Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	159195
Gene name Gene Name - the full gene name approved by the HGNC.	Ubiquitin specific peptidase 54
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	USP54
Synonyms (NCBI Gene) Gene synonyms aliases	C10orf29, bA137L10.3, bA137L10.4
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q22.2

Show/Hide all(366)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024483	hsa-miR-215-5p	Microarray	19074876
MIRT026658	hsa-miR-192-5p	Microarray	19074876
MIRT052169	hsa-let-7b-5p	CLASH	23622248
MIRT035898	hsa-miR-1303	CLASH	23622248
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480362	hsa-miR-1224-5p	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT1480367	hsa-miR-150	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT1480370	hsa-miR-299-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT1480372	hsa-miR-3152-3p	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT1480377	hsa-miR-3688-5p	CLIP-seq
MIRT1480378	hsa-miR-3915	CLIP-seq
MIRT1480379	hsa-miR-3921	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT1480385	hsa-miR-4328	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT1480388	hsa-miR-4461	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT1480391	hsa-miR-4522	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT1480394	hsa-miR-4649-3p	CLIP-seq
MIRT1480395	hsa-miR-4653-5p	CLIP-seq
MIRT1480396	hsa-miR-4687-3p	CLIP-seq
MIRT1480397	hsa-miR-4689	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480401	hsa-miR-4714-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT1480404	hsa-miR-4751	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT1480406	hsa-miR-520d-5p	CLIP-seq
MIRT1480407	hsa-miR-524-5p	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT1480409	hsa-miR-582-5p	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT1480411	hsa-miR-629	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2144519	hsa-miR-106a	CLIP-seq
MIRT2144520	hsa-miR-106b	CLIP-seq
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2144523	hsa-miR-1302	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2144524	hsa-miR-17	CLIP-seq
MIRT2144525	hsa-miR-197	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2144526	hsa-miR-20a	CLIP-seq
MIRT2144527	hsa-miR-20b	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2144528	hsa-miR-3122	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT2144529	hsa-miR-3199	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2144532	hsa-miR-3913-5p	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2144535	hsa-miR-4298	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT2144538	hsa-miR-4716-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144540	hsa-miR-483-5p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144542	hsa-miR-5095	CLIP-seq
MIRT2144543	hsa-miR-5096	CLIP-seq
MIRT2144544	hsa-miR-519d	CLIP-seq
MIRT2144545	hsa-miR-548aa	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2144548	hsa-miR-93	CLIP-seq
MIRT2144519	hsa-miR-106a	CLIP-seq
MIRT2144520	hsa-miR-106b	CLIP-seq
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2144523	hsa-miR-1302	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2144524	hsa-miR-17	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2144525	hsa-miR-197	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2144526	hsa-miR-20a	CLIP-seq
MIRT2144527	hsa-miR-20b	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2144528	hsa-miR-3122	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2364864	hsa-miR-3149	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT2144529	hsa-miR-3199	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT2364866	hsa-miR-3529	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2364868	hsa-miR-3622a-5p	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2364870	hsa-miR-379	CLIP-seq
MIRT2144532	hsa-miR-3913-5p	CLIP-seq
MIRT2364871	hsa-miR-3934	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT2364872	hsa-miR-4269	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2144535	hsa-miR-4298	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT2364873	hsa-miR-4438	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364875	hsa-miR-4451	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT2364879	hsa-miR-4650-3p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT2144538	hsa-miR-4716-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2364881	hsa-miR-4735-5p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2364883	hsa-miR-4772-3p	CLIP-seq
MIRT2364884	hsa-miR-4775	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2364885	hsa-miR-4794	CLIP-seq
MIRT2144540	hsa-miR-483-5p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144542	hsa-miR-5095	CLIP-seq
MIRT2144543	hsa-miR-5096	CLIP-seq
MIRT2144544	hsa-miR-519d	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2364886	hsa-miR-590-3p	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq
MIRT2144548	hsa-miR-93	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2658689	hsa-miR-1207-5p	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT2658690	hsa-miR-1261	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2658691	hsa-miR-1285	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2658692	hsa-miR-1307	CLIP-seq
MIRT2658693	hsa-miR-140-3p	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2658694	hsa-miR-1972	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2658695	hsa-miR-199a-3p	CLIP-seq
MIRT2658696	hsa-miR-199b-3p	CLIP-seq
MIRT2658697	hsa-miR-2052	CLIP-seq
MIRT2658698	hsa-miR-221	CLIP-seq
MIRT2658699	hsa-miR-222	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2658700	hsa-miR-3064-3p	CLIP-seq
MIRT2658701	hsa-miR-3129-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2658702	hsa-miR-3165	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT2658703	hsa-miR-3187-5p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2658704	hsa-miR-369-3p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT2658705	hsa-miR-4638-5p	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT2658706	hsa-miR-4666-5p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT2658707	hsa-miR-4763-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2364883	hsa-miR-4772-3p	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2658708	hsa-miR-612	CLIP-seq
MIRT2658709	hsa-miR-619	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2658710	hsa-miR-7	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq
MIRT2658689	hsa-miR-1207-5p	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2658691	hsa-miR-1285	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2658692	hsa-miR-1307	CLIP-seq
MIRT2658693	hsa-miR-140-3p	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2658694	hsa-miR-1972	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2658695	hsa-miR-199a-3p	CLIP-seq
MIRT2658696	hsa-miR-199b-3p	CLIP-seq
MIRT2658697	hsa-miR-2052	CLIP-seq
MIRT2658698	hsa-miR-221	CLIP-seq
MIRT2658699	hsa-miR-222	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2658700	hsa-miR-3064-3p	CLIP-seq
MIRT2658701	hsa-miR-3129-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT2658703	hsa-miR-3187-5p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2694842	hsa-miR-3660	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2658704	hsa-miR-369-3p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2694843	hsa-miR-4526	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT2658705	hsa-miR-4638-5p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT2658706	hsa-miR-4666-5p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2694844	hsa-miR-4728-3p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT2658707	hsa-miR-4763-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2658708	hsa-miR-612	CLIP-seq
MIRT2658709	hsa-miR-619	CLIP-seq
MIRT2694845	hsa-miR-628-5p	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2658710	hsa-miR-7	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq

Show/Hide all(4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004843	Function	Thiol-dependent ubiquitin-specific protease activity	IEA
GO:0005515	Function	Protein binding	IPI	16713569, 25416956
GO:0016579	Process	Protein deubiquitination	IEA
GO:0018215	Process	Protein phosphopantetheinylation	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q70EL1

Protein name

Ubiquitin carboxyl-terminal hydrolase 54 (EC 3.4.19.12) (Ubiquitin-specific peptidase 54)

Protein function

Deubiquitinase that specifically mediates 'Lys-63'-linked deubiquitination of substrates with a polyubiquitin chain composed of at least 3 ubiquitins (PubMed:39587316). Specifically recognizes ubiquitin chain in position S2 and catalyzes cleavag

PDB

8C61

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00443	UCH	31 → 349	Ubiquitin carboxyl-terminal hydrolase	Family

Tissue specificity

TISSUE SPECIFICITY: Weakly expressed in a few tissues. {ECO:0000269|PubMed:14715245}.

Sequence

MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS
FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD
AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ
MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM
NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG
KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ
DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG
TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH
SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP
DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT
QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES
GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS
MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD
LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS
THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ
VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE
VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI
AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS
SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ
GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE
ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL
DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE
SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL
HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS
NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT
SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP
GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS
DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ
HSQW

Sequence length

1684

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	28640357
Neoplasms	Associate	34398824
Squamous Cell Carcinoma of Head and Neck	Associate	34398824
Virus Diseases	Associate	35654986

USP54 (ubiquitin specific peptidase 54)