CYP51A1 (cytochrome P450 family 51 subfamily A member 1)

Gene

• Entrez ID: 1595
• Gene name: Cytochrome P450 family 51 subfamily A member 1
• Gene symbol: CYP51A1
• Synonyms (NCBI Gene): CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
• Chromosome: 7
• Chromosome location: 7q21.2
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic r

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT001555	hsa-miR-155-5p	pSILAC	18668040
MIRT018801	hsa-miR-335-5p	Microarray	18185580
MIRT001555	hsa-miR-155-5p	Proteomics;Other	18668040
MIRT025395	hsa-miR-34a-5p	Proteomics	21566225
MIRT025395	hsa-miR-34a-5p	Proteomics	21566225
MIRT046448	hsa-miR-15b-5p	CLASH	23622248
MIRT675930	hsa-miR-4753-5p	HITS-CLIP	23824327
MIRT675929	hsa-miR-9500	HITS-CLIP	23824327
MIRT675928	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675927	hsa-miR-764	HITS-CLIP	23824327
MIRT675926	hsa-miR-4493	HITS-CLIP	23824327
MIRT675925	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT675924	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675923	hsa-miR-4746-3p	HITS-CLIP	23824327
MIRT675922	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675921	hsa-miR-4284	HITS-CLIP	23824327
MIRT675920	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675919	hsa-miR-4747-5p	HITS-CLIP	23824327
MIRT675918	hsa-miR-5196-5p	HITS-CLIP	23824327
MIRT675917	hsa-miR-4466	HITS-CLIP	23824327
MIRT675916	hsa-miR-675-5p	HITS-CLIP	23824327
MIRT675915	hsa-miR-7977	HITS-CLIP	23824327
MIRT675914	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT462870	hsa-miR-302f	PAR-CLIP	23592263
MIRT462869	hsa-miR-3123	PAR-CLIP	23592263
MIRT462868	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT462867	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT462866	hsa-miR-3919	PAR-CLIP	23592263
MIRT462865	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT462864	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT462863	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT462862	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT462861	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT462860	hsa-miR-1827	PAR-CLIP	23592263
MIRT462859	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462858	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT462857	hsa-miR-3612	PAR-CLIP	23592263
MIRT462856	hsa-miR-650	PAR-CLIP	23592263
MIRT462855	hsa-miR-1273e	PAR-CLIP	23592263
MIRT675928	hsa-miR-383-3p	PAR-CLIP	27292025
MIRT675930	hsa-miR-4753-5p	HITS-CLIP	23824327
MIRT675929	hsa-miR-9500	HITS-CLIP	23824327
MIRT675928	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT675927	hsa-miR-764	HITS-CLIP	23824327
MIRT675926	hsa-miR-4493	HITS-CLIP	23824327
MIRT675925	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT675924	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT675923	hsa-miR-4746-3p	HITS-CLIP	23824327
MIRT675922	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT675921	hsa-miR-4284	HITS-CLIP	23824327
MIRT675920	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675919	hsa-miR-4747-5p	HITS-CLIP	23824327
MIRT675918	hsa-miR-5196-5p	HITS-CLIP	23824327
MIRT675917	hsa-miR-4466	HITS-CLIP	23824327
