Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	152518
Gene name	Nuclear transcription factor, X-box binding like 1
Gene symbol	NFXL1
Synonyms (NCBI Gene)	CDZFPHOZFPOZFPURCC5
Chromosome	4
Chromosome location	4p12

Show/Hide all (57)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038003	hsa-miR-500a-5p	CLASH	23622248
MIRT1183654	hsa-miR-1303	CLIP-seq
MIRT1183655	hsa-miR-132	CLIP-seq
MIRT1183656	hsa-miR-143	CLIP-seq
MIRT1183657	hsa-miR-146b-3p	CLIP-seq
MIRT1183658	hsa-miR-212	CLIP-seq
MIRT1183659	hsa-miR-3065-3p	CLIP-seq
MIRT1183660	hsa-miR-3123	CLIP-seq
MIRT1183661	hsa-miR-3145-3p	CLIP-seq
MIRT1183662	hsa-miR-3173-3p	CLIP-seq
MIRT1183663	hsa-miR-34b	CLIP-seq
MIRT1183664	hsa-miR-3658	CLIP-seq
MIRT1183665	hsa-miR-3684	CLIP-seq
MIRT1183666	hsa-miR-376c	CLIP-seq
MIRT1183667	hsa-miR-3920	CLIP-seq
MIRT1183668	hsa-miR-3925-5p	CLIP-seq
MIRT1183669	hsa-miR-4428	CLIP-seq
MIRT1183670	hsa-miR-4495	CLIP-seq
MIRT1183671	hsa-miR-4511	CLIP-seq
MIRT1183672	hsa-miR-4536	CLIP-seq
MIRT1183673	hsa-miR-4684-5p	CLIP-seq
MIRT1183674	hsa-miR-4756-3p	CLIP-seq
MIRT1183675	hsa-miR-4768-5p	CLIP-seq
MIRT1183676	hsa-miR-4770	CLIP-seq
MIRT1183677	hsa-miR-4797-5p	CLIP-seq
MIRT1183678	hsa-miR-548ag	CLIP-seq
MIRT1183679	hsa-miR-548ai	CLIP-seq
MIRT1183680	hsa-miR-548b-3p	CLIP-seq
MIRT2053255	hsa-miR-135a	CLIP-seq
MIRT2053256	hsa-miR-135b	CLIP-seq
MIRT2053257	hsa-miR-217	CLIP-seq
MIRT2053258	hsa-miR-24	CLIP-seq
MIRT2053259	hsa-miR-3158-5p	CLIP-seq
MIRT2053260	hsa-miR-4264	CLIP-seq
MIRT2053261	hsa-miR-4284	CLIP-seq
MIRT2053262	hsa-miR-4418	CLIP-seq
MIRT2053263	hsa-miR-4427	CLIP-seq
MIRT2053264	hsa-miR-4680-3p	CLIP-seq
MIRT2053265	hsa-miR-509-3-5p	CLIP-seq
MIRT2053266	hsa-miR-509-5p	CLIP-seq
MIRT2053267	hsa-miR-622	CLIP-seq
MIRT2053268	hsa-miR-944	CLIP-seq
MIRT2053255	hsa-miR-135a	CLIP-seq
MIRT2053256	hsa-miR-135b	CLIP-seq
MIRT2053257	hsa-miR-217	CLIP-seq
MIRT2053259	hsa-miR-3158-5p	CLIP-seq
MIRT2053262	hsa-miR-4418	CLIP-seq
MIRT2282567	hsa-miR-4753-3p	CLIP-seq
MIRT1183675	hsa-miR-4768-5p	CLIP-seq
MIRT2053265	hsa-miR-509-3-5p	CLIP-seq
MIRT2053266	hsa-miR-509-5p	CLIP-seq
MIRT2282568	hsa-miR-550b	CLIP-seq
MIRT1183654	hsa-miR-1303	CLIP-seq
MIRT1183660	hsa-miR-3123	CLIP-seq
MIRT1183663	hsa-miR-34b	CLIP-seq
MIRT1183664	hsa-miR-3658	CLIP-seq
MIRT1183668	hsa-miR-3925-5p	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
620488	18726	ENSG00000170448

