Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	159195
Gene name Gene Name - the full gene name approved by the HGNC.	Ubiquitin specific peptidase 54
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	USP54
Synonyms (NCBI Gene) Gene synonyms aliases	C10orf29, bA137L10.3, bA137L10.4
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q22.2

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024483	hsa-miR-215-5p	Microarray	19074876
MIRT026658	hsa-miR-192-5p	Microarray	19074876
MIRT052169	hsa-let-7b-5p	CLASH	23622248
MIRT035898	hsa-miR-1303	CLASH	23622248
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480362	hsa-miR-1224-5p	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT1480367	hsa-miR-150	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT1480370	hsa-miR-299-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT1480372	hsa-miR-3152-3p	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT1480377	hsa-miR-3688-5p	CLIP-seq
MIRT1480378	hsa-miR-3915	CLIP-seq
MIRT1480379	hsa-miR-3921	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT1480385	hsa-miR-4328	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT1480388	hsa-miR-4461	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT1480391	hsa-miR-4522	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT1480394	hsa-miR-4649-3p	CLIP-seq
MIRT1480395	hsa-miR-4653-5p	CLIP-seq
MIRT1480396	hsa-miR-4687-3p	CLIP-seq
MIRT1480397	hsa-miR-4689	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480401	hsa-miR-4714-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT1480404	hsa-miR-4751	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT1480406	hsa-miR-520d-5p	CLIP-seq
MIRT1480407	hsa-miR-524-5p	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT1480409	hsa-miR-582-5p	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT1480411	hsa-miR-629	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2144519	hsa-miR-106a	CLIP-seq
MIRT2144520	hsa-miR-106b	CLIP-seq
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2144523	hsa-miR-1302	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2144524	hsa-miR-17	CLIP-seq
MIRT2144525	hsa-miR-197	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2144526	hsa-miR-20a	CLIP-seq
MIRT2144527	hsa-miR-20b	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2144528	hsa-miR-3122	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT2144529	hsa-miR-3199	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2144532	hsa-miR-3913-5p	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2144535	hsa-miR-4298	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT2144538	hsa-miR-4716-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144540	hsa-miR-483-5p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144542	hsa-miR-5095	CLIP-seq
MIRT2144543	hsa-miR-5096	CLIP-seq
MIRT2144544	hsa-miR-519d	CLIP-seq
MIRT2144545	hsa-miR-548aa	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2144548	hsa-miR-93	CLIP-seq
MIRT2144519	hsa-miR-106a	CLIP-seq
MIRT2144520	hsa-miR-106b	CLIP-seq
MIRT1480360	hsa-miR-1193	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2144523	hsa-miR-1302	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2144524	hsa-miR-17	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2144525	hsa-miR-197	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2144526	hsa-miR-20a	CLIP-seq
MIRT2144527	hsa-miR-20b	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2144528	hsa-miR-3122	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2364864	hsa-miR-3149	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT1480373	hsa-miR-3187-3p	CLIP-seq
MIRT2144529	hsa-miR-3199	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT2364866	hsa-miR-3529	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2364868	hsa-miR-3622a-5p	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2364870	hsa-miR-379	CLIP-seq
MIRT2144532	hsa-miR-3913-5p	CLIP-seq
MIRT2364871	hsa-miR-3934	CLIP-seq
MIRT1480380	hsa-miR-4259	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT2364872	hsa-miR-4269	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2144535	hsa-miR-4298	CLIP-seq
MIRT1480386	hsa-miR-4425	CLIP-seq
MIRT1480387	hsa-miR-4435	CLIP-seq
