XXYLT1 (xyloside xylosyltransferase 1)

Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
152002
Gene name Gene Name - the full gene name approved by the HGNC.
Xyloside xylosyltransferase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
XXYLT1
Synonyms (NCBI Gene) Gene synonyms aliases
C3orf21
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q29
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0000287 Function Magnesium ion binding IDA 8982869
GO:0016266 Process O-glycan processing IDA 8982869, 22117070
GO:0030145 Function Manganese ion binding IDA 8982869
GO:0030176 Component Integral component of endoplasmic reticulum membrane IDA 22117070
GO:0035252 Function UDP-xylosyltransferase activity IDA 8982869, 22117070, 30169771
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
614552 26639 ENSG00000173950
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q8NBI6
Protein name Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase)
Protein function Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose (PubMed:22117070, PubMed:8982869).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01501 Glyco_transf_8 113 → 369 Glycosyl transferase family 8 Family
Sequence
Sequence length 393
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Other types of O-glycan biosynthesis  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Atrial fibrillation Atrial Fibrillation rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557
View all (6 more)		 29892015, 30061737
Lung carcinoma Non-Small Cell Lung Carcinoma rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355
View all (44 more)		 20876614
Show/Hide Unknown Diseases (3)
Unknown
Disease term Disease name Evidence References Source
Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation 30061737, 29892015 ClinVar
Atrial Fibrillation Atrial Fibrillation GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Show/Hide Text Mining Associations (7)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 28422717, 33429795
Lung Neoplasms Associate 28422717
Neoplasms Inhibit 33429795
Obesity Associate 29145611
Osteoporosis Associate 29145611
Tobacco Use Disorder Associate 28422717
Urinary Bladder Neoplasms Associate 40312703