DAP (death associated protein)

Gene

• Entrez ID: 1611
• Gene name: Death associated protein
• Gene symbol: DAP
• Synonyms (NCBI Gene): DAP1
• Chromosome: 5
• Chromosome location: 5p15.2
• Summary: This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gen

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005726	hsa-miR-183-5p	qRT-PCR	20602797
MIRT018510	hsa-miR-335-5p	Microarray	18185580
MIRT923065	hsa-miR-105	CLIP-seq
MIRT923066	hsa-miR-1178	CLIP-seq
MIRT923067	hsa-miR-1207-3p	CLIP-seq
MIRT923068	hsa-miR-124	CLIP-seq
MIRT923069	hsa-miR-1248	CLIP-seq
MIRT923070	hsa-miR-1253	CLIP-seq
MIRT923071	hsa-miR-1256	CLIP-seq
MIRT923072	hsa-miR-125a-3p	CLIP-seq
MIRT923073	hsa-miR-1273g	CLIP-seq
MIRT923074	hsa-miR-1290	CLIP-seq
MIRT923075	hsa-miR-1299	CLIP-seq
MIRT923076	hsa-miR-134	CLIP-seq
MIRT923077	hsa-miR-138	CLIP-seq
MIRT923078	hsa-miR-208a	CLIP-seq
MIRT923079	hsa-miR-208b	CLIP-seq
MIRT923080	hsa-miR-216a	CLIP-seq
MIRT923081	hsa-miR-216b	CLIP-seq
MIRT923082	hsa-miR-29a	CLIP-seq
MIRT923083	hsa-miR-29b	CLIP-seq
MIRT923084	hsa-miR-29c	CLIP-seq
MIRT923085	hsa-miR-3065-3p	CLIP-seq
MIRT923086	hsa-miR-3118	CLIP-seq
MIRT923087	hsa-miR-3144-3p	CLIP-seq
MIRT923088	hsa-miR-3152-5p	CLIP-seq
MIRT923089	hsa-miR-3159	CLIP-seq
MIRT923090	hsa-miR-3167	CLIP-seq
MIRT923091	hsa-miR-323-5p	CLIP-seq
MIRT923092	hsa-miR-3545-3p	CLIP-seq
MIRT923093	hsa-miR-3614-5p	CLIP-seq
MIRT923094	hsa-miR-3658	CLIP-seq
MIRT923095	hsa-miR-3667-5p	CLIP-seq
MIRT923096	hsa-miR-3714	CLIP-seq
MIRT923097	hsa-miR-371-5p	CLIP-seq
MIRT923098	hsa-miR-371b-5p	CLIP-seq
MIRT923099	hsa-miR-383	CLIP-seq
MIRT923100	hsa-miR-3910	CLIP-seq
MIRT923101	hsa-miR-3934	CLIP-seq
MIRT923102	hsa-miR-4279	CLIP-seq
MIRT923103	hsa-miR-4297	CLIP-seq
MIRT923104	hsa-miR-4434	CLIP-seq
MIRT923105	hsa-miR-4456	CLIP-seq
MIRT923106	hsa-miR-4477b	CLIP-seq
MIRT923107	hsa-miR-4516	CLIP-seq
MIRT923108	hsa-miR-4521	CLIP-seq
MIRT923109	hsa-miR-4530	CLIP-seq
MIRT923110	hsa-miR-4531	CLIP-seq
MIRT923111	hsa-miR-4760-5p	CLIP-seq
MIRT923112	hsa-miR-4772-5p	CLIP-seq
MIRT923113	hsa-miR-4773	CLIP-seq
MIRT923114	hsa-miR-4774-3p	CLIP-seq
MIRT923115	hsa-miR-4782-5p	CLIP-seq
MIRT923116	hsa-miR-499-5p	CLIP-seq
MIRT923117	hsa-miR-506	CLIP-seq
MIRT923118	hsa-miR-513c	CLIP-seq
MIRT923119	hsa-miR-514b-5p	CLIP-seq
