Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1810
Gene name Gene Name - the full gene name approved by the HGNC.	Down-regulator of transcription 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DR1
Synonyms (NCBI Gene) Gene synonyms aliases	NC2, NC2-BETA, NC2B, NCB2
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This pr

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020005	hsa-miR-375	Microarray	20215506
MIRT020974	hsa-miR-155-5p	Proteomics	20584899
MIRT044688	hsa-miR-320a	CLASH	23622248
MIRT054518	hsa-miR-513a-5p	Luciferase reporter assay, qRT-PCR, Western blot	24252134
MIRT054519	hsa-miR-513b-5p	Luciferase reporter assay, qRT-PCR, Western blot	24252134
MIRT054520	hsa-miR-513c-5p	Luciferase reporter assay, qRT-PCR, Western blot	24252134
MIRT668680	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT668679	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT668678	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT668677	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT668676	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT668675	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT668674	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT668673	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT668672	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT668671	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT668670	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT668669	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT293263	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT624085	hsa-miR-8080	HITS-CLIP	23824327
MIRT624084	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT624083	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT624082	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT624085	hsa-miR-8080	HITS-CLIP	23824327
MIRT624084	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT624083	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT624082	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT624081	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT624080	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT624079	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT483466	hsa-miR-4759	PAR-CLIP	20371350
MIRT483467	hsa-miR-3169	PAR-CLIP	20371350
MIRT483465	hsa-miR-8083	PAR-CLIP	20371350
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	20371350
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	20371350
MIRT483466	hsa-miR-4759	PAR-CLIP	20371350
MIRT483467	hsa-miR-3169	PAR-CLIP	20371350
MIRT483465	hsa-miR-8083	PAR-CLIP	20371350
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	20371350
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	20371350
MIRT293284	hsa-miR-137	PAR-CLIP	21572407
MIRT293290	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT293285	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT293286	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT388009	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT388010	hsa-miR-499b-3p	PAR-CLIP	21572407
MIRT558321	hsa-miR-4457	PAR-CLIP	21572407
MIRT558320	hsa-miR-125b-2-3p	PAR-CLIP	21572407
MIRT293289	hsa-miR-4635	PAR-CLIP	21572407
MIRT293287	hsa-miR-3185	PAR-CLIP	21572407
MIRT558319	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT293248	hsa-miR-548n	PAR-CLIP	21572407
MIRT548550	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT548549	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT293244	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT293256	hsa-miR-548ab	PAR-CLIP	21572407
MIRT293258	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT293259	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT293260	hsa-miR-548ak	PAR-CLIP	21572407
