Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1728
Gene name	NAD(P)H quinone dehydrogenase 1
Gene symbol	NQO1
Synonyms (NCBI Gene)	DHQUDIA4DTDNMOR1NMORIQR1
Chromosome	16
Chromosome location	16q22.1
Summary	This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein`s enzymatic activity prevents the one electro

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1800566	G>A	Drug-response, risk-factor, not-provided, pathogenic	Missense variant, coding sequence variant
rs1555537451	G>A	Likely-pathogenic	Stop gained, coding sequence variant

498

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miRTarBase ID	miRNA	Experiments
MIRT1191823	hsa-let-7a	CLIP-seq
MIRT1191824	hsa-let-7b	CLIP-seq
MIRT1191825	hsa-let-7c	CLIP-seq
MIRT1191826	hsa-let-7d	CLIP-seq
MIRT1191827	hsa-let-7e	CLIP-seq
MIRT1191828	hsa-let-7f	CLIP-seq
MIRT1191829	hsa-let-7g	CLIP-seq
MIRT1191830	hsa-let-7i	CLIP-seq
MIRT1191831	hsa-miR-1207-5p	CLIP-seq
MIRT1191832	hsa-miR-1252	CLIP-seq
MIRT1191833	hsa-miR-1254	CLIP-seq
MIRT1191834	hsa-miR-1270	CLIP-seq
MIRT1191835	hsa-miR-1273f	CLIP-seq
MIRT1191836	hsa-miR-1305	CLIP-seq
MIRT1191837	hsa-miR-143	CLIP-seq
MIRT1191838	hsa-miR-185	CLIP-seq
MIRT1191839	hsa-miR-188-5p	CLIP-seq
MIRT1191840	hsa-miR-1912	CLIP-seq
MIRT1191841	hsa-miR-202	CLIP-seq
MIRT1191842	hsa-miR-205	CLIP-seq
MIRT1191843	hsa-miR-219-1-3p	CLIP-seq
MIRT1191844	hsa-miR-3065-5p	CLIP-seq
MIRT1191845	hsa-miR-3116	CLIP-seq
MIRT1191846	hsa-miR-3122	CLIP-seq
MIRT1191847	hsa-miR-3130-5p	CLIP-seq
MIRT1191848	hsa-miR-3148	CLIP-seq
MIRT1191849	hsa-miR-3154	CLIP-seq
MIRT1191850	hsa-miR-3161	CLIP-seq
MIRT1191851	hsa-miR-3165	CLIP-seq
MIRT1191852	hsa-miR-3173-3p	CLIP-seq
MIRT1191853	hsa-miR-3180-5p	CLIP-seq
MIRT1191854	hsa-miR-3190	CLIP-seq
MIRT1191855	hsa-miR-3622a-3p	CLIP-seq
MIRT1191856	hsa-miR-3622b-3p	CLIP-seq
MIRT1191857	hsa-miR-3672	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT1191860	hsa-miR-3913-5p	CLIP-seq
MIRT1191861	hsa-miR-3929	CLIP-seq
MIRT1191862	hsa-miR-3978	CLIP-seq
MIRT1191863	hsa-miR-423-3p	CLIP-seq
MIRT1191864	hsa-miR-4267	CLIP-seq
MIRT1191865	hsa-miR-4269	CLIP-seq
MIRT1191866	hsa-miR-4306	CLIP-seq
MIRT1191867	hsa-miR-4310	CLIP-seq
MIRT1191868	hsa-miR-4419b	CLIP-seq
MIRT1191869	hsa-miR-4433	CLIP-seq
MIRT1191870	hsa-miR-4458	CLIP-seq
MIRT1191871	hsa-miR-4459	CLIP-seq
MIRT1191872	hsa-miR-4478	CLIP-seq
MIRT1191873	hsa-miR-4482	CLIP-seq
MIRT1191874	hsa-miR-4490	CLIP-seq
MIRT1191875	hsa-miR-4493	CLIP-seq
MIRT1191876	hsa-miR-4500	CLIP-seq
MIRT1191877	hsa-miR-4514	CLIP-seq
MIRT1191878	hsa-miR-4521	CLIP-seq
MIRT1191879	hsa-miR-4531	CLIP-seq
MIRT1191880	hsa-miR-4644	CLIP-seq
MIRT1191881	hsa-miR-4645-5p	CLIP-seq
MIRT1191882	hsa-miR-4662a-5p	CLIP-seq
MIRT1191883	hsa-miR-4673	CLIP-seq
MIRT1191884	hsa-miR-4684-5p	CLIP-seq
MIRT1191885	hsa-miR-4692	CLIP-seq
MIRT1191886	hsa-miR-4699-5p	CLIP-seq
MIRT1191887	hsa-miR-4708-5p	CLIP-seq
MIRT1191888	hsa-miR-4719	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191890	hsa-miR-4729	CLIP-seq
MIRT1191891	hsa-miR-4736	CLIP-seq
MIRT1191892	hsa-miR-4742-5p	CLIP-seq
MIRT1191893	hsa-miR-4746-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT1191895	hsa-miR-4762-5p	CLIP-seq
MIRT1191896	hsa-miR-4763-3p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191898	hsa-miR-4770	CLIP-seq
MIRT1191899	hsa-miR-4774-5p	CLIP-seq
MIRT1191900	hsa-miR-485-5p	CLIP-seq
MIRT1191901	hsa-miR-502-5p	CLIP-seq
MIRT1191902	hsa-miR-520a-5p	CLIP-seq
MIRT1191903	hsa-miR-525-5p	CLIP-seq
MIRT1191904	hsa-miR-544b	CLIP-seq
MIRT1191905	hsa-miR-548c-3p	CLIP-seq
MIRT1191906	hsa-miR-548g	CLIP-seq
