Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1846
Gene name Gene Name - the full gene name approved by the HGNC.	Dual specificity phosphatase 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DUSP4
Synonyms (NCBI Gene) Gene synonyms aliases	HVH2, MKP-2, MKP2, TYP
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8p12
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regu

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miRTarBase ID	miRNA	Experiments	Reference
MIRT437484	hsa-miR-185-5p	Luciferase reporter assay, qRT-PCR, Western blot	24014023
MIRT650480	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT650478	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT650479	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT650477	hsa-miR-4287	HITS-CLIP	23824327
MIRT650476	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650475	hsa-miR-4290	HITS-CLIP	23824327
MIRT650474	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT650473	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT650472	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT650471	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT650470	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT650469	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT650468	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT650467	hsa-miR-4705	HITS-CLIP	23824327
MIRT650466	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT650465	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT532325	hsa-miR-606	PAR-CLIP	22012620
MIRT532324	hsa-miR-3529-3p	PAR-CLIP	22012620
MIRT532323	hsa-miR-302b-5p	PAR-CLIP	22012620
MIRT532322	hsa-miR-302d-5p	PAR-CLIP	22012620
MIRT447935	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT447933	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT447934	hsa-miR-3148	PAR-CLIP	22100165
MIRT447932	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT447931	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT447930	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT447935	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT447933	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT447934	hsa-miR-3148	PAR-CLIP	22100165
MIRT447932	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT447931	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT447930	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT731390	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25877859
MIRT731390	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25877859
MIRT650480	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT650478	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT650479	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT650477	hsa-miR-4287	HITS-CLIP	23824327
MIRT650476	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650475	hsa-miR-4290	HITS-CLIP	23824327
MIRT650474	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT650473	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT650472	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT650471	hsa-miR-3157-3p	HITS-CLIP	23824327
MIRT650470	hsa-miR-874-3p	HITS-CLIP	23824327
MIRT650469	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT650468	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT650467	hsa-miR-4705	HITS-CLIP	23824327
MIRT650466	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT650465	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT532325	hsa-miR-606	PAR-CLIP	22012620
MIRT532324	hsa-miR-3529-3p	PAR-CLIP	22012620
MIRT532323	hsa-miR-302b-5p	PAR-CLIP	22012620
MIRT532322	hsa-miR-302d-5p	PAR-CLIP	22012620
MIRT447935	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT447933	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT447934	hsa-miR-3148	PAR-CLIP	22100165