MIRT293262	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT293264	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT293265	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT293266	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT293267	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT293268	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT293270	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT293243	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT293271	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT293245	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT293246	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT293249	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT293250	hsa-miR-548i	PAR-CLIP	21572407
MIRT293247	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT293255	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT293252	hsa-miR-548w	PAR-CLIP	21572407
MIRT293254	hsa-miR-548y	PAR-CLIP	21572407
MIRT293242	hsa-miR-559	PAR-CLIP	21572407
MIRT548548	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT548547	hsa-miR-4715-5p	PAR-CLIP	21572407
MIRT293253	hsa-miR-4259	PAR-CLIP	21572407
MIRT293261	hsa-miR-4495	PAR-CLIP	21572407
MIRT548546	hsa-miR-4529-5p	PAR-CLIP	21572407
MIRT548544	hsa-miR-3153	PAR-CLIP	21572407
MIRT548545	hsa-miR-6733-5p	PAR-CLIP	21572407
MIRT548543	hsa-miR-6739-5p	PAR-CLIP	21572407
MIRT293257	hsa-miR-4425	PAR-CLIP	21572407
MIRT548542	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT293241	hsa-miR-450a-1-3p	PAR-CLIP	21572407
MIRT483466	hsa-miR-4759	PAR-CLIP	21572407
MIRT483467	hsa-miR-3169	PAR-CLIP	21572407
MIRT483465	hsa-miR-8083	PAR-CLIP	21572407
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	21572407
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	21572407
MIRT494093	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT483466	hsa-miR-4759	PAR-CLIP	23592263
MIRT483467	hsa-miR-3169	PAR-CLIP	23592263
MIRT483465	hsa-miR-8083	PAR-CLIP	23592263
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	23592263
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	23592263
MIRT494093	hsa-miR-340-5p	PAR-CLIP	23592263
MIRT483466	hsa-miR-4759	PAR-CLIP	23592263
MIRT483467	hsa-miR-3169	PAR-CLIP	23592263
MIRT483465	hsa-miR-8083	PAR-CLIP	23592263
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	23592263
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	23592263
MIRT448879	hsa-miR-384	PAR-CLIP	22100165
MIRT448878	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448877	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448876	hsa-miR-5571-3p	PAR-CLIP	22100165
MIRT448875	hsa-miR-7975	PAR-CLIP	22100165
MIRT448873	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448874	hsa-miR-573	PAR-CLIP	22100165
MIRT448879	hsa-miR-384	PAR-CLIP	22100165
MIRT448878	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448877	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448876	hsa-miR-5571-3p	PAR-CLIP	22100165
MIRT448875	hsa-miR-7975	PAR-CLIP	22100165
MIRT448873	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448874	hsa-miR-573	PAR-CLIP	22100165
MIRT668680	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT668679	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT668678	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT668677	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT668676	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT668675	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT668674	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT668673	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT668672	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT668671	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT668670	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT668669	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT293263	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT624085	hsa-miR-8080	HITS-CLIP	23824327
MIRT624084	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT624083	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT624082	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT624085	hsa-miR-8080	HITS-CLIP	23824327
MIRT624084	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT624083	hsa-miR-3121-5p	HITS-CLIP	23824327
