Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	153201
Gene name Gene Name - the full gene name approved by the HGNC.	Solute carrier family 36 member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SLC36A2
Synonyms (NCBI Gene) Gene synonyms aliases	PAT2, TRAMD1
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q33.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene

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SNP ID	Visualize variation	Clinical significance	Consequence
rs77010315	C>A	Uncertain-significance, pathogenic, benign	Coding sequence variant, missense variant, 5 prime UTR variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT694168	hsa-miR-606	HITS-CLIP	23313552
MIRT694167	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT694166	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT694165	hsa-miR-940	HITS-CLIP	23313552
MIRT694164	hsa-miR-3929	HITS-CLIP	23313552
MIRT694163	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694162	hsa-miR-4478	HITS-CLIP	23313552
MIRT694161	hsa-miR-4733-5p	HITS-CLIP	23313552
MIRT694160	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT694159	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT694158	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT694157	hsa-miR-1827	HITS-CLIP	23313552
MIRT694156	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694155	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694154	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT694153	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT694152	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	PAR-CLIP	26701625
MIRT694151	hsa-miR-665	PAR-CLIP	26701625
MIRT694168	hsa-miR-606	HITS-CLIP	23313552
MIRT694167	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT694166	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT694165	hsa-miR-940	HITS-CLIP	23313552
MIRT694164	hsa-miR-3929	HITS-CLIP	23313552
MIRT694163	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694162	hsa-miR-4478	HITS-CLIP	23313552
MIRT694161	hsa-miR-4733-5p	HITS-CLIP	23313552
MIRT694160	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT694159	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT694158	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT694157	hsa-miR-1827	HITS-CLIP	23313552
MIRT694156	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694155	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694154	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT694153	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT694152	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT694151	hsa-miR-665	HITS-CLIP	23313552
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT1361988	hsa-miR-1227	CLIP-seq
MIRT1361989	hsa-miR-1268	CLIP-seq
MIRT1361990	hsa-miR-1268b	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361994	hsa-miR-19a	CLIP-seq
MIRT1361995	hsa-miR-19b	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362000	hsa-miR-224	CLIP-seq
MIRT1362001	hsa-miR-23a	CLIP-seq
MIRT1362002	hsa-miR-23b	CLIP-seq
MIRT1362003	hsa-miR-23c	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362006	hsa-miR-28-5p	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362010	hsa-miR-3126-3p	CLIP-seq
MIRT1362011	hsa-miR-3139	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT1362014	hsa-miR-3175	CLIP-seq
MIRT1362015	hsa-miR-3176	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362023	hsa-miR-3665	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362032	hsa-miR-3922-3p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362037	hsa-miR-4435	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362039	hsa-miR-4486	CLIP-seq
MIRT1362040	hsa-miR-4505	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT1362043	hsa-miR-4651	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT1362049	hsa-miR-518a-5p	CLIP-seq
MIRT1362050	hsa-miR-527	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT1362053	hsa-miR-585	CLIP-seq
MIRT1362054	hsa-miR-608	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362058	hsa-miR-708	CLIP-seq
MIRT1362059	hsa-miR-764	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT1361988	hsa-miR-1227	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361989	hsa-miR-1268	CLIP-seq
MIRT1361990	hsa-miR-1268b	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1362004	hsa-miR-24	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT2331338	hsa-miR-3121-5p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT1362014	hsa-miR-3175	CLIP-seq
MIRT2331339	hsa-miR-3187-3p	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362018	hsa-miR-342-3p	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362033	hsa-miR-4284	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT2331342	hsa-miR-4433	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362037	hsa-miR-4435	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362039	hsa-miR-4486	CLIP-seq
MIRT1362040	hsa-miR-4505	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT2331344	hsa-miR-4701-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT2331345	hsa-miR-500a	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT1362051	hsa-miR-544b	CLIP-seq
MIRT2331346	hsa-miR-548s	CLIP-seq
MIRT1362053	hsa-miR-585	CLIP-seq
MIRT2331347	hsa-miR-588	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT1362061	hsa-miR-890	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361987	hsa-miR-1	CLIP-seq
MIRT2107234	hsa-miR-1261	CLIP-seq
MIRT1361992	hsa-miR-1293	CLIP-seq
MIRT1361993	hsa-miR-142-3p	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361997	hsa-miR-206	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362012	hsa-miR-3153	CLIP-seq
MIRT1362013	hsa-miR-3165	CLIP-seq
MIRT2107235	hsa-miR-3170	CLIP-seq
MIRT2107236	hsa-miR-3201	CLIP-seq
MIRT1362020	hsa-miR-3622a-3p	CLIP-seq
MIRT1362021	hsa-miR-3622b-3p	CLIP-seq
MIRT1362025	hsa-miR-3673	CLIP-seq
MIRT1362026	hsa-miR-3681	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT1362038	hsa-miR-4483	CLIP-seq
MIRT1362043	hsa-miR-4651	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT2107237	hsa-miR-4791	CLIP-seq
MIRT1362054	hsa-miR-608	CLIP-seq
MIRT1362056	hsa-miR-613	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2459729	hsa-miR-4311	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1361991	hsa-miR-1285	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362005	hsa-miR-25	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT1362016	hsa-miR-3187-5p	CLIP-seq
MIRT1362017	hsa-miR-32	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362022	hsa-miR-363	CLIP-seq
MIRT1362024	hsa-miR-367	CLIP-seq
MIRT2625814	hsa-miR-3675-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2625815	hsa-miR-3926	CLIP-seq
MIRT1362034	hsa-miR-4293	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362035	hsa-miR-4325	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT2625816	hsa-miR-4786-5p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362048	hsa-miR-508-5p	CLIP-seq
MIRT2625817	hsa-miR-548aa	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2331346	hsa-miR-548s	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq
MIRT1362055	hsa-miR-612	CLIP-seq
MIRT1362057	hsa-miR-661	CLIP-seq
MIRT1362060	hsa-miR-766	CLIP-seq
MIRT2625818	hsa-miR-769-5p	CLIP-seq
MIRT1362062	hsa-miR-92a	CLIP-seq
MIRT1362063	hsa-miR-92b	CLIP-seq
MIRT1361996	hsa-miR-2054	CLIP-seq
MIRT1361998	hsa-miR-216a	CLIP-seq
MIRT1361999	hsa-miR-216b	CLIP-seq
MIRT1362007	hsa-miR-298	CLIP-seq
MIRT1362008	hsa-miR-3065-3p	CLIP-seq
MIRT1362009	hsa-miR-3122	CLIP-seq
MIRT2331340	hsa-miR-338-3p	CLIP-seq
MIRT1362019	hsa-miR-3613-3p	CLIP-seq
MIRT1362027	hsa-miR-3689a-3p	CLIP-seq
MIRT1362028	hsa-miR-3689c	CLIP-seq
MIRT1362029	hsa-miR-371-5p	CLIP-seq
MIRT1362030	hsa-miR-371b-5p	CLIP-seq
MIRT1362031	hsa-miR-3913-5p	CLIP-seq
MIRT2331341	hsa-miR-4310	CLIP-seq
MIRT1362036	hsa-miR-4434	CLIP-seq
MIRT1362041	hsa-miR-4516	CLIP-seq
MIRT1362042	hsa-miR-4531	CLIP-seq
MIRT2459730	hsa-miR-4662a-5p	CLIP-seq
MIRT2459731	hsa-miR-4676-5p	CLIP-seq
MIRT2331343	hsa-miR-4679	CLIP-seq
MIRT1362044	hsa-miR-4684-5p	CLIP-seq
MIRT1362045	hsa-miR-4728-5p	CLIP-seq
MIRT1362046	hsa-miR-4755-3p	CLIP-seq
MIRT1362047	hsa-miR-4802-3p	CLIP-seq
MIRT1362052	hsa-miR-548c-3p	CLIP-seq
MIRT2459732	hsa-miR-575	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003333	Process	Amino acid transmembrane transport	IBA	21873635
GO:0005280	Function	Amino acid:proton symporter activity	IBA	21873635
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Ion transport	TAS
GO:0006865	Process	Amino acid transport	TAS
GO:0015171	Function	Amino acid transmembrane transporter activity	IBA	21873635
GO:0015171	Function	Amino acid transmembrane transporter activity	TAS
GO:0015180	Function	L-alanine transmembrane transporter activity	IBA	21873635
GO:0015187	Function	Glycine transmembrane transporter activity	IBA	21873635
GO:0015187	Function	Glycine transmembrane transporter activity	IMP	19033659
GO:0015193	Function	L-proline transmembrane transporter activity	IBA	21873635
GO:0015808	Process	L-alanine transport	IBA	21873635
GO:0015816	Process	Glycine transport	IBA	21873635
GO:0015824	Process	Proline transport	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0035524	Process	Proline transmembrane transport	IBA	21873635
GO:0035524	Process	Proline transmembrane transport	IMP	19033659
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1902600	Process	Proton transmembrane transport	IBA	21873635

