Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	161003
Gene name	Stomatin like 3
Gene symbol	STOML3
Synonyms (NCBI Gene)	Epb7.2lSRO
Chromosome	13
Chromosome location	13q13.3

102

Show/Hide all (102)

miRTarBase ID	miRNA	Experiments	Reference
MIRT454797	hsa-miR-4491	PAR-CLIP	23592263
MIRT454796	hsa-miR-4657	PAR-CLIP	23592263
MIRT454795	hsa-miR-3665	PAR-CLIP	23592263
MIRT454794	hsa-miR-4764-5p	PAR-CLIP	23592263
MIRT454793	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT454792	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT454791	hsa-miR-4736	PAR-CLIP	23592263
MIRT454790	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT454789	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT454788	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT454787	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT454786	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT454785	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT454784	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT454783	hsa-miR-5698	PAR-CLIP	23592263
MIRT454782	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT454781	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT454780	hsa-miR-4525	PAR-CLIP	23592263
MIRT454779	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT454778	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT454777	hsa-miR-376b-5p	PAR-CLIP	23592263
MIRT454776	hsa-miR-376c-5p	PAR-CLIP	23592263
MIRT454774	hsa-miR-3691-5p	PAR-CLIP	23592263
MIRT454775	hsa-miR-8056	PAR-CLIP	23592263
MIRT454773	hsa-miR-4447	PAR-CLIP	23592263
MIRT454772	hsa-miR-4472	PAR-CLIP	23592263
MIRT454771	hsa-miR-7150	PAR-CLIP	23592263
MIRT454770	hsa-miR-1275	PAR-CLIP	23592263
MIRT454769	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT454768	hsa-miR-4752	PAR-CLIP	23592263
MIRT454767	hsa-miR-182-5p	PAR-CLIP	23592263
MIRT454766	hsa-miR-1271-5p	PAR-CLIP	23592263
MIRT454765	hsa-miR-96-5p	PAR-CLIP	23592263
MIRT454797	hsa-miR-4491	PAR-CLIP	23592263
MIRT454796	hsa-miR-4657	PAR-CLIP	23592263
MIRT454795	hsa-miR-3665	PAR-CLIP	23592263
MIRT454794	hsa-miR-4764-5p	PAR-CLIP	23592263
MIRT454793	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT454792	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT454791	hsa-miR-4736	PAR-CLIP	23592263
MIRT454790	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT454789	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT454788	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT454787	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT454786	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT454785	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT454784	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT454783	hsa-miR-5698	PAR-CLIP	23592263
MIRT454782	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT454781	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT454780	hsa-miR-4525	PAR-CLIP	23592263
MIRT454779	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT454778	hsa-miR-92a-2-5p	PAR-CLIP	23592263
MIRT454777	hsa-miR-376b-5p	PAR-CLIP	23592263
MIRT454776	hsa-miR-376c-5p	PAR-CLIP	23592263
MIRT454774	hsa-miR-3691-5p	PAR-CLIP	23592263
MIRT454775	hsa-miR-8056	PAR-CLIP	23592263
MIRT454773	hsa-miR-4447	PAR-CLIP	23592263
MIRT454772	hsa-miR-4472	PAR-CLIP	23592263
MIRT454771	hsa-miR-7150	PAR-CLIP	23592263
MIRT454770	hsa-miR-1275	PAR-CLIP	23592263
MIRT454769	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT454768	hsa-miR-4752	PAR-CLIP	23592263
MIRT454767	hsa-miR-182-5p	PAR-CLIP	23592263
MIRT454766	hsa-miR-1271-5p	PAR-CLIP	23592263
MIRT454765	hsa-miR-96-5p	PAR-CLIP	23592263
MIRT1399015	hsa-miR-452	CLIP-seq
MIRT1399016	hsa-miR-4653-3p	CLIP-seq
MIRT1399017	hsa-miR-4666-5p	CLIP-seq
MIRT1399018	hsa-miR-4676-3p	CLIP-seq
MIRT1399019	hsa-miR-4693-5p	CLIP-seq
MIRT1399020	hsa-miR-4802-5p	CLIP-seq
MIRT1399021	hsa-miR-1269	CLIP-seq
MIRT1399022	hsa-miR-1269b	CLIP-seq
MIRT1399023	hsa-miR-1288	CLIP-seq
MIRT1399024	hsa-miR-3661	CLIP-seq
MIRT1399025	hsa-miR-3670	CLIP-seq
MIRT1399026	hsa-miR-3690	CLIP-seq
MIRT1399027	hsa-miR-378	CLIP-seq
MIRT1399028	hsa-miR-378b	CLIP-seq
MIRT1399029	hsa-miR-378c	CLIP-seq
MIRT1399030	hsa-miR-378d	CLIP-seq
MIRT1399031	hsa-miR-378e	CLIP-seq
MIRT1399032	hsa-miR-378f	CLIP-seq
MIRT1399033	hsa-miR-378h	CLIP-seq
MIRT1399034	hsa-miR-378i	CLIP-seq
MIRT1399035	hsa-miR-422a	CLIP-seq
MIRT1399036	hsa-miR-4515	CLIP-seq
MIRT1399037	hsa-miR-4677-3p	CLIP-seq
MIRT1399038	hsa-miR-4740-5p	CLIP-seq
MIRT1399039	hsa-miR-619	CLIP-seq
MIRT1399040	hsa-miR-631	CLIP-seq
MIRT1399041	hsa-miR-769-5p	CLIP-seq
MIRT1399015	hsa-miR-452	CLIP-seq
MIRT1399016	hsa-miR-4653-3p	CLIP-seq
MIRT1399017	hsa-miR-4666-5p	CLIP-seq
MIRT1399018	hsa-miR-4676-3p	CLIP-seq
MIRT1399019	hsa-miR-4693-5p	CLIP-seq
MIRT1399020	hsa-miR-4802-5p	CLIP-seq
MIRT2460703	hsa-miR-625	CLIP-seq
MIRT2460703	hsa-miR-625	CLIP-seq
MIRT2460703	hsa-miR-625	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005929	Component	Cilium	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0008200	Function	Ion channel inhibitor activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045121	Component	Membrane raft	IEA

MIM	HGNC	e!Ensembl
608327	19420	ENSG00000133115

Q8TAV4

Protein name

Stomatin-like protein 3 (SLP-3)

Protein function

Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations. {ECO:0000

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	52 → 225	SPFH domain / Band 7 family	Family

Sequence

MDSRVSSPEKQDKENFVGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERA
VVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVY
YRIYSAVSAVANVNDVHQATFLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDATE
LWGIRVARVEIKDVRIPVQLQRSMAAEAEATREARAKVLAAEGEMNASKSLKSASMVLAE
SPIALQLRYLQTLSTVATEKNSTIVFPLPMNILEGIGGVSYDNHKKLPNKA

Sequence length

291

Interactions

View interactions

	Reactome
			Stimuli-sensing channels

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Asthma	Associate	36835202	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prader Willi Syndrome	Associate	12411498	★★★★★ ★☆☆☆☆ Found in Text Mining only

STOML3 (stomatin like 3)