Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	1544
Gene name Gene Name - the full gene name approved by the HGNC.	Cytochrome P450 family 1 subfamily A member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CYP1A2
Synonyms (NCBI Gene) Gene synonyms aliases	CP12, CYPIA2, P3-450, P450(PA)
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q24.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encode

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miRTarBase ID	miRNA	Experiments	Reference
MIRT052168	hsa-let-7b-5p	CLASH	23622248
MIRT619678	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT619677	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619676	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT619675	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT619674	hsa-miR-8073	HITS-CLIP	23824327
MIRT619673	hsa-miR-1292-3p	HITS-CLIP	23824327
MIRT619672	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT619671	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT619670	hsa-miR-3128	HITS-CLIP	23824327
MIRT619669	hsa-miR-4252	HITS-CLIP	23824327
MIRT619668	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT619667	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT619666	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT619665	hsa-miR-7703	HITS-CLIP	23824327
MIRT619678	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT619677	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT619676	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT619675	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT619674	hsa-miR-8073	HITS-CLIP	23824327
MIRT619673	hsa-miR-1292-3p	HITS-CLIP	23824327
MIRT619672	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT619671	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT619670	hsa-miR-3128	HITS-CLIP	23824327
MIRT619669	hsa-miR-4252	HITS-CLIP	23824327
MIRT619668	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT619667	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT619666	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT619665	hsa-miR-7703	HITS-CLIP	23824327
MIRT920553	hsa-miR-1202	CLIP-seq
MIRT920554	hsa-miR-1228	CLIP-seq
MIRT920555	hsa-miR-1261	CLIP-seq
MIRT920556	hsa-miR-1273f	CLIP-seq
MIRT920557	hsa-miR-1287	CLIP-seq
MIRT920558	hsa-miR-1322	CLIP-seq
MIRT920559	hsa-miR-138	CLIP-seq
MIRT920560	hsa-miR-143	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT920562	hsa-miR-1909	CLIP-seq
MIRT920563	hsa-miR-24	CLIP-seq
MIRT920564	hsa-miR-2909	CLIP-seq
MIRT920565	hsa-miR-3120-5p	CLIP-seq
MIRT920566	hsa-miR-3125	CLIP-seq
MIRT920567	hsa-miR-3165	CLIP-seq
MIRT920568	hsa-miR-3170	CLIP-seq
MIRT920569	hsa-miR-3187-3p	CLIP-seq
MIRT920570	hsa-miR-342-3p	CLIP-seq
MIRT920571	hsa-miR-3613-3p	CLIP-seq
MIRT920572	hsa-miR-3647-3p	CLIP-seq
MIRT920573	hsa-miR-3652	CLIP-seq
MIRT920574	hsa-miR-3664-5p	CLIP-seq
MIRT920575	hsa-miR-3665	CLIP-seq
MIRT920576	hsa-miR-3714	CLIP-seq
MIRT920577	hsa-miR-371-5p	CLIP-seq
MIRT920578	hsa-miR-371b-5p	CLIP-seq
MIRT920579	hsa-miR-3916	CLIP-seq
MIRT920580	hsa-miR-3926	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920582	hsa-miR-3972	CLIP-seq
MIRT920583	hsa-miR-4266	CLIP-seq