MIRT2364873	hsa-miR-4438	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364875	hsa-miR-4451	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT2364879	hsa-miR-4650-3p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT1480398	hsa-miR-4701-5p	CLIP-seq
MIRT1480399	hsa-miR-4703-3p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480402	hsa-miR-4715-5p	CLIP-seq
MIRT2144538	hsa-miR-4716-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2364881	hsa-miR-4735-5p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2364883	hsa-miR-4772-3p	CLIP-seq
MIRT2364884	hsa-miR-4775	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2364885	hsa-miR-4794	CLIP-seq
MIRT2144540	hsa-miR-483-5p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144542	hsa-miR-5095	CLIP-seq
MIRT2144543	hsa-miR-5096	CLIP-seq
MIRT2144544	hsa-miR-519d	CLIP-seq
MIRT1480408	hsa-miR-548s	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT1480410	hsa-miR-588	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2364886	hsa-miR-590-3p	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq
MIRT2144548	hsa-miR-93	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2658689	hsa-miR-1207-5p	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT2658690	hsa-miR-1261	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2658691	hsa-miR-1285	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2658692	hsa-miR-1307	CLIP-seq
MIRT2658693	hsa-miR-140-3p	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2658694	hsa-miR-1972	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2658695	hsa-miR-199a-3p	CLIP-seq
MIRT2658696	hsa-miR-199b-3p	CLIP-seq
MIRT2658697	hsa-miR-2052	CLIP-seq
MIRT2658698	hsa-miR-221	CLIP-seq
MIRT2658699	hsa-miR-222	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2658700	hsa-miR-3064-3p	CLIP-seq
MIRT2658701	hsa-miR-3129-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2658702	hsa-miR-3165	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT2658703	hsa-miR-3187-5p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT2144530	hsa-miR-34a	CLIP-seq
MIRT2144531	hsa-miR-34c-5p	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2658704	hsa-miR-369-3p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT2144534	hsa-miR-4284	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT2144536	hsa-miR-449a	CLIP-seq
MIRT2144537	hsa-miR-449b	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT2658705	hsa-miR-4638-5p	CLIP-seq
MIRT1480393	hsa-miR-4639-3p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT2658706	hsa-miR-4666-5p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT2658707	hsa-miR-4763-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2364883	hsa-miR-4772-3p	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2658708	hsa-miR-612	CLIP-seq
MIRT2658709	hsa-miR-619	CLIP-seq
MIRT1480412	hsa-miR-640	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2658710	hsa-miR-7	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq
MIRT2658689	hsa-miR-1207-5p	CLIP-seq
MIRT1480361	hsa-miR-122	CLIP-seq
MIRT1480363	hsa-miR-1244	CLIP-seq
MIRT2364859	hsa-miR-1245b-5p	CLIP-seq
MIRT2144521	hsa-miR-1257	CLIP-seq
MIRT1480364	hsa-miR-1273f	CLIP-seq
MIRT2658691	hsa-miR-1285	CLIP-seq
MIRT1480365	hsa-miR-1289	CLIP-seq
MIRT2144522	hsa-miR-129-5p	CLIP-seq
MIRT2658692	hsa-miR-1307	CLIP-seq
MIRT2658693	hsa-miR-140-3p	CLIP-seq
MIRT1480366	hsa-miR-143	CLIP-seq
MIRT2364860	hsa-miR-146b-3p	CLIP-seq
MIRT2364861	hsa-miR-1909	CLIP-seq
MIRT2658694	hsa-miR-1972	CLIP-seq
MIRT1480368	hsa-miR-1976	CLIP-seq
MIRT2658695	hsa-miR-199a-3p	CLIP-seq
MIRT2658696	hsa-miR-199b-3p	CLIP-seq
MIRT2658697	hsa-miR-2052	CLIP-seq
MIRT2658698	hsa-miR-221	CLIP-seq
MIRT2658699	hsa-miR-222	CLIP-seq
MIRT1480369	hsa-miR-2392	CLIP-seq
MIRT2364862	hsa-miR-2964a-5p	CLIP-seq
MIRT2658700	hsa-miR-3064-3p	CLIP-seq
MIRT2658701	hsa-miR-3129-5p	CLIP-seq
MIRT1480371	hsa-miR-3135b	CLIP-seq
MIRT2364863	hsa-miR-3142	CLIP-seq
MIRT2364865	hsa-miR-3173-5p	CLIP-seq
MIRT2658703	hsa-miR-3187-5p	CLIP-seq
MIRT1480374	hsa-miR-3198	CLIP-seq
MIRT1480375	hsa-miR-320e	CLIP-seq
MIRT1480376	hsa-miR-3614-3p	CLIP-seq
MIRT2364867	hsa-miR-3616-3p	CLIP-seq
MIRT2694842	hsa-miR-3660	CLIP-seq
MIRT2364869	hsa-miR-3682-3p	CLIP-seq