MIRT675916	hsa-miR-675-5p	HITS-CLIP	23824327
MIRT675915	hsa-miR-7977	HITS-CLIP	23824327
MIRT675914	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT462870	hsa-miR-302f	PAR-CLIP	23592263
MIRT462869	hsa-miR-3123	PAR-CLIP	23592263
MIRT462868	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT462867	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT462866	hsa-miR-3919	PAR-CLIP	23592263
MIRT462865	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT462864	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT462863	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT462862	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT462861	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT462860	hsa-miR-1827	PAR-CLIP	23592263
MIRT462859	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462858	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT462857	hsa-miR-3612	PAR-CLIP	23592263
MIRT462856	hsa-miR-650	PAR-CLIP	23592263
MIRT462855	hsa-miR-1273e	PAR-CLIP	23592263
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT921799	hsa-miR-1285	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT921801	hsa-miR-136	CLIP-seq
MIRT921802	hsa-miR-150	CLIP-seq
MIRT921803	hsa-miR-2052	CLIP-seq
MIRT921804	hsa-miR-23a	CLIP-seq
MIRT921805	hsa-miR-23b	CLIP-seq
MIRT921806	hsa-miR-23c	CLIP-seq
MIRT921807	hsa-miR-24	CLIP-seq
MIRT921808	hsa-miR-3167	CLIP-seq
MIRT921809	hsa-miR-3187-5p	CLIP-seq
MIRT921810	hsa-miR-323-3p	CLIP-seq
MIRT921811	hsa-miR-337-3p	CLIP-seq
MIRT921812	hsa-miR-342-3p	CLIP-seq
MIRT921813	hsa-miR-3606	CLIP-seq
MIRT921814	hsa-miR-3613-3p	CLIP-seq
MIRT921815	hsa-miR-3671	CLIP-seq
MIRT921816	hsa-miR-3685	CLIP-seq
MIRT921817	hsa-miR-3690	CLIP-seq
MIRT921818	hsa-miR-369-3p	CLIP-seq
MIRT921819	hsa-miR-371-5p	CLIP-seq
MIRT921820	hsa-miR-371b-5p	CLIP-seq
MIRT921821	hsa-miR-374a	CLIP-seq
MIRT921822	hsa-miR-374b	CLIP-seq
MIRT921823	hsa-miR-384	CLIP-seq
MIRT921824	hsa-miR-3914	CLIP-seq
MIRT921825	hsa-miR-3942-3p	CLIP-seq
MIRT921826	hsa-miR-4254	CLIP-seq
MIRT921827	hsa-miR-4282	CLIP-seq
MIRT921828	hsa-miR-4303	CLIP-seq
MIRT921829	hsa-miR-4420	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT921832	hsa-miR-4662a-5p	CLIP-seq
MIRT921833	hsa-miR-4680-5p	CLIP-seq
MIRT921834	hsa-miR-4682	CLIP-seq
MIRT921835	hsa-miR-4695-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT921837	hsa-miR-4762-3p	CLIP-seq
MIRT921838	hsa-miR-4775	CLIP-seq
MIRT921839	hsa-miR-4793-3p	CLIP-seq
MIRT921840	hsa-miR-487a	CLIP-seq
MIRT921841	hsa-miR-496	CLIP-seq
MIRT921842	hsa-miR-508-5p	CLIP-seq
MIRT921843	hsa-miR-532-5p	CLIP-seq
MIRT921844	hsa-miR-548aa	CLIP-seq
MIRT921845	hsa-miR-556-3p	CLIP-seq
MIRT921846	hsa-miR-582-5p	CLIP-seq
MIRT921847	hsa-miR-600	CLIP-seq
MIRT921848	hsa-miR-612	CLIP-seq
MIRT921849	hsa-miR-651	CLIP-seq
MIRT921850	hsa-miR-661	CLIP-seq
MIRT921851	hsa-miR-766	CLIP-seq
MIRT921852	hsa-miR-876-5p	CLIP-seq
MIRT921853	hsa-miR-889	CLIP-seq
MIRT921854	hsa-miR-1200	CLIP-seq
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT921855	hsa-miR-1271	CLIP-seq
MIRT921856	hsa-miR-1295	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT921802	hsa-miR-150	CLIP-seq