MIRT920584	hsa-miR-4267	CLIP-seq
MIRT920585	hsa-miR-4274	CLIP-seq
MIRT920586	hsa-miR-4278	CLIP-seq
MIRT920587	hsa-miR-4284	CLIP-seq
MIRT920588	hsa-miR-4299	CLIP-seq
MIRT920589	hsa-miR-4316	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920591	hsa-miR-4430	CLIP-seq
MIRT920592	hsa-miR-4432	CLIP-seq
MIRT920593	hsa-miR-4433	CLIP-seq
MIRT920594	hsa-miR-4446-3p	CLIP-seq
MIRT920595	hsa-miR-4459	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT920597	hsa-miR-4492	CLIP-seq
MIRT920598	hsa-miR-4498	CLIP-seq
MIRT920599	hsa-miR-4506	CLIP-seq
MIRT920600	hsa-miR-4519	CLIP-seq
MIRT920601	hsa-miR-4522	CLIP-seq
MIRT920602	hsa-miR-4529-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT920604	hsa-miR-4685-5p	CLIP-seq
MIRT920605	hsa-miR-4708-5p	CLIP-seq
MIRT920606	hsa-miR-4710	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT920608	hsa-miR-4736	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT920610	hsa-miR-4764-5p	CLIP-seq
MIRT920611	hsa-miR-4768-3p	CLIP-seq
MIRT920612	hsa-miR-4770	CLIP-seq
MIRT920613	hsa-miR-4792	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT920615	hsa-miR-4799-5p	CLIP-seq
MIRT920616	hsa-miR-499-5p	CLIP-seq
MIRT920617	hsa-miR-548a-3p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT920619	hsa-miR-548e	CLIP-seq
MIRT920620	hsa-miR-548f	CLIP-seq
MIRT920621	hsa-miR-548s	CLIP-seq
MIRT920622	hsa-miR-615-5p	CLIP-seq
MIRT920623	hsa-miR-7	CLIP-seq
MIRT920624	hsa-miR-762	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq
MIRT920556	hsa-miR-1273f	CLIP-seq
MIRT920560	hsa-miR-143	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT1547758	hsa-miR-2467-3p	CLIP-seq
MIRT1547759	hsa-miR-3160-3p	CLIP-seq
MIRT1547760	hsa-miR-3192	CLIP-seq
MIRT1547761	hsa-miR-3612	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT1547764	hsa-miR-4257	CLIP-seq
MIRT1547765	hsa-miR-4487	CLIP-seq
MIRT920605	hsa-miR-4708-5p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT920612	hsa-miR-4770	CLIP-seq
MIRT1547767	hsa-miR-490-3p	CLIP-seq
MIRT1547768	hsa-miR-558	CLIP-seq
MIRT1547769	hsa-miR-650	CLIP-seq
MIRT920553	hsa-miR-1202	CLIP-seq
MIRT920554	hsa-miR-1228	CLIP-seq
MIRT1972786	hsa-miR-1262	CLIP-seq
MIRT920556	hsa-miR-1273f	CLIP-seq
MIRT1972787	hsa-miR-129-5p	CLIP-seq
MIRT920558	hsa-miR-1322	CLIP-seq
MIRT920560	hsa-miR-143	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT1972788	hsa-miR-193a-5p	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT1972790	hsa-miR-2467-5p	CLIP-seq
MIRT1972791	hsa-miR-3122	CLIP-seq
MIRT1972792	hsa-miR-3135b	CLIP-seq
MIRT1972793	hsa-miR-3188	CLIP-seq
MIRT1972794	hsa-miR-3194-5p	CLIP-seq
MIRT1972795	hsa-miR-323-5p	CLIP-seq
MIRT1547761	hsa-miR-3612	CLIP-seq
MIRT1972796	hsa-miR-3616-5p	CLIP-seq
MIRT1972797	hsa-miR-3647-5p	CLIP-seq
MIRT1972798	hsa-miR-365	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT920573	hsa-miR-3652	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT1972800	hsa-miR-3913-5p	CLIP-seq
MIRT920580	hsa-miR-3926	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920582	hsa-miR-3972	CLIP-seq
MIRT1972801	hsa-miR-3975	CLIP-seq
MIRT920588	hsa-miR-4299	CLIP-seq
MIRT1972802	hsa-miR-431	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920591	hsa-miR-4430	CLIP-seq