MIRT447932	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT447931	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT447930	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT447935	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT447933	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT447934	hsa-miR-3148	PAR-CLIP	22100165
MIRT447932	hsa-miR-1249-5p	PAR-CLIP	22100165
MIRT447931	hsa-miR-6797-5p	PAR-CLIP	22100165
MIRT447930	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT947967	hsa-let-7a	CLIP-seq
MIRT947968	hsa-let-7b	CLIP-seq
MIRT947969	hsa-let-7c	CLIP-seq
MIRT947970	hsa-let-7d	CLIP-seq
MIRT947971	hsa-let-7e	CLIP-seq
MIRT947972	hsa-let-7f	CLIP-seq
MIRT947973	hsa-let-7g	CLIP-seq
MIRT947974	hsa-let-7i	CLIP-seq
MIRT947975	hsa-miR-1226	CLIP-seq
MIRT947976	hsa-miR-1286	CLIP-seq
MIRT947977	hsa-miR-1289	CLIP-seq
MIRT947978	hsa-miR-1293	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT947980	hsa-miR-139-5p	CLIP-seq
MIRT947981	hsa-miR-145	CLIP-seq
MIRT947982	hsa-miR-149	CLIP-seq
MIRT947983	hsa-miR-188-5p	CLIP-seq
MIRT947984	hsa-miR-202	CLIP-seq
MIRT947985	hsa-miR-204	CLIP-seq
MIRT947986	hsa-miR-211	CLIP-seq
MIRT947987	hsa-miR-2110	CLIP-seq
MIRT947988	hsa-miR-28-5p	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT947990	hsa-miR-3122	CLIP-seq
MIRT947991	hsa-miR-3127-5p	CLIP-seq
MIRT947992	hsa-miR-3139	CLIP-seq
MIRT947993	hsa-miR-3147	CLIP-seq
MIRT947994	hsa-miR-3169	CLIP-seq
MIRT947995	hsa-miR-3176	CLIP-seq
MIRT947996	hsa-miR-3180-5p	CLIP-seq
MIRT947997	hsa-miR-320a	CLIP-seq
MIRT947998	hsa-miR-320b	CLIP-seq
MIRT947999	hsa-miR-320c	CLIP-seq
MIRT948000	hsa-miR-320d	CLIP-seq
MIRT948001	hsa-miR-320e	CLIP-seq
MIRT948002	hsa-miR-342-5p	CLIP-seq
MIRT948003	hsa-miR-34c-3p	CLIP-seq
MIRT948004	hsa-miR-3609	CLIP-seq
MIRT948005	hsa-miR-361-3p	CLIP-seq
MIRT948006	hsa-miR-3652	CLIP-seq
MIRT948007	hsa-miR-3662	CLIP-seq
MIRT948008	hsa-miR-3668	CLIP-seq
MIRT948009	hsa-miR-3675-3p	CLIP-seq
MIRT948010	hsa-miR-3675-5p	CLIP-seq
MIRT948011	hsa-miR-3913-5p	CLIP-seq
MIRT948012	hsa-miR-3922-3p	CLIP-seq
MIRT948013	hsa-miR-3924	CLIP-seq
MIRT948014	hsa-miR-3941	CLIP-seq
MIRT948015	hsa-miR-4271	CLIP-seq
MIRT948016	hsa-miR-4283	CLIP-seq
MIRT948017	hsa-miR-4300	CLIP-seq
MIRT948018	hsa-miR-4316	CLIP-seq
MIRT948019	hsa-miR-4426	CLIP-seq
MIRT948020	hsa-miR-4428	CLIP-seq
MIRT948021	hsa-miR-4429	CLIP-seq
MIRT948022	hsa-miR-4430	CLIP-seq
MIRT948023	hsa-miR-4433	CLIP-seq
MIRT948024	hsa-miR-4438	CLIP-seq
MIRT948025	hsa-miR-4458	CLIP-seq
MIRT948026	hsa-miR-4483	CLIP-seq
MIRT948027	hsa-miR-4489	CLIP-seq
MIRT948028	hsa-miR-4500	CLIP-seq
MIRT948029	hsa-miR-4505	CLIP-seq
MIRT948030	hsa-miR-452	CLIP-seq
MIRT948031	hsa-miR-4532	CLIP-seq
MIRT948032	hsa-miR-4533	CLIP-seq
MIRT948033	hsa-miR-4633-3p	CLIP-seq
MIRT948034	hsa-miR-4638-5p	CLIP-seq
MIRT948035	hsa-miR-4639-3p	CLIP-seq
MIRT948036	hsa-miR-4647	CLIP-seq
MIRT948037	hsa-miR-4651	CLIP-seq
MIRT948038	hsa-miR-4659a-5p	CLIP-seq
MIRT948039	hsa-miR-4659b-5p	CLIP-seq
MIRT948040	hsa-miR-466	CLIP-seq
MIRT948041	hsa-miR-4661-3p	CLIP-seq
MIRT948042	hsa-miR-4662b	CLIP-seq
MIRT948043	hsa-miR-4663	CLIP-seq
MIRT948044	hsa-miR-4664-5p	CLIP-seq
MIRT948045	hsa-miR-4672	CLIP-seq
MIRT948046	hsa-miR-4676-3p	CLIP-seq
MIRT948047	hsa-miR-4676-5p	CLIP-seq
MIRT948048	hsa-miR-4699-3p	CLIP-seq
MIRT948049	hsa-miR-4700-3p	CLIP-seq
MIRT948050	hsa-miR-4714-5p	CLIP-seq
MIRT948051	hsa-miR-4720-3p	CLIP-seq
MIRT948052	hsa-miR-4725-3p	CLIP-seq
MIRT948053	hsa-miR-4728-3p	CLIP-seq
MIRT948054	hsa-miR-4731-3p	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT948056	hsa-miR-4733-3p	CLIP-seq
MIRT948057	hsa-miR-4738-3p	CLIP-seq
MIRT948058	hsa-miR-4747-5p	CLIP-seq
MIRT948059	hsa-miR-4757-5p	CLIP-seq
MIRT948060	hsa-miR-4766-3p	CLIP-seq
MIRT948061	hsa-miR-4766-5p	CLIP-seq
MIRT948062	hsa-miR-4776-3p	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT948064	hsa-miR-4794	CLIP-seq
MIRT948065	hsa-miR-4795-3p	CLIP-seq
MIRT948066	hsa-miR-4801	CLIP-seq
MIRT948067	hsa-miR-4804-3p	CLIP-seq
MIRT948068	hsa-miR-498	CLIP-seq
MIRT948069	hsa-miR-5095	CLIP-seq
MIRT948070	hsa-miR-510	CLIP-seq
MIRT948071	hsa-miR-513a-3p	CLIP-seq