MIRT1191907	hsa-miR-617	CLIP-seq
MIRT1191908	hsa-miR-620	CLIP-seq
MIRT1191909	hsa-miR-875-3p	CLIP-seq
MIRT1191910	hsa-miR-98	CLIP-seq
MIRT1191823	hsa-let-7a	CLIP-seq
MIRT1191824	hsa-let-7b	CLIP-seq
MIRT1191825	hsa-let-7c	CLIP-seq
MIRT1191826	hsa-let-7d	CLIP-seq
MIRT1191827	hsa-let-7e	CLIP-seq
MIRT1191828	hsa-let-7f	CLIP-seq
MIRT1191829	hsa-let-7g	CLIP-seq
MIRT1191830	hsa-let-7i	CLIP-seq
MIRT1191911	hsa-miR-1225-3p	CLIP-seq
MIRT1191912	hsa-miR-1228	CLIP-seq
MIRT1191913	hsa-miR-1233	CLIP-seq
MIRT1191914	hsa-miR-1237	CLIP-seq
MIRT1191915	hsa-miR-1248	CLIP-seq
MIRT1191833	hsa-miR-1254	CLIP-seq
MIRT1191916	hsa-miR-1287	CLIP-seq
MIRT1191917	hsa-miR-1290	CLIP-seq
MIRT1191918	hsa-miR-1296	CLIP-seq
MIRT1191919	hsa-miR-1827	CLIP-seq
MIRT1191840	hsa-miR-1912	CLIP-seq
MIRT1191920	hsa-miR-194	CLIP-seq
MIRT1191841	hsa-miR-202	CLIP-seq
MIRT1191921	hsa-miR-204	CLIP-seq
MIRT1191922	hsa-miR-2054	CLIP-seq
MIRT1191923	hsa-miR-211	CLIP-seq
MIRT1191924	hsa-miR-2114	CLIP-seq
MIRT1191925	hsa-miR-218	CLIP-seq
MIRT1191926	hsa-miR-2467-3p	CLIP-seq
MIRT1191927	hsa-miR-2909	CLIP-seq
MIRT1191928	hsa-miR-2964a-3p	CLIP-seq
MIRT1191929	hsa-miR-302f	CLIP-seq
MIRT1191845	hsa-miR-3116	CLIP-seq
MIRT1191846	hsa-miR-3122	CLIP-seq
MIRT1191847	hsa-miR-3130-5p	CLIP-seq
MIRT1191930	hsa-miR-3135b	CLIP-seq
MIRT1191850	hsa-miR-3161	CLIP-seq
MIRT1191931	hsa-miR-3192	CLIP-seq
MIRT1191932	hsa-miR-3612	CLIP-seq
MIRT1191855	hsa-miR-3622a-3p	CLIP-seq
MIRT1191856	hsa-miR-3622b-3p	CLIP-seq
MIRT1191857	hsa-miR-3672	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT1191860	hsa-miR-3913-5p	CLIP-seq
MIRT1191933	hsa-miR-3921	CLIP-seq
MIRT1191934	hsa-miR-3927	CLIP-seq
MIRT1191861	hsa-miR-3929	CLIP-seq
MIRT1191935	hsa-miR-3938	CLIP-seq
MIRT1191862	hsa-miR-3978	CLIP-seq
MIRT1191936	hsa-miR-4257	CLIP-seq
MIRT1191937	hsa-miR-4270	CLIP-seq
MIRT1191938	hsa-miR-4303	CLIP-seq
MIRT1191868	hsa-miR-4419b	CLIP-seq
MIRT1191939	hsa-miR-4422	CLIP-seq
MIRT1191869	hsa-miR-4433	CLIP-seq
MIRT1191940	hsa-miR-4436b-3p	CLIP-seq
MIRT1191941	hsa-miR-4441	CLIP-seq
MIRT1191870	hsa-miR-4458	CLIP-seq
MIRT1191871	hsa-miR-4459	CLIP-seq
MIRT1191872	hsa-miR-4478	CLIP-seq
MIRT1191873	hsa-miR-4482	CLIP-seq
MIRT1191876	hsa-miR-4500	CLIP-seq
MIRT1191878	hsa-miR-4521	CLIP-seq
MIRT1191942	hsa-miR-4537	CLIP-seq
MIRT1191881	hsa-miR-4645-5p	CLIP-seq
MIRT1191943	hsa-miR-4653-5p	CLIP-seq
MIRT1191944	hsa-miR-4659a-5p	CLIP-seq
MIRT1191945	hsa-miR-4659b-5p	CLIP-seq
MIRT1191883	hsa-miR-4673	CLIP-seq
MIRT1191946	hsa-miR-4722-5p	CLIP-seq
MIRT1191947	hsa-miR-4727-5p	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191891	hsa-miR-4736	CLIP-seq
MIRT1191948	hsa-miR-4755-5p	CLIP-seq
MIRT1191949	hsa-miR-4761-3p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191950	hsa-miR-4769-3p	CLIP-seq
MIRT1191951	hsa-miR-4786-5p	CLIP-seq
MIRT1191952	hsa-miR-4793-3p	CLIP-seq
MIRT1191953	hsa-miR-4797-5p	CLIP-seq
MIRT1191900	hsa-miR-485-5p	CLIP-seq
MIRT1191954	hsa-miR-490-3p	CLIP-seq
MIRT1191955	hsa-miR-508-5p	CLIP-seq
MIRT1191904	hsa-miR-544b	CLIP-seq
MIRT1191956	hsa-miR-548ac	CLIP-seq
MIRT1191957	hsa-miR-548ae	CLIP-seq
MIRT1191958	hsa-miR-548aj	CLIP-seq
MIRT1191959	hsa-miR-548am	CLIP-seq
MIRT1191960	hsa-miR-548d-3p	CLIP-seq
MIRT1191961	hsa-miR-548x	CLIP-seq
MIRT1191962	hsa-miR-548z	CLIP-seq
MIRT1191963	hsa-miR-555	CLIP-seq
MIRT1191964	hsa-miR-622	CLIP-seq
MIRT1191965	hsa-miR-623	CLIP-seq
MIRT1191966	hsa-miR-633	CLIP-seq
MIRT1191967	hsa-miR-650	CLIP-seq
MIRT1191968	hsa-miR-659	CLIP-seq
MIRT1191969	hsa-miR-661	CLIP-seq
MIRT1191970	hsa-miR-671-5p	CLIP-seq
MIRT1191971	hsa-miR-766	CLIP-seq
MIRT1191972	hsa-miR-769-5p	CLIP-seq
MIRT1191973	hsa-miR-802	CLIP-seq
MIRT1191909	hsa-miR-875-3p	CLIP-seq
MIRT1191974	hsa-miR-940	CLIP-seq
MIRT1191975	hsa-miR-942	CLIP-seq
MIRT1191910	hsa-miR-98	CLIP-seq
MIRT1191976	hsa-miR-1236	CLIP-seq
MIRT1191977	hsa-miR-4778-3p	CLIP-seq
MIRT1191978	hsa-miR-501-3p	CLIP-seq
MIRT1191979	hsa-miR-502-3p	CLIP-seq
MIRT1191980	hsa-miR-767-5p	CLIP-seq
MIRT1191914	hsa-miR-1237	CLIP-seq
MIRT1551866	hsa-miR-186	CLIP-seq
MIRT1551867	hsa-miR-3133	CLIP-seq
MIRT1191912	hsa-miR-1228	CLIP-seq
MIRT1191914	hsa-miR-1237	CLIP-seq
MIRT1191833	hsa-miR-1254	CLIP-seq
MIRT2055630	hsa-miR-1279	CLIP-seq
MIRT1191919	hsa-miR-1827	CLIP-seq
MIRT1191840	hsa-miR-1912	CLIP-seq
MIRT1191926	hsa-miR-2467-3p	CLIP-seq
MIRT2055631	hsa-miR-25	CLIP-seq
MIRT1191845	hsa-miR-3116	CLIP-seq
MIRT1191847	hsa-miR-3130-5p	CLIP-seq
MIRT1191931	hsa-miR-3192	CLIP-seq
MIRT2055632	hsa-miR-32	CLIP-seq
MIRT1191932	hsa-miR-3612	CLIP-seq
MIRT2055633	hsa-miR-363	CLIP-seq
MIRT2055634	hsa-miR-3647-3p	CLIP-seq
MIRT2055635	hsa-miR-367	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT1191935	hsa-miR-3938	CLIP-seq
MIRT1191862	hsa-miR-3978	CLIP-seq
MIRT1191936	hsa-miR-4257	CLIP-seq
MIRT1191937	hsa-miR-4270	CLIP-seq
MIRT1191939	hsa-miR-4422	CLIP-seq
MIRT1191869	hsa-miR-4433	CLIP-seq
MIRT1191941	hsa-miR-4441	CLIP-seq
MIRT1191871	hsa-miR-4459	CLIP-seq
MIRT1191873	hsa-miR-4482	CLIP-seq
MIRT1191942	hsa-miR-4537	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT1191948	hsa-miR-4755-5p	CLIP-seq
MIRT2055636	hsa-miR-4766-5p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191952	hsa-miR-4793-3p	CLIP-seq
MIRT1191954	hsa-miR-490-3p	CLIP-seq
MIRT1191955	hsa-miR-508-5p	CLIP-seq
MIRT1191906	hsa-miR-548g	CLIP-seq
MIRT1191963	hsa-miR-555	CLIP-seq
MIRT1191967	hsa-miR-650	CLIP-seq
MIRT1191969	hsa-miR-661	CLIP-seq
MIRT1191970	hsa-miR-671-5p	CLIP-seq
MIRT1191971	hsa-miR-766	CLIP-seq
MIRT1191909	hsa-miR-875-3p	CLIP-seq
MIRT2055637	hsa-miR-92a	CLIP-seq
MIRT2055638	hsa-miR-92b	CLIP-seq
MIRT1191823	hsa-let-7a	CLIP-seq
MIRT1191824	hsa-let-7b	CLIP-seq
MIRT1191825	hsa-let-7c	CLIP-seq
MIRT1191826	hsa-let-7d	CLIP-seq
MIRT1191827	hsa-let-7e	CLIP-seq
MIRT1191828	hsa-let-7f	CLIP-seq
MIRT1191829	hsa-let-7g	CLIP-seq
MIRT1191830	hsa-let-7i	CLIP-seq
MIRT1191912	hsa-miR-1228	CLIP-seq
MIRT1191914	hsa-miR-1237	CLIP-seq
MIRT1191915	hsa-miR-1248	CLIP-seq
MIRT1191833	hsa-miR-1254	CLIP-seq
MIRT1191918	hsa-miR-1296	CLIP-seq
MIRT1191920	hsa-miR-194	CLIP-seq
MIRT1191841	hsa-miR-202	CLIP-seq
MIRT1191921	hsa-miR-204	CLIP-seq
MIRT1191923	hsa-miR-211	CLIP-seq
MIRT1191927	hsa-miR-2909	CLIP-seq
MIRT1191845	hsa-miR-3116	CLIP-seq
MIRT1191846	hsa-miR-3122	CLIP-seq
MIRT1191851	hsa-miR-3165	CLIP-seq
MIRT1191855	hsa-miR-3622a-3p	CLIP-seq
MIRT1191856	hsa-miR-3622b-3p	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT1191860	hsa-miR-3913-5p	CLIP-seq
MIRT1191933	hsa-miR-3921	CLIP-seq
MIRT1191934	hsa-miR-3927	CLIP-seq
MIRT1191861	hsa-miR-3929	CLIP-seq
MIRT1191935	hsa-miR-3938	CLIP-seq
MIRT1191862	hsa-miR-3978	CLIP-seq
MIRT1191865	hsa-miR-4269	CLIP-seq
MIRT1191937	hsa-miR-4270	CLIP-seq
MIRT1191938	hsa-miR-4303	CLIP-seq
MIRT1191868	hsa-miR-4419b	CLIP-seq
MIRT1191939	hsa-miR-4422	CLIP-seq
MIRT1191869	hsa-miR-4433	CLIP-seq
MIRT1191940	hsa-miR-4436b-3p	CLIP-seq
MIRT1191941	hsa-miR-4441	CLIP-seq
MIRT1191870	hsa-miR-4458	CLIP-seq
MIRT1191871	hsa-miR-4459	CLIP-seq
MIRT1191872	hsa-miR-4478	CLIP-seq
MIRT1191876	hsa-miR-4500	CLIP-seq
MIRT1191877	hsa-miR-4514	CLIP-seq
MIRT1191942	hsa-miR-4537	CLIP-seq
MIRT2284511	hsa-miR-4633-5p	CLIP-seq
MIRT1191943	hsa-miR-4653-5p	CLIP-seq
MIRT1191884	hsa-miR-4684-5p	CLIP-seq
MIRT1191885	hsa-miR-4692	CLIP-seq
MIRT1191947	hsa-miR-4727-5p	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191890	hsa-miR-4729	CLIP-seq
MIRT1191891	hsa-miR-4736	CLIP-seq
MIRT1191892	hsa-miR-4742-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT1191948	hsa-miR-4755-5p	CLIP-seq
MIRT1191949	hsa-miR-4761-3p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191952	hsa-miR-4793-3p	CLIP-seq
MIRT1191900	hsa-miR-485-5p	CLIP-seq
MIRT1191955	hsa-miR-508-5p	CLIP-seq
MIRT1191904	hsa-miR-544b	CLIP-seq
MIRT1191956	hsa-miR-548ac	CLIP-seq
MIRT1191957	hsa-miR-548ae	CLIP-seq
MIRT1191958	hsa-miR-548aj	CLIP-seq
MIRT1191959	hsa-miR-548am	CLIP-seq
MIRT1191905	hsa-miR-548c-3p	CLIP-seq
MIRT1191960	hsa-miR-548d-3p	CLIP-seq
MIRT1191961	hsa-miR-548x	CLIP-seq
MIRT1191962	hsa-miR-548z	CLIP-seq
MIRT1191963	hsa-miR-555	CLIP-seq
MIRT1191964	hsa-miR-622	CLIP-seq
MIRT1191965	hsa-miR-623	CLIP-seq
MIRT2284512	hsa-miR-642a	CLIP-seq
MIRT1191969	hsa-miR-661	CLIP-seq
MIRT1191970	hsa-miR-671-5p	CLIP-seq
MIRT1191971	hsa-miR-766	CLIP-seq
MIRT1191909	hsa-miR-875-3p	CLIP-seq
MIRT1191975	hsa-miR-942	CLIP-seq
MIRT1191910	hsa-miR-98	CLIP-seq
MIRT2465744	hsa-miR-3691-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT1191823	hsa-let-7a	CLIP-seq
MIRT1191824	hsa-let-7b	CLIP-seq
MIRT1191825	hsa-let-7c	CLIP-seq
MIRT1191826	hsa-let-7d	CLIP-seq
MIRT1191827	hsa-let-7e	CLIP-seq
MIRT1191828	hsa-let-7f	CLIP-seq
MIRT1191829	hsa-let-7g	CLIP-seq
MIRT1191830	hsa-let-7i	CLIP-seq
MIRT1191831	hsa-miR-1207-5p	CLIP-seq
MIRT1191916	hsa-miR-1287	CLIP-seq
MIRT2582359	hsa-miR-129-3p	CLIP-seq
MIRT2582360	hsa-miR-1321	CLIP-seq
MIRT2582361	hsa-miR-1825	CLIP-seq
MIRT1191919	hsa-miR-1827	CLIP-seq
MIRT1551866	hsa-miR-186	CLIP-seq
MIRT1191841	hsa-miR-202	CLIP-seq
MIRT1191928	hsa-miR-2964a-3p	CLIP-seq
MIRT1191929	hsa-miR-302f	CLIP-seq
MIRT1191846	hsa-miR-3122	CLIP-seq
MIRT2582362	hsa-miR-3125	CLIP-seq
MIRT1551867	hsa-miR-3133	CLIP-seq
MIRT1191930	hsa-miR-3135b	CLIP-seq
MIRT2582363	hsa-miR-3162-5p	CLIP-seq
MIRT1191931	hsa-miR-3192	CLIP-seq
MIRT1191932	hsa-miR-3612	CLIP-seq
MIRT1191855	hsa-miR-3622a-3p	CLIP-seq
MIRT1191856	hsa-miR-3622b-3p	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT2465744	hsa-miR-3691-5p	CLIP-seq
MIRT1191860	hsa-miR-3913-5p	CLIP-seq
MIRT2582364	hsa-miR-3916	CLIP-seq
MIRT2582365	hsa-miR-3926	CLIP-seq
MIRT1191861	hsa-miR-3929	CLIP-seq
MIRT2582366	hsa-miR-3935	CLIP-seq
MIRT1191865	hsa-miR-4269	CLIP-seq
MIRT1191868	hsa-miR-4419b	CLIP-seq
MIRT1191870	hsa-miR-4458	CLIP-seq
MIRT1191872	hsa-miR-4478	CLIP-seq
MIRT1191876	hsa-miR-4500	CLIP-seq
MIRT1191877	hsa-miR-4514	CLIP-seq
MIRT2582367	hsa-miR-4649-3p	CLIP-seq
MIRT1191882	hsa-miR-4662a-5p	CLIP-seq
MIRT1191884	hsa-miR-4684-5p	CLIP-seq
MIRT2582368	hsa-miR-4687-5p	CLIP-seq
MIRT1191885	hsa-miR-4692	CLIP-seq
MIRT1191946	hsa-miR-4722-5p	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191891	hsa-miR-4736	CLIP-seq
MIRT2582369	hsa-miR-4739	CLIP-seq
MIRT1191892	hsa-miR-4742-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT2582370	hsa-miR-4756-5p	CLIP-seq
MIRT1191896	hsa-miR-4763-3p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191951	hsa-miR-4786-5p	CLIP-seq
MIRT1191900	hsa-miR-485-5p	CLIP-seq
MIRT1191954	hsa-miR-490-3p	CLIP-seq
MIRT2582371	hsa-miR-494	CLIP-seq
MIRT2582372	hsa-miR-532-5p	CLIP-seq
MIRT1191904	hsa-miR-544b	CLIP-seq
MIRT2582373	hsa-miR-548a-3p	CLIP-seq
MIRT2582374	hsa-miR-548aa	CLIP-seq
MIRT1191956	hsa-miR-548ac	CLIP-seq
MIRT1191905	hsa-miR-548c-3p	CLIP-seq
MIRT1191960	hsa-miR-548d-3p	CLIP-seq
MIRT2582375	hsa-miR-548e	CLIP-seq
MIRT2582376	hsa-miR-548f	CLIP-seq
MIRT1191906	hsa-miR-548g	CLIP-seq
MIRT2582377	hsa-miR-548p	CLIP-seq
MIRT2582378	hsa-miR-548s	CLIP-seq
MIRT1191962	hsa-miR-548z	CLIP-seq
MIRT2582379	hsa-miR-566	CLIP-seq
MIRT2582380	hsa-miR-583	CLIP-seq
MIRT1191967	hsa-miR-650	CLIP-seq
MIRT1191972	hsa-miR-769-5p	CLIP-seq
MIRT1191974	hsa-miR-940	CLIP-seq
MIRT1191910	hsa-miR-98	CLIP-seq
MIRT1191823	hsa-let-7a	CLIP-seq
MIRT1191824	hsa-let-7b	CLIP-seq
MIRT1191825	hsa-let-7c	CLIP-seq
MIRT1191826	hsa-let-7d	CLIP-seq
MIRT1191827	hsa-let-7e	CLIP-seq
MIRT1191828	hsa-let-7f	CLIP-seq
MIRT1191829	hsa-let-7g	CLIP-seq
MIRT1191830	hsa-let-7i	CLIP-seq
MIRT1191831	hsa-miR-1207-5p	CLIP-seq
MIRT1191912	hsa-miR-1228	CLIP-seq
MIRT1191916	hsa-miR-1287	CLIP-seq
MIRT2582359	hsa-miR-129-3p	CLIP-seq
MIRT2582360	hsa-miR-1321	CLIP-seq
MIRT1191919	hsa-miR-1827	CLIP-seq
MIRT1551866	hsa-miR-186	CLIP-seq
MIRT1191920	hsa-miR-194	CLIP-seq
MIRT1191841	hsa-miR-202	CLIP-seq
MIRT1191926	hsa-miR-2467-3p	CLIP-seq
MIRT1191928	hsa-miR-2964a-3p	CLIP-seq
MIRT1191929	hsa-miR-302f	CLIP-seq
MIRT1191846	hsa-miR-3122	CLIP-seq
MIRT2686523	hsa-miR-3124-3p	CLIP-seq
MIRT2582362	hsa-miR-3125	CLIP-seq
MIRT1551867	hsa-miR-3133	CLIP-seq
MIRT1191930	hsa-miR-3135b	CLIP-seq
MIRT2582363	hsa-miR-3162-5p	CLIP-seq
MIRT1191931	hsa-miR-3192	CLIP-seq
MIRT1191932	hsa-miR-3612	CLIP-seq
MIRT1191855	hsa-miR-3622a-3p	CLIP-seq
MIRT1191856	hsa-miR-3622b-3p	CLIP-seq
MIRT2686524	hsa-miR-3677-5p	CLIP-seq
MIRT1191858	hsa-miR-3689a-3p	CLIP-seq
MIRT1191859	hsa-miR-3689c	CLIP-seq
MIRT2465744	hsa-miR-3691-5p	CLIP-seq
MIRT1191860	hsa-miR-3913-5p	CLIP-seq
MIRT2582364	hsa-miR-3916	CLIP-seq
MIRT1191861	hsa-miR-3929	CLIP-seq
MIRT2582366	hsa-miR-3935	CLIP-seq
MIRT1191936	hsa-miR-4257	CLIP-seq
MIRT1191865	hsa-miR-4269	CLIP-seq
MIRT1191868	hsa-miR-4419b	CLIP-seq
MIRT1191869	hsa-miR-4433	CLIP-seq
MIRT2686525	hsa-miR-4446-5p	CLIP-seq
MIRT1191870	hsa-miR-4458	CLIP-seq
MIRT1191871	hsa-miR-4459	CLIP-seq
MIRT1191872	hsa-miR-4478	CLIP-seq
MIRT1191876	hsa-miR-4500	CLIP-seq
MIRT1191877	hsa-miR-4514	CLIP-seq
MIRT2686526	hsa-miR-451b	CLIP-seq
MIRT1191942	hsa-miR-4537	CLIP-seq
MIRT2582367	hsa-miR-4649-3p	CLIP-seq
MIRT1191882	hsa-miR-4662a-5p	CLIP-seq
MIRT1191884	hsa-miR-4684-5p	CLIP-seq
MIRT2582368	hsa-miR-4687-5p	CLIP-seq
MIRT1191885	hsa-miR-4692	CLIP-seq
MIRT2686527	hsa-miR-4696	CLIP-seq
MIRT1191946	hsa-miR-4722-5p	CLIP-seq
MIRT1191889	hsa-miR-4728-5p	CLIP-seq
MIRT1191891	hsa-miR-4736	CLIP-seq
MIRT2582369	hsa-miR-4739	CLIP-seq
MIRT1191892	hsa-miR-4742-5p	CLIP-seq
MIRT1191894	hsa-miR-4752	CLIP-seq
MIRT1191948	hsa-miR-4755-5p	CLIP-seq
MIRT2582370	hsa-miR-4756-5p	CLIP-seq
MIRT2686528	hsa-miR-4757-5p	CLIP-seq
MIRT1191896	hsa-miR-4763-3p	CLIP-seq
MIRT1191897	hsa-miR-4768-3p	CLIP-seq
MIRT1191952	hsa-miR-4793-3p	CLIP-seq
MIRT1191900	hsa-miR-485-5p	CLIP-seq
MIRT1191954	hsa-miR-490-3p	CLIP-seq
MIRT2582371	hsa-miR-494	CLIP-seq
MIRT1191955	hsa-miR-508-5p	CLIP-seq
MIRT2582372	hsa-miR-532-5p	CLIP-seq
MIRT1191904	hsa-miR-544b	CLIP-seq
MIRT2582373	hsa-miR-548a-3p	CLIP-seq
MIRT2582374	hsa-miR-548aa	CLIP-seq
MIRT1191956	hsa-miR-548ac	CLIP-seq
MIRT1191905	hsa-miR-548c-3p	CLIP-seq
MIRT1191960	hsa-miR-548d-3p	CLIP-seq
MIRT2582375	hsa-miR-548e	CLIP-seq
MIRT2582376	hsa-miR-548f	CLIP-seq
MIRT1191906	hsa-miR-548g	CLIP-seq
MIRT2582377	hsa-miR-548p	CLIP-seq
MIRT1191962	hsa-miR-548z	CLIP-seq
MIRT1191963	hsa-miR-555	CLIP-seq
MIRT2582379	hsa-miR-566	CLIP-seq
MIRT2582380	hsa-miR-583	CLIP-seq
MIRT1191967	hsa-miR-650	CLIP-seq
MIRT1191969	hsa-miR-661	CLIP-seq
MIRT1191971	hsa-miR-766	CLIP-seq
MIRT1191974	hsa-miR-940	CLIP-seq
MIRT1191910	hsa-miR-98	CLIP-seq

Show/Hide all (13)

Transcription factor	Regulation	Reference
ESR1	Repression	20623181
FOS	Unknown	8004128
JUN	Unknown	11035254;8004128
JUNB	Unknown	11035254
JUND	Unknown	11035254
MAFG	Unknown	11013233
MAFK	Unknown	11013233
NFE2L1	Activation	11013233
NFE2L2	Activation	11013233
NFE2L2	Repression	22459801
NFE2L2	Unknown	11035254
NRF1	Unknown	11035254
SIRT1	Repression	20623181

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003955	Function	NAD(P)H dehydrogenase (quinone) activity	IBA
GO:0003955	Function	NAD(P)H dehydrogenase (quinone) activity	IEA
GO:0003955	Function	NAD(P)H dehydrogenase (quinone) activity	TAS	10393963
GO:0004128	Function	Cytochrome-b5 reductase activity, acting on NAD(P)H	TAS	9579781
GO:0005515	Function	Protein binding	IPI	15687255, 18388957, 21636573, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	2843525
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	10945627
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006743	Process	Ubiquinone metabolic process	IDA	9271353
GO:0006805	Process	Xenobiotic metabolic process	TAS	10393963
GO:0006809	Process	Nitric oxide biosynthetic process	TAS	9579781
GO:0006979	Process	Response to oxidative stress	IEA
GO:0006979	Process	Response to oxidative stress	IEA
GO:0006979	Process	Response to oxidative stress	IEP	21636573
GO:0007271	Process	Synaptic transmission, cholinergic	TAS	9579781
GO:0008753	Function	NADPH dehydrogenase (quinone) activity	IEA
GO:0009636	Process	Response to toxic substance	TAS	10393963
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0019430	Process	Removal of superoxide radicals	IDA	15102952
GO:0030163	Process	Protein catabolic process	IEA
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0034599	Process	Cellular response to oxidative stress	IDA	15687255
GO:0042177	Process	Negative regulation of protein catabolic process	IDA	15687255
GO:0042360	Process	Vitamin E metabolic process	IDA	9271353
GO:0042373	Process	Vitamin K metabolic process	IDA	8999809
GO:0042373	Process	Vitamin K metabolic process	IEA
GO:0042802	Function	Identical protein binding	IPI	25143260
GO:0045087	Process	Innate immune response	IEA
GO:0045202	Component	Synapse	IEA
GO:0045454	Process	Cell redox homeostasis	IEP	21636573
GO:0050136	Function	NADH dehydrogenase (quinone) (non-electrogenic) activity	IDA	8999809, 9271353
GO:0050136	Function	NADH dehydrogenase (quinone) (non-electrogenic) activity	IEA
GO:0061771	Process	Response to caloric restriction	IEA
GO:0110076	Process	Negative regulation of ferroptosis	IMP	26403645

MIM	HGNC	e!Ensembl
125860	2874	ENSG00000181019

P15559

Protein name

NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Azoreductase) (DT-diaphorase) (DTD) (Menadione reductase) (NAD(P)H:quinone oxidoreductase 1) (Phylloquinone reductase) (Quinone reductase 1) (QR1)

Protein function

Flavin-containing quinone reductase that catalyzes two-electron reduction of quinones to hydroquinones using either NADH or NADPH as electron donors. In a ping-pong kinetic mechanism, the electrons are sequentially transferred from NAD(P)H to fl

PDB

1D4A , 1DXO , 1GG5 , 1H66 , 1H69 , 1KBO , 1KBQ , 1QBG , 2F1O , 3JSX , 4CET , 4CF6 , 5A4K , 5EA2 , 5EAI , 5FUQ , 6FY4 , 6LLC , 8C9J , 8OK0 , 8PQN , 8RFM , 8RFN

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02525	Flavodoxin_2	4 → 212	Flavodoxin-like fold	Domain

Sequence

MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK

Sequence length

274

Interactions

View interactions

	KEGG		Reactome
	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways Biosynthesis of cofactors Pathways in cancer Chemical carcinogenesis - reactive oxygen species Hepatocellular carcinoma Fluid shear stress and atherosclerosis		Regulation of ornithine decarboxylase (ODC)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Benzene toxicity, susceptibility to	Uncertain significance	rs1800566	RCV000018300
NQO1-related disorder	Likely benign; Uncertain significance; Benign	rs762495795, rs1800566, rs534337407, rs689453	RCV003916465 RCV003974839 RCV003934538 RCV003976284