MIRT920592	hsa-miR-4432	CLIP-seq
MIRT1972803	hsa-miR-4474-5p	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT1972804	hsa-miR-4494	CLIP-seq
MIRT1972805	hsa-miR-4499	CLIP-seq
MIRT1972806	hsa-miR-4649-3p	CLIP-seq
MIRT1972807	hsa-miR-4662a-5p	CLIP-seq
MIRT1972808	hsa-miR-4676-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT1972809	hsa-miR-4701-3p	CLIP-seq
MIRT920605	hsa-miR-4708-5p	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT920611	hsa-miR-4768-3p	CLIP-seq
MIRT920612	hsa-miR-4770	CLIP-seq
MIRT1972810	hsa-miR-4795-5p	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT1547767	hsa-miR-490-3p	CLIP-seq
MIRT920616	hsa-miR-499-5p	CLIP-seq
MIRT1972812	hsa-miR-542-3p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT920621	hsa-miR-548s	CLIP-seq
MIRT1972813	hsa-miR-550a	CLIP-seq
MIRT1972814	hsa-miR-573	CLIP-seq
MIRT1972815	hsa-miR-575	CLIP-seq
MIRT920622	hsa-miR-615-5p	CLIP-seq
MIRT1972816	hsa-miR-636	CLIP-seq
MIRT1547769	hsa-miR-650	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT1972817	hsa-miR-876-3p	CLIP-seq
MIRT1972818	hsa-miR-890	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq
MIRT2208455	hsa-miR-1207-5p	CLIP-seq
MIRT1972786	hsa-miR-1262	CLIP-seq
MIRT920556	hsa-miR-1273f	CLIP-seq
MIRT920558	hsa-miR-1322	CLIP-seq
MIRT920559	hsa-miR-138	CLIP-seq
MIRT2208456	hsa-miR-142-3p	CLIP-seq
MIRT920560	hsa-miR-143	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT920562	hsa-miR-1909	CLIP-seq
MIRT2208457	hsa-miR-2053	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT1547758	hsa-miR-2467-3p	CLIP-seq
MIRT1972790	hsa-miR-2467-5p	CLIP-seq
MIRT1972791	hsa-miR-3122	CLIP-seq
MIRT1972792	hsa-miR-3135b	CLIP-seq
MIRT2208458	hsa-miR-3145-5p	CLIP-seq
MIRT1547759	hsa-miR-3160-3p	CLIP-seq
MIRT920567	hsa-miR-3165	CLIP-seq
MIRT2208459	hsa-miR-3174	CLIP-seq
MIRT1972793	hsa-miR-3188	CLIP-seq
MIRT1547760	hsa-miR-3192	CLIP-seq
MIRT2208460	hsa-miR-3197	CLIP-seq
MIRT1547761	hsa-miR-3612	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT920573	hsa-miR-3652	CLIP-seq
MIRT2208461	hsa-miR-3656	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT1972800	hsa-miR-3913-5p	CLIP-seq
MIRT920580	hsa-miR-3926	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT1972801	hsa-miR-3975	CLIP-seq
MIRT1547764	hsa-miR-4257	CLIP-seq
MIRT920588	hsa-miR-4299	CLIP-seq
MIRT920589	hsa-miR-4316	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920591	hsa-miR-4430	CLIP-seq
MIRT2208462	hsa-miR-4434	CLIP-seq
MIRT1972803	hsa-miR-4474-5p	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT1547765	hsa-miR-4487	CLIP-seq
MIRT1972804	hsa-miR-4494	CLIP-seq
MIRT1972805	hsa-miR-4499	CLIP-seq
MIRT2208463	hsa-miR-4516	CLIP-seq
MIRT2208464	hsa-miR-4531	CLIP-seq
MIRT1972806	hsa-miR-4649-3p	CLIP-seq
MIRT1972809	hsa-miR-4701-3p	CLIP-seq
MIRT920605	hsa-miR-4708-5p	CLIP-seq
MIRT920606	hsa-miR-4710	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT2208465	hsa-miR-4763-3p	CLIP-seq
MIRT920611	hsa-miR-4768-3p	CLIP-seq
MIRT920612	hsa-miR-4770	CLIP-seq
MIRT920613	hsa-miR-4792	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT1547767	hsa-miR-490-3p	CLIP-seq
MIRT1972812	hsa-miR-542-3p	CLIP-seq
MIRT920621	hsa-miR-548s	CLIP-seq