MIRT921857	hsa-miR-182	CLIP-seq
MIRT921803	hsa-miR-2052	CLIP-seq
MIRT921858	hsa-miR-218	CLIP-seq
MIRT921859	hsa-miR-3119	CLIP-seq
MIRT921860	hsa-miR-3140-5p	CLIP-seq
MIRT921861	hsa-miR-3143	CLIP-seq
MIRT921862	hsa-miR-3157-5p	CLIP-seq
MIRT921863	hsa-miR-329	CLIP-seq
MIRT921864	hsa-miR-34b	CLIP-seq
MIRT921813	hsa-miR-3606	CLIP-seq
MIRT921865	hsa-miR-362-3p	CLIP-seq
MIRT921866	hsa-miR-382	CLIP-seq
MIRT921867	hsa-miR-3941	CLIP-seq
MIRT921868	hsa-miR-4275	CLIP-seq
MIRT921869	hsa-miR-4297	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT921870	hsa-miR-4536	CLIP-seq
MIRT921871	hsa-miR-4642	CLIP-seq
MIRT921872	hsa-miR-466	CLIP-seq
MIRT921873	hsa-miR-4668-3p	CLIP-seq
MIRT921874	hsa-miR-4672	CLIP-seq
MIRT921875	hsa-miR-4691-3p	CLIP-seq
MIRT921876	hsa-miR-4727-5p	CLIP-seq
MIRT921877	hsa-miR-4747-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT921878	hsa-miR-4766-5p	CLIP-seq
MIRT921879	hsa-miR-4769-3p	CLIP-seq
MIRT921880	hsa-miR-4795-3p	CLIP-seq
MIRT921840	hsa-miR-487a	CLIP-seq
MIRT921881	hsa-miR-495	CLIP-seq
MIRT921882	hsa-miR-502-5p	CLIP-seq
MIRT921883	hsa-miR-513b	CLIP-seq
MIRT921843	hsa-miR-532-5p	CLIP-seq
MIRT921884	hsa-miR-548g	CLIP-seq
MIRT921845	hsa-miR-556-3p	CLIP-seq
MIRT921885	hsa-miR-568	CLIP-seq
MIRT921886	hsa-miR-570	CLIP-seq
MIRT921846	hsa-miR-582-5p	CLIP-seq
MIRT921887	hsa-miR-590-3p	CLIP-seq
MIRT921847	hsa-miR-600	CLIP-seq
MIRT921888	hsa-miR-603	CLIP-seq
MIRT921889	hsa-miR-627	CLIP-seq
MIRT921890	hsa-miR-636	CLIP-seq
MIRT921891	hsa-miR-656	CLIP-seq
MIRT921892	hsa-miR-892b	CLIP-seq
MIRT921893	hsa-miR-924	CLIP-seq
MIRT921894	hsa-miR-935	CLIP-seq
MIRT921895	hsa-miR-96	CLIP-seq
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT1973054	hsa-miR-1269	CLIP-seq
MIRT1973055	hsa-miR-1269b	CLIP-seq
MIRT921799	hsa-miR-1285	CLIP-seq
MIRT921856	hsa-miR-1295	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT1973056	hsa-miR-1299	CLIP-seq
MIRT921801	hsa-miR-136	CLIP-seq
MIRT1973057	hsa-miR-197	CLIP-seq
MIRT921803	hsa-miR-2052	CLIP-seq
MIRT921858	hsa-miR-218	CLIP-seq
MIRT1973058	hsa-miR-3065-5p	CLIP-seq
MIRT1973059	hsa-miR-3126-3p	CLIP-seq
MIRT921808	hsa-miR-3167	CLIP-seq
MIRT921809	hsa-miR-3187-5p	CLIP-seq
MIRT921811	hsa-miR-337-3p	CLIP-seq
MIRT921864	hsa-miR-34b	CLIP-seq
MIRT921816	hsa-miR-3685	CLIP-seq
MIRT1973060	hsa-miR-3692	CLIP-seq
MIRT921818	hsa-miR-369-3p	CLIP-seq
MIRT921819	hsa-miR-371-5p	CLIP-seq
MIRT921820	hsa-miR-371b-5p	CLIP-seq
MIRT921821	hsa-miR-374a	CLIP-seq
MIRT921822	hsa-miR-374b	CLIP-seq
MIRT1973061	hsa-miR-377	CLIP-seq
MIRT921866	hsa-miR-382	CLIP-seq
MIRT921823	hsa-miR-384	CLIP-seq
MIRT921827	hsa-miR-4282	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT1973062	hsa-miR-4501	CLIP-seq
MIRT1973063	hsa-miR-4520b-3p	CLIP-seq
MIRT1973064	hsa-miR-4529-3p	CLIP-seq
MIRT921877	hsa-miR-4747-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT921882	hsa-miR-502-5p	CLIP-seq
MIRT921842	hsa-miR-508-5p	CLIP-seq
MIRT1973065	hsa-miR-5096	CLIP-seq
MIRT921843	hsa-miR-532-5p	CLIP-seq
MIRT921846	hsa-miR-582-5p	CLIP-seq
MIRT921847	hsa-miR-600	CLIP-seq
MIRT921848	hsa-miR-612	CLIP-seq
MIRT1973066	hsa-miR-617	CLIP-seq