MIRT624082	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT624081	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT624080	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT624079	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT483466	hsa-miR-4759	PAR-CLIP	20371350
MIRT483467	hsa-miR-3169	PAR-CLIP	20371350
MIRT483465	hsa-miR-8083	PAR-CLIP	20371350
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	20371350
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	20371350
MIRT483466	hsa-miR-4759	PAR-CLIP	20371350
MIRT483467	hsa-miR-3169	PAR-CLIP	20371350
MIRT483465	hsa-miR-8083	PAR-CLIP	20371350
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	20371350
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	20371350
MIRT293284	hsa-miR-137	PAR-CLIP	21572407
MIRT293290	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT293285	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT293286	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT388009	hsa-miR-499a-3p	PAR-CLIP	21572407
MIRT388010	hsa-miR-499b-3p	PAR-CLIP	21572407
MIRT558321	hsa-miR-4457	PAR-CLIP	21572407
MIRT558320	hsa-miR-125b-2-3p	PAR-CLIP	21572407
MIRT293289	hsa-miR-4635	PAR-CLIP	21572407
MIRT293287	hsa-miR-3185	PAR-CLIP	21572407
MIRT558319	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT293248	hsa-miR-548n	PAR-CLIP	21572407
MIRT548550	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT548549	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT293244	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT293256	hsa-miR-548ab	PAR-CLIP	21572407
MIRT293258	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT293259	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT293260	hsa-miR-548ak	PAR-CLIP	21572407
MIRT293262	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT293264	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT293265	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT293266	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT293267	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT293268	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT293270	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT293243	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT293271	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT293245	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT293246	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT293249	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT293250	hsa-miR-548i	PAR-CLIP	21572407
MIRT293247	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT293255	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT293252	hsa-miR-548w	PAR-CLIP	21572407
MIRT293254	hsa-miR-548y	PAR-CLIP	21572407
MIRT293242	hsa-miR-559	PAR-CLIP	21572407
MIRT548548	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT548547	hsa-miR-4715-5p	PAR-CLIP	21572407
MIRT293253	hsa-miR-4259	PAR-CLIP	21572407
MIRT293261	hsa-miR-4495	PAR-CLIP	21572407
MIRT548546	hsa-miR-4529-5p	PAR-CLIP	21572407
MIRT548544	hsa-miR-3153	PAR-CLIP	21572407
MIRT548545	hsa-miR-6733-5p	PAR-CLIP	21572407
MIRT548543	hsa-miR-6739-5p	PAR-CLIP	21572407
MIRT293257	hsa-miR-4425	PAR-CLIP	21572407
MIRT548542	hsa-miR-4799-5p	PAR-CLIP	21572407
MIRT293241	hsa-miR-450a-1-3p	PAR-CLIP	21572407
MIRT483466	hsa-miR-4759	PAR-CLIP	21572407
MIRT483467	hsa-miR-3169	PAR-CLIP	21572407
MIRT483465	hsa-miR-8083	PAR-CLIP	21572407
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	21572407
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	21572407
MIRT494093	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT483466	hsa-miR-4759	PAR-CLIP	23592263
MIRT483467	hsa-miR-3169	PAR-CLIP	23592263
MIRT483465	hsa-miR-8083	PAR-CLIP	23592263
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	23592263
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	23592263
MIRT494093	hsa-miR-340-5p	PAR-CLIP	23592263
MIRT483466	hsa-miR-4759	PAR-CLIP	23592263
MIRT483467	hsa-miR-3169	PAR-CLIP	23592263