MIRT923120	hsa-miR-516b	CLIP-seq
MIRT923121	hsa-miR-550a	CLIP-seq
MIRT923122	hsa-miR-578	CLIP-seq
MIRT923123	hsa-miR-670	CLIP-seq
MIRT923124	hsa-miR-764	CLIP-seq
MIRT923125	hsa-miR-767-3p	CLIP-seq
MIRT923126	hsa-miR-873	CLIP-seq
MIRT923127	hsa-miR-876-3p	CLIP-seq
MIRT923128	hsa-miR-876-5p	CLIP-seq
MIRT923129	hsa-miR-885-3p	CLIP-seq
MIRT923130	hsa-miR-922	CLIP-seq
MIRT923131	hsa-miR-942	CLIP-seq
MIRT1922678	hsa-miR-151-3p	CLIP-seq
MIRT1922679	hsa-miR-3681	CLIP-seq
MIRT1973473	hsa-miR-103a	CLIP-seq
MIRT923065	hsa-miR-105	CLIP-seq
MIRT1973474	hsa-miR-107	CLIP-seq
MIRT1973475	hsa-miR-1184	CLIP-seq
MIRT923069	hsa-miR-1248	CLIP-seq
MIRT923077	hsa-miR-138	CLIP-seq
MIRT1973476	hsa-miR-150	CLIP-seq
MIRT1973477	hsa-miR-188-3p	CLIP-seq
MIRT1973478	hsa-miR-193a-5p	CLIP-seq
MIRT923080	hsa-miR-216a	CLIP-seq
MIRT923081	hsa-miR-216b	CLIP-seq
MIRT923087	hsa-miR-3144-3p	CLIP-seq
MIRT1973479	hsa-miR-3179	CLIP-seq
MIRT1973480	hsa-miR-3661	CLIP-seq
MIRT1973481	hsa-miR-3675-5p	CLIP-seq
MIRT1973482	hsa-miR-3691-3p	CLIP-seq
MIRT923097	hsa-miR-371-5p	CLIP-seq
MIRT923098	hsa-miR-371b-5p	CLIP-seq
MIRT923099	hsa-miR-383	CLIP-seq
MIRT1973483	hsa-miR-3913-3p	CLIP-seq
MIRT1973484	hsa-miR-3918	CLIP-seq
MIRT923101	hsa-miR-3934	CLIP-seq
MIRT1973485	hsa-miR-3944-5p	CLIP-seq
MIRT1973486	hsa-miR-4270	CLIP-seq
MIRT923103	hsa-miR-4297	CLIP-seq
MIRT1973487	hsa-miR-4328	CLIP-seq
MIRT1973488	hsa-miR-4441	CLIP-seq
MIRT1973489	hsa-miR-4464	CLIP-seq
MIRT1973490	hsa-miR-4469	CLIP-seq
MIRT1973491	hsa-miR-4512	CLIP-seq
MIRT1973492	hsa-miR-4633-3p	CLIP-seq
MIRT1973493	hsa-miR-4635	CLIP-seq
MIRT1973494	hsa-miR-4713-5p	CLIP-seq
MIRT1973495	hsa-miR-4748	CLIP-seq
MIRT923112	hsa-miR-4772-5p	CLIP-seq
MIRT1973496	hsa-miR-489	CLIP-seq
MIRT923118	hsa-miR-513c	CLIP-seq
MIRT923119	hsa-miR-514b-5p	CLIP-seq
MIRT1973497	hsa-miR-519a	CLIP-seq
MIRT1973498	hsa-miR-519b-3p	CLIP-seq
MIRT1973499	hsa-miR-519c-3p	CLIP-seq
MIRT1973500	hsa-miR-532-3p	CLIP-seq
MIRT1973501	hsa-miR-542-3p	CLIP-seq
MIRT923121	hsa-miR-550a	CLIP-seq
MIRT1973502	hsa-miR-550b	CLIP-seq
MIRT1973503	hsa-miR-552	CLIP-seq
MIRT923122	hsa-miR-578	CLIP-seq
MIRT1973504	hsa-miR-631	CLIP-seq
MIRT923126	hsa-miR-873	CLIP-seq
MIRT923129	hsa-miR-885-3p	CLIP-seq
MIRT923130	hsa-miR-922	CLIP-seq
