	CLIP-seq
MIRT950852	hsa-miR-515-5p	CLIP-seq
MIRT950855	hsa-miR-520d-5p	CLIP-seq
MIRT950856	hsa-miR-524-5p	CLIP-seq
MIRT1981608	hsa-miR-548ae	CLIP-seq
MIRT1981609	hsa-miR-548aj	CLIP-seq
MIRT1981610	hsa-miR-548am	CLIP-seq
MIRT950862	hsa-miR-548t	CLIP-seq
MIRT1981611	hsa-miR-548x	CLIP-seq
MIRT950866	hsa-miR-580	CLIP-seq
MIRT950867	hsa-miR-587	CLIP-seq
MIRT950868	hsa-miR-589	CLIP-seq
MIRT950869	hsa-miR-597	CLIP-seq
MIRT950871	hsa-miR-607	CLIP-seq
MIRT950872	hsa-miR-624	CLIP-seq
MIRT950875	hsa-miR-641	CLIP-seq
MIRT950877	hsa-miR-647	CLIP-seq
MIRT950878	hsa-miR-650	CLIP-seq
MIRT950880	hsa-miR-668	CLIP-seq
MIRT950881	hsa-miR-676	CLIP-seq
MIRT950882	hsa-miR-708	CLIP-seq
MIRT1981612	hsa-miR-758	CLIP-seq
MIRT950883	hsa-miR-761	CLIP-seq
MIRT950885	hsa-miR-9	CLIP-seq
MIRT950886	hsa-miR-922	CLIP-seq
MIRT1981613	hsa-miR-943	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950716	hsa-miR-1261	CLIP-seq
MIRT1981585	hsa-miR-1269	CLIP-seq
MIRT950718	hsa-miR-128	CLIP-seq
MIRT1981586	hsa-miR-1288	CLIP-seq
MIRT950719	hsa-miR-1294	CLIP-seq
MIRT950725	hsa-miR-1324	CLIP-seq
MIRT950726	hsa-miR-146a	CLIP-seq
MIRT950727	hsa-miR-146b-5p	CLIP-seq
MIRT950731	hsa-miR-194	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950737	hsa-miR-2114	CLIP-seq
MIRT950740	hsa-miR-216a	CLIP-seq
MIRT950741	hsa-miR-216b	CLIP-seq
MIRT950746	hsa-miR-27a	CLIP-seq
MIRT950747	hsa-miR-27b	CLIP-seq
MIRT950751	hsa-miR-3120-3p	CLIP-seq
MIRT950758	hsa-miR-3190	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT2216575	hsa-miR-329	CLIP-seq
MIRT1981590	hsa-miR-345	CLIP-seq
MIRT950766	hsa-miR-3622b-5p	CLIP-seq
MIRT2216576	hsa-miR-362-3p	CLIP-seq
MIRT950767	hsa-miR-3647-3p	CLIP-seq
MIRT950768	hsa-miR-3650	CLIP-seq
MIRT950769	hsa-miR-3663-3p	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT1981600	hsa-miR-3938	CLIP-seq
MIRT950788	hsa-miR-4261	CLIP-seq
MIRT950791	hsa-miR-4275	CLIP-seq
MIRT950796	hsa-miR-4316	CLIP-seq
MIRT1981603	hsa-miR-4452	CLIP-seq
MIRT950804	hsa-miR-4461	CLIP-seq
MIRT950806	hsa-miR-4491	CLIP-seq
MIRT950808	hsa-miR-4528	CLIP-seq
MIRT950811	hsa-miR-4640-5p	CLIP-seq
MIRT950812	hsa-miR-4645-5p	CLIP-seq
MIRT950814	hsa-miR-4657	CLIP-seq
MIRT950817	hsa-miR-4673	CLIP-seq
MIRT2216577	hsa-miR-4680-3p	CLIP-seq
MIRT950820	hsa-miR-4680-5p	CLIP-seq
MIRT950821	hsa-miR-4687-3p	CLIP-seq
MIRT950823	hsa-miR-4700-3p	CLIP-seq
MIRT950825	hsa-miR-4708-3p	CLIP-seq
MIRT950826	hsa-miR-4718	CLIP-seq
MIRT950827	hsa-miR-4726-5p	CLIP-seq
MIRT950828	hsa-miR-4729	CLIP-seq
MIRT950829	hsa-miR-4731-3p	CLIP-seq
MIRT950831	hsa-miR-4742-3p	CLIP-seq
MIRT950832	hsa-miR-4755-3p	CLIP-seq
MIRT2216578	hsa-miR-4760-3p	CLIP-seq
MIRT950838	hsa-miR-4789-5p	CLIP-seq
MIRT950841	hsa-miR-4797-3p	CLIP-seq
MIRT950842	hsa-miR-4801	CLIP-seq
MIRT950846	hsa-miR-490-5p	CLIP-seq
MIRT950850	hsa-miR-510	CLIP-seq
MIRT950851	hsa-miR-512-5p	CLIP-seq
MIRT1981607	hsa-miR-513b	CLIP-seq
MIRT950855	hsa-miR-520d-5p	CLIP-seq
MIRT950856	hsa-miR-524-5p	CLIP-seq
MIRT950861	hsa-miR-548g	CLIP-seq
MIRT950862	hsa-miR-548t	CLIP-seq
MIRT950868	hsa-miR-589	CLIP-seq
MIRT950869	hsa-miR-597	CLIP-seq
MIRT950872	hsa-miR-624	CLIP-seq
MIRT950877	hsa-miR-647	CLIP-seq
MIRT950880	hsa-miR-668	CLIP-seq
MIRT2216579	hsa-miR-767-3p	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950766	hsa-miR-3622b-5p	CLIP-seq
MIRT950768	hsa-miR-3650	CLIP-seq
MIRT950769	hsa-miR-3663-3p	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950811	hsa-miR-4640-5p	CLIP-seq