MIRT921890	hsa-miR-636	CLIP-seq
MIRT921850	hsa-miR-661	CLIP-seq
MIRT921851	hsa-miR-766	CLIP-seq
MIRT1973067	hsa-miR-875-3p	CLIP-seq
MIRT921852	hsa-miR-876-5p	CLIP-seq
MIRT921853	hsa-miR-889	CLIP-seq
MIRT2208739	hsa-miR-1179	CLIP-seq
MIRT921854	hsa-miR-1200	CLIP-seq
MIRT2208740	hsa-miR-1207-5p	CLIP-seq
MIRT1973054	hsa-miR-1269	CLIP-seq
MIRT1973055	hsa-miR-1269b	CLIP-seq
MIRT921799	hsa-miR-1285	CLIP-seq
MIRT1973057	hsa-miR-197	CLIP-seq
MIRT921807	hsa-miR-24	CLIP-seq
MIRT2208741	hsa-miR-2964a-3p	CLIP-seq
MIRT921860	hsa-miR-3140-5p	CLIP-seq
MIRT921809	hsa-miR-3187-5p	CLIP-seq
MIRT921810	hsa-miR-323-3p	CLIP-seq
MIRT921864	hsa-miR-34b	CLIP-seq
MIRT2208742	hsa-miR-3665	CLIP-seq
MIRT1973060	hsa-miR-3692	CLIP-seq
MIRT921866	hsa-miR-382	CLIP-seq
MIRT2208743	hsa-miR-3929	CLIP-seq
MIRT2208744	hsa-miR-4274	CLIP-seq
MIRT921828	hsa-miR-4303	CLIP-seq
MIRT2208745	hsa-miR-4419b	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT2208746	hsa-miR-4468	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT2208747	hsa-miR-4478	CLIP-seq
MIRT1973063	hsa-miR-4520b-3p	CLIP-seq
MIRT1973064	hsa-miR-4529-3p	CLIP-seq
MIRT921832	hsa-miR-4662a-5p	CLIP-seq
MIRT921834	hsa-miR-4682	CLIP-seq
MIRT2208748	hsa-miR-4733-5p	CLIP-seq
MIRT2208749	hsa-miR-4736	CLIP-seq
MIRT2208750	hsa-miR-4763-3p	CLIP-seq
MIRT921878	hsa-miR-4766-5p	CLIP-seq
MIRT921838	hsa-miR-4775	CLIP-seq
MIRT921839	hsa-miR-4793-3p	CLIP-seq
MIRT2208751	hsa-miR-485-5p	CLIP-seq
MIRT921840	hsa-miR-487a	CLIP-seq
MIRT921841	hsa-miR-496	CLIP-seq
MIRT921842	hsa-miR-508-5p	CLIP-seq
MIRT1973065	hsa-miR-5096	CLIP-seq
MIRT2208752	hsa-miR-550a	CLIP-seq
MIRT921885	hsa-miR-568	CLIP-seq
MIRT921846	hsa-miR-582-5p	CLIP-seq
MIRT921847	hsa-miR-600	CLIP-seq
MIRT921848	hsa-miR-612	CLIP-seq
MIRT1973066	hsa-miR-617	CLIP-seq
MIRT921850	hsa-miR-661	CLIP-seq
MIRT921851	hsa-miR-766	CLIP-seq
MIRT2208753	hsa-miR-890	CLIP-seq
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT1973060	hsa-miR-3692	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT921843	hsa-miR-532-5p	CLIP-seq
MIRT921846	hsa-miR-582-5p	CLIP-seq
MIRT921847	hsa-miR-600	CLIP-seq
MIRT921814	hsa-miR-3613-3p	CLIP-seq
MIRT2447931	hsa-miR-3622b-5p	CLIP-seq
MIRT921819	hsa-miR-371-5p	CLIP-seq
MIRT921820	hsa-miR-371b-5p	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT2447932	hsa-miR-4645-5p	CLIP-seq
MIRT921832	hsa-miR-4662a-5p	CLIP-seq
MIRT2447933	hsa-miR-4673	CLIP-seq
MIRT2447934	hsa-miR-4676-5p	CLIP-seq
MIRT2447935	hsa-miR-4684-5p	CLIP-seq
MIRT2447936	hsa-miR-4755-3p	CLIP-seq
MIRT2447937	hsa-miR-548c-3p	CLIP-seq
MIRT2447938	hsa-miR-575	CLIP-seq
MIRT2512544	hsa-miR-10a	CLIP-seq
MIRT2512545	hsa-miR-10b	CLIP-seq
MIRT2208739	hsa-miR-1179	CLIP-seq
MIRT2208740	hsa-miR-1207-5p	CLIP-seq
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT921855	hsa-miR-1271	CLIP-seq
MIRT2512546	hsa-miR-1273g	CLIP-seq
MIRT921799	hsa-miR-1285	CLIP-seq
MIRT2512547	hsa-miR-1286	CLIP-seq
MIRT2512548	hsa-miR-1290	CLIP-seq
MIRT921856	hsa-miR-1295	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT921802	hsa-miR-150	CLIP-seq
MIRT921857	hsa-miR-182	CLIP-seq
MIRT2512549	hsa-miR-1911	CLIP-seq
