UBXN2A (UBX domain protein 2A)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 165324 |
| Gene name | UBX domain protein 2A |
| Gene symbol | UBXN2A |
| Synonyms (NCBI Gene) |
UBXD4
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| Chromosome | 2 |
| Chromosome location | 2p23.3 |
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miRNA
miRNA information provided by mirtarbase database.
692
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P68543 | |||||||||||||||
| Protein name | UBX domain-containing protein 2A (UBX domain-containing protein 4) | |||||||||||||||
| Protein function | Acts to repress the ubiquitination and subsequent endoplasmic reticulum-associated degradation of CHRNA3 by the STUB1-VCP-UBXN2A complex in cortical neurons (PubMed:26265139). Also acts to promote the translocation of CHRNA3 to the plasma membra | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in the colon (at protein level). {ECO:0000269|PubMed:37037900}. | |||||||||||||||
| Sequence |
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| Sequence length | 259 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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