DFFA (DNA fragmentation factor subunit alpha)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1676 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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DNA fragmentation factor subunit alpha |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DFFA |
Synonyms (NCBI Gene)
Gene synonyms aliases
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DFF-45, DFF1, ICAD |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p36.22 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal uni |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | O00273 | |||||||||||||||
Protein name | DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) | |||||||||||||||
Protein function | Inhibitor of the caspase-activated DNase (DFF40). | |||||||||||||||
PDB | 1IBX , 1IYR , 1KOY | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 331 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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