|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1808
|
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Dihydropyrimidinase like 2 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
DPYSL2 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 |
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Chromosome
Chromosome number
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8 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p21.2 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and i |
| UniProt ID |
Q16555
|
| Protein name |
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2) |
| Protein function |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a |
| PDB |
2GSE
,
2VM8
,
5LXX
,
5MKV
,
5MLE
,
5X1A
,
5X1C
,
5X1D
,
5YZ5
,
5YZA
,
5YZB
,
6JV9
,
6JVB
,
7X68
,
8DNM
|
| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
|
PF01979
|
Amidohydro_1 |
64 → 453 |
Amidohydrolase family |
Domain |
|
| Tissue specificity |
TISSUE SPECIFICITY: Ubiquitous. |
| Sequence |
|
| Sequence length |
572 |
| Interactions |
View interactions
|