ZNF169 (zinc finger protein 169)

Gene

• Entrez ID: 169841
• Gene name: Zinc finger protein 169
• Gene symbol: ZNF169
• Synonyms (NCBI Gene): -
• Chromosome: 9
• Chromosome location: 9q22.32

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT1517063	hsa-miR-1204	CLIP-seq
MIRT1517064	hsa-miR-3120-5p	CLIP-seq
MIRT1517065	hsa-miR-3148	CLIP-seq
MIRT1517066	hsa-miR-3190	CLIP-seq
MIRT1517067	hsa-miR-3647-3p	CLIP-seq
MIRT1517068	hsa-miR-3714	CLIP-seq
MIRT1517069	hsa-miR-3978	CLIP-seq
MIRT1517070	hsa-miR-4435	CLIP-seq
MIRT1517071	hsa-miR-4752	CLIP-seq
MIRT1517072	hsa-miR-671-5p	CLIP-seq
MIRT2156115	hsa-miR-148a	CLIP-seq
MIRT2156116	hsa-miR-148b	CLIP-seq
MIRT2156117	hsa-miR-152	CLIP-seq
MIRT2156118	hsa-miR-1827	CLIP-seq
MIRT2156119	hsa-miR-2682	CLIP-seq
MIRT2156120	hsa-miR-298	CLIP-seq
MIRT2156121	hsa-miR-3145-3p	CLIP-seq
MIRT2156122	hsa-miR-34a	CLIP-seq
MIRT2156123	hsa-miR-34c-5p	CLIP-seq
MIRT2156124	hsa-miR-3646	CLIP-seq
MIRT2156125	hsa-miR-4311	CLIP-seq
MIRT2156126	hsa-miR-4316	CLIP-seq
MIRT2156127	hsa-miR-449a	CLIP-seq
MIRT2156128	hsa-miR-449b	CLIP-seq
MIRT2156129	hsa-miR-449c	CLIP-seq
MIRT2375672	hsa-miR-1273e	CLIP-seq
MIRT2375673	hsa-miR-296-5p	CLIP-seq
MIRT2375674	hsa-miR-3672	CLIP-seq
MIRT2375675	hsa-miR-4506	CLIP-seq
MIRT2375676	hsa-miR-450b-3p	CLIP-seq
MIRT2375677	hsa-miR-4713-3p	CLIP-seq
MIRT2375678	hsa-miR-552	CLIP-seq
MIRT2375679	hsa-miR-576-5p	CLIP-seq
MIRT2375680	hsa-miR-638	CLIP-seq
MIRT2375681	hsa-miR-769-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 603404
• HGNC: 12957
• e!Ensembl: ENSG00000175787

Protein

• UniProt ID: Q14929
• Protein name: Zinc finger protein 169
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	13 → 54	KRAB box	Family
  PF00096	zf-C2H2	234 → 256	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	262 → 284	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	290 → 312	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	318 → 340	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	346 → 368	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	374 → 396	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	402 → 424	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	430 → 452	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	458 → 480	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	486 → 508	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	542 → 564	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	570 → 595	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in kidney, weakly expressed in heart, liver, spleen, and small intestine. Not expressed in adult brain or spinal cord.
• Sequence:

  MSPGLLTTRKEALMAFRDVAVAFTQKEWKLLSSAQRTLYREVMLENYSHLVSLGIAFSKP
  KLIEQLEQGDEPWREENEHLLDLCPEPRTEFQPSFPHLVAFSSSQLLRQYALSGHPTQIF
  PSSSAGGDFQLEAPRCSSEKGESGETEGPDSSLRKRPSRISRTFFSPHQGDPVEWVEGNR
  EGGTDLRLAQRMSLGGSDTMLKGADTSESGAVIRGNYRLGLSKKSSLFSHQKHHVCPECG
  RGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYVCRECGRHFR
  YTSSLTNHKRIHSGERPFVCQECGRGFRQKIALLLHQRTHLEEKPFVCPECGRGFCQKAS
  LLQHQSSHTGERPFLCLECGRSFRQQSLLLSHQVTHSGEKPYVCAECGHSFRQKVTLIRH
  QRTHTGEKPYLCPQCGRGFSQKVTLIGHQRTHTGEKPYLCPDCGRGFGQKVTLIRHQRTH
  TGEKPYLCPKCGRAFGFKSLLTRHQRTHSEEELYVDRVCGQGLGQKSHLISDQRTHSGEK
  PCICDECGRGFGFKSALIRHQRTHSGEKPYVCRECGRGFSQKSHLHRHRRTKSGHQLLPQ
  EVF

• Sequence length: 603

Pathways

Reactome:

Generic Transcription Pathway