MIRT1972813	hsa-miR-550a	CLIP-seq
MIRT1547768	hsa-miR-558	CLIP-seq
MIRT2208466	hsa-miR-569	CLIP-seq
MIRT920622	hsa-miR-615-5p	CLIP-seq
MIRT1547769	hsa-miR-650	CLIP-seq
MIRT2208467	hsa-miR-658	CLIP-seq
MIRT2208468	hsa-miR-668	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT1972818	hsa-miR-890	CLIP-seq
MIRT2208469	hsa-miR-921	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq
MIRT920554	hsa-miR-1228	CLIP-seq
MIRT920555	hsa-miR-1261	CLIP-seq
MIRT920556	hsa-miR-1273f	CLIP-seq
MIRT920558	hsa-miR-1322	CLIP-seq
MIRT920560	hsa-miR-143	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT2386641	hsa-miR-1915	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT1547758	hsa-miR-2467-3p	CLIP-seq
MIRT1972790	hsa-miR-2467-5p	CLIP-seq
MIRT1972791	hsa-miR-3122	CLIP-seq
MIRT2208458	hsa-miR-3145-5p	CLIP-seq
MIRT1547759	hsa-miR-3160-3p	CLIP-seq
MIRT1972793	hsa-miR-3188	CLIP-seq
MIRT1547760	hsa-miR-3192	CLIP-seq
MIRT1547761	hsa-miR-3612	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT1972800	hsa-miR-3913-5p	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT1972801	hsa-miR-3975	CLIP-seq
MIRT1547764	hsa-miR-4257	CLIP-seq
MIRT920586	hsa-miR-4278	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920593	hsa-miR-4433	CLIP-seq
MIRT920595	hsa-miR-4459	CLIP-seq
MIRT1972803	hsa-miR-4474-5p	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT1547765	hsa-miR-4487	CLIP-seq
MIRT1972806	hsa-miR-4649-3p	CLIP-seq
MIRT920605	hsa-miR-4708-5p	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT2386642	hsa-miR-4726-3p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT2386643	hsa-miR-4747-5p	CLIP-seq
MIRT920611	hsa-miR-4768-3p	CLIP-seq
MIRT920612	hsa-miR-4770	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT1547767	hsa-miR-490-3p	CLIP-seq
MIRT1972813	hsa-miR-550a	CLIP-seq
MIRT1547768	hsa-miR-558	CLIP-seq
MIRT1547769	hsa-miR-650	CLIP-seq
MIRT1972818	hsa-miR-890	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT920565	hsa-miR-3120-5p	CLIP-seq
MIRT2447884	hsa-miR-3150a-5p	CLIP-seq
MIRT2447885	hsa-miR-3150b-5p	CLIP-seq
MIRT1972795	hsa-miR-323-5p	CLIP-seq
MIRT920571	hsa-miR-3613-3p	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT920574	hsa-miR-3664-5p	CLIP-seq
MIRT920577	hsa-miR-371-5p	CLIP-seq
MIRT920578	hsa-miR-371b-5p	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920592	hsa-miR-4432	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT920601	hsa-miR-4522	CLIP-seq
MIRT1972807	hsa-miR-4662a-5p	CLIP-seq
MIRT1972808	hsa-miR-4676-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT1972815	hsa-miR-575	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT1972817	hsa-miR-876-3p	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT1972807	hsa-miR-4662a-5p	CLIP-seq
MIRT1972808	hsa-miR-4676-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT1972815	hsa-miR-575	CLIP-seq
MIRT920554	hsa-miR-1228	CLIP-seq
MIRT2512295	hsa-miR-128	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT2386641	hsa-miR-1915	CLIP-seq
MIRT2208457	hsa-miR-2053	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT920565	hsa-miR-3120-5p	CLIP-seq
MIRT1972791	hsa-miR-3122	CLIP-seq
MIRT2447884	hsa-miR-3150a-5p	CLIP-seq
