Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
158866
Gene name Gene Name - the full gene name approved by the HGNC.
ZDHHC palmitoyltransferase 15
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZDHHC15
Synonyms (NCBI Gene) Gene synonyms aliases
DHHC15, MRX91
Disease Acronyms (UniProt) Disease acronyms from UniProt database
MRX91
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq13.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017787 hsa-miR-335-5p Microarray 18185580
MIRT019337 hsa-miR-148b-3p Microarray 17612493
MIRT645556 hsa-miR-3177-5p HITS-CLIP 23313552
MIRT645555 hsa-miR-6867-5p HITS-CLIP 23313552
MIRT645554 hsa-miR-4666a-5p HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane ISS
GO:0005515 Function Protein binding IPI 32296183
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0005794 Component Golgi apparatus IDA 16647879
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
300576 20342 ENSG00000102383
Protein
UniProt ID Q96MV8
Protein name Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Acyltransferase ZDHHC15) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 15) (DHHC-15)
Protein function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:18817523, PubMed:23034182). Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myrista
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01529 DHHC 125 249 DHHC palmitoyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Expressed in placenta, liver, lung, kidney, heart and brain. {ECO:0000269|PubMed:15915161}.
Sequence
MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLIL
YHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVY
TRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAY
SVLYCLYIATTVFSYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSR
NKTTLEAFC
TPVFTSGPEKNGFNLGFIKNIQQVFGDKKKFWLIPIGSSPGDGHSFPMRSM
NESQNPLLANEETWEDNEDDNQDYPEGSSSLAVETET
Sequence length 337
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Mental retardation MENTAL RETARDATION, X-LINKED 91 (disorder) rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315
View all (1024 more)
15915161
Unknown
Disease term Disease name Evidence References Source
Neurodevelopmental Disorders X-linked complex neurodevelopmental disorder GenCC
Associations from Text Mining
Disease Name Relationship Type References
Amenorrhea Associate 25747126
Glioma Associate 37161425
Intellectual Disability Associate 23871722