Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	153201
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 36 member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC36A2
Synonyms (NCBI Gene) Gene synonyms aliases	PAT2, TRAMD1
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q33.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene

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SNP ID	Visualize variation	Clinical significance	Consequence
rs77010315	C>A	Uncertain-significance, pathogenic, benign	Coding sequence variant, missense variant, 5 prime UTR variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT694168	hsa-miR-606	HITS-CLIP	23313552
MIRT694167	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT694166	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT694165	hsa-miR-940	HITS-CLIP	23313552
MIRT694164	hsa-miR-3929	HITS-CLIP	23313552
MIRT694163	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694162	hsa-miR-4478	HITS-CLIP	23313552
MIRT694161	hsa-miR-4733-5p	HITS-CLIP	23313552
MIRT694160	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT694159	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT694158	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT694157	hsa-miR-1827	HITS-CLIP	23313552
MIRT694156	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694155	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694154	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT694153	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT694152	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	PAR-CLIP	26701625
MIRT694151	hsa-miR-665	PAR-CLIP	26701625
MIRT694168	hsa-miR-606	HITS-CLIP	23313552
MIRT694167	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT694166	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT694165	hsa-miR-940	HITS-CLIP	23313552
MIRT694164	hsa-miR-3929	HITS-CLIP	23313552
MIRT694163	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694162	hsa-miR-4478	HITS-CLIP	23313552
MIRT694161	hsa-miR-4733-5p	HITS-CLIP	23313552
MIRT694160	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT694159	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT694158	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT694157	hsa-miR-1827	HITS-CLIP	23313552
MIRT694156	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694155	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694154	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT694153	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT694152	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	HITS-CLIP	23313552
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT1361988	hsa-miR-1227	CLIP-seq
MIRT1361989	hsa-miR-1268	CLIP-seq
MIRT1361990	hsa-miR-1268b	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361994	hsa-miR-19a	CLIP-seq
MIRT1361995	hsa-miR-19b	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362000	hsa-miR-224	CLIP-seq
MIRT1362001	hsa-miR-23a	CLIP-seq
MIRT1362002	hsa-miR-23b	CLIP-seq
MIRT1362003	hsa-miR-23c	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362006	hsa-miR-28-5p	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362010	hsa-miR-3126-3p	CLIP-seq
MIRT1362011	hsa-miR-3139	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT1362014	hsa-miR-3175	CLIP-seq
MIRT1362015	hsa-miR-3176	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362023	hsa-miR-3665	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362032	hsa-miR-3922-3p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362037	hsa-miR-4435	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362039	hsa-miR-4486	CLIP-seq
MIRT1362040	hsa-miR-4505	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT1362043	hsa-miR-4651	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT1362049	hsa-miR-518a-5p	CLIP-seq
MIRT1362050	hsa-miR-527	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT1362053	hsa-miR-585	CLIP-seq
MIRT1362054	hsa-miR-608	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362058	hsa-miR-708	CLIP-seq
MIRT1362059	hsa-miR-764	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT1361988	hsa-miR-1227	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361989	hsa-miR-1268	CLIP-seq
MIRT1361990	hsa-miR-1268b	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT2331338	hsa-miR-3121-5p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT1362014	hsa-miR-3175	CLIP-seq
MIRT2331339	hsa-miR-3187-3p	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT2331342	hsa-miR-4433	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362037	hsa-miR-4435	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362039	hsa-miR-4486	CLIP-seq
MIRT1362040	hsa-miR-4505	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT2331344	hsa-miR-4701-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT2331345	hsa-miR-500a	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT2331346	hsa-miR-548s	CLIP-seq
MIRT1362053	hsa-miR-585	CLIP-seq
MIRT2331347	hsa-miR-588	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362043	hsa-miR-4651	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362054	hsa-miR-608	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2459729	hsa-miR-4311	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT2625814	hsa-miR-3675-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2625815	hsa-miR-3926	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT2625816	hsa-miR-4786-5p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT2625817	hsa-miR-548aa	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2331346	hsa-miR-548s	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT2625818	hsa-miR-769-5p	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq

Show/Hide all(37)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005280	Function	Amino acid:proton symporter activity	IBA
GO:0005280	Function	Amino acid:proton symporter activity	IDA	12809675, 19033659
GO:0005280	Function	Amino acid:proton symporter activity	IEA
GO:0005280	Function	Amino acid:proton symporter activity	ISS
GO:0005297	Function	Proline:proton symporter activity	IDA	12809675, 19033659
GO:0005297	Function	Proline:proton symporter activity	IEA
GO:0005768	Component	Endosome	IEA
GO:0005774	Component	Vacuolar membrane	IBA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	ISS
GO:0005886	Component	Plasma membrane	IDA	19033659
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	TAS
GO:0006865	Process	Amino acid transport	IEA
GO:0006865	Process	Amino acid transport	TAS
GO:0015171	Function	Amino acid transmembrane transporter activity	TAS
GO:0015180	Function	L-alanine transmembrane transporter activity	IBA
GO:0015180	Function	L-alanine transmembrane transporter activity	IEA
GO:0015187	Function	Glycine transmembrane transporter activity	IBA
GO:0015187	Function	Glycine transmembrane transporter activity	IEA
GO:0015193	Function	L-proline transmembrane transporter activity	IBA
GO:0015193	Function	L-proline transmembrane transporter activity	IEA
GO:0015808	Process	L-alanine transport	IBA
GO:0015808	Process	L-alanine transport	IEA
GO:0015816	Process	Glycine transport	IBA
GO:0015816	Process	Glycine transport	IEA
GO:0015824	Process	Proline transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0035524	Process	Proline transmembrane transport	IBA
GO:0035524	Process	Proline transmembrane transport	IMP	19033659
GO:0055038	Component	Recycling endosome membrane	IEA
GO:0055038	Component	Recycling endosome membrane	ISS
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1902600	Process	Proton transmembrane transport	IBA
GO:1902600	Process	Proton transmembrane transport	IEA

MIM	HGNC	e!Ensembl
608331	18762	ENSG00000186335

Protein

UniProt ID

Q495M3

Protein name

Proton-coupled amino acid transporter 2 (Proton/amino acid transporter 2) (Solute carrier family 36 member 2) (Transmembrane domain rich protein 1) (Tramdorin-1)

Protein function

Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported. Extension of the backbone length, as in beta-alanine and 4-amin

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01490	Aa_trans	52 → 463	Transmembrane amino acid transporter protein	Family

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus. {ECO:0000269|PubMed:15058382, ECO:0000269|PubMed:19033659}.

Sequence

MSVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDSTFLDESPSESAGLKKTKGITVFQAL
IHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPF
MDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAV
NSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLV
IIIQYITQEIPDPSRLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFPAILS
LGMSIVTSLYIGMAALGYLRFGDDIKASISLNLPNCWLYQSVKLLYIAGILCTYALQFYV
PAEIIIPFAISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALAL
IIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTT
FVR

Sequence length

483

Interactions

View interactions

	KEGG		Reactome
	Protein digestion and absorption		Amino acid transport across the plasma membrane Proton-coupled neutral amino acid transporters Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG)

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
hyperglycinuria	Hyperglycinuria	N/A	N/A	ClinVar
Iminoglycinuria	iminoglycinuria	N/A	N/A	GenCC
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
2 Methylbutyryl CoA Dehydrogenase Deficiency	Associate	35236679
Cerebral Infarction	Associate	26352407
Iminoglycinuria	Associate	19033659
Neoplasm Metastasis	Associate	35936004
Neoplasms	Associate	35936004

SLC36A2 (solute carrier family 36 member 2)