MIRT948072	hsa-miR-522	CLIP-seq
MIRT948073	hsa-miR-539	CLIP-seq
MIRT948074	hsa-miR-548ah	CLIP-seq
MIRT948075	hsa-miR-548p	CLIP-seq
MIRT948076	hsa-miR-548t	CLIP-seq
MIRT948077	hsa-miR-570	CLIP-seq
MIRT948078	hsa-miR-575	CLIP-seq
MIRT948079	hsa-miR-579	CLIP-seq
MIRT948080	hsa-miR-603	CLIP-seq
MIRT948081	hsa-miR-608	CLIP-seq
MIRT948082	hsa-miR-629	CLIP-seq
MIRT948083	hsa-miR-630	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT948085	hsa-miR-664	CLIP-seq
MIRT948086	hsa-miR-708	CLIP-seq
MIRT948087	hsa-miR-874	CLIP-seq
MIRT948088	hsa-miR-920	CLIP-seq
MIRT948089	hsa-miR-939	CLIP-seq
MIRT948090	hsa-miR-942	CLIP-seq
MIRT948091	hsa-miR-98	CLIP-seq
MIRT947967	hsa-let-7a	CLIP-seq
MIRT947968	hsa-let-7b	CLIP-seq
MIRT947969	hsa-let-7c	CLIP-seq
MIRT947970	hsa-let-7d	CLIP-seq
MIRT947971	hsa-let-7e	CLIP-seq
MIRT947972	hsa-let-7f	CLIP-seq
MIRT947973	hsa-let-7g	CLIP-seq
MIRT947974	hsa-let-7i	CLIP-seq
MIRT948092	hsa-miR-1200	CLIP-seq
MIRT948093	hsa-miR-1228	CLIP-seq
MIRT948094	hsa-miR-1297	CLIP-seq
MIRT948095	hsa-miR-1302	CLIP-seq
MIRT948096	hsa-miR-133a	CLIP-seq
MIRT948097	hsa-miR-133b	CLIP-seq
MIRT948098	hsa-miR-135a	CLIP-seq
MIRT948099	hsa-miR-135b	CLIP-seq
MIRT947982	hsa-miR-149	CLIP-seq
MIRT947983	hsa-miR-188-5p	CLIP-seq
MIRT948100	hsa-miR-1915	CLIP-seq
MIRT948101	hsa-miR-200b	CLIP-seq
MIRT948102	hsa-miR-200c	CLIP-seq
MIRT947984	hsa-miR-202	CLIP-seq
MIRT947985	hsa-miR-204	CLIP-seq
MIRT947986	hsa-miR-211	CLIP-seq
MIRT948103	hsa-miR-26a	CLIP-seq
MIRT948104	hsa-miR-26b	CLIP-seq
MIRT948105	hsa-miR-2964a-3p	CLIP-seq
MIRT948106	hsa-miR-3065-5p	CLIP-seq
MIRT948107	hsa-miR-3119	CLIP-seq
MIRT947990	hsa-miR-3122	CLIP-seq
MIRT948108	hsa-miR-3140-3p	CLIP-seq
MIRT947993	hsa-miR-3147	CLIP-seq
MIRT948109	hsa-miR-3153	CLIP-seq
MIRT948110	hsa-miR-3157-5p	CLIP-seq
MIRT948111	hsa-miR-3192	CLIP-seq
MIRT948112	hsa-miR-3194-3p	CLIP-seq
MIRT948113	hsa-miR-3199	CLIP-seq
MIRT947997	hsa-miR-320a	CLIP-seq
MIRT947998	hsa-miR-320b	CLIP-seq
MIRT947999	hsa-miR-320c	CLIP-seq
MIRT948000	hsa-miR-320d	CLIP-seq
MIRT948001	hsa-miR-320e	CLIP-seq
MIRT948114	hsa-miR-329	CLIP-seq
MIRT948115	hsa-miR-339-5p	CLIP-seq
MIRT948003	hsa-miR-34c-3p	CLIP-seq
MIRT948005	hsa-miR-361-3p	CLIP-seq
MIRT948116	hsa-miR-3622a-3p	CLIP-seq
MIRT948117	hsa-miR-3622b-3p	CLIP-seq
MIRT948118	hsa-miR-362-3p	CLIP-seq
MIRT948119	hsa-miR-3646	CLIP-seq
MIRT948007	hsa-miR-3662	CLIP-seq
MIRT948008	hsa-miR-3668	CLIP-seq
MIRT948010	hsa-miR-3675-5p	CLIP-seq
MIRT948120	hsa-miR-3679-3p	CLIP-seq
MIRT948121	hsa-miR-3682-5p	CLIP-seq
MIRT948122	hsa-miR-3692	CLIP-seq
MIRT948011	hsa-miR-3913-5p	CLIP-seq
MIRT948013	hsa-miR-3924	CLIP-seq
MIRT948014	hsa-miR-3941	CLIP-seq
MIRT948123	hsa-miR-4268	CLIP-seq
MIRT948016	hsa-miR-4283	CLIP-seq
MIRT948124	hsa-miR-429	CLIP-seq
MIRT948125	hsa-miR-4298	CLIP-seq
MIRT948017	hsa-miR-4300	CLIP-seq
MIRT948126	hsa-miR-4314	CLIP-seq
MIRT948018	hsa-miR-4316	CLIP-seq
MIRT948127	hsa-miR-4324	CLIP-seq
MIRT948019	hsa-miR-4426	CLIP-seq
MIRT948021	hsa-miR-4429	CLIP-seq
MIRT948023	hsa-miR-4433	CLIP-seq
MIRT948025	hsa-miR-4458	CLIP-seq
MIRT948128	hsa-miR-4465	CLIP-seq
MIRT948129	hsa-miR-4487	CLIP-seq
MIRT948027	hsa-miR-4489	CLIP-seq
MIRT948028	hsa-miR-4500	CLIP-seq
MIRT948130	hsa-miR-4540	CLIP-seq
MIRT948131	hsa-miR-4636	CLIP-seq
MIRT948035	hsa-miR-4639-3p	CLIP-seq
MIRT948132	hsa-miR-4646-5p	CLIP-seq
MIRT948036	hsa-miR-4647	CLIP-seq
MIRT948133	hsa-miR-4648	CLIP-seq
MIRT948134	hsa-miR-4654	CLIP-seq
MIRT948040	hsa-miR-466	CLIP-seq
MIRT948042	hsa-miR-4662b	CLIP-seq
MIRT948043	hsa-miR-4663	CLIP-seq
MIRT948045	hsa-miR-4672	CLIP-seq
MIRT948047	hsa-miR-4676-5p	CLIP-seq
MIRT948135	hsa-miR-4682	CLIP-seq
MIRT948136	hsa-miR-4685-5p	CLIP-seq
MIRT948137	hsa-miR-4698	CLIP-seq
MIRT948048	hsa-miR-4699-3p	CLIP-seq
MIRT948138	hsa-miR-4699-5p	CLIP-seq
MIRT948139	hsa-miR-4704-3p	CLIP-seq
MIRT948050	hsa-miR-4714-5p	CLIP-seq
MIRT948051	hsa-miR-4720-3p	CLIP-seq
MIRT948053	hsa-miR-4728-3p	CLIP-seq