MIRT2658704	hsa-miR-369-3p	CLIP-seq
MIRT2144533	hsa-miR-4266	CLIP-seq
MIRT1480381	hsa-miR-4279	CLIP-seq
MIRT1480382	hsa-miR-4294	CLIP-seq
MIRT1480383	hsa-miR-4297	CLIP-seq
MIRT1480384	hsa-miR-4309	CLIP-seq
MIRT2364874	hsa-miR-4443	CLIP-seq
MIRT2364876	hsa-miR-4464	CLIP-seq
MIRT1480389	hsa-miR-4466	CLIP-seq
MIRT1480390	hsa-miR-4480	CLIP-seq
MIRT2364877	hsa-miR-4502	CLIP-seq
MIRT2694843	hsa-miR-4526	CLIP-seq
MIRT2364878	hsa-miR-4532	CLIP-seq
MIRT1480392	hsa-miR-4534	CLIP-seq
MIRT2658705	hsa-miR-4638-5p	CLIP-seq
MIRT2364880	hsa-miR-4660	CLIP-seq
MIRT2658706	hsa-miR-4666-5p	CLIP-seq
MIRT1480400	hsa-miR-4708-5p	CLIP-seq
MIRT1480403	hsa-miR-4722-3p	CLIP-seq
MIRT2694844	hsa-miR-4728-3p	CLIP-seq
MIRT2364882	hsa-miR-4748	CLIP-seq
MIRT2658707	hsa-miR-4763-3p	CLIP-seq
MIRT1480405	hsa-miR-4770	CLIP-seq
MIRT2144539	hsa-miR-4781-3p	CLIP-seq
MIRT2144541	hsa-miR-498	CLIP-seq
MIRT2144546	hsa-miR-580	CLIP-seq
MIRT2144547	hsa-miR-589	CLIP-seq
MIRT2658708	hsa-miR-612	CLIP-seq
MIRT2658709	hsa-miR-619	CLIP-seq
MIRT2694845	hsa-miR-628-5p	CLIP-seq
MIRT2364887	hsa-miR-645	CLIP-seq
MIRT1480413	hsa-miR-675	CLIP-seq
MIRT2658710	hsa-miR-7	CLIP-seq
MIRT2364888	hsa-miR-874	CLIP-seq
MIRT2364889	hsa-miR-885-3p	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004843	Function	Cysteine-type deubiquitinase activity	IDA	36590171
GO:0004843	Function	Cysteine-type deubiquitinase activity	IEA
GO:0005515	Function	Protein binding	IPI	16713569, 25416956, 32296183, 32353859, 32814053, 33060197, 33961781, 34819669, 35914814, 36217030
GO:0006508	Process	Proteolysis	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008234	Function	Cysteine-type peptidase activity	IEA
GO:0016579	Process	Protein deubiquitination	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0061578	Function	K63-linked deubiquitinase activity	IDA	39587316
GO:0061578	Function	K63-linked deubiquitinase activity	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q70EL1

Protein name

Ubiquitin carboxyl-terminal hydrolase 54 (EC 3.4.19.12) (Ubiquitin-specific peptidase 54)

Protein function

Deubiquitinase that specifically mediates 'Lys-63'-linked deubiquitination of substrates with a polyubiquitin chain composed of at least 3 ubiquitins (PubMed:39587316). Specifically recognizes ubiquitin chain in position S2 and catalyzes cleavag

PDB

8C61

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00443	UCH	31 → 349	Ubiquitin carboxyl-terminal hydrolase	Family

Tissue specificity

TISSUE SPECIFICITY: Weakly expressed in a few tissues. {ECO:0000269|PubMed:14715245}.

Sequence

MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS
FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD
AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ
MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM
NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG
KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ
DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG
TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH
SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP
DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT
QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES
GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS
MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD
LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS
THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ
VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE
VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI
AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS
SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ
GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE
ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL
DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE
SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL
HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS
NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT
SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP
GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS
DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ
HSQW

Sequence length

1684

Interactions

View interactions

USP54 (ubiquitin specific peptidase 54)