MIRT2447885	hsa-miR-3150b-5p	CLIP-seq
MIRT920569	hsa-miR-3187-3p	CLIP-seq
MIRT1972795	hsa-miR-323-5p	CLIP-seq
MIRT920571	hsa-miR-3613-3p	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT920574	hsa-miR-3664-5p	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT920577	hsa-miR-371-5p	CLIP-seq
MIRT920578	hsa-miR-371b-5p	CLIP-seq
MIRT1972800	hsa-miR-3913-5p	CLIP-seq
MIRT920580	hsa-miR-3926	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920592	hsa-miR-4432	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT920601	hsa-miR-4522	CLIP-seq
MIRT920602	hsa-miR-4529-5p	CLIP-seq
MIRT1972806	hsa-miR-4649-3p	CLIP-seq
MIRT1972807	hsa-miR-4662a-5p	CLIP-seq
MIRT1972808	hsa-miR-4676-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT2386642	hsa-miR-4726-3p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT2386643	hsa-miR-4747-5p	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT920611	hsa-miR-4768-3p	CLIP-seq
MIRT2512296	hsa-miR-4786-5p	CLIP-seq
MIRT2512297	hsa-miR-4793-5p	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT920616	hsa-miR-499-5p	CLIP-seq
MIRT920617	hsa-miR-548a-3p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT920619	hsa-miR-548e	CLIP-seq
MIRT920620	hsa-miR-548f	CLIP-seq
MIRT920621	hsa-miR-548s	CLIP-seq
MIRT1972813	hsa-miR-550a	CLIP-seq
MIRT2208466	hsa-miR-569	CLIP-seq
MIRT1972815	hsa-miR-575	CLIP-seq
MIRT2512298	hsa-miR-671-5p	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT1972817	hsa-miR-876-3p	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq
MIRT2512295	hsa-miR-128	CLIP-seq
MIRT920561	hsa-miR-1827	CLIP-seq
MIRT2208457	hsa-miR-2053	CLIP-seq
MIRT1972789	hsa-miR-2114	CLIP-seq
MIRT920565	hsa-miR-3120-5p	CLIP-seq
MIRT1972791	hsa-miR-3122	CLIP-seq
MIRT2447884	hsa-miR-3150a-5p	CLIP-seq
MIRT2447885	hsa-miR-3150b-5p	CLIP-seq
MIRT2208460	hsa-miR-3197	CLIP-seq
MIRT1972795	hsa-miR-323-5p	CLIP-seq
MIRT920571	hsa-miR-3613-3p	CLIP-seq
MIRT1972799	hsa-miR-3650	CLIP-seq
MIRT2208461	hsa-miR-3656	CLIP-seq
MIRT920574	hsa-miR-3664-5p	CLIP-seq
MIRT1547762	hsa-miR-3689a-3p	CLIP-seq
MIRT1547763	hsa-miR-3689c	CLIP-seq
MIRT920577	hsa-miR-371-5p	CLIP-seq
MIRT920578	hsa-miR-371b-5p	CLIP-seq
MIRT1972800	hsa-miR-3913-5p	CLIP-seq
MIRT920580	hsa-miR-3926	CLIP-seq
MIRT920581	hsa-miR-3929	CLIP-seq
MIRT920590	hsa-miR-4419b	CLIP-seq
MIRT920592	hsa-miR-4432	CLIP-seq
MIRT920596	hsa-miR-4478	CLIP-seq
MIRT920601	hsa-miR-4522	CLIP-seq
MIRT1972806	hsa-miR-4649-3p	CLIP-seq
MIRT1972807	hsa-miR-4662a-5p	CLIP-seq
MIRT1972808	hsa-miR-4676-5p	CLIP-seq
MIRT920603	hsa-miR-4684-5p	CLIP-seq
MIRT920607	hsa-miR-4722-5p	CLIP-seq
MIRT1547766	hsa-miR-4728-5p	CLIP-seq
MIRT920609	hsa-miR-4755-3p	CLIP-seq
MIRT2512296	hsa-miR-4786-5p	CLIP-seq
MIRT2512297	hsa-miR-4793-5p	CLIP-seq
MIRT920614	hsa-miR-4797-5p	CLIP-seq
MIRT1972811	hsa-miR-485-5p	CLIP-seq
MIRT920616	hsa-miR-499-5p	CLIP-seq
MIRT920617	hsa-miR-548a-3p	CLIP-seq
MIRT920618	hsa-miR-548c-3p	CLIP-seq
MIRT920619	hsa-miR-548e	CLIP-seq
MIRT920620	hsa-miR-548f	CLIP-seq
MIRT920621	hsa-miR-548s	CLIP-seq
MIRT2208466	hsa-miR-569	CLIP-seq
MIRT1972815	hsa-miR-575	CLIP-seq
MIRT920625	hsa-miR-766	CLIP-seq
MIRT1972817	hsa-miR-876-3p	CLIP-seq
MIRT920626	hsa-miR-940	CLIP-seq