MIRT948054	hsa-miR-4731-3p	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT948061	hsa-miR-4766-5p	CLIP-seq
MIRT948140	hsa-miR-4769-5p	CLIP-seq
MIRT948065	hsa-miR-4795-3p	CLIP-seq
MIRT948066	hsa-miR-4801	CLIP-seq
MIRT948067	hsa-miR-4804-3p	CLIP-seq
MIRT948141	hsa-miR-490-3p	CLIP-seq
MIRT948068	hsa-miR-498	CLIP-seq
MIRT948070	hsa-miR-510	CLIP-seq
MIRT948142	hsa-miR-511	CLIP-seq
MIRT948071	hsa-miR-513a-3p	CLIP-seq
MIRT948072	hsa-miR-522	CLIP-seq
MIRT948073	hsa-miR-539	CLIP-seq
MIRT948143	hsa-miR-541	CLIP-seq
MIRT948144	hsa-miR-544b	CLIP-seq
MIRT948145	hsa-miR-548aa	CLIP-seq
MIRT948146	hsa-miR-548ac	CLIP-seq
MIRT948147	hsa-miR-548ae	CLIP-seq
MIRT948148	hsa-miR-548aj	CLIP-seq
MIRT948149	hsa-miR-548am	CLIP-seq
MIRT948150	hsa-miR-548d-3p	CLIP-seq
MIRT948151	hsa-miR-548x	CLIP-seq
MIRT948152	hsa-miR-548z	CLIP-seq
MIRT948153	hsa-miR-554	CLIP-seq
MIRT948077	hsa-miR-570	CLIP-seq
MIRT948078	hsa-miR-575	CLIP-seq
MIRT948154	hsa-miR-593	CLIP-seq
MIRT948155	hsa-miR-622	CLIP-seq
MIRT948083	hsa-miR-630	CLIP-seq
MIRT948156	hsa-miR-654-5p	CLIP-seq
MIRT948157	hsa-miR-760	CLIP-seq
MIRT948087	hsa-miR-874	CLIP-seq
MIRT948158	hsa-miR-892a	CLIP-seq
MIRT948088	hsa-miR-920	CLIP-seq
MIRT948090	hsa-miR-942	CLIP-seq
MIRT948091	hsa-miR-98	CLIP-seq
MIRT1548078	hsa-miR-4421	CLIP-seq
MIRT1980888	hsa-miR-122	CLIP-seq
MIRT1980889	hsa-miR-1283	CLIP-seq
MIRT947977	hsa-miR-1289	CLIP-seq
MIRT948096	hsa-miR-133a	CLIP-seq
MIRT948097	hsa-miR-133b	CLIP-seq
MIRT948098	hsa-miR-135a	CLIP-seq
MIRT948099	hsa-miR-135b	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT1980890	hsa-miR-224	CLIP-seq
MIRT1980891	hsa-miR-2355-5p	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT948106	hsa-miR-3065-5p	CLIP-seq
MIRT948108	hsa-miR-3140-3p	CLIP-seq
MIRT947993	hsa-miR-3147	CLIP-seq
MIRT948111	hsa-miR-3192	CLIP-seq
MIRT1980892	hsa-miR-3198	CLIP-seq
MIRT947997	hsa-miR-320a	CLIP-seq
MIRT947998	hsa-miR-320b	CLIP-seq
MIRT947999	hsa-miR-320c	CLIP-seq
MIRT948000	hsa-miR-320d	CLIP-seq
MIRT948001	hsa-miR-320e	CLIP-seq
MIRT1980893	hsa-miR-3619-3p	CLIP-seq
MIRT1980894	hsa-miR-3653	CLIP-seq
MIRT1980895	hsa-miR-3658	CLIP-seq
MIRT1980896	hsa-miR-3659	CLIP-seq
MIRT948007	hsa-miR-3662	CLIP-seq
MIRT948008	hsa-miR-3668	CLIP-seq
MIRT948120	hsa-miR-3679-3p	CLIP-seq
MIRT1980897	hsa-miR-3688-5p	CLIP-seq
MIRT948122	hsa-miR-3692	CLIP-seq
MIRT1980898	hsa-miR-382	CLIP-seq
MIRT948013	hsa-miR-3924	CLIP-seq
MIRT1980899	hsa-miR-4255	CLIP-seq
MIRT1980900	hsa-miR-4292	CLIP-seq
MIRT1980901	hsa-miR-4308	CLIP-seq
MIRT1980902	hsa-miR-4309	CLIP-seq
MIRT948126	hsa-miR-4314	CLIP-seq
MIRT1548078	hsa-miR-4421	CLIP-seq
MIRT948019	hsa-miR-4426	CLIP-seq
MIRT948021	hsa-miR-4429	CLIP-seq
MIRT1980903	hsa-miR-4470	CLIP-seq
MIRT948032	hsa-miR-4533	CLIP-seq
MIRT948132	hsa-miR-4646-5p	CLIP-seq
MIRT948036	hsa-miR-4647	CLIP-seq
MIRT1980904	hsa-miR-4652-3p	CLIP-seq
MIRT948041	hsa-miR-4661-3p	CLIP-seq
MIRT948042	hsa-miR-4662b	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT948065	hsa-miR-4795-3p	CLIP-seq
MIRT948142	hsa-miR-511	CLIP-seq
MIRT1980905	hsa-miR-591	CLIP-seq
MIRT1980906	hsa-miR-604	CLIP-seq
MIRT1980907	hsa-miR-626	CLIP-seq
MIRT948082	hsa-miR-629	CLIP-seq
MIRT948083	hsa-miR-630	CLIP-seq
MIRT1980908	hsa-miR-642a	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT1980909	hsa-miR-647	CLIP-seq
MIRT1980910	hsa-miR-670	CLIP-seq
MIRT948122	hsa-miR-3692	CLIP-seq
MIRT1980908	hsa-miR-642a	CLIP-seq
MIRT947967	hsa-let-7a	CLIP-seq
MIRT947968	hsa-let-7b	CLIP-seq
MIRT947969	hsa-let-7c	CLIP-seq
MIRT947970	hsa-let-7d	CLIP-seq
MIRT947971	hsa-let-7e	CLIP-seq
MIRT947972	hsa-let-7f	CLIP-seq
MIRT947973	hsa-let-7g	CLIP-seq
MIRT947974	hsa-let-7i	CLIP-seq
MIRT2215894	hsa-miR-105	CLIP-seq
MIRT2215895	hsa-miR-1184	CLIP-seq
MIRT2215896	hsa-miR-1205	CLIP-seq
MIRT2215897	hsa-miR-1206	CLIP-seq
MIRT2215898	hsa-miR-1207-3p	CLIP-seq
MIRT1980888	hsa-miR-122	CLIP-seq
MIRT2215899	hsa-miR-1225-3p	CLIP-seq
MIRT947975	hsa-miR-1226	CLIP-seq
MIRT948093	hsa-miR-1228	CLIP-seq
MIRT2215900	hsa-miR-1233	CLIP-seq
