Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
152519
Gene name Gene Name - the full gene name approved by the HGNC.
NIPA like domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NIPAL1
Synonyms (NCBI Gene) Gene synonyms aliases
NIPA3, NPAL1, SLC57A3
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4p12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT026452 hsa-miR-192-5p Microarray 19074876
MIRT043429 hsa-miR-331-3p CLASH 23622248
MIRT667216 hsa-miR-6890-3p HITS-CLIP 23824327
MIRT667215 hsa-miR-6887-3p HITS-CLIP 23824327
MIRT667214 hsa-miR-4667-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0015095 Function Magnesium ion transmembrane transporter activity IEA
GO:0015693 Process Magnesium ion transport IBA 21873635
GO:0016020 Component Membrane IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:1903830 Process Magnesium ion transmembrane transport IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620340 27194 ENSG00000163293
Protein
UniProt ID Q6NVV3
Protein name Magnesium transporter NIPA3 (NIPA-like protein 1) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 3)
Protein function Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05653 Mg_trans_NIPA 66 360 Magnesium transporter NIPA Family
Tissue specificity TISSUE SPECIFICITY: Expressed in the pancreatic islets. {ECO:0000269|PubMed:32439805}.
Sequence
Sequence length 410
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Miscellaneous transport and binding events
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Cone-rod dystrophy Cone-Rod Dystrophies rs200691042, rs121908281, rs28940314, rs121434337, rs80338903, rs121909398, rs28937883, rs397515360, rs137853006, rs786205085, rs137853040, rs137853041, rs786205086, rs104894671, rs1568626209
View all (207 more)
30718709
Macular dystrophy Macular dystrophy rs80338903, rs267606875, rs137853006, rs62635654, rs104893967, rs61755793, rs62625014, rs724159985, rs398122391, rs1800728, rs61755810, rs61755814, rs61748556, rs61751263, rs61751402
View all (42 more)
30718709
Retinal dystrophy Retinal Dystrophies rs267606794, rs200691042, rs397704718, rs202193201, rs794728002, rs121965036, rs121965057, rs121918129, rs137853190, rs386834252, rs121918165, rs137853113, rs137853114, rs121918328, rs587777803
View all (2328 more)
Retinitis pigmentosa Retinitis Pigmentosa, RETINITIS PIGMENTOSA 49 rs267606794, rs200691042, rs397704718, rs202193201, rs267606793, rs2147483647, rs779886453, rs267606691, rs794728002, rs878853253, rs137853189, rs137853190, rs137853112, rs137853113, rs137853114
View all (1830 more)
24265693, 7479749, 30718709, 26306921, 25611614, 28981474, 23462753, 25268133
Unknown
Disease term Disease name Evidence References Source
Asthma Childhood asthma 23829686 ClinVar
Gout Gout GWAS
Uterine Fibroids Uterine Fibroids GWAS
Breast Cancer Breast Cancer Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Nasopharyngeal Carcinoma Associate 31289279