MIRT921803	hsa-miR-2052	CLIP-seq
MIRT2512550	hsa-miR-2053	CLIP-seq
MIRT921858	hsa-miR-218	CLIP-seq
MIRT921804	hsa-miR-23a	CLIP-seq
MIRT921805	hsa-miR-23b	CLIP-seq
MIRT921806	hsa-miR-23c	CLIP-seq
MIRT921807	hsa-miR-24	CLIP-seq
MIRT2512551	hsa-miR-28-3p	CLIP-seq
MIRT2208741	hsa-miR-2964a-3p	CLIP-seq
MIRT2512552	hsa-miR-31	CLIP-seq
MIRT2512553	hsa-miR-3125	CLIP-seq
MIRT2512554	hsa-miR-3144-3p	CLIP-seq
MIRT921862	hsa-miR-3157-5p	CLIP-seq
MIRT2512555	hsa-miR-3160-3p	CLIP-seq
MIRT921809	hsa-miR-3187-5p	CLIP-seq
MIRT2512556	hsa-miR-3200-3p	CLIP-seq
MIRT921810	hsa-miR-323-3p	CLIP-seq
MIRT921863	hsa-miR-329	CLIP-seq
MIRT2512557	hsa-miR-335	CLIP-seq
MIRT921812	hsa-miR-342-3p	CLIP-seq
MIRT921813	hsa-miR-3606	CLIP-seq
MIRT921814	hsa-miR-3613-3p	CLIP-seq
MIRT2512558	hsa-miR-361-5p	CLIP-seq
MIRT2447931	hsa-miR-3622b-5p	CLIP-seq
MIRT921865	hsa-miR-362-3p	CLIP-seq
MIRT2208742	hsa-miR-3665	CLIP-seq
MIRT2512559	hsa-miR-3674	CLIP-seq
MIRT2512560	hsa-miR-3691-3p	CLIP-seq
MIRT1973060	hsa-miR-3692	CLIP-seq
MIRT921819	hsa-miR-371-5p	CLIP-seq
MIRT921820	hsa-miR-371b-5p	CLIP-seq
MIRT1973061	hsa-miR-377	CLIP-seq
MIRT2512561	hsa-miR-380	CLIP-seq
MIRT921866	hsa-miR-382	CLIP-seq
MIRT921824	hsa-miR-3914	CLIP-seq
MIRT2512562	hsa-miR-3916	CLIP-seq
MIRT2208743	hsa-miR-3929	CLIP-seq
MIRT921867	hsa-miR-3941	CLIP-seq
MIRT921825	hsa-miR-3942-3p	CLIP-seq
MIRT2208744	hsa-miR-4274	CLIP-seq
MIRT2512563	hsa-miR-4318	CLIP-seq
MIRT2512564	hsa-miR-4320	CLIP-seq
MIRT2208745	hsa-miR-4419b	CLIP-seq
MIRT921829	hsa-miR-4420	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT2208746	hsa-miR-4468	CLIP-seq
MIRT921831	hsa-miR-4474-3p	CLIP-seq
MIRT2208747	hsa-miR-4478	CLIP-seq
MIRT2512565	hsa-miR-4487	CLIP-seq
MIRT2512566	hsa-miR-4495	CLIP-seq
MIRT1973062	hsa-miR-4501	CLIP-seq
MIRT2512567	hsa-miR-4517	CLIP-seq
MIRT2512568	hsa-miR-452	CLIP-seq
MIRT1973063	hsa-miR-4520b-3p	CLIP-seq
MIRT2512569	hsa-miR-4521	CLIP-seq
MIRT1973064	hsa-miR-4529-3p	CLIP-seq
MIRT921870	hsa-miR-4536	CLIP-seq
MIRT2512570	hsa-miR-4539	CLIP-seq
MIRT921871	hsa-miR-4642	CLIP-seq
MIRT2447932	hsa-miR-4645-5p	CLIP-seq
MIRT921872	hsa-miR-466	CLIP-seq
MIRT921832	hsa-miR-4662a-5p	CLIP-seq
MIRT921874	hsa-miR-4672	CLIP-seq
MIRT2447933	hsa-miR-4673	CLIP-seq
MIRT2512571	hsa-miR-4676-3p	CLIP-seq
MIRT2447934	hsa-miR-4676-5p	CLIP-seq
MIRT921833	hsa-miR-4680-5p	CLIP-seq
MIRT2447935	hsa-miR-4684-5p	CLIP-seq
MIRT921875	hsa-miR-4691-3p	CLIP-seq
MIRT921835	hsa-miR-4695-3p	CLIP-seq
MIRT2512572	hsa-miR-4722-5p	CLIP-seq
MIRT2208748	hsa-miR-4733-5p	CLIP-seq
MIRT2208749	hsa-miR-4736	CLIP-seq
MIRT921877	hsa-miR-4747-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT2447936	hsa-miR-4755-3p	CLIP-seq
MIRT2512573	hsa-miR-4759	CLIP-seq
MIRT2208750	hsa-miR-4763-3p	CLIP-seq
MIRT2512574	hsa-miR-4777-5p	CLIP-seq
MIRT921839	hsa-miR-4793-3p	CLIP-seq
MIRT2208751	hsa-miR-485-5p	CLIP-seq
MIRT921881	hsa-miR-495	CLIP-seq
MIRT921842	hsa-miR-508-5p	CLIP-seq
MIRT2512575	hsa-miR-518d-5p	CLIP-seq
MIRT2512576	hsa-miR-519b-5p	CLIP-seq
MIRT2512577	hsa-miR-519c-5p	CLIP-seq
MIRT2512578	hsa-miR-520c-5p	CLIP-seq
MIRT2512579	hsa-miR-526a	CLIP-seq
MIRT921843	hsa-miR-532-5p	CLIP-seq
