Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	169841
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 169
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF169
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9q22.32

Show/Hide all(55)

miRTarBase ID	miRNA	Experiments	Reference
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT495561	hsa-miR-5571-5p	PAR-CLIP	22291592
MIRT495562	hsa-miR-3529-3p	PAR-CLIP	22291592
MIRT495560	hsa-miR-1976	PAR-CLIP	22291592
MIRT495559	hsa-miR-376a-3p	PAR-CLIP	22291592
MIRT495558	hsa-miR-376b-3p	PAR-CLIP	22291592
MIRT1517063	hsa-miR-1204	CLIP-seq
MIRT1517064	hsa-miR-3120-5p	CLIP-seq
MIRT1517065	hsa-miR-3148	CLIP-seq
MIRT1517066	hsa-miR-3190	CLIP-seq
MIRT1517067	hsa-miR-3647-3p	CLIP-seq
MIRT1517068	hsa-miR-3714	CLIP-seq
MIRT1517069	hsa-miR-3978	CLIP-seq
MIRT1517070	hsa-miR-4435	CLIP-seq
MIRT1517071	hsa-miR-4752	CLIP-seq
MIRT1517072	hsa-miR-671-5p	CLIP-seq
MIRT2156115	hsa-miR-148a	CLIP-seq
MIRT2156116	hsa-miR-148b	CLIP-seq
MIRT2156117	hsa-miR-152	CLIP-seq
MIRT2156118	hsa-miR-1827	CLIP-seq
MIRT2156119	hsa-miR-2682	CLIP-seq
MIRT2156120	hsa-miR-298	CLIP-seq
MIRT2156121	hsa-miR-3145-3p	CLIP-seq
MIRT2156122	hsa-miR-34a	CLIP-seq
MIRT2156123	hsa-miR-34c-5p	CLIP-seq
MIRT2156124	hsa-miR-3646	CLIP-seq
MIRT2156125	hsa-miR-4311	CLIP-seq
MIRT2156126	hsa-miR-4316	CLIP-seq
MIRT2156127	hsa-miR-449a	CLIP-seq
MIRT2156128	hsa-miR-449b	CLIP-seq
MIRT2156129	hsa-miR-449c	CLIP-seq
MIRT2375672	hsa-miR-1273e	CLIP-seq
MIRT2375673	hsa-miR-296-5p	CLIP-seq
MIRT2375674	hsa-miR-3672	CLIP-seq
MIRT2375675	hsa-miR-4506	CLIP-seq
MIRT2375676	hsa-miR-450b-3p	CLIP-seq
MIRT2375677	hsa-miR-4713-3p	CLIP-seq
MIRT2375678	hsa-miR-552	CLIP-seq
MIRT2375679	hsa-miR-576-5p	CLIP-seq
MIRT2375680	hsa-miR-638	CLIP-seq
MIRT2375681	hsa-miR-769-3p	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA	21873635
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	21873635
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
603404	12957	ENSG00000175787

Protein

UniProt ID

Q14929

Protein name

Zinc finger protein 169

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	13 → 54	KRAB box	Family
PF00096	zf-C2H2	234 → 256	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	262 → 284	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	290 → 312	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	318 → 340	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	346 → 368	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	374 → 396	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	402 → 424	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	430 → 452	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	458 → 480	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	486 → 508	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	542 → 564	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	570 → 595	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in kidney, weakly expressed in heart, liver, spleen, and small intestine. Not expressed in adult brain or spinal cord.

Sequence

MSPGLLTTRKEALMAFRDVAVAFTQKEWKLLSSAQRTLYREVMLENYSHLVSLGIAFSKP
KLIEQLEQGDEPWREENEHLLDLCPEPRTEFQPSFPHLVAFSSSQLLRQYALSGHPTQIF
PSSSAGGDFQLEAPRCSSEKGESGETEGPDSSLRKRPSRISRTFFSPHQGDPVEWVEGNR
EGGTDLRLAQRMSLGGSDTMLKGADTSESGAVIRGNYRLGLSKKSSLFSHQKHHVCPECG
RGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYVCRECGRHFR
YTSSLTNHKRIHSGERPFVCQECGRGFRQKIALLLHQRTHLEEKPFVCPECGRGFCQKAS
LLQHQSSHTGERPFLCLECGRSFRQQSLLLSHQVTHSGEKPYVCAECGHSFRQKVTLIRH
QRTHTGEKPYLCPQCGRGFSQKVTLIGHQRTHTGEKPYLCPDCGRGFGQKVTLIRHQRTH
TGEKPYLCPKCGRAFGFKSLLTRHQRTHSEEELYVDRVCGQGLGQKSHLISDQRTHSGEK
PCICDECGRGFGFKSALIRHQRTHSGEKPYVCRECGRGFSQKSHLHRHRRTKSGHQLLPQ
EVF

Sequence length

603

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Obesity	Obesity	rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562 View all (27 more)	29273807

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Metabolic Syndrome	Metabolic Syndrome			GWAS

ZNF169 (zinc finger protein 169)