SLC5A12 (solute carrier family 5 member 12)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
159963 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Solute carrier family 5 member 12 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
SLC5A12 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
SMCT2 |
|
Chromosome
Chromosome number
|
11 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
11p14.2 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the h |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||
| UniProt ID | Q1EHB4 | ||||||||||
| Protein name | Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12) | ||||||||||
| Protein function | Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter (PubMed:17692818). Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionat | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Sequence |
|
||||||||||
| Sequence length | 618 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
|||||||
|
Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
|
||||||||||||||||
|
||||||||||||||||
|
||||||||||||||||