Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	158219
Gene name Gene Name - the full gene name approved by the HGNC.	Tetratricopeptide repeat domain 39B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TTC39B
Synonyms (NCBI Gene) Gene synonyms aliases	C9orf52
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9p22.3

Show/Hide all(240)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018991	hsa-miR-335-5p	Microarray	18185580
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT679003	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT679002	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT679001	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT679000	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT678999	hsa-miR-3689c	HITS-CLIP	23824327
MIRT678998	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT678997	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT652072	hsa-miR-4517	HITS-CLIP	23824327
MIRT652071	hsa-miR-425-5p	HITS-CLIP	23824327
MIRT652070	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT652068	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT652069	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT652067	hsa-miR-3117-5p	HITS-CLIP	23824327
MIRT652066	hsa-miR-623	HITS-CLIP	23824327
MIRT652065	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT652064	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT652062	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT652063	hsa-miR-4760-5p	HITS-CLIP	23824327
MIRT652061	hsa-miR-8061	HITS-CLIP	23824327
MIRT652060	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT652059	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT541696	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT452404	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT452403	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT452402	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT452400	hsa-miR-4257	PAR-CLIP	23592263
MIRT452401	hsa-miR-4459	PAR-CLIP	23592263
MIRT452399	hsa-miR-665	PAR-CLIP	23592263
MIRT452398	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT452397	hsa-miR-1827	PAR-CLIP	23592263
MIRT452396	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452395	hsa-miR-6086	PAR-CLIP	23592263
MIRT452394	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT452393	hsa-miR-3612	PAR-CLIP	23592263
MIRT452392	hsa-miR-650	PAR-CLIP	23592263
MIRT452391	hsa-miR-4536-5p	PAR-CLIP	23592263
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT679003	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT679002	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT679001	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT679000	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT678999	hsa-miR-3689c	HITS-CLIP	23824327
MIRT678998	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT678997	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT652072	hsa-miR-4517	HITS-CLIP	23824327
MIRT652071	hsa-miR-425-5p	HITS-CLIP	23824327
MIRT652070	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT652068	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT652069	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT652067	hsa-miR-3117-5p	HITS-CLIP	23824327
MIRT652066	hsa-miR-623	HITS-CLIP	23824327
MIRT652065	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT652064	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT652062	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT652063	hsa-miR-4760-5p	HITS-CLIP	23824327
MIRT652061	hsa-miR-8061	HITS-CLIP	23824327
MIRT652060	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT652059	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT652058	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT652057	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT652056	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT652055	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT652054	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT652053	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT652052	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT652051	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT652050	hsa-miR-7977	HITS-CLIP	23824327
MIRT652049	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT652048	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT652047	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT652046	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT652045	hsa-miR-3122	HITS-CLIP	23824327
MIRT652044	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT652043	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT652042	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT541695	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT541694	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT541696	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT541696	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541695	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541694	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT452404	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT452403	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT452402	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT452400	hsa-miR-4257	PAR-CLIP	23592263
MIRT452401	hsa-miR-4459	PAR-CLIP	23592263
MIRT452399	hsa-miR-665	PAR-CLIP	23592263
MIRT452398	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT452397	hsa-miR-1827	PAR-CLIP	23592263
MIRT452396	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT452395	hsa-miR-6086	PAR-CLIP	23592263
MIRT452394	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT452393	hsa-miR-3612	PAR-CLIP	23592263
MIRT452392	hsa-miR-650	PAR-CLIP	23592263
MIRT452391	hsa-miR-4536-5p	PAR-CLIP	23592263
MIRT1461580	hsa-miR-128	CLIP-seq
MIRT1461581	hsa-miR-24	CLIP-seq
MIRT1461582	hsa-miR-27a	CLIP-seq
MIRT1461583	hsa-miR-27b	CLIP-seq
MIRT1461584	hsa-miR-3065-5p	CLIP-seq
MIRT1461585	hsa-miR-4284	CLIP-seq
MIRT1461586	hsa-miR-4670-3p	CLIP-seq
MIRT1461587	hsa-miR-606	CLIP-seq
MIRT1461588	hsa-miR-642b	CLIP-seq
MIRT1461589	hsa-miR-1224-5p	CLIP-seq
MIRT1461590	hsa-miR-3148	CLIP-seq
MIRT1461591	hsa-miR-3915	CLIP-seq
MIRT1461592	hsa-miR-3928	CLIP-seq
MIRT1461593	hsa-miR-4689	CLIP-seq
MIRT1461594	hsa-miR-23a	CLIP-seq
MIRT1461595	hsa-miR-23b	CLIP-seq
MIRT1461596	hsa-miR-23c	CLIP-seq
MIRT1461597	hsa-miR-323-3p	CLIP-seq
MIRT1461598	hsa-miR-4528	CLIP-seq
MIRT1461599	hsa-miR-4775	CLIP-seq
MIRT1461600	hsa-miR-5096	CLIP-seq
MIRT1461601	hsa-miR-590-3p	CLIP-seq
MIRT2138721	hsa-miR-4457	CLIP-seq
MIRT2138722	hsa-miR-513b	CLIP-seq
MIRT2138723	hsa-miR-593	CLIP-seq
MIRT1461580	hsa-miR-128	CLIP-seq
MIRT2694438	hsa-miR-4279	CLIP-seq
MIRT2694439	hsa-miR-4506	CLIP-seq
MIRT2694440	hsa-miR-4509	CLIP-seq
MIRT2694441	hsa-miR-548m	CLIP-seq
MIRT1461588	hsa-miR-642b	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0006629	Process	Lipid metabolic process	IEA
GO:0010874	Process	Regulation of cholesterol efflux	IBA	21873635
GO:0010874	Process	Regulation of cholesterol efflux	ISS
GO:0010887	Process	Negative regulation of cholesterol storage	IBA	21873635
GO:0010887	Process	Negative regulation of cholesterol storage	ISS
GO:0042632	Process	Cholesterol homeostasis	IBA	21873635
GO:0042632	Process	Cholesterol homeostasis	ISS
GO:0090181	Process	Regulation of cholesterol metabolic process	IBA	21873635
GO:0090181	Process	Regulation of cholesterol metabolic process	ISS

