Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	169981
Gene name Gene Name - the full gene name approved by the HGNC.	Spindlin family member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SPIN3
Synonyms (NCBI Gene) Gene synonyms aliases	SPIN-3, TDRD27, bA445O16.1
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xp11.21

Show/Hide all(91)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023137	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT645472	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT645471	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT645470	hsa-miR-4301	HITS-CLIP	23824327
MIRT645469	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT645468	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT645467	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT645466	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT645464	hsa-miR-1260a	HITS-CLIP	23824327
MIRT645465	hsa-miR-1260b	HITS-CLIP	23824327
MIRT645463	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT645472	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT645471	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT645470	hsa-miR-4301	HITS-CLIP	23824327
MIRT645469	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT645468	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT645467	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT645466	hsa-miR-188-3p	HITS-CLIP	23824327
MIRT645464	hsa-miR-1260a	HITS-CLIP	23824327
MIRT645465	hsa-miR-1260b	HITS-CLIP	23824327
MIRT645463	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT1384280	hsa-miR-1179	CLIP-seq
MIRT1384281	hsa-miR-1262	CLIP-seq
MIRT1384282	hsa-miR-150	CLIP-seq
MIRT1384283	hsa-miR-2114	CLIP-seq
MIRT1384284	hsa-miR-2355-5p	CLIP-seq
MIRT1384285	hsa-miR-298	CLIP-seq
MIRT1384286	hsa-miR-3136-5p	CLIP-seq
MIRT1384287	hsa-miR-3145-5p	CLIP-seq
MIRT1384288	hsa-miR-3148	CLIP-seq
MIRT1384289	hsa-miR-3616-3p	CLIP-seq
MIRT1384290	hsa-miR-3661	CLIP-seq
MIRT1384291	hsa-miR-378	CLIP-seq
MIRT1384292	hsa-miR-378b	CLIP-seq
MIRT1384293	hsa-miR-378c	CLIP-seq
MIRT1384294	hsa-miR-378d	CLIP-seq
MIRT1384295	hsa-miR-378e	CLIP-seq
MIRT1384296	hsa-miR-378f	CLIP-seq
MIRT1384297	hsa-miR-378h	CLIP-seq
MIRT1384298	hsa-miR-378i	CLIP-seq
MIRT1384299	hsa-miR-422a	CLIP-seq
MIRT1384300	hsa-miR-4436b-3p	CLIP-seq
MIRT1384301	hsa-miR-4439	CLIP-seq
MIRT1384302	hsa-miR-4638-3p	CLIP-seq
MIRT1384303	hsa-miR-4662a-3p	CLIP-seq
MIRT1384304	hsa-miR-4668-5p	CLIP-seq
MIRT1384305	hsa-miR-4687-3p	CLIP-seq
MIRT1384306	hsa-miR-4701-3p	CLIP-seq
MIRT1384307	hsa-miR-4704-5p	CLIP-seq
MIRT1384308	hsa-miR-4712-3p	CLIP-seq
MIRT1384309	hsa-miR-508-5p	CLIP-seq
MIRT1384310	hsa-miR-554	CLIP-seq
MIRT1384311	hsa-miR-626	CLIP-seq
MIRT1384312	hsa-miR-631	CLIP-seq
MIRT1384313	hsa-miR-647	CLIP-seq
MIRT1384314	hsa-miR-943	CLIP-seq
MIRT2115060	hsa-miR-1202	CLIP-seq
MIRT1384283	hsa-miR-2114	CLIP-seq
MIRT2115061	hsa-miR-3194-5p	CLIP-seq
MIRT2115062	hsa-miR-361-5p	CLIP-seq
MIRT2115063	hsa-miR-3972	CLIP-seq
MIRT2115064	hsa-miR-4328	CLIP-seq
MIRT2115065	hsa-miR-450b-5p	CLIP-seq
MIRT2115066	hsa-miR-4691-3p	CLIP-seq
MIRT2115067	hsa-miR-4708-3p	CLIP-seq
MIRT2115068	hsa-miR-507	CLIP-seq
MIRT2115069	hsa-miR-557	CLIP-seq
MIRT2337702	hsa-miR-144	CLIP-seq
MIRT1384285	hsa-miR-298	CLIP-seq
MIRT2337703	hsa-miR-3127-3p	CLIP-seq
MIRT2337704	hsa-miR-3944-5p	CLIP-seq
MIRT2337705	hsa-miR-4270	CLIP-seq
MIRT2337706	hsa-miR-4323	CLIP-seq
MIRT2337707	hsa-miR-4441	CLIP-seq
MIRT2337708	hsa-miR-4676-5p	CLIP-seq
MIRT2337709	hsa-miR-4685-5p	CLIP-seq
MIRT2337710	hsa-miR-4704-3p	CLIP-seq
MIRT2337711	hsa-miR-4709-5p	CLIP-seq
MIRT2337712	hsa-miR-4717-3p	CLIP-seq
MIRT2337713	hsa-miR-4773	CLIP-seq
MIRT2337714	hsa-miR-4786-5p	CLIP-seq
MIRT2337715	hsa-miR-575	CLIP-seq
MIRT2337716	hsa-miR-627	CLIP-seq
MIRT2631255	hsa-miR-132	CLIP-seq
MIRT2631256	hsa-miR-194	CLIP-seq
MIRT2631257	hsa-miR-212	CLIP-seq
MIRT2631258	hsa-miR-3647-3p	CLIP-seq
MIRT2631259	hsa-miR-4490	CLIP-seq
MIRT2631260	hsa-miR-499-3p	CLIP-seq
MIRT2631261	hsa-miR-499a-3p	CLIP-seq
MIRT2631262	hsa-miR-582-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	28514442, 29061846, 33961781
GO:0005654	Component	Nucleoplasm	IBA
GO:0005829	Component	Cytosol	IBA
GO:0006325	Process	Chromatin organization	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0007276	Process	Gamete generation	IEA
GO:0140002	Function	Histone H3K4me3 reader activity	IDA	29061846

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q5JUX0

Protein name

Spindlin-3 (Spindlin-like protein 3) (SPIN-3)

Protein function

Exhibits H3K4me3-binding activity.

PDB

5A1H

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02513	Spin-Ssty	50 → 99	Spin/Ssty Family	Repeat
PF02513	Spin-Ssty	129 → 178	Spin/Ssty Family	Repeat
PF02513	Spin-Ssty	210 → 255	Spin/Ssty Family	Repeat

Sequence

MKTPFGKAAAGQRSRTGAGHGSVSVTMIKRKAAHKKHRSRPTSQPRGNIVGCRIQHGWKD
GDEPLTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHRDERVSSLEVLPNRVASSRIS
DTHLAEIMVGKAVEHIFETEEGSKNEWRGMVLAQAPVMNTWFYITYEKDPVLYMYQLLDD
YKDGDLRILQDSNDSPLAEREPGEVIDSLVGKQVEYAKDDGSKRTGMVIHQVEAKPSVYF
IKFDDDFHIYVYDLVKTS

Sequence length

258

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Hypogonadism	Hypogonadism	N/A	N/A	GWAS
Neuroticism	Neuroticism	N/A	N/A	GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS

SPIN3 (spindlin family member 3)