Gene Gene information from NCBI Gene database.
Entrez ID 159963
Gene name Solute carrier family 5 member 12
Gene symbol SLC5A12
Synonyms (NCBI Gene)
SMCT2
Chromosome 11
Chromosome location 11p14.2
Summary Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the h
miRNA miRNA information provided by mirtarbase database.
280
miRTarBase ID miRNA Experiments Reference
MIRT721584 hsa-miR-6890-3p HITS-CLIP 19536157
MIRT721583 hsa-miR-205-5p HITS-CLIP 19536157
MIRT721582 hsa-miR-4268 HITS-CLIP 19536157
MIRT721581 hsa-miR-4448 HITS-CLIP 19536157
MIRT721580 hsa-miR-505-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25
GO ID Ontology Definition Evidence Reference
GO:0005343 Function Organic acid:sodium symporter activity TAS
GO:0005654 Component Nucleoplasm IDA
GO:0005886 Component Plasma membrane IDA
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612455 28750 ENSG00000148942
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q1EHB4
Protein name Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12)
Protein function Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter (PubMed:17692818). Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionat
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00474 SSF 41 445 Sodium:solute symporter family Family
Sequence
Sequence length 618
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Multifunctional anion exchangers