Q6ZNB6

Protein name

NF-X1-type zinc finger protein NFXL1 (Ovarian zinc finger protein) (hOZFP)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01422	zf-NF-X1	265 → 282	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	318 → 336	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	371 → 389	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	424 → 442	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	476 → 494	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	497 → 521	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	567 → 579	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	589 → 601	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	664 → 681	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	712 → 730	NF-X1 type zinc finger	Family
PF01422	zf-NF-X1	775 → 793	NF-X1 type zinc finger	Family

Sequence

MEASWRQVAGGRGRSRGRATAAPSGNGVHLRGAGGGREKGSVGAVPSGTSPGGVATTAAA
GSRHSPAGSQALQTTAASELMSQKKFEEIKKANQAAARKLVEEQFSSSSEEGDEDFEGKQ
GKILANTFITYTTQTDGDTRELERTKQYVNEAFQAGAMTCLICIASVKRNQAVWSCSGCF
CIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDCPWPCPKCRFEYKRSETPSRYYCYCGKVE
DPPLDPWLVPHSCGQVCEREFKPPCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRR
CSAKEWSCQLPCGQKLLCGQHKCENPCHAGSCQPCPRVSRQKCVCGKKVAERSCASPLWH
CDQVCGKTLPCGNHTCEQVCHVGACGECPRSGKRFCPCQKSKFSLPCTEDVPTCGDSCDK
VLECGIHRCSQRCHRGPCETCRQEVEKHCRCGKHTKRMPCHKPYLCETKCVKMRDCQKHQ
CRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNTKVTVPCG
RERTTRPPKCKEQCSRPPTCHHTSQEKHRCHFGSCPPCHQPCQKVLEKCGHLCPAPCHDQ
ALIKQTGRHQPTGPWEQPSEPAFIQTALPCPPCQVPIPMECLGKHEVSPLPCHAVGPYSC
KRVCGRILDCQNHTCMKECHKVTKTDGCTGKNKAGPECLHCEEGCSKSRPLGCLHPCILR
CHPGECPPCVQMLRIKCHCKITSLYVECRKITTADVNEKNLLSCCKNQCPKELPCGHRCK
EMCHPGECPFNCNQKVKLRCPCKRIKKELQCNKVRENQVSIECDTTCKEMKRKASEIKEA
EAKAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVELSLWQKHKYYLISVCGVVVV
VFAWYITHDVN

Sequence length

911

Interactions

View interactions

Show/Hide Unknown Diseases (9)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Benign	rs61747431	RCV005939023
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign	rs61747431	RCV005933145
Colon adenocarcinoma	Benign	rs61747431	RCV005939022
Colorectal cancer	Benign	rs61747431	RCV005939024
Lung cancer	Benign	rs61747431	RCV005933143
Melanoma	Uncertain significance	rs759682443	RCV005928997
NFXL1-related disorder	Benign; Likely benign	rs76453132, rs10005386, rs188343245, rs2053404, rs35139099, rs12651301, rs61747431, rs117334808, rs61730179, rs370816326, rs144169475, rs368101166, rs769810026, rs6818556, rs34323060	RCV003907107 RCV003919657 RCV003929590 RCV003974720 RCV003912270 RCV003984519 RCV003924605 RCV003942042 RCV003961583 RCV003917134 RCV003931513 RCV003937222 RCV003954590 RCV003982078 RCV003976687
Sarcoma	Benign	rs61747431	RCV005939025
Uterine corpus endometrial carcinoma	Benign	rs61747431	RCV005933144

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Language Disorders	Associate	25781923
Psychotic Disorders	Associate	40430072
Schizophrenia	Associate	40430072
Specific Language Disorder	Associate	25781923

NFXL1 (nuclear transcription factor, X-box binding like 1)