Gene Gene information from NCBI Gene database.
Entrez ID 154043
Gene name CNKSR family member 3
Gene symbol CNKSR3
Synonyms (NCBI Gene)
CNK3CNK3/IPCEF1MAGI1
Chromosome 6
Chromosome location 6q25.2
miRNA miRNA information provided by mirtarbase database.
464
miRTarBase ID miRNA Experiments Reference
MIRT022563 hsa-miR-124-3p Microarray 18668037
MIRT704529 hsa-miR-3169 HITS-CLIP 23313552
MIRT704528 hsa-miR-518c-5p HITS-CLIP 23313552
MIRT704527 hsa-miR-6764-3p HITS-CLIP 23313552
MIRT704526 hsa-miR-6824-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 22085542, 25416956, 32296183
GO:0005737 Component Cytoplasm IEA
GO:0005886 Component Plasma membrane IEA
GO:0009966 Process Regulation of signal transduction IEA
GO:0010765 Process Positive regulation of sodium ion transport ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
617476 23034 ENSG00000153721
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P9H4
Protein name Connector enhancer of kinase suppressor of ras 3 (Connector enhancer of KSR 3) (CNK homolog protein 3) (CNK3) (CNKSR family member 3) (Maguin-like protein)
Protein function Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly o
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00536 SAM_1 5 69 SAM domain (Sterile alpha motif) Domain
PF10534 CRIC_ras_sig 80 172 Connector enhancer of kinase suppressor of ras Domain
PF00595 PDZ 211 290 PDZ domain Domain
PF06663 DUF1170 332 545 Protein of unknown function (DUF1170) Family
Sequence
Sequence length 555
Interactions View interactions