Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
153830
Gene name Gene Name - the full gene name approved by the HGNC.
Ring finger protein 145
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RNF145
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q33.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020323 hsa-miR-130b-3p Sequencing 20371350
MIRT028157 hsa-miR-93-5p Sequencing 20371350
MIRT031201 hsa-miR-19b-3p Sequencing 20371350
MIRT050999 hsa-miR-17-5p CLASH 23622248
MIRT043418 hsa-miR-331-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0008270 Function Zinc ion binding IEA
GO:0012505 Component Endomembrane system IBA 21873635
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620640 20853 ENSG00000145860
Protein
UniProt ID Q96MT1
Protein name RING finger protein 145 (EC 2.3.2.27)
Protein function E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13705 TRC8_N 8 506 TRC8 N-terminal domain Domain
PF13639 zf-RING_2 535 575 Ring finger domain Domain
Sequence
Sequence length 663
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 25854761
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 37481543
Coronary Disease Associate 33727652
Diabetes Mellitus Associate 33727652
Dyslipidemias Associate 33727652
Hypercholesterolemia Associate 33727652
Hypertension Associate 33727652
Hypoxia Associate 37481543
Hypoxia Brain Stimulate 37481543
Obesity Associate 33727652
Small Cell Lung Carcinoma Associate 37987107