DFFA (DNA fragmentation factor subunit alpha)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 1676 |
| Gene name | DNA fragmentation factor subunit alpha |
| Gene symbol | DFFA |
| Synonyms (NCBI Gene) |
DFF-45DFF1ICAD
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| Chromosome | 1 |
| Chromosome location | 1p36.22 |
| Summary | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal uni |
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miRNA
miRNA information provided by mirtarbase database.
777
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O00273 | |||||||||||||||
| Protein name | DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD) | |||||||||||||||
| Protein function | Inhibitor of the caspase-activated DNase (DFF40). | |||||||||||||||
| PDB | 1IBX , 1IYR , 1KOY | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 331 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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