MIM	HGNC	e!Ensembl
613574	23704	ENSG00000155158

Protein

UniProt ID

Q5VTQ0

Protein name

Tetratricopeptide repeat protein 39B (TPR repeat protein 39B)

Protein function

Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10300	DUF3808	140 → 598	Protein of unknown function (DUF3808)	Family

Sequence

MDAVLACRLRGRGNRVAALRPRPRPGGSAGPSPFALLCAGLSPEPRAGVGSEFPAWFLGG
SSQRRNMALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGAS
TVSSSSSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQA
VLTFEQQDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYA
ECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGG
VKLGSGAFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAF
HTYISLILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCI
SVQEEWKQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLP
EEDVVATNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEM
MYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQR
PLQAELCYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYS
LESRLHFRIQAALHLWRKPSSD

Sequence length

682

Interactions

View interactions

Show/Hide Unknown Diseases (7)

Disease term	Disease name	References	Source
Unknown
Coronary heart disease	Coronary heart disease	21347282	ClinVar
Coenzyme Q10 Deficiency	Coenzyme Q10 Deficiency		GWAS
Coronary artery disease	Coronary artery disease		GWAS
Bipolar Disorder	Bipolar Disorder		GWAS
Metabolic Syndrome	Metabolic Syndrome		GWAS
Cholecystitis	Cholecystitis		GWAS
Cholelithiasis	Cholelithiasis		GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Cholelithiasis	Associate	39840844
Endometriosis	Associate	27453397
Gallbladder Diseases	Associate	25920552
Stomach Neoplasms	Associate	40102553

TTC39B (tetratricopeptide repeat domain 39B)