PSORS1C1 (psoriasis susceptibility 1 candidate 1)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 170679
Gene name Psoriasis susceptibility 1 candidate 1
Gene symbol PSORS1C1
Synonyms (NCBI Gene)
C6orf16SEEK1
Chromosome 6
Chromosome location 6p21.33
Summary This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. [provided by RefSeq, Sep 2011]
miRNA miRNA information provided by mirtarbase database.
8
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (8)
miRTarBase ID miRNA Experiments Reference
MIRT016974 hsa-miR-335-5p Microarray 18185580
MIRT016974 hsa-miR-335-5p Microarray 18185580
MIRT2079731 hsa-miR-4514 CLIP-seq
MIRT2079732 hsa-miR-4645-5p CLIP-seq
MIRT2079733 hsa-miR-4673 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (1)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
613525 17202 ENSG00000204540
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UIG5
Protein name Psoriasis susceptibility 1 candidate gene 1 protein (Protein SEEK1)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15357 SEEK1 4 → 152 Psoriasis susceptibility 1 candidate 1 Family
Tissue specificity TISSUE SPECIFICITY: Expressed in skin. Also found in heart, placenta, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:12930300}.
Sequence
Sequence length 152
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
PSORS1C1-related disorder Benign; Likely benign rs9263726, rs1063646, rs374244467, rs1265096, rs9501057, rs1265097, rs111892391 RCV003979698
RCV003979756
RCV003911790
RCV003979031
RCV003982005
RCV003982020
RCV003960770
Show/Hide Text Mining Associations (12)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Arthritis Psoriatic Associate 15708881
Arthritis Rheumatoid Associate 27342690, 28107378
Asthma Associate 24406073
Leprosy Associate 32421744
Lung Neoplasms Associate 31518089
Menopause Premature Associate 33860118
Monoclonal Gammopathy of Undetermined Significance Associate 24449210
Multiple Myeloma Associate 24449210
Neoplasms Squamous Cell Associate 31518089
Pulmonary Disease Chronic Obstructive Associate 21949713