MIM	HGNC	e!Ensembl
608331	18762	ENSG00000186335

Protein

UniProt ID

Q495M3

Protein name

Proton-coupled amino acid transporter 2 (Proton/amino acid transporter 2) (Solute carrier family 36 member 2) (Transmembrane domain rich protein 1) (Tramdorin-1)

Protein function

Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported. Extension of the backbone length, as in beta-alanine and 4-amin

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01490	Aa_trans	52 → 463	Transmembrane amino acid transporter protein	Family

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus. {ECO:0000269|PubMed:15058382, ECO:0000269|PubMed:19033659}.

Sequence

MSVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDSTFLDESPSESAGLKKTKGITVFQAL
IHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPF
MDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAV
NSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLV
IIIQYITQEIPDPSRLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFPAILS
LGMSIVTSLYIGMAALGYLRFGDDIKASISLNLPNCWLYQSVKLLYIAGILCTYALQFYV
PAEIIIPFAISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALAL
IIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTT
FVR

Sequence length

483

Interactions

View interactions

	KEGG		Reactome
	Protein digestion and absorption		Amino acid transport across the plasma membrane Proton-coupled neutral amino acid transporters Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG)

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID
Causal
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)
Nephronophthisis	NEPHROLITHIASIS, CALCIUM OXALATE	rs62635288, rs267607116, rs201893408, rs267607117, rs202149403, rs118204032, rs121918244, rs750962965, rs1474058708, rs119456959, rs119456960, rs119456961, rs119456962, rs267606916, rs137852856 View all (190 more)

Show/Hide Unknown Diseases (3)

Disease term	Disease name	References	Source
Unknown
Hyperglycinuria	HYPERGLYCINURIA (disorder)	19033659	ClinVar
Iminoglycinuria	iminoglycinuria		GenCC
Oligodendroglioma	Oligodendroglioma		GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining
2 Methylbutyryl CoA Dehydrogenase Deficiency	Associate	35236679
Cerebral Infarction	Associate	26352407
Iminoglycinuria	Associate	19033659
Neoplasm Metastasis	Associate	35936004
Neoplasms	Associate	35936004

SLC36A2 (solute carrier family 36 member 2)