MIRT921844	hsa-miR-548aa	CLIP-seq
MIRT2447937	hsa-miR-548c-3p	CLIP-seq
MIRT921884	hsa-miR-548g	CLIP-seq
MIRT2208752	hsa-miR-550a	CLIP-seq
MIRT2512580	hsa-miR-554	CLIP-seq
MIRT921845	hsa-miR-556-3p	CLIP-seq
MIRT2512581	hsa-miR-558	CLIP-seq
MIRT2512582	hsa-miR-561	CLIP-seq
MIRT921886	hsa-miR-570	CLIP-seq
MIRT2447938	hsa-miR-575	CLIP-seq
MIRT2512583	hsa-miR-577	CLIP-seq
MIRT921887	hsa-miR-590-3p	CLIP-seq
MIRT921888	hsa-miR-603	CLIP-seq
MIRT2512584	hsa-miR-606	CLIP-seq
MIRT921848	hsa-miR-612	CLIP-seq
MIRT921890	hsa-miR-636	CLIP-seq
MIRT921849	hsa-miR-651	CLIP-seq
MIRT921850	hsa-miR-661	CLIP-seq
MIRT2512585	hsa-miR-675	CLIP-seq
MIRT921851	hsa-miR-766	CLIP-seq
MIRT2512586	hsa-miR-802	CLIP-seq
MIRT2512587	hsa-miR-875-5p	CLIP-seq
MIRT2208753	hsa-miR-890	CLIP-seq
MIRT2512588	hsa-miR-944	CLIP-seq
MIRT921895	hsa-miR-96	CLIP-seq
MIRT2512544	hsa-miR-10a	CLIP-seq
MIRT2512545	hsa-miR-10b	CLIP-seq
MIRT2208739	hsa-miR-1179	CLIP-seq
MIRT2208740	hsa-miR-1207-5p	CLIP-seq
MIRT921798	hsa-miR-1236	CLIP-seq
MIRT921855	hsa-miR-1271	CLIP-seq
MIRT2512546	hsa-miR-1273g	CLIP-seq
MIRT921799	hsa-miR-1285	CLIP-seq
MIRT2512547	hsa-miR-1286	CLIP-seq
MIRT2512548	hsa-miR-1290	CLIP-seq
MIRT921856	hsa-miR-1295	CLIP-seq
MIRT921800	hsa-miR-1298	CLIP-seq
MIRT921802	hsa-miR-150	CLIP-seq
MIRT921857	hsa-miR-182	CLIP-seq
MIRT921803	hsa-miR-2052	CLIP-seq
MIRT2512550	hsa-miR-2053	CLIP-seq
MIRT921804	hsa-miR-23a	CLIP-seq
MIRT921805	hsa-miR-23b	CLIP-seq
MIRT921806	hsa-miR-23c	CLIP-seq
MIRT921807	hsa-miR-24	CLIP-seq
MIRT2512551	hsa-miR-28-3p	CLIP-seq
MIRT2208741	hsa-miR-2964a-3p	CLIP-seq
MIRT2512552	hsa-miR-31	CLIP-seq
MIRT2512553	hsa-miR-3125	CLIP-seq
MIRT2512554	hsa-miR-3144-3p	CLIP-seq
MIRT921862	hsa-miR-3157-5p	CLIP-seq
MIRT921809	hsa-miR-3187-5p	CLIP-seq
MIRT2512556	hsa-miR-3200-3p	CLIP-seq
MIRT921810	hsa-miR-323-3p	CLIP-seq
MIRT921863	hsa-miR-329	CLIP-seq
MIRT2512557	hsa-miR-335	CLIP-seq
MIRT921812	hsa-miR-342-3p	CLIP-seq
MIRT921813	hsa-miR-3606	CLIP-seq
MIRT921814	hsa-miR-3613-3p	CLIP-seq
MIRT2512558	hsa-miR-361-5p	CLIP-seq
MIRT2447931	hsa-miR-3622b-5p	CLIP-seq
MIRT921865	hsa-miR-362-3p	CLIP-seq
MIRT2208742	hsa-miR-3665	CLIP-seq
MIRT2512559	hsa-miR-3674	CLIP-seq
MIRT2512560	hsa-miR-3691-3p	CLIP-seq
MIRT1973060	hsa-miR-3692	CLIP-seq
MIRT921819	hsa-miR-371-5p	CLIP-seq
MIRT921820	hsa-miR-371b-5p	CLIP-seq
MIRT1973061	hsa-miR-377	CLIP-seq
MIRT2512561	hsa-miR-380	CLIP-seq
MIRT921866	hsa-miR-382	CLIP-seq
MIRT2512562	hsa-miR-3916	CLIP-seq
MIRT2208743	hsa-miR-3929	CLIP-seq
MIRT921867	hsa-miR-3941	CLIP-seq
MIRT2208744	hsa-miR-4274	CLIP-seq
MIRT2512563	hsa-miR-4318	CLIP-seq
MIRT2512564	hsa-miR-4320	CLIP-seq
MIRT2208745	hsa-miR-4419b	CLIP-seq
MIRT921829	hsa-miR-4420	CLIP-seq
MIRT921830	hsa-miR-4433	CLIP-seq
MIRT2208746	hsa-miR-4468	CLIP-seq
MIRT2208747	hsa-miR-4478	CLIP-seq
MIRT2512566	hsa-miR-4495	CLIP-seq
MIRT1973062	hsa-miR-4501	CLIP-seq
MIRT2512567	hsa-miR-4517	CLIP-seq
MIRT2512568	hsa-miR-452	CLIP-seq
MIRT2512570	hsa-miR-4539	CLIP-seq
MIRT2447932	hsa-miR-4645-5p	CLIP-seq
MIRT921872	hsa-miR-466	CLIP-seq
MIRT921832	hsa-miR-4662a-5p	CLIP-seq
MIRT921874	hsa-miR-4672	CLIP-seq
MIRT2447933	hsa-miR-4673	CLIP-seq
