Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	152877
Gene name Gene Name - the full gene name approved by the HGNC.	Family with sequence similarity 53 member A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FAM53A
Synonyms (NCBI Gene) Gene synonyms aliases	DNTNP
Chromosome Chromosome number	4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	4p16.3

Show/Hide all(33)

miRTarBase ID	miRNA	Experiments
MIRT985634	hsa-miR-1915	CLIP-seq
MIRT985635	hsa-miR-3148	CLIP-seq
MIRT985636	hsa-miR-3665	CLIP-seq
MIRT985637	hsa-miR-4436b-3p	CLIP-seq
MIRT985638	hsa-miR-4496	CLIP-seq
MIRT985639	hsa-miR-4529-5p	CLIP-seq
MIRT985640	hsa-miR-4685-5p	CLIP-seq
MIRT985641	hsa-miR-4698	CLIP-seq
MIRT985642	hsa-miR-4715-3p	CLIP-seq
MIRT985643	hsa-miR-4736	CLIP-seq
MIRT985644	hsa-miR-4753-5p	CLIP-seq
MIRT985645	hsa-miR-548a-3p	CLIP-seq
MIRT985646	hsa-miR-548ae	CLIP-seq
MIRT985647	hsa-miR-548aj	CLIP-seq
MIRT985648	hsa-miR-548am	CLIP-seq
MIRT985649	hsa-miR-548e	CLIP-seq
MIRT985650	hsa-miR-548f	CLIP-seq
MIRT985651	hsa-miR-548x	CLIP-seq
MIRT985652	hsa-miR-651	CLIP-seq
MIRT985653	hsa-miR-764	CLIP-seq
MIRT985654	hsa-miR-885-3p	CLIP-seq
MIRT985655	hsa-miR-4728-5p	CLIP-seq
MIRT985656	hsa-miR-602	CLIP-seq
MIRT2449366	hsa-miR-146b-3p	CLIP-seq
MIRT2449367	hsa-miR-3173-5p	CLIP-seq
MIRT2449368	hsa-miR-3664-5p	CLIP-seq
MIRT985636	hsa-miR-3665	CLIP-seq
MIRT2449369	hsa-miR-4292	CLIP-seq
MIRT2449370	hsa-miR-4532	CLIP-seq
MIRT2449371	hsa-miR-4714-5p	CLIP-seq
MIRT985643	hsa-miR-4736	CLIP-seq
MIRT2449372	hsa-miR-486-3p	CLIP-seq
MIRT2449373	hsa-miR-874	CLIP-seq

Show/Hide all(3)

GO ID	Ontology	Definition	Evidence
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006606	Process	Protein import into nucleus	IBA

MIM	HGNC	e!Ensembl
617229	31860	ENSG00000174137

Protein

UniProt ID

Q6NSI3

Protein name

Protein FAM53A (Dorsal neural-tube nuclear protein)

Protein function

May play an important role in neural development; the dorsomedial roof of the third ventricle.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15242	FAM53	1 → 294	Family of FAM53	Family

Sequence

MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVR
SQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRH
CRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPT
SPATPRPSSASGGFVDSSEGSAGSGPLWCSAESCLPSTRRRPSLSQERLAGAGTPLPWAS
SSPTSTPALGGRRGLLRCRSQPCVLSGKRSRRKRRREEDARWTRPSLDFLKMTQTLKNSK
SLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLRTSPVHPNLWASRESVT
SDGSRRSSGDPRDGDSVGEEGVFPRARWELDLEQIENN

Sequence length

398

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	28179588
Osteoarthritis	Associate	37579195

FAM53A (family with sequence similarity 53 member A)