MIRT950812	hsa-miR-4645-5p	CLIP-seq
MIRT2387198	hsa-miR-4666-5p	CLIP-seq
MIRT950817	hsa-miR-4673	CLIP-seq
MIRT2387199	hsa-miR-4695-3p	CLIP-seq
MIRT950827	hsa-miR-4726-5p	CLIP-seq
MIRT950832	hsa-miR-4755-3p	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950867	hsa-miR-587	CLIP-seq
MIRT950880	hsa-miR-668	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950772	hsa-miR-3671	CLIP-seq
MIRT950871	hsa-miR-607	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950712	hsa-miR-105	CLIP-seq
MIRT950722	hsa-miR-1305	CLIP-seq
MIRT950729	hsa-miR-185	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950751	hsa-miR-3120-3p	CLIP-seq
MIRT2520453	hsa-miR-3136-5p	CLIP-seq
MIRT2520454	hsa-miR-3145-5p	CLIP-seq
MIRT2520455	hsa-miR-3163	CLIP-seq
MIRT950758	hsa-miR-3190	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT2520456	hsa-miR-340	CLIP-seq
MIRT950767	hsa-miR-3647-3p	CLIP-seq
MIRT950772	hsa-miR-3671	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT950788	hsa-miR-4261	CLIP-seq
MIRT950791	hsa-miR-4275	CLIP-seq
MIRT2520457	hsa-miR-4439	CLIP-seq
MIRT1981603	hsa-miR-4452	CLIP-seq
MIRT950806	hsa-miR-4491	CLIP-seq
MIRT950807	hsa-miR-4519	CLIP-seq
MIRT950814	hsa-miR-4657	CLIP-seq
MIRT2216577	hsa-miR-4680-3p	CLIP-seq
MIRT950825	hsa-miR-4708-3p	CLIP-seq
MIRT950829	hsa-miR-4731-3p	CLIP-seq
MIRT2216578	hsa-miR-4760-3p	CLIP-seq
MIRT950834	hsa-miR-4766-5p	CLIP-seq
MIRT950842	hsa-miR-4801	CLIP-seq
MIRT950845	hsa-miR-488	CLIP-seq
MIRT1981607	hsa-miR-513b	CLIP-seq
MIRT950853	hsa-miR-518a-5p	CLIP-seq
MIRT950855	hsa-miR-520d-5p	CLIP-seq
MIRT950856	hsa-miR-524-5p	CLIP-seq
MIRT950858	hsa-miR-527	CLIP-seq
MIRT950859	hsa-miR-548ac	CLIP-seq
MIRT950860	hsa-miR-548d-3p	CLIP-seq
MIRT950863	hsa-miR-548z	CLIP-seq
MIRT2520458	hsa-miR-570	CLIP-seq
MIRT2520459	hsa-miR-590-3p	CLIP-seq
MIRT950870	hsa-miR-605	CLIP-seq
MIRT950871	hsa-miR-607	CLIP-seq
MIRT2520460	hsa-miR-944	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq
MIRT950704	hsa-let-7a	CLIP-seq
MIRT950705	hsa-let-7b	CLIP-seq
MIRT950706	hsa-let-7c	CLIP-seq
MIRT950707	hsa-let-7d	CLIP-seq
MIRT950708	hsa-let-7e	CLIP-seq
MIRT950709	hsa-let-7f	CLIP-seq
MIRT950710	hsa-let-7g	CLIP-seq
MIRT950711	hsa-let-7i	CLIP-seq
MIRT950722	hsa-miR-1305	CLIP-seq
MIRT950736	hsa-miR-202	CLIP-seq
MIRT950751	hsa-miR-3120-3p	CLIP-seq
MIRT2520454	hsa-miR-3145-5p	CLIP-seq
MIRT2679641	hsa-miR-3148	CLIP-seq
MIRT2520455	hsa-miR-3163	CLIP-seq
MIRT950760	hsa-miR-323-3p	CLIP-seq
MIRT2520456	hsa-miR-340	CLIP-seq
MIRT950767	hsa-miR-3647-3p	CLIP-seq
MIRT2679642	hsa-miR-3668	CLIP-seq
MIRT950774	hsa-miR-3682-5p	CLIP-seq
MIRT950784	hsa-miR-3927	CLIP-seq
MIRT2679643	hsa-miR-3978	CLIP-seq
MIRT950807	hsa-miR-4519	CLIP-seq
MIRT2387198	hsa-miR-4666-5p	CLIP-seq
MIRT950825	hsa-miR-4708-3p	CLIP-seq
MIRT950829	hsa-miR-4731-3p	CLIP-seq
MIRT950834	hsa-miR-4766-5p	CLIP-seq
MIRT950842	hsa-miR-4801	CLIP-seq
MIRT950843	hsa-miR-4803	CLIP-seq
MIRT950845	hsa-miR-488	CLIP-seq
MIRT950853	hsa-miR-518a-5p	CLIP-seq
MIRT950855	hsa-miR-520d-5p	CLIP-seq
MIRT950856	hsa-miR-524-5p	CLIP-seq
MIRT950858	hsa-miR-527	CLIP-seq
MIRT950859	hsa-miR-548ac	CLIP-seq
MIRT950860	hsa-miR-548d-3p	CLIP-seq
MIRT950863	hsa-miR-548z	CLIP-seq
MIRT2520458	hsa-miR-570	CLIP-seq
MIRT2520459	hsa-miR-590-3p	CLIP-seq
MIRT950870	hsa-miR-605	CLIP-seq
MIRT2520460	hsa-miR-944	CLIP-seq
MIRT950887	hsa-miR-98	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
BRCA1	Repression	17096023
E2F1	Activation	16107498

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	9501179
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	TAS	9501179
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	9501179
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	9501179
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 17062573, 20211142, 21516116, 24981860, 25416956, 25609649, 26871637, 27705803, 28514442, 32296183, 33961781, 35512704
GO:0005634	Component	Nucleus	IDA	17001316
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0046983	Function	Protein dimerization activity	IEA
GO:0071339	Component	MLL1 complex	IDA	15960975
GO:0090575	Component	RNA polymerase II transcription regulator complex	IBA
GO:0090575	Component	RNA polymerase II transcription regulator complex	IDA	9501179

MIM	HGNC	e!Ensembl
602944	3120	ENSG00000169016

Protein

UniProt ID

O75461

Protein name

Transcription factor E2F6 (E2F-6)

Protein function

Inhibitor of E2F-dependent transcription (PubMed:9501179, PubMed:9689056, PubMed:9704927). Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' (PubMed:9501179). Has a preference for the 5'-TTTCCCGC-3' E2F

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02319	E2F_TDP	64 → 128	E2F/DP family winged-helix DNA-binding domain	Domain
PF16421	E2F_CC-MB	143 → 237	E2F transcription factor CC-MB domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen. {ECO:0000269|PubMed:9689056}.

Sequence

MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVSMRKALKVK
RPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKS
KNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERL
AYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQ
GQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN

Sequence length

281

Interactions

View interactions

	KEGG		Reactome
	Polycomb repressive complex		G1/S-Specific Transcription Transcriptional Regulation by E2F6

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Astrocytoma	Astrocytoma	N/A	N/A	GWAS
Glioblastoma	Glioblastoma	Taken together, these data showed that E2F6 is a vulnerability related to TMZ?resistant GBM and that inhibition of E2F6 could be a promising therapeutic strategy for TMZ?resistant GBM.	31508283	CBGDA, GWAS
Heart Failure	Heart failure	N/A	N/A	GWAS
Hypertrophic cardiomyopathy	Hypertrophic cardiomyopathy	N/A	N/A	GWAS

Show/Hide Text Mining Associations (25)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	24564251
Brain Neoplasms	Stimulate	33381564
Carcinogenesis	Associate	19430707
Carcinoma	Associate	31467233
Carcinoma Hepatocellular	Associate	27818995, 35844791
Carcinoma Non Small Cell Lung	Stimulate	24564251
Carcinoma Non Small Cell Lung	Associate	34588094
Carcinoma Renal Cell	Associate	30338798
Carcinoma Squamous Cell	Associate	24564251
Glioblastoma	Stimulate	38071912
Glioma	Associate	33381564, 38071912
Graft vs Host Disease	Associate	35401560
Heart Defects Congenital	Associate	28336264
Leukemia Erythroblastic Acute	Associate	28657656
Lymphoma Follicular	Associate	21240256
Neoplasm Metastasis	Associate	35844791
Neoplasms	Inhibit	12909625
Neoplasms	Associate	17908821, 37915049, 38071912
Neoplasms	Stimulate	33381564
Ovarian Neoplasms	Associate	25545504, 35216394
Pancreatic Neoplasms	Associate	34799547
Prostatic Neoplasms	Associate	39318189, 39473405
Squamous Cell Carcinoma of Head and Neck	Associate	36855110
Stomach Neoplasms	Associate	30487158
Uterine Cervical Neoplasms	Associate	31682716

E2F6 (E2F transcription factor 6)