SPMIP2 (sperm microtubule inner protein 2)

Gene

• Entrez ID: 152940
• Gene name: Sperm microtubule inner protein 2
• Gene symbol: SPMIP2
• Synonyms (NCBI Gene): C4orf45
• Chromosome: 4
• Chromosome location: 4q32.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017095	hsa-miR-335-5p	Microarray	18185580
MIRT1951722	hsa-miR-199a-3p	CLIP-seq
MIRT1951723	hsa-miR-199b-3p	CLIP-seq
MIRT1951724	hsa-miR-3129-5p	CLIP-seq
MIRT2189602	hsa-miR-1237	CLIP-seq
MIRT2189603	hsa-miR-1248	CLIP-seq
MIRT2189604	hsa-miR-4279	CLIP-seq
MIRT2189605	hsa-miR-4799-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96LM5
• Protein name: Protein SPMIP2 (Sperm-associated microtubule inner protein 2)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15123	DUF4562	19 → 133	Domain of unknown function (DUF4562)	Family

• Sequence:

  MASVSYQKPTSTTVGKQMIFTGPDYIKDYLPKIHQHTSYVGEQHLALEKTGDLRYLWRPA
  SNRSLPAKYKHEYVSEIGWRIPQYNFINKSRLGSGFHIKYEELSQASLDSITHRYQNPWQ
  PKPHVLDMQGKQSRASFAWHMSAFEDTDQRNSKWAILVRQCKSSLPRASKPPKLPKLPKK
  EKKRKH

• Sequence length: 186

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SYSTEMIC MASTOCYTOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations