PSORS1C1 (psoriasis susceptibility 1 candidate 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
170679
Gene name Gene Name - the full gene name approved by the HGNC.
Psoriasis susceptibility 1 candidate 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PSORS1C1
Synonyms (NCBI Gene) Gene synonyms aliases
C6orf16, SEEK1
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p21.33
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. [provided by RefSeq, Sep 2011]
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT016974 hsa-miR-335-5p Microarray 18185580
MIRT016974 hsa-miR-335-5p Microarray 18185580
MIRT2079731 hsa-miR-4514 CLIP-seq
MIRT2079732 hsa-miR-4645-5p CLIP-seq
MIRT2079733 hsa-miR-4673 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(1)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
613525 17202 ENSG00000204540
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9UIG5
Protein name Psoriasis susceptibility 1 candidate gene 1 protein (Protein SEEK1)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15357 SEEK1 4 → 152 Psoriasis susceptibility 1 candidate 1 Family
Tissue specificity TISSUE SPECIFICITY: Expressed in skin. Also found in heart, placenta, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:12930300}.
Sequence
Sequence length 152
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (12)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Allergic Sensitization Allergic sensitization N/A N/A GWAS
Asthma Adult asthma N/A N/A GWAS
Leprosy Leprosy N/A N/A GWAS
Multiple myeloma Multiple myeloma N/A N/A GWAS
Show/Hide Text Mining Associations (12)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Arthritis Psoriatic Associate 15708881
Arthritis Rheumatoid Associate 27342690, 28107378
Asthma Associate 24406073
Leprosy Associate 32421744
Lung Neoplasms Associate 31518089
Menopause Premature Associate 33860118
Monoclonal Gammopathy of Undetermined Significance Associate 24449210
Multiple Myeloma Associate 24449210
Neoplasms Squamous Cell Associate 31518089
Pulmonary Disease Chronic Obstructive Associate 21949713