Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1551
Gene name Gene Name - the full gene name approved by the HGNC.	Cytochrome P450 family 3 subfamily A member 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CYP3A7
Synonyms (NCBI Gene) Gene synonyms aliases	CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, P450HLp2
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which

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miRTarBase ID	miRNA	Experiments
MIRT921557	hsa-miR-103a	CLIP-seq
MIRT921558	hsa-miR-107	CLIP-seq
MIRT921559	hsa-miR-1208	CLIP-seq
MIRT921560	hsa-miR-1255a	CLIP-seq
MIRT921561	hsa-miR-1255b	CLIP-seq
MIRT921562	hsa-miR-1304	CLIP-seq
MIRT921563	hsa-miR-326	CLIP-seq
MIRT921564	hsa-miR-330-5p	CLIP-seq
MIRT921565	hsa-miR-4299	CLIP-seq
MIRT921566	hsa-miR-4456	CLIP-seq
MIRT921567	hsa-miR-4694-5p	CLIP-seq
MIRT921568	hsa-miR-491-3p	CLIP-seq
MIRT921569	hsa-miR-548a-5p	CLIP-seq
MIRT921570	hsa-miR-548ab	CLIP-seq
MIRT921571	hsa-miR-548ak	CLIP-seq
MIRT921572	hsa-miR-548b-5p	CLIP-seq
MIRT921573	hsa-miR-548c-5p	CLIP-seq
MIRT921574	hsa-miR-548d-5p	CLIP-seq
MIRT921575	hsa-miR-548h	CLIP-seq
MIRT921576	hsa-miR-548i	CLIP-seq
MIRT921577	hsa-miR-548j	CLIP-seq
MIRT921578	hsa-miR-548k	CLIP-seq
MIRT921579	hsa-miR-548l	CLIP-seq
MIRT921580	hsa-miR-548q	CLIP-seq
MIRT921581	hsa-miR-548w	CLIP-seq
MIRT921582	hsa-miR-548y	CLIP-seq
MIRT921583	hsa-miR-559	CLIP-seq
MIRT921584	hsa-miR-593	CLIP-seq
MIRT921585	hsa-miR-668	CLIP-seq

Transcription factors

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GO ID	Ontology	Definition	Evidence	Reference
GO:0002933	Process	Lipid hydroxylation	IDA	14559847
GO:0004497	Function	Monooxygenase activity	ISS
GO:0005506	Function	Iron ion binding	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006694	Process	Steroid biosynthetic process	IEA
GO:0006805	Process	Xenobiotic metabolic process	TAS
GO:0008202	Process	Steroid metabolic process	IBA	21873635
GO:0008202	Process	Steroid metabolic process	IDA	14559847
GO:0008210	Process	Estrogen metabolic process	IDA	12865317, 14559847
GO:0008395	Function	Steroid hydroxylase activity	IBA	21873635
GO:0008395	Function	Steroid hydroxylase activity	IDA	14559847
GO:0008401	Function	Retinoic acid 4-hydroxylase activity	IDA	11093772
GO:0019825	Function	Oxygen binding	TAS	2722762
GO:0020037	Function	Heme binding	IEA
GO:0042572	Process	Retinol metabolic process	IEA
GO:0042573	Process	Retinoic acid metabolic process	IDA	11093772
GO:0050649	Function	Testosterone 6-beta-hydroxylase activity	IBA	21873635
GO:0070330	Function	Aromatase activity	IEA
GO:0070989	Process	Oxidative demethylation	IBA	21873635
GO:0101020	Function	Estrogen 16-alpha-hydroxylase activity	IBA	21873635
GO:0101020	Function	Estrogen 16-alpha-hydroxylase activity	IDA	14559847
GO:0101021	Function	Estrogen 2-hydroxylase activity	IDA	12865317

MIM	HGNC	e!Ensembl
605340	2640	ENSG00000160870

	KEGG		Reactome
	Steroid hormone biosynthesis Retinol metabolism Metabolic pathways Chemical carcinogenesis - DNA adducts		Xenobiotics

Disease term	Disease name	References	Source
Unknown
Coronary syndrome	Acute Coronary Syndrome	25935875	ClinVar
Gout	Gout		GWAS

Disease Name	Relationship Type	References
Associations from Text Mining
Adrenal Gland Neoplasms	Associate	18445661
Anencephaly	Associate	15845858
Breast Neoplasms	Associate	26964624, 33495599
Calcinosis Cutis	Inhibit	22971343
Carcinogenesis	Associate	40026294
Carcinoma Hepatocellular	Associate	25024626, 25101946
Carcinoma Renal Cell	Associate	32789468
Colorectal Neoplasms	Associate	23036011
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency	Associate	21915484
Drug Related Side Effects and Adverse Reactions	Associate	26964624
Esophageal Squamous Cell Carcinoma	Associate	23358850
Hypertension	Associate	23036011
Insulin Resistance	Associate	23036011
Laron Syndrome	Associate	33495599
Leukemia Lymphocytic Chronic B Cell	Associate	26964624
Lung Neoplasms	Associate	26964624
Malnutrition	Associate	23036011
Melanosis	Associate	26238215
Neoplasms	Associate	26964624, 40026294
Polycystic Ovary Syndrome	Associate	18445661
Respiratory Distress Syndrome	Associate	22445700
Respiratory Distress Syndrome Newborn	Associate	22445700
Sarcoma Ewing	Associate	25670065
Virilism	Associate	18445661

CYP3A7 (cytochrome P450 family 3 subfamily A member 7)