MIRT483465	hsa-miR-8083	PAR-CLIP	23592263
MIRT483464	hsa-miR-3607-3p	PAR-CLIP	23592263
MIRT483463	hsa-miR-3117-3p	PAR-CLIP	23592263
MIRT448879	hsa-miR-384	PAR-CLIP	22100165
MIRT448878	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448877	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448876	hsa-miR-5571-3p	PAR-CLIP	22100165
MIRT448875	hsa-miR-7975	PAR-CLIP	22100165
MIRT448873	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448874	hsa-miR-573	PAR-CLIP	22100165
MIRT448879	hsa-miR-384	PAR-CLIP	22100165
MIRT448878	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT448877	hsa-miR-431-5p	PAR-CLIP	22100165
MIRT448876	hsa-miR-5571-3p	PAR-CLIP	22100165
MIRT448875	hsa-miR-7975	PAR-CLIP	22100165
MIRT448873	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT448874	hsa-miR-573	PAR-CLIP	22100165
MIRT945147	hsa-miR-1208	CLIP-seq
MIRT945148	hsa-miR-122	CLIP-seq
MIRT945149	hsa-miR-1245b-3p	CLIP-seq
MIRT945150	hsa-miR-1285	CLIP-seq
MIRT945151	hsa-miR-141	CLIP-seq
MIRT945152	hsa-miR-194	CLIP-seq
MIRT945153	hsa-miR-200a	CLIP-seq
MIRT945154	hsa-miR-203	CLIP-seq
MIRT945155	hsa-miR-219-2-3p	CLIP-seq
MIRT945156	hsa-miR-224	CLIP-seq
MIRT945157	hsa-miR-2964a-3p	CLIP-seq
MIRT945158	hsa-miR-3065-3p	CLIP-seq
MIRT945159	hsa-miR-3161	CLIP-seq
MIRT945160	hsa-miR-3164	CLIP-seq
MIRT945161	hsa-miR-3187-5p	CLIP-seq
MIRT945162	hsa-miR-3198	CLIP-seq
MIRT945163	hsa-miR-323-3p	CLIP-seq
MIRT945164	hsa-miR-340	CLIP-seq
MIRT945165	hsa-miR-361-5p	CLIP-seq
MIRT945166	hsa-miR-3646	CLIP-seq
MIRT945167	hsa-miR-3647-5p	CLIP-seq
MIRT945168	hsa-miR-3662	CLIP-seq
MIRT945169	hsa-miR-3670	CLIP-seq
MIRT945170	hsa-miR-3681	CLIP-seq
MIRT945171	hsa-miR-3686	CLIP-seq
MIRT945172	hsa-miR-369-3p	CLIP-seq
MIRT945173	hsa-miR-371b-5p	CLIP-seq
MIRT945174	hsa-miR-374a	CLIP-seq
MIRT945175	hsa-miR-374b	CLIP-seq
MIRT945176	hsa-miR-374c	CLIP-seq
MIRT945177	hsa-miR-377	CLIP-seq
MIRT945178	hsa-miR-4309	CLIP-seq
MIRT945179	hsa-miR-4420	CLIP-seq
MIRT945180	hsa-miR-452	CLIP-seq
MIRT945181	hsa-miR-4539	CLIP-seq
MIRT945182	hsa-miR-4633-3p	CLIP-seq
MIRT945183	hsa-miR-4652-3p	CLIP-seq
MIRT945184	hsa-miR-4676-3p	CLIP-seq
MIRT945185	hsa-miR-4680-3p	CLIP-seq
MIRT945186	hsa-miR-4680-5p	CLIP-seq
MIRT945187	hsa-miR-4698	CLIP-seq
MIRT945188	hsa-miR-4711-5p	CLIP-seq
MIRT945189	hsa-miR-4728-3p	CLIP-seq
MIRT945190	hsa-miR-4742-3p	CLIP-seq
MIRT945191	hsa-miR-490-3p	CLIP-seq
MIRT945192	hsa-miR-499a-5p	CLIP-seq
MIRT945193	hsa-miR-513a-3p	CLIP-seq
MIRT945194	hsa-miR-548c-3p	CLIP-seq
MIRT945195	hsa-miR-612	CLIP-seq
MIRT945196	hsa-miR-617	CLIP-seq
MIRT945197	hsa-miR-645	CLIP-seq
MIRT945198	hsa-miR-649	CLIP-seq
MIRT945199	hsa-miR-655	CLIP-seq
MIRT1979797	hsa-miR-105	CLIP-seq
MIRT945147	hsa-miR-1208	CLIP-seq
MIRT1979798	hsa-miR-1269	CLIP-seq
MIRT1979799	hsa-miR-1269b	CLIP-seq
MIRT1979800	hsa-miR-1323	CLIP-seq
MIRT945151	hsa-miR-141	CLIP-seq
MIRT945152	hsa-miR-194	CLIP-seq
MIRT945153	hsa-miR-200a	CLIP-seq
MIRT1979801	hsa-miR-300	CLIP-seq
MIRT945158	hsa-miR-3065-3p	CLIP-seq
MIRT1979802	hsa-miR-3129-3p	CLIP-seq
MIRT1979803	hsa-miR-3158-3p	CLIP-seq
MIRT1979804	hsa-miR-337-3p	CLIP-seq
MIRT945166	hsa-miR-3646	CLIP-seq
MIRT945168	hsa-miR-3662	CLIP-seq
MIRT945169	hsa-miR-3670	CLIP-seq
MIRT1979805	hsa-miR-3690	CLIP-seq
MIRT1979806	hsa-miR-371-5p	CLIP-seq
MIRT945173	hsa-miR-371b-5p	CLIP-seq
MIRT945177	hsa-miR-377	CLIP-seq
MIRT1979807	hsa-miR-381	CLIP-seq
MIRT1979808	hsa-miR-383	CLIP-seq
MIRT1979809	hsa-miR-3913-3p	CLIP-seq
MIRT1979810	hsa-miR-409-3p	CLIP-seq
MIRT1979811	hsa-miR-421	CLIP-seq
MIRT1979812	hsa-miR-4254	CLIP-seq
MIRT1979813	hsa-miR-4320	CLIP-seq
MIRT1979814	hsa-miR-4446-3p	CLIP-seq
MIRT1979815	hsa-miR-4503	CLIP-seq
MIRT1979816	hsa-miR-4517	CLIP-seq
MIRT945180	hsa-miR-452	CLIP-seq
MIRT1979817	hsa-miR-4529-3p	CLIP-seq
MIRT1979818	hsa-miR-4656	CLIP-seq
MIRT1979819	hsa-miR-4666-3p	CLIP-seq
MIRT945184	hsa-miR-4676-3p	CLIP-seq
MIRT945186	hsa-miR-4680-5p	CLIP-seq
MIRT945187	hsa-miR-4698	CLIP-seq
MIRT1979820	hsa-miR-4717-5p	CLIP-seq
MIRT1979821	hsa-miR-4772-5p	CLIP-seq
