CLECL1 (C-type lectin like 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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160365 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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C-type lectin like 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CLECL1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CLECL1P, DCAL-1, DCAL1 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.31 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a type II transmembrane, C-type lectin-like protein that is highly expressed on dendritic and B cells. This protein may act as a T-cell costimulatory molecule that enhances interleukin-4 production, and maybe involved in the regulation o |
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||
UniProt ID | Q8IZS7 | |
Protein name | Putative C-type lectin-like domain family 1 (C-type lectin-like domain family 1 pseudogene) (Dendritic cell-associated lectin 1) (DC-associated lectin-1) (DCAL-1) | |
Protein function | May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immun | |
Family and domains | ||
Tissue specificity | TISSUE SPECIFICITY: Expressed in spleen, lymph node, and tonsil. Lower expression in peripheral blood, bone marrow, and colon. No expression detected in thymus. Highly expressed in dendritic and B-cells. {ECO:0000269|PubMed:12421943}. | |
Sequence |
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Sequence length | 167 | |
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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