Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1580
Gene name Gene Name - the full gene name approved by the HGNC.
Cytochrome P450 family 4 subfamily B member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CYP4B1
Synonyms (NCBI Gene) Gene synonyms aliases
CYPIVB1, P-450HP
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p33
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein local
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT2208693 hsa-miR-1178 CLIP-seq
MIRT2512497 hsa-miR-1207-5p CLIP-seq
MIRT2512498 hsa-miR-1909 CLIP-seq
MIRT2512499 hsa-miR-296-5p CLIP-seq
MIRT2512500 hsa-miR-4691-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005506 Function Iron ion binding IEA
GO:0005789 Component Endoplasmic reticulum membrane TAS
GO:0018879 Process Biphenyl metabolic process IEA
GO:0019825 Function Oxygen binding TAS 2574990
GO:0020037 Function Heme binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
124075 2644 ENSG00000142973
Protein
UniProt ID P13584
Protein name Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (Cytochrome P450-HP)
Protein function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty aci
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00067 p450 46 501 Cytochrome P450 Domain
Tissue specificity TISSUE SPECIFICITY: Detected in the liver and lung (at protein level). {ECO:0000269|PubMed:12695542}.
Sequence
Sequence length 511
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Fatty acids
Miscellaneous substrates
Eicosanoids
Synthesis of Leukotrienes (LT) and Eoxins (EX)