MIRT2512571	hsa-miR-4676-3p	CLIP-seq
MIRT2447934	hsa-miR-4676-5p	CLIP-seq
MIRT2447935	hsa-miR-4684-5p	CLIP-seq
MIRT921875	hsa-miR-4691-3p	CLIP-seq
MIRT921835	hsa-miR-4695-3p	CLIP-seq
MIRT2512572	hsa-miR-4722-5p	CLIP-seq
MIRT2208748	hsa-miR-4733-5p	CLIP-seq
MIRT2208749	hsa-miR-4736	CLIP-seq
MIRT921877	hsa-miR-4747-3p	CLIP-seq
MIRT921836	hsa-miR-4753-3p	CLIP-seq
MIRT2447936	hsa-miR-4755-3p	CLIP-seq
MIRT2512573	hsa-miR-4759	CLIP-seq
MIRT2208750	hsa-miR-4763-3p	CLIP-seq
MIRT2512574	hsa-miR-4777-5p	CLIP-seq
MIRT921839	hsa-miR-4793-3p	CLIP-seq
MIRT2208751	hsa-miR-485-5p	CLIP-seq
MIRT921881	hsa-miR-495	CLIP-seq
MIRT921842	hsa-miR-508-5p	CLIP-seq
MIRT2512575	hsa-miR-518d-5p	CLIP-seq
MIRT2512576	hsa-miR-519b-5p	CLIP-seq
MIRT2512577	hsa-miR-519c-5p	CLIP-seq
MIRT2512578	hsa-miR-520c-5p	CLIP-seq
MIRT2512579	hsa-miR-526a	CLIP-seq
MIRT921844	hsa-miR-548aa	CLIP-seq
MIRT2447937	hsa-miR-548c-3p	CLIP-seq
MIRT921884	hsa-miR-548g	CLIP-seq
MIRT2208752	hsa-miR-550a	CLIP-seq
MIRT2512580	hsa-miR-554	CLIP-seq
MIRT921845	hsa-miR-556-3p	CLIP-seq
MIRT2512582	hsa-miR-561	CLIP-seq
MIRT2447938	hsa-miR-575	CLIP-seq
MIRT2512583	hsa-miR-577	CLIP-seq
MIRT921887	hsa-miR-590-3p	CLIP-seq
MIRT921888	hsa-miR-603	CLIP-seq
MIRT2512584	hsa-miR-606	CLIP-seq
MIRT921848	hsa-miR-612	CLIP-seq
MIRT921850	hsa-miR-661	CLIP-seq
MIRT2512585	hsa-miR-675	CLIP-seq
MIRT921851	hsa-miR-766	CLIP-seq
MIRT2512586	hsa-miR-802	CLIP-seq
MIRT2512587	hsa-miR-875-5p	CLIP-seq
MIRT2208753	hsa-miR-890	CLIP-seq
MIRT2512588	hsa-miR-944	CLIP-seq
MIRT921895	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004497	Function	Monooxygenase activity	IEA
GO:0005506	Function	Iron ion binding	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006694	Process	Steroid biosynthetic process	IDA	20149798
GO:0006694	Process	Steroid biosynthetic process	IEA
GO:0006695	Process	Cholesterol biosynthetic process	IEA
GO:0006695	Process	Cholesterol biosynthetic process	TAS
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008398	Function	Sterol 14-demethylase activity	IDA	20149798
GO:0008398	Function	Sterol 14-demethylase activity	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016125	Process	Sterol metabolic process	TAS
GO:0016126	Process	Sterol biosynthetic process	IEA
GO:0016491	Function	Oxidoreductase activity	IBA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016705	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
GO:0016712	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	TAS
GO:0020037	Function	Heme binding	IDA	20149798
GO:0020037	Function	Heme binding	IEA
GO:0033488	Process	Cholesterol biosynthetic process via 24,25-dihydrolanosterol	IBA
GO:0042177	Process	Negative regulation of protein catabolic process	IEA
GO:0042177	Process	Negative regulation of protein catabolic process	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0050709	Process	Negative regulation of protein secretion	IEA
GO:0050709	Process	Negative regulation of protein secretion	ISS
GO:1900222	Process	Negative regulation of amyloid-beta clearance	IEA
GO:1900222	Process	Negative regulation of amyloid-beta clearance	ISS

