Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	154075
Gene name	Sterile alpha motif domain containing 3
Gene symbol	SAMD3
Synonyms (NCBI Gene)	-
Chromosome	6
Chromosome location	6q23.1

Show/Hide all (56)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026352	hsa-miR-192-5p	Microarray	19074876
MIRT1325161	hsa-miR-1273e	CLIP-seq
MIRT1325162	hsa-miR-2964a-3p	CLIP-seq
MIRT1325163	hsa-miR-302f	CLIP-seq
MIRT1325164	hsa-miR-3123	CLIP-seq
MIRT1325165	hsa-miR-3160-3p	CLIP-seq
MIRT1325166	hsa-miR-3189-5p	CLIP-seq
MIRT1325167	hsa-miR-3919	CLIP-seq
MIRT1325168	hsa-miR-4459	CLIP-seq
MIRT1325169	hsa-miR-4487	CLIP-seq
MIRT1325170	hsa-miR-4695-5p	CLIP-seq
MIRT1325171	hsa-miR-4758-3p	CLIP-seq
MIRT1325172	hsa-miR-4760-3p	CLIP-seq
MIRT1325173	hsa-miR-558	CLIP-seq
MIRT1325174	hsa-miR-658	CLIP-seq
MIRT1325175	hsa-miR-665	CLIP-seq
MIRT1325161	hsa-miR-1273e	CLIP-seq
MIRT1325162	hsa-miR-2964a-3p	CLIP-seq
MIRT1325163	hsa-miR-302f	CLIP-seq
MIRT1325164	hsa-miR-3123	CLIP-seq
MIRT1325165	hsa-miR-3160-3p	CLIP-seq
MIRT1325167	hsa-miR-3919	CLIP-seq
MIRT1325168	hsa-miR-4459	CLIP-seq
MIRT1325169	hsa-miR-4487	CLIP-seq
MIRT1325170	hsa-miR-4695-5p	CLIP-seq
MIRT1325173	hsa-miR-558	CLIP-seq
MIRT1325174	hsa-miR-658	CLIP-seq
MIRT1325175	hsa-miR-665	CLIP-seq
MIRT1325161	hsa-miR-1273e	CLIP-seq
MIRT1325162	hsa-miR-2964a-3p	CLIP-seq
MIRT1325163	hsa-miR-302f	CLIP-seq
MIRT1325165	hsa-miR-3160-3p	CLIP-seq
MIRT1325168	hsa-miR-4459	CLIP-seq
MIRT1325169	hsa-miR-4487	CLIP-seq
MIRT1325170	hsa-miR-4695-5p	CLIP-seq
MIRT1325173	hsa-miR-558	CLIP-seq
MIRT1325174	hsa-miR-658	CLIP-seq
MIRT1325175	hsa-miR-665	CLIP-seq
MIRT1325161	hsa-miR-1273e	CLIP-seq
MIRT1325162	hsa-miR-2964a-3p	CLIP-seq
MIRT1325163	hsa-miR-302f	CLIP-seq
MIRT1325164	hsa-miR-3123	CLIP-seq
MIRT1325166	hsa-miR-3189-5p	CLIP-seq
MIRT1325167	hsa-miR-3919	CLIP-seq
MIRT1325168	hsa-miR-4459	CLIP-seq
MIRT1325170	hsa-miR-4695-5p	CLIP-seq
MIRT1325171	hsa-miR-4758-3p	CLIP-seq
MIRT1325175	hsa-miR-665	CLIP-seq
MIRT2616684	hsa-miR-1273g	CLIP-seq
MIRT2616685	hsa-miR-323-3p	CLIP-seq
MIRT2616686	hsa-miR-323b-5p	CLIP-seq
MIRT2616687	hsa-miR-3613-5p	CLIP-seq
MIRT2616684	hsa-miR-1273g	CLIP-seq
MIRT2616685	hsa-miR-323-3p	CLIP-seq
MIRT2616686	hsa-miR-323b-5p	CLIP-seq
MIRT2616687	hsa-miR-3613-5p	CLIP-seq

Show/Hide all (1)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23455924, 25416956, 31515488, 32814053

MIM	HGNC	e!Ensembl
620516	21574	ENSG00000164483

Q8N6K7

Protein name

Sterile alpha motif domain-containing protein 3 (SAM domain-containing protein 3)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00536	SAM_1	2 → 64	SAM domain (Sterile alpha motif)	Domain

Sequence

METWSVEQVCSWLVEKNLGELVHRFQEEEVSGAALLALNDRMVQQLVKKIGHQAVLMDLI
KKYKQNTQGLKSPENPKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENLDNGLI
DQRVLKQRRNVKQILARSKALQWTKSYVLPEFPYDVKCMLAEQKCPDHSMRIRIIEFLQA
DMTKYLEGSLYPSTQQYNDVVNALLQAHPFLDEDGCGFFLWKRALKDRFKYVRRPIEDDE
QVIRNKCKFGHRRGQTRKSLADIRFDEIKLVQIKEEAVCFDSELDEHIKWFQQEYVKTEK
DWREIDKRMSQTLEIRRKMIGSRTPLKDILKLFPFLKCPYQMFREFQLLTRTDIYKKTRH
ILESYSENILTSFSVVDNPINIVLQEKMKHYTDEDMLKYMKMTATCLLLPDVFGDDPSLF
VIMNEQVQVSTPVLEVKNPFNMEVCEFSLYLERERLTKVDDCVTALAALVAAFHVFRIEC
PRRLSQTFNFLETLIFDMHSPYFPSLKEKENEVGFQHPLT

Sequence length

520

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALE REPRODUCTIVE ORGAN CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

SAMD3 (sterile alpha motif domain containing 3)