ECM2 (extracellular matrix protein 2)

Gene
Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1842
Gene name Gene Name - the full gene name approved by the HGNC.
Extracellular matrix protein 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ECM2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q22.31
Summary Summary of gene provided in NCBI Entrez Gene.
ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(15)
miRTarBase ID miRNA Experiments Reference
MIRT027441 hsa-miR-98-5p Microarray 19088304
MIRT037131 hsa-miR-877-3p CLASH 23622248
MIRT951792 hsa-miR-3144-3p CLIP-seq
MIRT951793 hsa-miR-3606 CLIP-seq
MIRT951794 hsa-miR-3915 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(7)
GO ID Ontology Definition Evidence Reference
GO:0005178 Function Integrin binding TAS 9790758
GO:0007160 Process Cell-matrix adhesion TAS 9790758
GO:0008201 Function Heparin binding IBA 21873635
GO:0010811 Process Positive regulation of cell-substrate adhesion IBA 21873635
GO:0030198 Process Extracellular matrix organization IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
603479 3154 ENSG00000106823
Protein
Gene miRNA Gene ontology Other IDs Protein
UniProt ID O94769
Protein name Extracellular matrix protein 2 (Matrix glycoprotein SC1/ECM2)
Protein function Promotes matrix assembly and cell adhesiveness.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00093 VWC 103 → 157 von Willebrand factor type C domain Family
PF13855 LRR_8 485 → 547 Leucine rich repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Expressed predominantly in adipose tissue as well as female-specific organs such as mammary gland, ovary, and uterus. {ECO:0000269|PubMed:9790758}.
Sequence 
MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
DLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDR
VSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDS
NLEHLHLENNYIKIREIPSYTFSCIRSYSSIVLKPQNIK
Sequence length 699
Interactions View interactions