MIRT1979822	hsa-miR-4781-3p	CLIP-seq
MIRT1979823	hsa-miR-4793-5p	CLIP-seq
MIRT1979824	hsa-miR-4803	CLIP-seq
MIRT1979825	hsa-miR-489	CLIP-seq
MIRT1979826	hsa-miR-496	CLIP-seq
MIRT945193	hsa-miR-513a-3p	CLIP-seq
MIRT1979827	hsa-miR-548a-3p	CLIP-seq
MIRT1979828	hsa-miR-548ag	CLIP-seq
MIRT1979829	hsa-miR-548ai	CLIP-seq
MIRT1979830	hsa-miR-548e	CLIP-seq
MIRT1979831	hsa-miR-548f	CLIP-seq
MIRT1979832	hsa-miR-548m	CLIP-seq
MIRT1979833	hsa-miR-548o	CLIP-seq
MIRT1979834	hsa-miR-548p	CLIP-seq
MIRT1979835	hsa-miR-579	CLIP-seq
MIRT945197	hsa-miR-645	CLIP-seq
MIRT1979797	hsa-miR-105	CLIP-seq
MIRT2215006	hsa-miR-1193	CLIP-seq
MIRT945147	hsa-miR-1208	CLIP-seq
MIRT945149	hsa-miR-1245b-3p	CLIP-seq
MIRT2215007	hsa-miR-1246	CLIP-seq
MIRT945150	hsa-miR-1285	CLIP-seq
MIRT945151	hsa-miR-141	CLIP-seq
MIRT945153	hsa-miR-200a	CLIP-seq
MIRT945154	hsa-miR-203	CLIP-seq
MIRT2215008	hsa-miR-2054	CLIP-seq
MIRT945156	hsa-miR-224	CLIP-seq
MIRT2215009	hsa-miR-3166	CLIP-seq
MIRT945161	hsa-miR-3187-5p	CLIP-seq
MIRT2215010	hsa-miR-320b	CLIP-seq
MIRT2215011	hsa-miR-320c	CLIP-seq
MIRT2215012	hsa-miR-320d	CLIP-seq
MIRT945163	hsa-miR-323-3p	CLIP-seq
MIRT1979804	hsa-miR-337-3p	CLIP-seq
MIRT945164	hsa-miR-340	CLIP-seq
MIRT2215013	hsa-miR-34c-3p	CLIP-seq
MIRT945165	hsa-miR-361-5p	CLIP-seq
MIRT945166	hsa-miR-3646	CLIP-seq
MIRT945167	hsa-miR-3647-5p	CLIP-seq
MIRT945168	hsa-miR-3662	CLIP-seq
MIRT2215014	hsa-miR-3667-3p	CLIP-seq
MIRT945169	hsa-miR-3670	CLIP-seq
MIRT945170	hsa-miR-3681	CLIP-seq
MIRT1979805	hsa-miR-3690	CLIP-seq
MIRT945172	hsa-miR-369-3p	CLIP-seq
MIRT945173	hsa-miR-371b-5p	CLIP-seq
MIRT945174	hsa-miR-374a	CLIP-seq
MIRT945175	hsa-miR-374b	CLIP-seq
MIRT945176	hsa-miR-374c	CLIP-seq
MIRT1979809	hsa-miR-3913-3p	CLIP-seq
MIRT2215015	hsa-miR-3925-5p	CLIP-seq
MIRT1979811	hsa-miR-421	CLIP-seq
MIRT2215016	hsa-miR-425	CLIP-seq
MIRT1979812	hsa-miR-4254	CLIP-seq
MIRT2215017	hsa-miR-4282	CLIP-seq
MIRT2215018	hsa-miR-431	CLIP-seq
MIRT1979813	hsa-miR-4320	CLIP-seq
MIRT2215019	hsa-miR-4325	CLIP-seq
MIRT2215020	hsa-miR-4328	CLIP-seq
MIRT2215021	hsa-miR-4429	CLIP-seq
MIRT945180	hsa-miR-452	CLIP-seq
MIRT945181	hsa-miR-4539	CLIP-seq
MIRT945182	hsa-miR-4633-3p	CLIP-seq
MIRT2215022	hsa-miR-4666-5p	CLIP-seq
MIRT945184	hsa-miR-4676-3p	CLIP-seq
MIRT945186	hsa-miR-4680-5p	CLIP-seq
MIRT945187	hsa-miR-4698	CLIP-seq
MIRT2215023	hsa-miR-4718	CLIP-seq
MIRT945189	hsa-miR-4728-3p	CLIP-seq
MIRT1979823	hsa-miR-4793-5p	CLIP-seq
MIRT1979825	hsa-miR-489	CLIP-seq
MIRT945192	hsa-miR-499a-5p	CLIP-seq
MIRT2215024	hsa-miR-5096	CLIP-seq
MIRT945193	hsa-miR-513a-3p	CLIP-seq
MIRT1979827	hsa-miR-548a-3p	CLIP-seq
MIRT945194	hsa-miR-548c-3p	CLIP-seq
MIRT1979830	hsa-miR-548e	CLIP-seq
MIRT1979831	hsa-miR-548f	CLIP-seq
MIRT1979835	hsa-miR-579	CLIP-seq
MIRT2215025	hsa-miR-589	CLIP-seq
MIRT945195	hsa-miR-612	CLIP-seq
MIRT945196	hsa-miR-617	CLIP-seq
MIRT2215026	hsa-miR-633	CLIP-seq
MIRT2215027	hsa-miR-639	CLIP-seq
MIRT945197	hsa-miR-645	CLIP-seq
MIRT945199	hsa-miR-655	CLIP-seq
MIRT2215028	hsa-miR-720	CLIP-seq
MIRT945158	hsa-miR-3065-3p	CLIP-seq
MIRT945177	hsa-miR-377	CLIP-seq
MIRT945147	hsa-miR-1208	CLIP-seq
MIRT2519472	hsa-miR-1909	CLIP-seq
MIRT2519473	hsa-miR-200b	CLIP-seq
MIRT2519474	hsa-miR-200c	CLIP-seq
MIRT2519475	hsa-miR-3148	CLIP-seq
MIRT945160	hsa-miR-3164	CLIP-seq
MIRT945176	hsa-miR-374c	CLIP-seq
MIRT2519476	hsa-miR-3944-5p	CLIP-seq
MIRT2519477	hsa-miR-429	CLIP-seq
MIRT945179	hsa-miR-4420	CLIP-seq
MIRT945180	hsa-miR-452	CLIP-seq
MIRT2519478	hsa-miR-4633-5p	CLIP-seq
MIRT945183	hsa-miR-4652-3p	CLIP-seq
MIRT945184	hsa-miR-4676-3p	CLIP-seq
MIRT945199	hsa-miR-655	CLIP-seq
MIRT945147	hsa-miR-1208	CLIP-seq
MIRT2519473	hsa-miR-200b	CLIP-seq
MIRT2519474	hsa-miR-200c	CLIP-seq
MIRT945176	hsa-miR-374c	CLIP-seq
MIRT2519477	hsa-miR-429	CLIP-seq
MIRT945179	hsa-miR-4420	CLIP-seq
MIRT945180	hsa-miR-452	CLIP-seq
MIRT945183	hsa-miR-4652-3p	CLIP-seq
MIRT945184	hsa-miR-4676-3p	CLIP-seq
MIRT945199	hsa-miR-655	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
BTAF1	Repression	20627952
NR2F1	Repression	22357705