Transcription factors

Show/Hide all(4)

Transcription factor	Regulation	Reference
AHR	Unknown	21357676
FOS	Unknown	12135113
HNF1A	Unknown	7723729
JUN	Unknown	12135113

Show/Hide all(70)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004497	Function	Monooxygenase activity	IDA	15327587, 19651758
GO:0004497	Function	Monooxygenase activity	IEA
GO:0004497	Function	Monooxygenase activity	TAS
GO:0005506	Function	Iron ion binding	IEA
GO:0005515	Function	Protein binding	IPI	26988023, 32296183
GO:0005739	Component	Mitochondrion	IBA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006706	Process	Steroid catabolic process	IBA
GO:0006706	Process	Steroid catabolic process	IMP	18356043
GO:0006778	Process	Porphyrin-containing compound metabolic process	IEA
GO:0006805	Process	Xenobiotic metabolic process	IDA	15327587, 19219744
GO:0006805	Process	Xenobiotic metabolic process	IEA
GO:0006805	Process	Xenobiotic metabolic process	TAS
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008210	Process	Estrogen metabolic process	IBA
GO:0008210	Process	Estrogen metabolic process	IDA	11555828, 12865317
GO:0008395	Function	Steroid hydroxylase activity	IBA
GO:0008395	Function	Steroid hydroxylase activity	IEA
GO:0009055	Function	Electron transfer activity	TAS	2813353
GO:0009403	Process	Toxin biosynthetic process	IDA	11511187
GO:0009404	Process	Toxin metabolic process	IBA
GO:0009404	Process	Toxin metabolic process	IEA
GO:0009791	Process	Post-embryonic development	IEA
GO:0009820	Process	Alkaloid metabolic process	IDA	11511187
GO:0010468	Process	Regulation of gene expression	IEA
GO:0016020	Component	Membrane	IEA
GO:0016098	Process	Monoterpenoid metabolic process	IDA	16401082
GO:0016491	Function	Oxidoreductase activity	IDA	16401082, 19219744
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016705	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
GO:0016712	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IBA
GO:0016712	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA
GO:0016712	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IMP	2813353
GO:0016829	Function	Lyase activity	IEA
GO:0018894	Process	Dibenzo-p-dioxin metabolic process	IEA
GO:0019369	Process	Arachidonate metabolic process	IEA
GO:0019373	Process	Epoxygenase P450 pathway	TAS
GO:0019899	Function	Enzyme binding	IPI	15680923
GO:0020037	Function	Heme binding	IDA	17311915
GO:0020037	Function	Heme binding	IEA
GO:0030324	Process	Lung development	IEA
GO:0032259	Process	Methylation	TAS
GO:0032451	Function	Demethylase activity	IDA	2813353
GO:0032787	Process	Monocarboxylic acid metabolic process	IDA	19651758
GO:0034875	Function	Caffeine oxidase activity	IDA	18619574
GO:0042178	Process	Xenobiotic catabolic process	IBA
GO:0042178	Process	Xenobiotic catabolic process	IDA	18619574
GO:0042178	Process	Xenobiotic catabolic process	IMP	18356043
GO:0042445	Process	Hormone metabolic process	IEA
GO:0042572	Process	Retinol metabolic process	IDA	10681376
GO:0042572	Process	Retinol metabolic process	IEA
GO:0042759	Process	Long-chain fatty acid biosynthetic process	TAS
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA	2813353
GO:0045333	Process	Cellular respiration	IEA
GO:0046222	Process	Aflatoxin metabolic process	TAS
GO:0046872	Function	Metal ion binding	IEA
GO:0050665	Process	Hydrogen peroxide biosynthetic process	IEA
GO:0070989	Process	Oxidative demethylation	IDA	18619574
GO:0071276	Process	Cellular response to cadmium ion	IEA
GO:0097267	Process	Omega-hydroxylase P450 pathway	TAS
GO:0101020	Function	Estrogen 16-alpha-hydroxylase activity	IDA	11555828
GO:0101021	Function	Estrogen 2-hydroxylase activity	IDA	11555828, 12865317
GO:0101021	Function	Estrogen 2-hydroxylase activity	IEA
GO:0106256	Function	Hydroperoxy icosatetraenoate dehydratase activity	IEA
GO:0120254	Process	Olefinic compound metabolic process	IEA

MIM	HGNC	e!Ensembl
124060	2596	ENSG00000140505

Protein

UniProt ID

P05177

Protein name

Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)

Protein function

A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins (PubMed:10681376, PubMed:11555828, PubMed:12865317, PubMed:19965576, PubMed:9435160). Mechanistical

PDB

2HI4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00067	p450	42 → 505	Cytochrome P450	Domain

Tissue specificity

TISSUE SPECIFICITY: Liver.