MIRT2215901	hsa-miR-1267	CLIP-seq
MIRT2215902	hsa-miR-1273f	CLIP-seq
MIRT1980889	hsa-miR-1283	CLIP-seq
MIRT947976	hsa-miR-1286	CLIP-seq
MIRT947977	hsa-miR-1289	CLIP-seq
MIRT947978	hsa-miR-1293	CLIP-seq
MIRT2215903	hsa-miR-1306	CLIP-seq
MIRT2215904	hsa-miR-1322	CLIP-seq
MIRT948098	hsa-miR-135a	CLIP-seq
MIRT948099	hsa-miR-135b	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT2215905	hsa-miR-143	CLIP-seq
MIRT2215906	hsa-miR-1470	CLIP-seq
MIRT947982	hsa-miR-149	CLIP-seq
MIRT2215907	hsa-miR-183	CLIP-seq
MIRT947983	hsa-miR-188-5p	CLIP-seq
MIRT2215908	hsa-miR-192	CLIP-seq
MIRT948101	hsa-miR-200b	CLIP-seq
MIRT948102	hsa-miR-200c	CLIP-seq
MIRT947984	hsa-miR-202	CLIP-seq
MIRT947985	hsa-miR-204	CLIP-seq
MIRT2215909	hsa-miR-205	CLIP-seq
MIRT2215910	hsa-miR-2054	CLIP-seq
MIRT947986	hsa-miR-211	CLIP-seq
MIRT947987	hsa-miR-2110	CLIP-seq
MIRT2215911	hsa-miR-215	CLIP-seq
MIRT1980891	hsa-miR-2355-5p	CLIP-seq
MIRT948105	hsa-miR-2964a-3p	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT948106	hsa-miR-3065-5p	CLIP-seq
MIRT948107	hsa-miR-3119	CLIP-seq
MIRT947990	hsa-miR-3122	CLIP-seq
MIRT2215912	hsa-miR-3130-3p	CLIP-seq
MIRT2215913	hsa-miR-3134	CLIP-seq
MIRT948108	hsa-miR-3140-3p	CLIP-seq
MIRT947993	hsa-miR-3147	CLIP-seq
MIRT948109	hsa-miR-3153	CLIP-seq
MIRT948110	hsa-miR-3157-5p	CLIP-seq
MIRT2215914	hsa-miR-3158-5p	CLIP-seq
MIRT947994	hsa-miR-3169	CLIP-seq
MIRT947995	hsa-miR-3176	CLIP-seq
MIRT947996	hsa-miR-3180-5p	CLIP-seq
MIRT2215915	hsa-miR-3187-3p	CLIP-seq
MIRT948111	hsa-miR-3192	CLIP-seq
MIRT948112	hsa-miR-3194-3p	CLIP-seq
MIRT1980892	hsa-miR-3198	CLIP-seq
MIRT948113	hsa-miR-3199	CLIP-seq
MIRT947997	hsa-miR-320a	CLIP-seq
MIRT947998	hsa-miR-320b	CLIP-seq
MIRT947999	hsa-miR-320c	CLIP-seq
MIRT948000	hsa-miR-320d	CLIP-seq
MIRT948001	hsa-miR-320e	CLIP-seq
MIRT948114	hsa-miR-329	CLIP-seq
MIRT2215916	hsa-miR-335	CLIP-seq
MIRT948002	hsa-miR-342-5p	CLIP-seq
MIRT948003	hsa-miR-34c-3p	CLIP-seq
MIRT2215917	hsa-miR-3591-5p	CLIP-seq
MIRT948004	hsa-miR-3609	CLIP-seq
MIRT1980893	hsa-miR-3619-3p	CLIP-seq
MIRT948116	hsa-miR-3622a-3p	CLIP-seq
MIRT948117	hsa-miR-3622b-3p	CLIP-seq
MIRT948118	hsa-miR-362-3p	CLIP-seq
MIRT948006	hsa-miR-3652	CLIP-seq
MIRT1980896	hsa-miR-3659	CLIP-seq
MIRT948007	hsa-miR-3662	CLIP-seq
MIRT2215918	hsa-miR-3663-3p	CLIP-seq
MIRT2215919	hsa-miR-3665	CLIP-seq
MIRT948008	hsa-miR-3668	CLIP-seq
MIRT948010	hsa-miR-3675-5p	CLIP-seq
MIRT2215920	hsa-miR-3680	CLIP-seq
MIRT948121	hsa-miR-3682-5p	CLIP-seq
MIRT1980897	hsa-miR-3688-5p	CLIP-seq
MIRT948122	hsa-miR-3692	CLIP-seq
MIRT1980898	hsa-miR-382	CLIP-seq
MIRT2215921	hsa-miR-3913-3p	CLIP-seq
MIRT948011	hsa-miR-3913-5p	CLIP-seq
MIRT948012	hsa-miR-3922-3p	CLIP-seq
MIRT2215922	hsa-miR-3926	CLIP-seq
MIRT948014	hsa-miR-3941	CLIP-seq
MIRT2215923	hsa-miR-409-5p	CLIP-seq
MIRT1980899	hsa-miR-4255	CLIP-seq
MIRT2215924	hsa-miR-4264	CLIP-seq
MIRT948015	hsa-miR-4271	CLIP-seq
MIRT2215925	hsa-miR-4280	CLIP-seq
MIRT948016	hsa-miR-4283	CLIP-seq
MIRT948124	hsa-miR-429	CLIP-seq
MIRT1980900	hsa-miR-4292	CLIP-seq
MIRT2215926	hsa-miR-4294	CLIP-seq
MIRT948017	hsa-miR-4300	CLIP-seq
MIRT1980901	hsa-miR-4308	CLIP-seq
MIRT1980902	hsa-miR-4309	CLIP-seq
MIRT2215927	hsa-miR-4312	CLIP-seq
MIRT948126	hsa-miR-4314	CLIP-seq
MIRT2215928	hsa-miR-4420	CLIP-seq
MIRT1548078	hsa-miR-4421	CLIP-seq
MIRT948019	hsa-miR-4426	CLIP-seq
MIRT948020	hsa-miR-4428	CLIP-seq
MIRT948021	hsa-miR-4429	CLIP-seq
MIRT948022	hsa-miR-4430	CLIP-seq
MIRT948023	hsa-miR-4433	CLIP-seq
MIRT2215929	hsa-miR-4435	CLIP-seq
MIRT948024	hsa-miR-4438	CLIP-seq
MIRT2215930	hsa-miR-4453	CLIP-seq
MIRT948025	hsa-miR-4458	CLIP-seq
MIRT2215931	hsa-miR-4469	CLIP-seq
MIRT2215932	hsa-miR-4475	CLIP-seq
MIRT948026	hsa-miR-4483	CLIP-seq
MIRT948027	hsa-miR-4489	CLIP-seq
MIRT948028	hsa-miR-4500	CLIP-seq
MIRT948029	hsa-miR-4505	CLIP-seq
MIRT2215933	hsa-miR-4517	CLIP-seq
MIRT948030	hsa-miR-452	CLIP-seq
MIRT948031	hsa-miR-4532	CLIP-seq
MIRT948032	hsa-miR-4533	CLIP-seq
MIRT2215934	hsa-miR-4538	CLIP-seq
