Gene Gene information from NCBI Gene database.
Entrez ID 154141
Gene name Membrane bound glycerophospholipid O-acyltransferase 1
Gene symbol MBOAT1
Synonyms (NCBI Gene)
LPEAT1LPLATLPLAT 1LPLAT14LPSATOACT1dJ434O11.1
Chromosome 6
Chromosome location 6p22.3
Summary This gene belongs to the membrane-bound O-acetyltransferase superfamily. The encoded transmembrane protein is an enzyme that transfers organic compounds, preferably from oleoyl-CoA, to hydroxyl groups of protein targets in membranes. A translocation disru
miRNA miRNA information provided by mirtarbase database.
514
miRTarBase ID miRNA Experiments Reference
MIRT636843 hsa-miR-6850-3p HITS-CLIP 23313552
MIRT636842 hsa-miR-6499-5p HITS-CLIP 23313552
MIRT636841 hsa-miR-4284 HITS-CLIP 23313552
MIRT636840 hsa-miR-24-3p HITS-CLIP 23313552
MIRT636839 hsa-miR-3178 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
28
GO ID Ontology Definition Evidence Reference
GO:0003841 Function 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005789 Component Endoplasmic reticulum membrane ISS
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611732 21579 ENSG00000172197
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6ZNC8
Protein name Membrane-bound glycerophospholipid O-acyltransferase 1 (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n
Protein function Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA towards a lysophospholipid producing a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (Pub
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03062 MBOAT 33 439 MBOAT, membrane-bound O-acyltransferase family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in neutrophils. {ECO:0000269|PubMed:18772128}.
Sequence
Sequence length 495
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Glycerolipid metabolism
Glycerophospholipid metabolism
Metabolic pathways
  Acyl chain remodelling of PS
Acyl chain remodelling of PE