Gene Gene information from NCBI Gene database.
Entrez ID 161291
Gene name Transmembrane protein 30B
Gene symbol TMEM30B
Synonyms (NCBI Gene)
CDC50B
Chromosome 14
Chromosome location 14q23.1
miRNA miRNA information provided by mirtarbase database.
629
miRTarBase ID miRNA Experiments Reference
MIRT018891 hsa-miR-335-5p Microarray 18185580
MIRT030135 hsa-miR-26b-5p Microarray 19088304
MIRT625099 hsa-miR-34b-3p HITS-CLIP 22927820
MIRT609232 hsa-miR-8485 HITS-CLIP 22927820
MIRT625098 hsa-miR-377-3p HITS-CLIP 22927820
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20947505, 20961850, 21914794, 32296183
GO:0005783 Component Endoplasmic reticulum IBA
GO:0005789 Component Endoplasmic reticulum membrane IDA 37293153
GO:0005794 Component Golgi apparatus IBA
GO:0005886 Component Plasma membrane IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611029 27254 ENSG00000182107
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q3MIR4
Protein name Cell cycle control protein 50B (P4-ATPase flippase complex beta subunit TMEM30B) (Transmembrane protein 30B)
Protein function Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribut
PDB 7VGH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03381 CDC50 53 345 LEM3 (ligand-effect modulator 3) family / CDC50 family Family
Sequence
Sequence length 351
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Efferocytosis  
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
EBV-positive nodal T- and NK-cell lymphoma Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MELANOMA CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Breast Neoplasms Associate 34215221
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Associate 26169495
★☆☆☆☆
Found in Text Mining only
Meningioma Associate 20685720
★☆☆☆☆
Found in Text Mining only
Peritonitis Associate 22836805
★☆☆☆☆
Found in Text Mining only