MIRT948033	hsa-miR-4633-3p	CLIP-seq
MIRT948034	hsa-miR-4638-5p	CLIP-seq
MIRT948035	hsa-miR-4639-3p	CLIP-seq
MIRT948132	hsa-miR-4646-5p	CLIP-seq
MIRT948036	hsa-miR-4647	CLIP-seq
MIRT948133	hsa-miR-4648	CLIP-seq
MIRT948037	hsa-miR-4651	CLIP-seq
MIRT1980904	hsa-miR-4652-3p	CLIP-seq
MIRT948134	hsa-miR-4654	CLIP-seq
MIRT948040	hsa-miR-466	CLIP-seq
MIRT948041	hsa-miR-4661-3p	CLIP-seq
MIRT948042	hsa-miR-4662b	CLIP-seq
MIRT948044	hsa-miR-4664-5p	CLIP-seq
MIRT2215935	hsa-miR-4667-3p	CLIP-seq
MIRT948045	hsa-miR-4672	CLIP-seq
MIRT948046	hsa-miR-4676-3p	CLIP-seq
MIRT948048	hsa-miR-4699-3p	CLIP-seq
MIRT948049	hsa-miR-4700-3p	CLIP-seq
MIRT2215936	hsa-miR-4701-5p	CLIP-seq
MIRT948139	hsa-miR-4704-3p	CLIP-seq
MIRT2215937	hsa-miR-4708-5p	CLIP-seq
MIRT948050	hsa-miR-4714-5p	CLIP-seq
MIRT948051	hsa-miR-4720-3p	CLIP-seq
MIRT948052	hsa-miR-4725-3p	CLIP-seq
MIRT948054	hsa-miR-4731-3p	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT948056	hsa-miR-4733-3p	CLIP-seq
MIRT2215938	hsa-miR-4733-5p	CLIP-seq
MIRT948057	hsa-miR-4738-3p	CLIP-seq
MIRT948059	hsa-miR-4757-5p	CLIP-seq
MIRT948061	hsa-miR-4766-5p	CLIP-seq
MIRT948140	hsa-miR-4769-5p	CLIP-seq
MIRT2215939	hsa-miR-4770	CLIP-seq
MIRT2215940	hsa-miR-4781-3p	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT948064	hsa-miR-4794	CLIP-seq
MIRT948065	hsa-miR-4795-3p	CLIP-seq
MIRT2215941	hsa-miR-4797-3p	CLIP-seq
MIRT2215942	hsa-miR-4799-5p	CLIP-seq
MIRT948066	hsa-miR-4801	CLIP-seq
MIRT2215943	hsa-miR-4803	CLIP-seq
MIRT948067	hsa-miR-4804-3p	CLIP-seq
MIRT2215944	hsa-miR-489	CLIP-seq
MIRT2215945	hsa-miR-490-5p	CLIP-seq
MIRT2215946	hsa-miR-495	CLIP-seq
MIRT948068	hsa-miR-498	CLIP-seq
MIRT948069	hsa-miR-5095	CLIP-seq
MIRT948070	hsa-miR-510	CLIP-seq
MIRT948142	hsa-miR-511	CLIP-seq
MIRT948071	hsa-miR-513a-3p	CLIP-seq
MIRT2215947	hsa-miR-513a-5p	CLIP-seq
MIRT2215948	hsa-miR-514	CLIP-seq
MIRT2215949	hsa-miR-514b-3p	CLIP-seq
MIRT948072	hsa-miR-522	CLIP-seq
MIRT2215950	hsa-miR-526b	CLIP-seq
MIRT948073	hsa-miR-539	CLIP-seq
MIRT948143	hsa-miR-541	CLIP-seq
MIRT2215951	hsa-miR-544	CLIP-seq
MIRT948145	hsa-miR-548aa	CLIP-seq
MIRT948074	hsa-miR-548ah	CLIP-seq
MIRT2215952	hsa-miR-548s	CLIP-seq
MIRT948076	hsa-miR-548t	CLIP-seq
MIRT948077	hsa-miR-570	CLIP-seq
MIRT2215953	hsa-miR-588	CLIP-seq
MIRT1980905	hsa-miR-591	CLIP-seq
MIRT1980906	hsa-miR-604	CLIP-seq
MIRT2215954	hsa-miR-605	CLIP-seq
MIRT948081	hsa-miR-608	CLIP-seq
MIRT948155	hsa-miR-622	CLIP-seq
MIRT1980908	hsa-miR-642a	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT1980909	hsa-miR-647	CLIP-seq
MIRT2215955	hsa-miR-653	CLIP-seq
MIRT948156	hsa-miR-654-5p	CLIP-seq
MIRT2215956	hsa-miR-657	CLIP-seq
MIRT948085	hsa-miR-664	CLIP-seq
MIRT2215957	hsa-miR-665	CLIP-seq
MIRT1980910	hsa-miR-670	CLIP-seq
MIRT948087	hsa-miR-874	CLIP-seq
MIRT948088	hsa-miR-920	CLIP-seq
MIRT948089	hsa-miR-939	CLIP-seq
MIRT948090	hsa-miR-942	CLIP-seq
MIRT948091	hsa-miR-98	CLIP-seq
MIRT1980888	hsa-miR-122	CLIP-seq
MIRT947975	hsa-miR-1226	CLIP-seq
MIRT2215902	hsa-miR-1273f	CLIP-seq
MIRT1980889	hsa-miR-1283	CLIP-seq
MIRT947978	hsa-miR-1293	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT2215905	hsa-miR-143	CLIP-seq
MIRT2387155	hsa-miR-182	CLIP-seq
MIRT1980890	hsa-miR-224	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT948108	hsa-miR-3140-3p	CLIP-seq
MIRT948109	hsa-miR-3153	CLIP-seq
MIRT2387156	hsa-miR-3174	CLIP-seq
MIRT1980892	hsa-miR-3198	CLIP-seq
MIRT948001	hsa-miR-320e	CLIP-seq
MIRT948002	hsa-miR-342-5p	CLIP-seq
MIRT2387157	hsa-miR-3620	CLIP-seq
MIRT1980896	hsa-miR-3659	CLIP-seq
MIRT948122	hsa-miR-3692	CLIP-seq
MIRT1980898	hsa-miR-382	CLIP-seq
MIRT1980899	hsa-miR-4255	CLIP-seq
MIRT1980900	hsa-miR-4292	CLIP-seq
MIRT1980901	hsa-miR-4308	CLIP-seq
MIRT1980902	hsa-miR-4309	CLIP-seq
MIRT948026	hsa-miR-4483	CLIP-seq
MIRT948037	hsa-miR-4651	CLIP-seq
MIRT1980904	hsa-miR-4652-3p	CLIP-seq
MIRT948044	hsa-miR-4664-5p	CLIP-seq
MIRT948048	hsa-miR-4699-3p	CLIP-seq
MIRT2215937	hsa-miR-4708-5p	CLIP-seq
