PLEKHG4B (pleckstrin homology and RhoGEF domain containing G4B)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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153478 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Pleckstrin homology and RhoGEF domain containing G4B |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PLEKHG4B |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ARHGEF48 |
Chromosome
Chromosome number
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5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5p15.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a large protein that contains a pleckstrin homology domain and may function as a guanine nucleotide exchange factor. [provided by RefSeq, May 2017] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q96PX9 | ||||||||||
Protein name | Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B) | ||||||||||
Protein function | Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. Plays a role in actin cytoskeletal remodeling in the late stage of cell-cell junction formation by regulating the cont | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 1271 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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