MIRT923131	hsa-miR-942	CLIP-seq
MIRT923065	hsa-miR-105	CLIP-seq
MIRT2209046	hsa-miR-1197	CLIP-seq
MIRT2209047	hsa-miR-1251	CLIP-seq
MIRT2209048	hsa-miR-1271	CLIP-seq
MIRT2209049	hsa-miR-182	CLIP-seq
MIRT923087	hsa-miR-3144-3p	CLIP-seq
MIRT2209050	hsa-miR-3622b-5p	CLIP-seq
MIRT2209051	hsa-miR-3675-3p	CLIP-seq
MIRT923099	hsa-miR-383	CLIP-seq
MIRT1973483	hsa-miR-3913-3p	CLIP-seq
MIRT923101	hsa-miR-3934	CLIP-seq
MIRT2209052	hsa-miR-4305	CLIP-seq
MIRT2209053	hsa-miR-4496	CLIP-seq
MIRT2209054	hsa-miR-4514	CLIP-seq
MIRT2209055	hsa-miR-4642	CLIP-seq
MIRT2209056	hsa-miR-4645-5p	CLIP-seq
MIRT2209057	hsa-miR-4673	CLIP-seq
MIRT2209058	hsa-miR-4692	CLIP-seq
MIRT2209059	hsa-miR-4733-3p	CLIP-seq
MIRT923112	hsa-miR-4772-5p	CLIP-seq
MIRT1973496	hsa-miR-489	CLIP-seq
MIRT2209060	hsa-miR-711	CLIP-seq
MIRT923126	hsa-miR-873	CLIP-seq
MIRT2209061	hsa-miR-9	CLIP-seq
MIRT2209062	hsa-miR-96	CLIP-seq
MIRT923065	hsa-miR-105	CLIP-seq
MIRT2386709	hsa-miR-149	CLIP-seq
MIRT2386710	hsa-miR-3064-5p	CLIP-seq
MIRT2386711	hsa-miR-3689a-3p	CLIP-seq
MIRT2386712	hsa-miR-3689c	CLIP-seq
MIRT1973489	hsa-miR-4464	CLIP-seq
MIRT2386713	hsa-miR-4728-5p	CLIP-seq
MIRT2209059	hsa-miR-4733-3p	CLIP-seq
MIRT1973495	hsa-miR-4748	CLIP-seq
MIRT2386714	hsa-miR-4794	CLIP-seq
MIRT923129	hsa-miR-885-3p	CLIP-seq
MIRT2448027	hsa-miR-3184	CLIP-seq
MIRT2448028	hsa-miR-423-5p	CLIP-seq
MIRT2448029	hsa-miR-4263	CLIP-seq
MIRT2448030	hsa-miR-4426	CLIP-seq
MIRT2448031	hsa-miR-4489	CLIP-seq
MIRT2448032	hsa-miR-4647	CLIP-seq
MIRT2448033	hsa-miR-4662b	CLIP-seq
MIRT2448034	hsa-miR-576-5p	CLIP-seq
MIRT1973475	hsa-miR-1184	CLIP-seq
MIRT2209046	hsa-miR-1197	CLIP-seq
MIRT2512880	hsa-miR-1205	CLIP-seq
MIRT2512881	hsa-miR-1207-5p	CLIP-seq
MIRT2512882	hsa-miR-1226	CLIP-seq
MIRT2209047	hsa-miR-1251	CLIP-seq
MIRT923070	hsa-miR-1253	CLIP-seq
MIRT2512883	hsa-miR-1287	CLIP-seq
MIRT923074	hsa-miR-1290	CLIP-seq
MIRT923075	hsa-miR-1299	CLIP-seq
MIRT2512884	hsa-miR-1343	CLIP-seq
MIRT2512885	hsa-miR-1909	CLIP-seq
MIRT2512886	hsa-miR-3130-3p	CLIP-seq
MIRT2512887	hsa-miR-3135b	CLIP-seq
MIRT2512888	hsa-miR-3158-5p	CLIP-seq
MIRT923090	hsa-miR-3167	CLIP-seq
MIRT2512889	hsa-miR-3192	CLIP-seq
MIRT2512890	hsa-miR-324-5p	CLIP-seq
MIRT2512891	hsa-miR-3610	CLIP-seq
MIRT1973480	hsa-miR-3661	CLIP-seq