Show/Hide Text Mining Associations (133)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute erythroleukemia	Associate	17339179
Acute Lung Injury	Associate	19017358, 36555290
Adenocarcinoma	Associate	25880877, 26625776, 26683690, 7669561
Adenoma	Associate	23840148
Adenoma Pleomorphic	Associate	25928388
Agranulocytosis	Associate	40311769
Alzheimer Disease	Associate	21220432
Anophthalmia with pulmonary hypoplasia	Associate	32633891
Asthma	Associate	16385446, 20049212, 20526719, 23066387, 31539146
Atrial Fibrillation	Associate	29776386
Brain Neoplasms	Associate	32526700
Breast Neoplasms	Associate	11279125, 12750552, 15138483, 18416817, 19657853, 23249637, 23883585, 23897704, 24499631, 24789723, 27039751, 27966538, 28411284, 30513573, 30935019, 30954648, 32922184, 35617355, 9328153 View all (4 more)
Bronchopulmonary Dysplasia	Associate	25518008
Cap Myopathy	Associate	26987799
Carcinogenesis	Associate	18416817, 21480392, 23480754, 24499631, 25125658, 26078718, 37594082
Carcinoma Basal Cell	Associate	27057281, 35501667
Carcinoma Hepatocellular	Associate	22972504, 24278187, 31842909, 31968140, 33083480, 33162398, 36582227, 37695786, 37986299, 40611075
Carcinoma Non Small Cell Lung	Associate	21479364, 21964527, 24924344, 25222473, 25880877, 26625776, 28501854, 31899687, 34035487, 36980879, 9000600
Carcinoma Non Small Cell Lung	Stimulate	36359002
Carcinoma Pancreatic Ductal	Associate	25590809, 35180880
Carcinoma Small Cell	Associate	10206277
Carcinoma Squamous Cell	Associate	22984577, 24912939, 25729241, 25880877, 31886179, 35501667
Cardiovascular Diseases	Associate	21479364, 28785379, 36012132
Cartilage Diseases	Associate	29339024
Cell Transformation Neoplastic	Associate	27966538
Cerebral Infarction	Associate	39174970
Cholangiocarcinoma	Associate	18820947, 20480521, 21577322, 23480754, 24460787, 29914576, 30584780
Cholangitis Sclerosing	Associate	29180269
Chromosome Aberrations	Associate	10397748
Chronic Kidney Disease Mineral and Bone Disorder	Stimulate	32291269
Chronic Traumatic Encephalopathy	Associate	29145658
Colonic Diseases	Associate	24912939
Colonic Neoplasms	Associate	18618519, 9000600, 9818026
Colorectal Neoplasms	Associate	10391098, 20593958, 24695690, 27860235, 27966538, 28236663, 34356648, 9818026
COVID 19	Associate	37301869
Diabetes Gestational	Associate	23974919
Diabetes Mellitus	Associate	22445099, 27274779
Drug Related Side Effects and Adverse Reactions	Associate	10681517, 17574288, 19628038, 20480521, 21964527, 23229783, 24505400, 31527169, 32922184, 40311769
Dyskinesia Drug Induced	Associate	15151706
Emanuel syndrome	Associate	12393620
Endometrial Neoplasms	Associate	28748640, 30908539
Esophageal Neoplasms	Associate	12854127
Esophageal Squamous Cell Carcinoma	Associate	12854127, 20198579, 22853296, 24886060, 35194221
Essential Hypertension	Associate	27977510
Fuchs' Endothelial Dystrophy	Associate	29294389, 31857234
Gastrointestinal Neoplasms	Associate	12854127
Glioblastoma	Stimulate	10639573, 33087132
Glioblastoma	Associate	30595797, 32526700, 37594082
Glioma	Associate	35396498
Hepatitis B Chronic	Associate	27390784
Hepatitis C Chronic	Associate	30929321
Hereditary Breast and Ovarian Cancer Syndrome	Associate	10681517, 25885439, 27966538, 36234741
Hypertriglyceridemia	Associate	25933176
hypoglycemic encephalopathy	Inhibit	25807533
Hypoxia	Associate	30867055
Hypoxia Brain	Associate	8065332
Ichthyosis Vulgaris	Stimulate	20664557
Inflammation	Inhibit	18820947, 39174970
Inflammation	Associate	25125658, 26410779, 30336658, 36012132, 36555290
Intervertebral Disc Degeneration	Associate	36817437
Intestinal Diseases	Associate	19822020
Isodicentric Chromosome 15 Syndrome	Associate	11222389, 23066397
Kidney Diseases	Inhibit	37681897
Laryngeal Neoplasms	Associate	27840932
Leukemia	Associate	10397748, 12393620, 20378716, 26870816
Leukemia Lymphocytic Chronic B Cell	Associate	31992855, 35845961
Leukemia Lymphoma Adult T Cell	Associate	12393620
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	10397748, 16235982
Leukemia Myeloid	Associate	10397748, 20378716
Leukemia Myeloid Acute	Associate	10397748, 11222389, 12468438, 15198733, 17339179, 17367411, 23066397
Leukemia T Cell	Associate	24571676
Liver Cirrhosis	Associate	27390784
Liver Cirrhosis Biliary	Stimulate	16610002
Liver Failure	Associate	16610002, 27390784, 33162398
Lung Diseases	Associate	36234741
Lung Neoplasms	Associate	17496311, 19174490, 23947958, 25222473, 25729241, 25880877, 36359002
Lymphatic Metastasis	Associate	24499631, 24912939, 25880877, 30954648
Lymphoma	Associate	9579829
Macular Degeneration	Associate	23276910
Melanoma	Associate	24912939, 27045471, 30989459, 35255427
Melanoma Cutaneous Malignant	Associate	35232428
Metabolic Diseases	Associate	25933176, 38406838
Metabolic Syndrome	Associate	25933176
Mitochondrial Diseases	Associate	23874855, 38599881
Motor Neuron Disease	Associate	38599881
Multiple Sclerosis	Associate	24755231
Myelodysplastic Syndromes	Associate	10397748, 15198733, 17367411
Nasopharyngeal Carcinoma	Associate	30160047
Necrosis	Associate	22532167, 30318513
Neoplasm Metastasis	Associate	30954648, 31968140
Neoplasm Metastasis	Stimulate	37594082
Neoplasms	Associate	10376975, 10748880, 11821413, 12718704, 17574288, 18024413, 20198579, 20593958, 20613985, 21133623, 21378203, 21479364, 21577322, 22532167, 22972504 View all (45 more)
Neoplasms	Stimulate	11587640, 23883585
Neoplasms	Inhibit	26987799, 31886179, 34833955
Nerve Degeneration	Associate	23874855
Neuroblastoma	Associate	14985350, 23874855
Non alcoholic Fatty Liver Disease	Associate	20805291
Non Muscle Invasive Bladder Neoplasms	Associate	34549902
Obesity	Associate	23975165, 26856346, 27274779
Oncogene Addiction	Stimulate	26078718
Osteoarthritis	Associate	28237856, 29339024
Osteoglophonic dwarfism	Associate	32319645
Ovarian Neoplasms	Associate	21480392, 25885439
Overweight	Stimulate	26856346
Pancreatic Neoplasms	Associate	16003741, 22984577, 28346693, 28916726, 30954648, 31526948, 32537471, 33214574, 34732125
Papillary Thyroid Microcarcinoma	Associate	23918565
Papillomavirus Infections	Associate	24912939, 32443295
Periodic fever familial autosomal dominant	Associate	31568004
Polycystic Ovary Syndrome	Stimulate	28748640
Precancerous Conditions	Associate	11587640
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	12393620, 17332311, 18024413
Prodromal Symptoms	Associate	21479364
Progeria	Associate	28229933
Prostatic Neoplasms	Associate	18225579, 23109831, 25125658, 29697282
Prostatitis	Associate	23109831, 25125658
Pulmonary Disease Chronic Obstructive	Associate	35441963
Renal Insufficiency Chronic	Stimulate	28785379
Retinoblastoma	Associate	31207142
Rhabdoid Tumor	Associate	20212451
Sarcoma	Associate	34982796
Small Cell Lung Carcinoma	Associate	21964527, 25400754
Smoke Inhalation Injury	Associate	12718704, 25729241
Stomach Neoplasms	Associate	10376975, 12854127, 19822020, 21931799, 25545243, 34168410
Triple Negative Breast Neoplasms	Associate	23883585, 32922184
Uremia	Stimulate	28785379
Urethral Neoplasms	Associate	17619904
Urinary Bladder Neoplasms	Associate	24219772, 24315573, 34549902
Uterine Cervical Dysplasia	Associate	16003741
Uterine Cervical Neoplasms	Associate	20200430, 23534750, 24912939, 32443295
Uterine Cervicitis	Associate	24912939
Uterine Diseases	Associate	33678318
Venous Thromboembolism	Associate	37762110
Wounds and Injuries	Associate	19017358

NQO1 (NAD(P)H quinone dehydrogenase 1)