Other IDs

• MIM: 601637
• HGNC: 2649
• e!Ensembl: ENSG00000001630

Protein

• UniProt ID: Q16850
• Protein name: Lanosterol 14-alpha demethylase (LDM) (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51A1) (CYP51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase)
• Protein function: Sterol 14alpha-demethylase that plays a critical role in the cholesterol biosynthesis pathway, being cholesterol the major sterol component in mammalian membranes as well as a precursor for bile acid and steroid hormone synthesis (PubMed:2014979
• PDB: 3JUS, 3JUV, 3LD6, 4UHI, 4UHL, 6Q2T, 6UEZ, 8SBI, 8SS0
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00067	p450	61 → 496	Cytochrome P450	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung. {ECO:0000269|PubMed:8619637}.
• Sequence:

  MLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGVKS
  PPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNS
  KNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETK
  EYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWL
  LPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLTDDE
  VAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDL
  NLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLD
  FNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFP
  TVNYTTMIHTPENPVIRYKRRSK

• Sequence length: 503

Pathways

KEGG:

Steroid biosynthesis
Metabolic pathways

Reactome:

Cholesterol biosynthesis
Endogenous sterols
Activation of gene expression by SREBF (SREBP)
EGR2 and SOX10-mediated initiation of Schwann cell myelination

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CATARACT	—	Disgenet Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL CATARACT	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL CATARACT, SEVERE NEONATAL HEPATOPATHY, GLOBAL DEVELOPMENTAL DELAY SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL CATARACT-SEVERE NEONATAL HEPATOPATHY-GLOBAL DEVELOPMENTAL DELAY SYNDROME	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CYP51A1-related disorder	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental cataract	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DYSLEXIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell carcinoma of the head and neck	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Alzheimer Disease	Associate	36769199	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	34513998	★☆☆☆☆ Found in Text Mining only
Cataract	Associate	22935719	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal Neoplasms	Associate	27341022	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Associate	26153245	★☆☆☆☆ Found in Text Mining only
Crohn Disease	Associate	35872023	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	19667409, 27341022, 28962550, 33924405	★☆☆☆☆ Found in Text Mining only