MIRT2209051	hsa-miR-3675-3p	CLIP-seq
MIRT2386711	hsa-miR-3689a-3p	CLIP-seq
MIRT2386712	hsa-miR-3689c	CLIP-seq
MIRT923096	hsa-miR-3714	CLIP-seq
MIRT2209052	hsa-miR-4305	CLIP-seq
MIRT2512892	hsa-miR-4436b-3p	CLIP-seq
MIRT2512893	hsa-miR-4468	CLIP-seq
MIRT923106	hsa-miR-4477b	CLIP-seq
MIRT2512894	hsa-miR-4479	CLIP-seq
MIRT2209053	hsa-miR-4496	CLIP-seq
MIRT2512895	hsa-miR-4504	CLIP-seq
MIRT2512896	hsa-miR-4505	CLIP-seq
MIRT2209054	hsa-miR-4514	CLIP-seq
MIRT2512897	hsa-miR-4527	CLIP-seq
MIRT2209056	hsa-miR-4645-5p	CLIP-seq
MIRT2512898	hsa-miR-4650-5p	CLIP-seq
MIRT2512899	hsa-miR-4667-3p	CLIP-seq
MIRT2209057	hsa-miR-4673	CLIP-seq
MIRT2512900	hsa-miR-4676-5p	CLIP-seq
MIRT2209058	hsa-miR-4692	CLIP-seq
MIRT2512901	hsa-miR-4694-5p	CLIP-seq
MIRT2512902	hsa-miR-4715-3p	CLIP-seq
MIRT2386713	hsa-miR-4728-5p	CLIP-seq
MIRT2209059	hsa-miR-4733-3p	CLIP-seq
MIRT2512903	hsa-miR-4763-3p	CLIP-seq
MIRT2512904	hsa-miR-4771	CLIP-seq
MIRT923115	hsa-miR-4782-5p	CLIP-seq
MIRT2512905	hsa-miR-4793-3p	CLIP-seq
MIRT2512906	hsa-miR-501-3p	CLIP-seq
MIRT2512907	hsa-miR-502-3p	CLIP-seq
MIRT923120	hsa-miR-516b	CLIP-seq
MIRT2512908	hsa-miR-544	CLIP-seq
MIRT2512909	hsa-miR-548an	CLIP-seq
MIRT2512910	hsa-miR-548c-3p	CLIP-seq
MIRT2512911	hsa-miR-575	CLIP-seq
MIRT1973504	hsa-miR-631	CLIP-seq
MIRT2209060	hsa-miR-711	CLIP-seq
MIRT923128	hsa-miR-876-5p	CLIP-seq
MIRT2512912	hsa-miR-940	CLIP-seq
MIRT1973475	hsa-miR-1184	CLIP-seq
MIRT2209046	hsa-miR-1197	CLIP-seq
MIRT2512880	hsa-miR-1205	CLIP-seq
MIRT2512881	hsa-miR-1207-5p	CLIP-seq
MIRT2512882	hsa-miR-1226	CLIP-seq
MIRT2209047	hsa-miR-1251	CLIP-seq
MIRT923070	hsa-miR-1253	CLIP-seq
MIRT2512883	hsa-miR-1287	CLIP-seq
MIRT923074	hsa-miR-1290	CLIP-seq
MIRT923075	hsa-miR-1299	CLIP-seq
MIRT2512884	hsa-miR-1343	CLIP-seq
MIRT2512885	hsa-miR-1909	CLIP-seq
MIRT2512886	hsa-miR-3130-3p	CLIP-seq
MIRT2512887	hsa-miR-3135b	CLIP-seq
MIRT2512888	hsa-miR-3158-5p	CLIP-seq
MIRT923090	hsa-miR-3167	CLIP-seq
MIRT2512889	hsa-miR-3192	CLIP-seq
MIRT2512890	hsa-miR-324-5p	CLIP-seq
MIRT2512891	hsa-miR-3610	CLIP-seq
MIRT1973480	hsa-miR-3661	CLIP-seq
MIRT2209051	hsa-miR-3675-3p	CLIP-seq
MIRT2386711	hsa-miR-3689a-3p	CLIP-seq
MIRT2386712	hsa-miR-3689c	CLIP-seq
MIRT923096	hsa-miR-3714	CLIP-seq
MIRT2209052	hsa-miR-4305	CLIP-seq
