Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	157
Gene name	G protein-coupled receptor kinase 3
Gene symbol	GRK3
Synonyms (NCBI Gene)	ADRBK2BARK2
Chromosome	22
Chromosome location	22q12.1
Summary	The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic rec

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Show/Hide all (262)

miRTarBase ID	miRNA	Experiments	Reference
MIRT613352	hsa-miR-8485	HITS-CLIP	22927820
MIRT613351	hsa-miR-602	HITS-CLIP	22927820
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	22927820
MIRT613349	hsa-miR-609	HITS-CLIP	22927820
MIRT613348	hsa-miR-2052	HITS-CLIP	22927820
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	22927820
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	22927820
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	22927820
MIRT636736	hsa-miR-4709-5p	HITS-CLIP	22927820
MIRT628479	hsa-miR-574-5p	HITS-CLIP	22927820
MIRT660878	hsa-miR-122-5p	HITS-CLIP	22927820
MIRT628485	hsa-miR-6867-5p	HITS-CLIP	22927820
MIRT628484	hsa-miR-7159-5p	HITS-CLIP	22927820
MIRT628483	hsa-miR-505-3p	HITS-CLIP	22927820
MIRT628482	hsa-miR-421	HITS-CLIP	22927820
MIRT628481	hsa-miR-1305	HITS-CLIP	22927820
MIRT628480	hsa-miR-4455	HITS-CLIP	22927820
MIRT613351	hsa-miR-602	HITS-CLIP	23313552
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23313552
MIRT613349	hsa-miR-609	HITS-CLIP	23313552
MIRT613348	hsa-miR-2052	HITS-CLIP	23313552
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23313552
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23313552
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23313552
MIRT400048	hsa-miR-106a-5p	HITS-CLIP	23824327
MIRT400049	hsa-miR-106b-5p	HITS-CLIP	23824327
MIRT400045	hsa-miR-17-5p	HITS-CLIP	23824327
MIRT400046	hsa-miR-20a-5p	HITS-CLIP	23824327
MIRT400050	hsa-miR-20b-5p	HITS-CLIP	23824327
MIRT400052	hsa-miR-519d-3p	HITS-CLIP	23824327
MIRT400051	hsa-miR-526b-3p	HITS-CLIP	23824327
MIRT400047	hsa-miR-93-5p	HITS-CLIP	23824327
MIRT680137	hsa-miR-519a-3p	HITS-CLIP	23824327
MIRT680136	hsa-miR-519b-3p	HITS-CLIP	23824327
MIRT680135	hsa-miR-519c-3p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT680134	hsa-miR-520g-3p	HITS-CLIP	23824327
MIRT680133	hsa-miR-520h	HITS-CLIP	23824327
MIRT680132	hsa-miR-8064	HITS-CLIP	23824327
MIRT680131	hsa-miR-6829-5p	HITS-CLIP	23824327
MIRT680130	hsa-miR-185-3p	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT680129	hsa-miR-518a-5p	HITS-CLIP	23824327
MIRT680128	hsa-miR-527	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT673535	hsa-miR-6796-3p	HITS-CLIP	23824327
MIRT673534	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT673533	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT673532	hsa-miR-4532	HITS-CLIP	23824327
MIRT673531	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT673530	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT673529	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT673528	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT673527	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT673526	hsa-miR-1976	HITS-CLIP	23824327
MIRT673525	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT673524	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT673523	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT673522	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT673521	hsa-miR-3194-3p	HITS-CLIP	23824327
MIRT673520	hsa-miR-1206	HITS-CLIP	23824327
MIRT673519	hsa-miR-4279	HITS-CLIP	23824327
MIRT673518	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT673517	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT628485	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628484	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT628483	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT628482	hsa-miR-421	HITS-CLIP	23824327
MIRT628481	hsa-miR-1305	HITS-CLIP	23824327
MIRT628480	hsa-miR-4455	HITS-CLIP	23824327
MIRT628479	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT628479	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT660878	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT628485	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628484	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT628483	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT628482	hsa-miR-421	HITS-CLIP	23824327
MIRT628481	hsa-miR-1305	HITS-CLIP	23824327
MIRT628480	hsa-miR-4455	HITS-CLIP	23824327
MIRT660877	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT660872	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT660876	hsa-miR-4639-3p	HITS-CLIP	23824327
MIRT660875	hsa-miR-6728-3p	HITS-CLIP	23824327
MIRT660874	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT660873	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT660872	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT660871	hsa-miR-6794-3p	HITS-CLIP	23824327
MIRT660870	hsa-miR-1303	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT636736	hsa-miR-4709-5p	HITS-CLIP	23824327
MIRT628485	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628484	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT628483	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT628482	hsa-miR-421	HITS-CLIP	23824327
MIRT628481	hsa-miR-1305	HITS-CLIP	23824327
MIRT628480	hsa-miR-4455	HITS-CLIP	23824327
MIRT628479	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT636735	hsa-miR-4683	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT636734	hsa-miR-4531	HITS-CLIP	23824327
MIRT636733	hsa-miR-1270	HITS-CLIP	23824327
MIRT636732	hsa-miR-620	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT628485	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT628484	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT628483	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT628482	hsa-miR-421	HITS-CLIP	23824327
MIRT628481	hsa-miR-1305	HITS-CLIP	23824327
MIRT628480	hsa-miR-4455	HITS-CLIP	23824327
MIRT628479	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613352	hsa-miR-8485	HITS-CLIP	23824327
MIRT613351	hsa-miR-602	HITS-CLIP	23824327
MIRT613350	hsa-miR-6747-5p	HITS-CLIP	23824327
MIRT613349	hsa-miR-609	HITS-CLIP	23824327
MIRT613348	hsa-miR-2052	HITS-CLIP	23824327
MIRT613347	hsa-miR-19a-5p	HITS-CLIP	23824327
MIRT613346	hsa-miR-19b-1-5p	HITS-CLIP	23824327
MIRT613345	hsa-miR-19b-2-5p	HITS-CLIP	23824327
MIRT613344	hsa-miR-7850-5p	HITS-CLIP	23824327