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA	21873635
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	8670811
GO:0001046	Function	Core promoter sequence-specific DNA binding	IBA	21873635
GO:0003713	Function	Transcription coactivator activity	IBA	21873635
GO:0003714	Function	Transcription corepressor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	8670811, 16189514, 18692475, 18838386, 29997244, 31467278, 31515488, 32296183, 32814053
GO:0005654	Component	Nucleoplasm	IDA
GO:0005671	Component	Ada2/Gcn5/Ada3 transcription activator complex	IBA	21873635
GO:0005671	Component	Ada2/Gcn5/Ada3 transcription activator complex	IDA	18838386
GO:0006338	Process	Chromatin remodeling	IBA	21873635
GO:0016251	Function	RNA polymerase II general transcription initiation factor activity	IDA	8670811
GO:0017025	Function	TBP-class protein binding	IBA	21873635
GO:0017025	Function	TBP-class protein binding	IDA	18838386
GO:0017025	Function	TBP-class protein binding	IPI	8670811
GO:0017054	Component	Negative cofactor 2 complex	IBA	21873635
GO:0043966	Process	Histone H3 acetylation	IDA	18838386
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0051123	Process	RNA polymerase II preinitiation complex assembly	IBA	21873635
GO:0090575	Component	RNA polymerase II transcription regulator complex	IDA	8670811