MIRT948054	hsa-miR-4731-3p	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT948056	hsa-miR-4733-3p	CLIP-seq
MIRT948057	hsa-miR-4738-3p	CLIP-seq
MIRT2215939	hsa-miR-4770	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT948065	hsa-miR-4795-3p	CLIP-seq
MIRT948066	hsa-miR-4801	CLIP-seq
MIRT2387158	hsa-miR-513c	CLIP-seq
MIRT2387159	hsa-miR-514b-5p	CLIP-seq
MIRT1980906	hsa-miR-604	CLIP-seq
MIRT948081	hsa-miR-608	CLIP-seq
MIRT948082	hsa-miR-629	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT1980909	hsa-miR-647	CLIP-seq
MIRT1980910	hsa-miR-670	CLIP-seq
MIRT948087	hsa-miR-874	CLIP-seq
MIRT2387160	hsa-miR-921	CLIP-seq
MIRT2215906	hsa-miR-1470	CLIP-seq
MIRT948110	hsa-miR-3157-5p	CLIP-seq
MIRT948113	hsa-miR-3199	CLIP-seq
MIRT2215930	hsa-miR-4453	CLIP-seq
MIRT2215931	hsa-miR-4469	CLIP-seq
MIRT948029	hsa-miR-4505	CLIP-seq
MIRT2448612	hsa-miR-4515	CLIP-seq
MIRT2215934	hsa-miR-4538	CLIP-seq
MIRT2215935	hsa-miR-4667-3p	CLIP-seq
MIRT2448613	hsa-miR-4691-3p	CLIP-seq
MIRT2448614	hsa-miR-4755-3p	CLIP-seq
MIRT1980908	hsa-miR-642a	CLIP-seq
MIRT948093	hsa-miR-1228	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT948114	hsa-miR-329	CLIP-seq
MIRT2520139	hsa-miR-3613-3p	CLIP-seq
MIRT948118	hsa-miR-362-3p	CLIP-seq
MIRT1980900	hsa-miR-4292	CLIP-seq
MIRT1980901	hsa-miR-4308	CLIP-seq
MIRT2520140	hsa-miR-4736	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT2520141	hsa-miR-491-3p	CLIP-seq
MIRT1980906	hsa-miR-604	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT1980909	hsa-miR-647	CLIP-seq
MIRT2215956	hsa-miR-657	CLIP-seq
MIRT1980910	hsa-miR-670	CLIP-seq
MIRT948093	hsa-miR-1228	CLIP-seq
MIRT947976	hsa-miR-1286	CLIP-seq
MIRT947978	hsa-miR-1293	CLIP-seq
MIRT947979	hsa-miR-137	CLIP-seq
MIRT1980890	hsa-miR-224	CLIP-seq
MIRT947989	hsa-miR-3064-5p	CLIP-seq
MIRT2679587	hsa-miR-3125	CLIP-seq
MIRT2679588	hsa-miR-3133	CLIP-seq
MIRT948109	hsa-miR-3153	CLIP-seq
MIRT947994	hsa-miR-3169	CLIP-seq
MIRT948111	hsa-miR-3192	CLIP-seq
MIRT948115	hsa-miR-339-5p	CLIP-seq
MIRT948002	hsa-miR-342-5p	CLIP-seq
MIRT2679589	hsa-miR-34a	CLIP-seq
MIRT2679590	hsa-miR-34c-5p	CLIP-seq
MIRT2679591	hsa-miR-3545-3p	CLIP-seq
MIRT2520139	hsa-miR-3613-3p	CLIP-seq
MIRT2387157	hsa-miR-3620	CLIP-seq
MIRT948119	hsa-miR-3646	CLIP-seq
MIRT2679592	hsa-miR-3916	CLIP-seq
MIRT2679593	hsa-miR-3977	CLIP-seq
MIRT2679594	hsa-miR-412	CLIP-seq
MIRT2679595	hsa-miR-4256	CLIP-seq
MIRT1980900	hsa-miR-4292	CLIP-seq
MIRT1980901	hsa-miR-4308	CLIP-seq
MIRT948126	hsa-miR-4314	CLIP-seq
MIRT948018	hsa-miR-4316	CLIP-seq
MIRT948026	hsa-miR-4483	CLIP-seq
MIRT2679596	hsa-miR-449a	CLIP-seq
MIRT2679597	hsa-miR-449b	CLIP-seq
MIRT948030	hsa-miR-452	CLIP-seq
MIRT2679598	hsa-miR-4539	CLIP-seq
MIRT948132	hsa-miR-4646-5p	CLIP-seq
MIRT948037	hsa-miR-4651	CLIP-seq
MIRT948043	hsa-miR-4663	CLIP-seq
MIRT948044	hsa-miR-4664-5p	CLIP-seq
MIRT948046	hsa-miR-4676-3p	CLIP-seq
MIRT948047	hsa-miR-4676-5p	CLIP-seq
MIRT948138	hsa-miR-4699-5p	CLIP-seq
MIRT948053	hsa-miR-4728-3p	CLIP-seq
MIRT948055	hsa-miR-4731-5p	CLIP-seq
MIRT2520140	hsa-miR-4736	CLIP-seq
MIRT948060	hsa-miR-4766-3p	CLIP-seq
MIRT2679599	hsa-miR-4777-5p	CLIP-seq
MIRT948063	hsa-miR-4789-3p	CLIP-seq
MIRT2520141	hsa-miR-491-3p	CLIP-seq
MIRT2679600	hsa-miR-518d-5p	CLIP-seq
MIRT2679601	hsa-miR-519b-5p	CLIP-seq
MIRT2679602	hsa-miR-519c-5p	CLIP-seq
MIRT2679603	hsa-miR-520c-5p	CLIP-seq
MIRT2679604	hsa-miR-526a	CLIP-seq
MIRT948073	hsa-miR-539	CLIP-seq
MIRT948143	hsa-miR-541	CLIP-seq
MIRT948145	hsa-miR-548aa	CLIP-seq
MIRT948075	hsa-miR-548p	CLIP-seq
MIRT948077	hsa-miR-570	CLIP-seq
MIRT948078	hsa-miR-575	CLIP-seq
MIRT1980906	hsa-miR-604	CLIP-seq
MIRT948081	hsa-miR-608	CLIP-seq
MIRT948155	hsa-miR-622	CLIP-seq
MIRT948084	hsa-miR-642b	CLIP-seq
MIRT1980909	hsa-miR-647	CLIP-seq
MIRT948156	hsa-miR-654-5p	CLIP-seq
MIRT2215956	hsa-miR-657	CLIP-seq
MIRT1980910	hsa-miR-670	CLIP-seq
MIRT2679605	hsa-miR-877	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
CREM	Repression	21325296

