CCDC60 (coiled-coil domain containing 60)

Gene

• Entrez ID: 160777
• Gene name: Coiled-coil domain containing 60
• Gene symbol: CCDC60
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12q24.23

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT869356	hsa-miR-193a-5p	CLIP-seq
MIRT869357	hsa-miR-3184	CLIP-seq
MIRT869358	hsa-miR-3190	CLIP-seq
MIRT869359	hsa-miR-342-5p	CLIP-seq
MIRT869360	hsa-miR-3911	CLIP-seq
MIRT869361	hsa-miR-423-5p	CLIP-seq
MIRT869362	hsa-miR-4455	CLIP-seq
MIRT869363	hsa-miR-4651	CLIP-seq
MIRT869364	hsa-miR-4664-5p	CLIP-seq
MIRT869365	hsa-miR-4667-5p	CLIP-seq
MIRT869366	hsa-miR-4700-5p	CLIP-seq
MIRT869367	hsa-miR-608	CLIP-seq
MIRT869368	hsa-miR-637	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 31515488

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IWA6
• Protein name: Coiled-coil domain-containing protein 60
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15769	DUF4698	59 → 540	Domain of unknown function (DUF4698)	Family

• Sequence:

  MTKVPATKKLQSSPNSGAVRPFYASENLRQVPDKPMKSIKYMDKEIINLKKDLIRSRFLI
  QSVKIGRGYFAILREETAKKKKQQQLQKLKEEERNKFQPAEKISEIHYGDTLLSTYDDEK
  LKTLGARVTRRPFTPIHSCIISPSLTEAHVEPLFRQLCALHWLLEALTIDHTHHTMKPVI
  TCWNPKDPGGSKSTIKKINKDKSMGQKWEHFITAPKTKKFKIPTMRVTNRKPSRRGSTLS
  LSRASGGSSPQSSMISVNPGSDEPPSVNTQVTSSKDIEDNESSSTKPDEEPLYMNLQKLL
  EMVREDARRTVTIENGMQRKAPSILSVLKQNKSNSAYKEMQTTLKSSERSSSTSAESHIQ
  PVQKKSKNRTNCDINIHYKSGVCNTMRAKFYSVAQEAGFCLQDKMEILMKRQEERGIQKF
  RAFVLVSNFQKDIAKMRHHISVVKGDAEEIADHWYFDLLSKLPEDLKNFRPAKKILVKLQ
  KFGENLDLRIRPHVLLKVLQDLRIWELCSPDIAVAIEFVREHIIHMPQEDYISWLQSRIN
  IPIGPYSALR

• Sequence length: 550

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BIPOLAR DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Infertility Male	Associate	34604380	★☆☆☆☆ Found in Text Mining only