TMEM92 (transmembrane protein 92)

Gene

• Entrez ID: 162461
• Gene name: Transmembrane protein 92
• Gene symbol: TMEM92
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q21.33

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs730882247	A>G	Likely-pathogenic	Intron variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT652361	hsa-miR-5196-3p	HITS-CLIP	23824327
MIRT652360	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652359	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652358	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT652357	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT652356	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT652355	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT652354	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT652361	hsa-miR-5196-3p	HITS-CLIP	23824327
MIRT652360	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652359	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652358	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT652357	hsa-miR-2116-3p	HITS-CLIP	23824327
MIRT652356	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT652355	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT652354	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT1439605	hsa-miR-1207-5p	CLIP-seq
MIRT1439606	hsa-miR-1343	CLIP-seq
MIRT1439607	hsa-miR-2392	CLIP-seq
MIRT1439608	hsa-miR-4763-3p	CLIP-seq
MIRT1439609	hsa-miR-1200	CLIP-seq
MIRT1439610	hsa-miR-3187-3p	CLIP-seq
MIRT1439611	hsa-miR-3616-3p	CLIP-seq
MIRT1439612	hsa-miR-4324	CLIP-seq
MIRT1439613	hsa-miR-4435	CLIP-seq
MIRT1439614	hsa-miR-4436b-5p	CLIP-seq
MIRT1439615	hsa-miR-4701-5p	CLIP-seq
MIRT1439616	hsa-miR-4710	CLIP-seq
MIRT1439617	hsa-miR-4721	CLIP-seq
MIRT1439618	hsa-miR-4735-5p	CLIP-seq
MIRT1439619	hsa-miR-4755-3p	CLIP-seq
MIRT1439620	hsa-miR-4766-5p	CLIP-seq
MIRT1439621	hsa-miR-544	CLIP-seq
MIRT1439622	hsa-miR-544b	CLIP-seq
MIRT1439623	hsa-miR-548a-5p	CLIP-seq
MIRT1439624	hsa-miR-548ab	CLIP-seq
MIRT1439625	hsa-miR-548ak	CLIP-seq
MIRT1439626	hsa-miR-548b-5p	CLIP-seq
MIRT1439627	hsa-miR-548c-5p	CLIP-seq
MIRT1439628	hsa-miR-548d-5p	CLIP-seq
MIRT1439629	hsa-miR-548h	CLIP-seq
MIRT1439630	hsa-miR-548i	CLIP-seq
MIRT1439631	hsa-miR-548j	CLIP-seq
MIRT1439632	hsa-miR-548s	CLIP-seq
MIRT1439633	hsa-miR-548w	CLIP-seq
MIRT1439634	hsa-miR-548y	CLIP-seq
MIRT1439635	hsa-miR-559	CLIP-seq
MIRT1439636	hsa-miR-588	CLIP-seq
MIRT2131634	hsa-miR-1827	CLIP-seq
MIRT2352961	hsa-miR-3150a-3p	CLIP-seq
MIRT2352962	hsa-miR-3175	CLIP-seq
MIRT2352963	hsa-miR-3617	CLIP-seq
MIRT2352964	hsa-miR-4667-5p	CLIP-seq
MIRT2352965	hsa-miR-4695-5p	CLIP-seq
MIRT2352966	hsa-miR-4700-5p	CLIP-seq
MIRT2352967	hsa-miR-628-5p	CLIP-seq
MIRT2352968	hsa-miR-641	CLIP-seq
MIRT2352969	hsa-miR-765	CLIP-seq
MIRT2352970	hsa-miR-939	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq
MIRT2461864	hsa-miR-4286	CLIP-seq
MIRT2461865	hsa-miR-4323	CLIP-seq
MIRT2461866	hsa-miR-4758-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005654	Component	Nucleoplasm	IBA
GO:0005654	Component	Nucleoplasm	IDA
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: 619604
• HGNC: 26579
• e!Ensembl: ENSG00000167105

Protein

• UniProt ID: Q6UXU6
• Protein name: Transmembrane protein 92
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF11669	WBP-1	32 → 141	WW domain-binding protein 1	Family

• Sequence:

  MSQAWVPGLAPTLLFSLLAGPQKIAAKCGLILACPKGFKCCGDSCCQENELFPGPVRIFV
  IIFLVILSVFCICGLAKCFCRNCREPEPDSPVDCRGPLELPSIIPPERVRVSLSAPPPPY
  SEVILKPSLGPTPTEPPPPYSFRPEEYTGDQRGIDNPAF

• Sequence length: 159

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Bilateral squint	Likely pathogenic	rs730882247	RCV000162187
Cerebellar atrophy	Likely pathogenic	rs730882247	RCV000162187
Global developmental delay	Likely pathogenic	rs730882247	RCV000162187
Hydrocephalus	Likely pathogenic	rs730882247	RCV000162187