Sequence

MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN
PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG
QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELM
AGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP
ILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN
LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLS
DRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPEL
WEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN

Sequence length

516

Interactions

View interactions

	KEGG		Reactome
	Steroid hormone biosynthesis Caffeine metabolism Tryptophan metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways Chemical carcinogenesis - DNA adducts Chemical carcinogenesis - receptor activation Chemical carcinogenesis - reactive oxygen species		Methylation Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Aflatoxin activation and detoxification Biosynthesis of protectins Biosynthesis of maresin-like SPMs

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Coronary Heart Disease	Coronary heart disease	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS
Lung adenocarcinoma	Lung adenocarcinoma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (64)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenoma	Associate	18751408, 22628494
Adenomatous Polyposis Coli	Associate	7883225
Alzheimer Disease	Associate	36430879
Antley Bixler Syndrome Phenotype	Associate	18455494
Barrett Esophagus	Associate	10933049
Blood Platelet Disorders	Associate	31556777
Breast Neoplasms	Associate	15217502, 15241822, 17295924, 18059023, 18398030, 18813311, 25228414, 25689428, 25921178, 27029552, 28418906, 31477036
Carcinogenesis	Associate	17695473, 18751408
Carcinoma Hepatocellular	Associate	22447115, 26516155, 30971588, 33654112, 38565301, 7524447
Carcinoma Hepatocellular	Inhibit	25024626
Carcinoma Squamous Cell	Associate	22072123
Cerebral Infarction	Associate	33046100
Colorectal Neoplasms	Associate	16800822, 17615053, 17695473, 18751408, 21081473, 23951174
Coronary Disease	Associate	33046100
COVID 19	Associate	34473836
Diabetes Mellitus Type 2	Associate	29439084, 32814585
Drug Related Side Effects and Adverse Reactions	Associate	26331989
Drug Related Side Effects and Adverse Reactions	Inhibit	38036087
Essential Hypertension	Associate	27977510
Fibrosarcoma	Associate	34799689
Fibrosis	Associate	19906068
Fibrosis	Inhibit	25024626
Gout	Associate	29976226
Heart Defects Congenital	Associate	29449662
Hemorrhage	Associate	24762860
Hepatitis B Chronic	Associate	19906068
Hepatolenticular Degeneration	Associate	34117631
HIV Infections	Associate	26348712
Hypertension	Associate	30838377
Hypoglycemia	Associate	31324842
Hypotension Orthostatic	Associate	24555493
Hypoxia	Associate	38287425
Inflammation	Inhibit	32481600
Kidney Diseases	Associate	36701157
Liver Cirrhosis Alcoholic	Inhibit	25024626
Lung Neoplasms	Associate	17477782, 19276377
Migraine Disorders	Associate	20213484
Myocardial Infarction	Associate	30838377
Neoplasms	Associate	10551315, 11501173, 18398030, 19442564, 25719551, 30148168, 31608602, 33654112
Neoplasms	Inhibit	38565301
Neoplasms Squamous Cell	Associate	22072123
Neural Tube Defects	Associate	20641098
Non alcoholic Fatty Liver Disease	Associate	19651758
Pancreatic Neoplasms	Associate	15987714, 18499698
Parkinson Disease	Associate	20304699, 21281405, 29318639
Pediatric Obesity	Associate	27995649
Polyendocrinopathies Autoimmune	Associate	32557834
Porphyria Cutanea Tarda	Associate	20163457, 20957336
Prader Willi Syndrome	Associate	33498922
Precancerous Conditions	Associate	19376845
Prostatic Neoplasms	Associate	29165164
Pulmonary Disease Chronic Obstructive	Associate	20797314
Sleep Disorders Circadian Rhythm	Associate	25059483
Smoke Inhalation Injury	Associate	18499698
Smoke Inhalation Injury	Stimulate	26367336
Spinal Dysraphism	Associate	29681089
Squamous Cell Carcinoma of Head and Neck	Associate	19442564
Stroke	Associate	33046100
Stroke Lacunar	Associate	33046100
Thyroid Diseases	Associate	31608602
Triple Negative Breast Neoplasms	Associate	18398030
Urethral Neoplasms	Associate	14648207
Urinary Bladder Diseases	Associate	21480221
Urinary Bladder Neoplasms	Associate	21480221, 26514519, 27173252, 7786445

CYP1A2 (cytochrome P450 family 1 subfamily A member 2)