Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
166968
Gene name Gene Name - the full gene name approved by the HGNC.
MIER family member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIER3
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q11.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016054 hsa-miR-374b-5p Sequencing 20371350
MIRT016182 hsa-miR-590-3p Sequencing 20371350
MIRT019243 hsa-miR-331-3p Sequencing 20371350
MIRT021919 hsa-miR-128-3p Sequencing 20371350
MIRT023461 hsa-miR-30b-5p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA
GO:0003714 Function Transcription corepressor activity IBA
GO:0004407 Function Histone deacetylase activity IDA 28046085
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IDA 28046085
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620100 26678 ENSG00000155545
Protein
UniProt ID Q7Z3K6
Protein name Mesoderm induction early response protein 3 (Mi-er3)
Protein function Transcriptional repressor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01448 ELM2 176 226 ELM2 domain Family
PF00249 Myb_DNA-binding 279 325 Myb-like DNA-binding domain Domain
Sequence
MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEMMDEGKNFSSEIEDLEK
EGTMPLEDLLAFYGYEPTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEET
QSSADDLTPSVTSHETSDFFPRPLRSNTACDGDKESEVEDVETDSGNSPEDLRKEIMIGL
QYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLESKVKEYLVETS
LRTGSEKIMDRISA
GTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLFGKD
FHLIQKNKVRTRTVAECVAFYYMWK
KSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDE
TEALGGTVNASALTSNRPEPIPDQQLNILNSFTASDLTALTNSVATVCDPTDVNCLDDSF
PPLGNTPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMNMCSEESERPAK
RLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFISAHA
LHQHAALHSE
Sequence length 550
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Breast cancer Breast cancer, Breast cancer (early onset) N/A N/A GWAS
Breast Cancer Postmenopausal breast cancer N/A N/A GWAS