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001706	Process	Endoderm formation	IBA
GO:0004721	Function	Phosphoprotein phosphatase activity	IBA
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004722	Function	Protein serine/threonine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	7535768
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	TAS
GO:0005515	Function	Protein binding	IPI	16038800, 25241761, 27880917, 31980649, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	7535768
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0007165	Process	Signal transduction	IBA
GO:0008330	Function	Protein tyrosine/threonine phosphatase activity	IDA	7535768
GO:0016311	Process	Dephosphorylation	IDA	24531476
GO:0016787	Function	Hydrolase activity	IEA
GO:0016791	Function	Phosphatase activity	IDA	24531476
GO:0017017	Function	MAP kinase tyrosine/serine/threonine phosphatase activity	IEA
GO:0033549	Function	MAP kinase phosphatase activity	IEA
GO:0043409	Process	Negative regulation of MAPK cascade	IBA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IMP	7535768
GO:1990439	Function	MAP kinase serine/threonine phosphatase activity	IDA	7535768

MIM	HGNC	e!Ensembl
602747	3070	ENSG00000120875

Protein

UniProt ID

Q13115

Protein name

Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)

Protein function

Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.

PDB

3EZZ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00581	Rhodanese	37 → 153	Rhodanese-like domain	Domain
PF00782	DSPc	203 → 333	Dual specificity phosphatase, catalytic domain	Domain

Sequence

MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC

Sequence length

394

Interactions

View interactions

	KEGG		Reactome
	MAPK signaling pathway Efferocytosis		RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Corticobasal Degeneration	Corticobasal degeneration	N/A	N/A	GWAS
Hepatocellular Carcinoma	Hepatocellular carcinoma	Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma	35864956	CBGDA
Melanoma	Melanoma	We verified that genetic inactivation of DUSP4 and PPP2R2A reduces the proliferation of melanoma cells. DUSP4 encodes an inhibitor of ERK, suggesting that further activation of MAPK signaling activity through its loss is selectively deleterious to melanom, Together, these data suggest that genetic suppression of DUSP4/6 induces growth arrest in NRAS mutant cutaneous melanoma cells through their phosphatase activity.	32767816, 34857952	CBGDA
Prostate cancer	Prostate cancer	N/A	N/A	GWAS

Show/Hide Text Mining Associations (40)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Acute Kidney Injury	Associate	30678657
Adenocarcinoma	Associate	36308185
Adenocarcinoma of Lung	Inhibit	19525976
Allergic Fungal Sinusitis	Inhibit	30657646
Atrial Fibrillation	Associate	30678657
Brain Diseases	Associate	32890776
Breast Neoplasms	Associate	23127286, 24658355, 25201346, 25629224, 26859151, 28400477, 36234680
Breast Neoplasms	Inhibit	25281216
Carcinoma Hepatocellular	Associate	20345479
Carcinoma Hepatocellular	Stimulate	29425759
Carcinoma Pancreatic Ductal	Associate	33819739
Carcinoma Renal Cell	Associate	25733583
Carcinoma Squamous Cell	Associate	22427941
Colonic Neoplasms	Associate	35774798
Colorectal Neoplasms	Associate	23350875, 26148620, 29150975, 33495832, 33662786
Delirium	Associate	30678657
Epilepsy	Inhibit	32890776
Fibrolamellar hepatocellular carcinoma	Associate	26224146
Hepatitis Alcoholic	Associate	29425759
Hereditary Breast and Ovarian Cancer Syndrome	Associate	26859151
Hypoxia	Associate	28874504
Lung Neoplasms	Associate	19525976, 28500316
Lupus Erythematosus Systemic	Stimulate	31653682
Melanoma	Associate	26084293, 31839677, 32767816, 35189148, 35580987
Myocardial Infarction	Associate	30678657
Neoplasm Metastasis	Associate	27957827, 29509059
Neoplasms	Associate	26224146, 28874504, 33760201, 34485520
Neoplasms	Inhibit	36308185
Oncogene Addiction	Associate	35580987
Opiate Overdose	Associate	35301427
Opioid Related Disorders	Associate	35301427
Ovarian Neoplasms	Associate	36362153
Pancreatic Neoplasms	Associate	39639217
Rectal Neoplasms	Associate	20725992
Stomach Neoplasms	Associate	27957827, 29509059, 33402458
Stroke	Associate	30678657
T Lymphocytopenia Idiopathic CD4 Positive	Associate	25733583
Thyroid Cancer Papillary	Associate	33760201
Triple Negative Breast Neoplasms	Associate	25201346, 25281216, 27604655
Uveal melanoma	Associate	36576731

DUSP4 (dual specificity phosphatase 4)