MIM	HGNC	e!Ensembl
601482	3017	ENSG00000117505

Protein

UniProt ID

Q01658

Protein name

Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)

Protein function

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the

PDB

1JFI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00808	CBFD_NFYB_HMF	11 → 75	Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Domain

Sequence

MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK
SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR
QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI

Sequence length

176

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Source
Unknown
Metabolic Syndrome	Metabolic Syndrome	GWAS
Inflammatory Bowel Disease	Inflammatory Bowel Disease	GWAS
Crohn Disease	Crohn Disease	GWAS

Show/Hide Text Mining Associations (34)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenoma	Associate	19293270
Adrenal Hyperplasia Congenital	Associate	2226916
Arthritis Rheumatoid	Associate	11407687, 1466602, 1496989, 17346433, 17491100, 19014626, 1974413, 2042983, 2481309, 2732676, 6428222, 6606398, 7688934, 8154934, 8496681, 8571964 View all (1 more)
Arthritis Rheumatoid	Stimulate	1371662
Carcinoma Non Small Cell Lung	Associate	20473949
Carcinoma Squamous Cell	Stimulate	25135188
Colorectal Neoplasms	Associate	26222778
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency	Associate	15004406, 18187875, 2443540, 3013005, 6789674
Crohn Disease	Associate	10689124, 8349790
Diabetes Mellitus	Associate	20966625, 8700877
Diabetes Mellitus Type 1	Associate	20966625, 24034553, 2979618, 6334991, 8900244
Epidermolysis Bullosa Acquisita	Associate	11274208
Epidermolysis Bullosa Dystrophica	Associate	11274208, 7593178
Graft vs Host Disease	Associate	11472342
Granulomatosis with Polyangiitis	Associate	1550412
Hepatitis Autoimmune	Associate	21301006
Hypoxia	Stimulate	12477712
Hypoxia Brain	Associate	12477712
IgA Deficiency	Associate	19052350
Inflammatory Bowel Diseases	Associate	10689124
Influenza Human	Associate	8154934
Late Onset Disorders	Associate	2226916
Leukemia Lymphocytic Chronic B Cell	Associate	10393367
Meibomian Gland Dysfunction	Associate	18618006
Melanoma	Associate	36512357
Multiple Sclerosis Relapsing Remitting	Associate	15834022
Neoplasms	Associate	19707583
Neuroblastoma	Associate	18538002
Osteosarcoma	Associate	1447210
Pemphigus and fogo selvagem	Associate	10417627
Pituitary Neoplasms	Associate	19293270
Sleep Disorders Circadian Rhythm	Stimulate	11186112
Trifunctional Protein Deficiency With Myopathy And Neuropathy	Associate	15004406, 3013005
Urinary Bladder Neoplasms	Associate	25135188

DR1 (down-regulator of transcription 1)