Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
153129
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 38 member 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC38A9
Synonyms (NCBI Gene) Gene synonyms aliases
SNAT9, URLC11
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q11.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT671509 hsa-miR-5197-5p HITS-CLIP 23824327
MIRT671508 hsa-miR-130a-3p HITS-CLIP 23824327
MIRT671507 hsa-miR-130b-3p HITS-CLIP 23824327
MIRT671506 hsa-miR-301a-3p HITS-CLIP 23824327
MIRT671505 hsa-miR-301b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003333 Process Amino acid transmembrane transport IBA
GO:0003333 Process Amino acid transmembrane transport IDA 25567906, 29053970
GO:0005085 Function Guanyl-nucleotide exchange factor activity IDA 30181260
GO:0005515 Function Protein binding IPI 25561175, 25567906, 28336668, 30956113, 32433612, 33961781
GO:0005764 Component Lysosome IDA 25561175, 25567906
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616203 26907 ENSG00000177058
Protein
UniProt ID Q8NBW4
Protein name Neutral amino acid transporter 9 (Solute carrier family 38 member 9) (Up-regulated in lung cancer 11)
Protein function Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels (PubMed:25561175, PubMed:25567906, PubMed:29053970). Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 compl
PDB 6WJ2 , 6WJ3 , 8DHB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01490 Aa_trans 115 254 Transmembrane amino acid transporter protein Family
PF01490 Aa_trans 271 561 Transmembrane amino acid transporter protein Family
Sequence
Sequence length 561
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  mTOR signaling pathway   Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription
Amino acids regulate mTORC1
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Alzheimer disease Alzheimer's disease or family history of Alzheimer's disease N/A N/A GWAS
Diabetes Type 2 diabetes N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Colorectal Neoplasms Associate 27609023
Diabetes Mellitus Type 2 Associate 36364703
Diabetic Angiopathies Associate 36364703
Inflammatory Bowel Diseases Associate 24762746
Renal Insufficiency Chronic Associate 36364703