MIRT2512892	hsa-miR-4436b-3p	CLIP-seq
MIRT2512893	hsa-miR-4468	CLIP-seq
MIRT923106	hsa-miR-4477b	CLIP-seq
MIRT2512894	hsa-miR-4479	CLIP-seq
MIRT2209053	hsa-miR-4496	CLIP-seq
MIRT2512895	hsa-miR-4504	CLIP-seq
MIRT2512896	hsa-miR-4505	CLIP-seq
MIRT2209054	hsa-miR-4514	CLIP-seq
MIRT2512897	hsa-miR-4527	CLIP-seq
MIRT2209056	hsa-miR-4645-5p	CLIP-seq
MIRT2512898	hsa-miR-4650-5p	CLIP-seq
MIRT2512899	hsa-miR-4667-3p	CLIP-seq
MIRT2209057	hsa-miR-4673	CLIP-seq
MIRT2512900	hsa-miR-4676-5p	CLIP-seq
MIRT2209058	hsa-miR-4692	CLIP-seq
MIRT2512901	hsa-miR-4694-5p	CLIP-seq
MIRT2512902	hsa-miR-4715-3p	CLIP-seq
MIRT2386713	hsa-miR-4728-5p	CLIP-seq
MIRT2209059	hsa-miR-4733-3p	CLIP-seq
MIRT2512903	hsa-miR-4763-3p	CLIP-seq
MIRT2512904	hsa-miR-4771	CLIP-seq
MIRT923115	hsa-miR-4782-5p	CLIP-seq
MIRT2512905	hsa-miR-4793-3p	CLIP-seq
MIRT2512906	hsa-miR-501-3p	CLIP-seq
MIRT2512907	hsa-miR-502-3p	CLIP-seq
MIRT923120	hsa-miR-516b	CLIP-seq
MIRT2512908	hsa-miR-544	CLIP-seq
MIRT2512909	hsa-miR-548an	CLIP-seq
MIRT2512910	hsa-miR-548c-3p	CLIP-seq
MIRT2512911	hsa-miR-575	CLIP-seq
MIRT1973504	hsa-miR-631	CLIP-seq
MIRT2209060	hsa-miR-711	CLIP-seq
MIRT923128	hsa-miR-876-5p	CLIP-seq
MIRT2512912	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0006417	Process	Regulation of translation	IEA
GO:0006914	Process	Autophagy	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	IGI	7828849
GO:0010507	Process	Negative regulation of autophagy	IBA
GO:0010507	Process	Negative regulation of autophagy	IMP	20537536
GO:0043022	Function	Ribosome binding	IBA
GO:0097190	Process	Apoptotic signaling pathway	IBA
GO:0097190	Process	Apoptotic signaling pathway	IMP	7828849
GO:0141014	Process	Ribosome hibernation	IBA

Other IDs

• MIM: 600954
• HGNC: 2672
• e!Ensembl: ENSG00000112977

Protein

• UniProt ID: P51397
• Protein name: Death-associated protein 1 (DAP-1)
• Protein function: Ribosome-binding protein involved in ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). Acts via its association with eiF5a (EIF5A and EIF5A2) at
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15228	DAP	12 → 102	Death-associated protein	Family

• Sequence:

  MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPSPPKPTVFIS
  GVIARGDKDFPPAAAQVAHQKPHASMDKHPSPRTQHIQQPRK

• Sequence length: 102