Show/Hide all (29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001664	Function	G protein-coupled receptor binding	IBA
GO:0002029	Process	Desensitization of G protein-coupled receptor signaling pathway	IBA
GO:0002029	Process	Desensitization of G protein-coupled receptor signaling pathway	IDA	21799898
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	8427589
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004703	Function	G protein-coupled receptor kinase activity	IBA
GO:0004703	Function	G protein-coupled receptor kinase activity	IDA	21799898
GO:0004703	Function	G protein-coupled receptor kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	23455922, 28514442, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	8427589
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0031623	Process	Receptor internalization	IDA	20074556
GO:0031623	Process	Receptor internalization	IEA
GO:0042995	Component	Cell projection	IEA
GO:0045202	Component	Synapse	IEA
GO:0047696	Function	Beta-adrenergic receptor kinase activity	IEA
GO:0047696	Function	Beta-adrenergic receptor kinase activity	TAS
GO:0098793	Component	Presynapse	IEA
GO:0098794	Component	Postsynapse	IEA

MIM	HGNC	e!Ensembl
109636	290	ENSG00000100077

P35626

Protein name

G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2)

Protein function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00615	RGS	54 → 174	Regulator of G protein signaling domain	Domain
PF00069	Pkinase	191 → 453	Protein kinase domain	Domain
PF00169	PH	559 → 652	PH domain	Domain

Sequence

MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
APKFLNKPRSGTVELPKPSLCHRNSNGL

Sequence length

688

Interactions

View interactions

	KEGG		Reactome
	Chemokine signaling pathway Endocytosis Hedgehog signaling pathway Glutamatergic synapse Olfactory transduction Morphine addiction		G alpha (s) signalling events Cargo recognition for clathrin-mediated endocytosis

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Benign	rs145971750	RCV005902891
Hepatocellular carcinoma	Benign	rs145971750	RCV005902890

Show/Hide Text Mining Associations (17)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alzheimer Disease	Associate	34164834
Bipolar Disorder	Associate	16359584, 19400979, 19766236
Brain Ischemia	Associate	33460396
Camurati Engelmann Syndrome	Stimulate	17125886
Cognition Disorders	Associate	19400979
Glioblastoma	Inhibit	22086906
Hypoxia	Associate	37543278
Mental Disorders	Associate	16359584
Neoplasm Metastasis	Associate	24434559
Neoplasms	Stimulate	24434559
Neuroendocrine Tumors	Associate	37543278
Peritonitis	Stimulate	35996148
Plaque Amyloid	Associate	34164834
Prostatic Neoplasms	Associate	24434559
Prostatic Neoplasms	Stimulate	37543278
Prostatitis	Stimulate	24434559
Stomach Neoplasms	Associate	35996148

GRK3 (G protein-coupled receptor kinase 3)